ATA115486A - Verfahren zur herstellung neuer antibiotischer makrolite - Google Patents

Verfahren zur herstellung neuer antibiotischer makrolite

Info

Publication number
ATA115486A
ATA115486A AT0115486A AT115486A ATA115486A AT A115486 A ATA115486 A AT A115486A AT 0115486 A AT0115486 A AT 0115486A AT 115486 A AT115486 A AT 115486A AT A115486 A ATA115486 A AT A115486A
Authority
AT
Austria
Prior art keywords
macrolites
producing new
new antibiotic
antibiotic
producing
Prior art date
Application number
AT0115486A
Other languages
English (en)
Other versions
AT397095B (de
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858510944A external-priority patent/GB8510944D0/en
Priority claimed from GB858510943A external-priority patent/GB8510943D0/en
Priority claimed from GB858510942A external-priority patent/GB8510942D0/en
Priority claimed from GB868606103A external-priority patent/GB8606103D0/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Priority to AT0108992A priority Critical patent/AT399441B/de
Publication of ATA115486A publication Critical patent/ATA115486A/de
Application granted granted Critical
Publication of AT397095B publication Critical patent/AT397095B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/238—Cyclohexane rings substituted by two guanidine radicals, e.g. streptomycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT0115486A 1985-04-30 1986-04-29 Verfahren zur herstellung neuer antibiotischer makrolite AT397095B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT0108992A AT399441B (de) 1985-04-30 1992-05-26 Schädlingsbekämpfungsmittel und verfahren zur bekämpfung von schädlingen

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB858510944A GB8510944D0 (en) 1985-04-30 1985-04-30 Chemical compounds
GB858510943A GB8510943D0 (en) 1985-04-30 1985-04-30 Chemical compounds
GB858510942A GB8510942D0 (en) 1985-04-30 1985-04-30 Chemical compounds
GB868606103A GB8606103D0 (en) 1986-03-12 1986-03-12 Chemical compounds

Publications (2)

Publication Number Publication Date
ATA115486A true ATA115486A (de) 1993-06-15
AT397095B AT397095B (de) 1994-01-25

Family

ID=27449656

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0115486A AT397095B (de) 1985-04-30 1986-04-29 Verfahren zur herstellung neuer antibiotischer makrolite

Country Status (25)

Country Link
US (1) US4978675A (de)
JP (1) JPH0819132B2 (de)
KR (1) KR930011282B1 (de)
AT (1) AT397095B (de)
AU (1) AU596586B2 (de)
BE (1) BE904709A (de)
CA (1) CA1335368C (de)
CH (1) CH675124A5 (de)
DE (1) DE3614549C2 (de)
DK (1) DK160992C (de)
ES (4) ES8802229A1 (de)
FR (1) FR2587344B1 (de)
GB (1) GB2176182B (de)
GE (3) GEP19971046B (de)
HU (1) HU200771B (de)
IE (1) IE59070B1 (de)
IL (1) IL78621A (de)
LU (1) LU86412A1 (de)
LV (2) LV10777B (de)
NL (1) NL193420C (de)
NZ (1) NZ215997A (de)
PH (1) PH23386A (de)
PT (1) PT82485B (de)
RU (1) RU2004545C1 (de)
SE (1) SE503571C2 (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8704545A1 (es) * 1984-09-14 1987-04-01 Glaxo Group Ltd Un procedimiento para preparar un nuevo antibiotico por fer-mentacion
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
JPH085893B2 (ja) * 1985-09-13 1996-01-24 アメリカン・サイアナミツド・カンパニー マクロライド抗生物質およびその製法
US5336789A (en) * 1986-03-12 1994-08-09 American Cyanamid Company Macrolide compounds
JP2577734B2 (ja) * 1986-03-12 1997-02-05 アメリカン・サイアナミツド・カンパニー マクロライド抗生物質
GB8606108D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
IE62126B1 (en) * 1986-03-12 1994-12-14 American Cyanamid Co Macrolide compounds
GB8606123D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
BE1003039A4 (fr) * 1986-03-12 1991-11-05 American Cyanamid Co Nouveau compose antibiotique et procedes pour sa preparation.
US5185456A (en) * 1986-03-12 1993-02-09 American Cyanamid Company Macrolide compounds
GB8613790D0 (en) * 1986-06-06 1986-07-09 Glaxo Group Ltd Chemical compounds
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
US5840704A (en) * 1986-07-16 1998-11-24 Pfizer Inc. Antiparasitic agents and process for their preparation
DE3750495T2 (de) * 1986-07-24 1995-02-23 Beecham Group Plc Milbemycin-Derivate mit parasitenabtötender Aktivität, ein Verfahren zu ihrer Herstellung und die sie enthaltenden Zusammensetzungen.
ES2055695T3 (es) * 1986-09-12 1994-09-01 American Cyanamid Co Derivados 23-desoxi de compuestos ll-f28249.
US5149832A (en) * 1986-09-12 1992-09-22 American Cyanamid Company Mono and diacyl derivatives of ll-f28249 compounds
DE3750355T2 (de) * 1986-09-12 1995-04-06 American Cyanamid Co 23-Oxo(keto) und 23-Imino-Derivate von LL-F28249-Verbindungen.
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
EP0260537A1 (de) * 1986-09-12 1988-03-23 American Cyanamid Company 13-Deoxy-23-oxo(keto)- und 23-imino-Derivate von 13-Deoxy-C-076-aglykon-Verbindungen
US5234831A (en) * 1987-01-23 1993-08-10 Pfizer Inc Cultures for production of B avermectins
US5238848A (en) * 1987-01-23 1993-08-24 Pfizer Inc Cultures for production of avermectins
US5525506A (en) * 1987-01-23 1996-06-11 Pfizer Inc. Process for production of avermectins and cultures therefor
US4956479A (en) * 1987-03-06 1990-09-11 American Cyanamid Company 23-deoxy-27-chloro derivatives of LL-F28249 compounds
US4886830A (en) * 1987-03-06 1989-12-12 American Cyanamid Company Mono- and diepoxide derivatives of 23-deoxyl-LL-F28249 compounds
US4886829A (en) * 1987-03-06 1989-12-12 American Cyanamid Company 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US4871719A (en) * 1987-03-24 1989-10-03 Ciba-Geigy Corporation Composition for controlling parasites in productive livestock
EP0285561A3 (de) * 1987-03-27 1989-10-25 Ciba-Geigy Ag Parasitizide und insektizide Milbemycin-Derivate
JPS6431776A (en) * 1987-07-28 1989-02-02 Sankyo Co Novel macrolide compound and production thereof
GB8721376D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
BR8804662A (pt) * 1987-09-11 1989-04-18 American Cyanamid Co Processo para a preparacao de um composto
GB8721377D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
GB8721373D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical process
GB8721378D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical process
GB8721375D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical process
GB8721647D0 (en) * 1987-09-15 1987-10-21 Pfizer Ltd Antiparasitic agents
US5240850A (en) * 1987-10-23 1993-08-31 Pfizer Inc. Cultures for production of avermectin aglycones
PT88952B (pt) * 1987-11-09 1993-02-26 Pfizer Processo para a preparacao de avermectinas etiladas
GB8726384D0 (en) * 1987-11-11 1987-12-16 Coopers Animal Health Veterinary treatment
GB8726730D0 (en) * 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
GB8801908D0 (en) * 1988-01-28 1988-02-24 Glaxo Group Ltd Chemical compounds
GB8804440D0 (en) * 1988-02-25 1988-03-23 Pfizer Ltd Antiparasitic agents
HU9203978D0 (en) * 1988-05-10 1993-04-28 American Cyanamid Co Method for producing macrolidic compounds and preparatives containing them qs active substance by means of fermentation
GB8811036D0 (en) * 1988-05-10 1988-06-15 Glaxo Group Ltd Chemical compounds
GB8811037D0 (en) * 1988-05-10 1988-06-15 Glaxo Group Ltd Chemical compounds
GB8813150D0 (en) * 1988-06-03 1988-07-06 American Cyanamid Co Chemical compounds
GB8813760D0 (en) * 1988-06-10 1988-07-13 American Cyanamid Co Chemical process
US5428034A (en) * 1988-09-02 1995-06-27 Sankyo Co., Ltd. Milbemycin derivatives, their preparation and their use
US6001822A (en) * 1989-04-11 1999-12-14 Pfizer Inc. Antiparasitic formulations
DK0393890T3 (da) * 1989-04-11 1992-09-28 Pfizer Injicerbart præparat indeholdende 25-cyclohexyl-avermectin B1
NZ234802A (en) * 1989-08-14 1992-11-25 Merck & Co Inc Long acting injectable formulations comprising an avermectin compound and triacetin. treatment for internal and external parasites of animals
US5055486A (en) * 1989-12-22 1991-10-08 American Cyanamid Company 13-alkyl-23-imino derivative of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
US4988824A (en) * 1989-09-11 1991-01-29 Maulding Donald R Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds
JP2622197B2 (ja) * 1990-03-01 1997-06-18 三共株式会社 １３−エーテル置換ミルベマイシン誘導体
US5290804A (en) * 1991-05-01 1994-03-01 Merck & Co., Inc. Anthelmintic milbemycin analogs of novel microorganisms
EP0535734B1 (de) * 1991-09-30 1999-06-02 Merck & Co. Inc. Hydrierte Rizinusöl-enthaltende injizierbare Formulierungen mit verlängerter Wirkstoffabgabe
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
GB9402916D0 (en) * 1994-02-16 1994-04-06 Pfizer Ltd Antiparasitic agents
GB9408044D0 (en) * 1994-04-22 1994-06-15 Sod Conseils Rech Applic Conversion of ginkgolide c to ginkgolide b
DE19534366C2 (de) * 1995-09-15 2000-08-17 Asta Medica Ag Verfahren zur Herstellung von 2,3,4,6-Tetra-O-benzyl-D-glucopyranose und 2,3,4,6-Tetra-O-allyl-D-glucopyranose
PT765879E (pt) * 1995-09-29 2001-05-31 Sankyo Co Derivados 13-substituidos de milbemicina-5-oxima sua preparacao e utilizacao contra insectos e outras pragas
CA2211949A1 (en) * 1997-07-21 1999-01-29 David Farley Johnson Nonaqueous compositions for parenteral administration
DE60118132T2 (de) 2000-10-10 2006-10-19 Wyeth Anthelmintika
NZ552040A (en) * 2006-12-13 2009-04-30 Bomac Research Ltd Veterinary formulation comprising an anthelmintic compound and glyceryl acetate
DE102010064245A1 (de) 2010-12-28 2012-06-28 Bayer Animal Health Gmbh Makrocylischen Lactone und deren Verwendung und deren Kombinationen mit anderen Wirkstoffen
WO2012028556A1 (en) 2010-08-31 2012-03-08 Bayer Animal Health Gmbh Macrocyclic lactones and their use and their combinations with other active substances

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
US4550160A (en) * 1979-08-13 1985-10-29 Merck & Co., Inc. Processes for the interconversion of C-076 compounds
JPS5632481A (en) * 1979-08-23 1981-04-01 Sankyo Co Ltd Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent
US4289760A (en) * 1980-05-02 1981-09-15 Merck & Co., Inc. 23-Keto derivatives of C-076 compounds
US4457920A (en) * 1981-09-03 1984-07-03 Merck & Co., Inc. 4a-Substituted avermectin compounds
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
JPS59108785A (ja) * 1982-11-25 1984-06-23 Sankyo Co Ltd ミルベマイシン類の５−オキシム誘導体
JPS60126289A (ja) * 1983-11-14 1985-07-05 Sankyo Co Ltd ミルベマイシン類の５−カ−ボネ−ト誘導体
DK165119C (da) * 1984-06-05 1993-03-01 American Cyanamid Co Antibiotiske forbindelser betegnet ll-f28249alfa, beta, gamma, delta, epsilon, zeta, eta, theta, iota, kappa, my og ny og pharmaceutisk or pharmakologisk acceptable salte deraf samt fremgangsmaade til deres fremstilling
ES8704545A1 (es) * 1984-09-14 1987-04-01 Glaxo Group Ltd Un procedimiento para preparar un nuevo antibiotico por fer-mentacion
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina

Also Published As

Publication number Publication date
CA1335368C (en) 1995-04-25
IE59070B1 (en) 1993-12-15
AU5676786A (en) 1986-11-06
SE503571C2 (sv) 1996-07-08
IE861127L (en) 1986-10-30
JPS61280496A (ja) 1986-12-11
SE8601998D0 (sv) 1986-04-29
DE3614549A1 (de) 1987-01-02
GEP20001917B (en) 2000-01-05
NL193420C (nl) 1999-10-04
DK196586D0 (da) 1986-04-29
HU200771B (en) 1990-08-28
IL78621A0 (en) 1986-08-31
KR860008205A (ko) 1986-11-14
GB2176182B (en) 1989-02-01
BE904709A (fr) 1986-10-30
FR2587344A1 (fr) 1987-03-20
US4978675A (en) 1990-12-18
PH23386A (en) 1989-07-26
ES557851A0 (es) 1990-05-01
NL8601103A (nl) 1986-11-17
RU2004545C1 (ru) 1993-12-15
LV10314B (en) 1995-08-20
ES554444A0 (es) 1988-04-16
LV10314A (lv) 1994-10-20
ES8802522A1 (es) 1988-07-16
CH675124A5 (de) 1990-08-31
ES9000023A1 (es) 1990-05-01
AT397095B (de) 1994-01-25
KR930011282B1 (ko) 1993-11-29
ES8900093A1 (es) 1988-12-01
SE8601998L (sv) 1986-10-31
GB8610631D0 (en) 1986-06-04
DK160992B (da) 1991-05-13
IL78621A (en) 1991-06-30
HUT46012A (en) 1988-09-28
GB2176182A (en) 1986-12-17
GEP19971046B (en) 1997-11-26
ES557517A0 (es) 1988-07-16
LU86412A1 (fr) 1986-11-05
GEP19970833B (en) 1997-02-10
PT82485A (en) 1986-05-01
LV10777A (lv) 1995-08-20
DK160992C (da) 1991-11-11
ES557774A0 (es) 1988-12-01
NZ215997A (en) 1989-06-28
AU596586B2 (en) 1990-05-10
DE3614549C2 (de) 1998-03-12
FR2587344B1 (fr) 1991-04-05
ES8802229A1 (es) 1988-04-16
LV10777B (en) 1996-04-20
DK196586A (da) 1986-10-31
NL193420B (nl) 1999-06-01
PT82485B (pt) 1988-03-03
JPH0819132B2 (ja) 1996-02-28

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties
ELJ Ceased due to non-payment of the annual fee