ES8800986A1 - Un procedimiento para la produccion de un nuevo derivado de avermectina - Google Patents

Un procedimiento para la produccion de un nuevo derivado de avermectina

Info

Publication number
ES8800986A1
ES8800986A1 ES556466A ES556466A ES8800986A1 ES 8800986 A1 ES8800986 A1 ES 8800986A1 ES 556466 A ES556466 A ES 556466A ES 556466 A ES556466 A ES 556466A ES 8800986 A1 ES8800986 A1 ES 8800986A1
Authority
ES
Spain
Prior art keywords
alpha
methyl
avermectin
alkyl
penten
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES556466A
Other languages
English (en)
Other versions
ES556466A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Corp
Original Assignee
Pfizer Corp Belgium
Pfizer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27449680&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8800986(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB858518999A external-priority patent/GB8518999D0/en
Priority claimed from GB858520069A external-priority patent/GB8520069D0/en
Priority claimed from GB868610063A external-priority patent/GB8610063D0/en
Priority claimed from GB868610862A external-priority patent/GB8610862D0/en
Application filed by Pfizer Corp Belgium, Pfizer Corp filed Critical Pfizer Corp Belgium
Publication of ES8800986A1 publication Critical patent/ES8800986A1/es
Publication of ES556466A0 publication Critical patent/ES556466A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Abstract

PROCEDIMIENTO PARA PRODUCIR UN NUEVO DERIVADO DE AVERMECTINA. COMPRENDE: A) FERMENTAR UNA CEPA PRODUCTORA DE AVERMECTINA DEL ORGANISMO STREPTOMYCES AVERMITILIS, EN PRESENCIA DE UN ACIDO CARBOXILICO DE FORMULA (R2FCO2H), ENTRE 24 Y 33JC, PARA OBTENER UN COMPUESTO DE FORMULA (I); Y B) AISLAR A (I) CON UN DISOLVENTE ORGANICO NO MISCIBLE CON AGUA. SIENDO: R1, OH; R2, UN GRUPO A-RAMIFICADO, ALQUILO DE C 3 A 8, ALQUILENO Y OTROS; R3, H O METILO; R4, EL GRUPO 4K-(A-L-OLEANDROSIL-A-OLEANDROSILOXI) DE FORMULA (II). SE UTILIZAN COMO ANTIPARASITARIOS.
ES556466A 1985-07-27 1986-06-23 Un procedimiento para la produccion de un nuevo derivado de avermectina Expired ES8800986A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB858518999A GB8518999D0 (en) 1985-07-27 1985-07-27 Antiparasitic agents
GB858520069A GB8520069D0 (en) 1985-08-09 1985-08-09 Anti-parasitic agents
GB868610063A GB8610063D0 (en) 1986-04-24 1986-04-24 Antiparasitic agents
GB868610862A GB8610862D0 (en) 1986-05-02 1986-05-02 Antiparasitic agents

Publications (2)

Publication Number Publication Date
ES8800986A1 true ES8800986A1 (es) 1987-12-01
ES556466A0 ES556466A0 (es) 1987-12-01

Family

ID=27449680

Family Applications (1)

Application Number Title Priority Date Filing Date
ES556466A Expired ES8800986A1 (es) 1985-07-27 1986-06-23 Un procedimiento para la produccion de un nuevo derivado de avermectina

Country Status (31)

Country Link
US (2) US5089480A (es)
EP (1) EP0214731B1 (es)
JP (1) JPH0637501B2 (es)
CN (1) CN1007266B (es)
AP (1) AP37A (es)
AU (1) AU572402B2 (es)
BG (1) BG46601A3 (es)
CA (1) CA1339480C (es)
CY (1) CY1719A (es)
DE (1) DE3676396D1 (es)
DK (1) DK169036B1 (es)
ES (1) ES8800986A1 (es)
FI (1) FI87367C (es)
GR (1) GR861965B (es)
HK (1) HK65793A (es)
HU (1) HU195856B (es)
IE (1) IE58640B1 (es)
IL (1) IL79523A (es)
LU (1) LU88788I2 (es)
MA (1) MA20746A1 (es)
NL (1) NL950011I2 (es)
NO (2) NO165881C (es)
NZ (1) NZ216980A (es)
OA (1) OA08370A (es)
PH (1) PH23081A (es)
PL (1) PL153429B1 (es)
PT (1) PT83070B (es)
SK (1) SK278513B6 (es)
SU (1) SU1560059A3 (es)
UA (1) UA6345A1 (es)
YU (1) YU44294B (es)

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BG46601A3 (en) 1990-01-15
IE861983L (en) 1987-01-27
FI87367B (fi) 1992-09-15
NO863014L (no) 1987-01-28
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DK169036B1 (da) 1994-08-01
CN1007266B (zh) 1990-03-21
FI863065A (fi) 1987-01-28
US5451511A (en) 1995-09-19
SK278513B6 (en) 1997-08-06
CA1339480C (en) 1997-09-30
AU6056986A (en) 1987-05-14
NO165881C (no) 1991-04-24
YU134186A (en) 1987-12-31
EP0214731B1 (en) 1991-01-02
CY1719A (en) 1994-05-06
DK353486A (da) 1987-01-28
HUT44081A (en) 1988-01-28
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AP37A (en) 1989-03-11
GR861965B (en) 1986-11-26
NO863014D0 (no) 1986-07-25
DK353486D0 (da) 1986-07-25
NO1995009I1 (no) 1995-11-17
LU88788I2 (fr) 1996-11-05
PH23081A (en) 1989-04-10
HU195856B (en) 1988-07-28
SU1560059A3 (ru) 1990-04-23
YU44294B (en) 1990-04-30
FI863065A0 (fi) 1986-07-25
PT83070A (en) 1986-08-01
MA20746A1 (fr) 1987-04-01
UA6345A1 (uk) 1994-12-29
EP0214731A2 (en) 1987-03-18
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ES556466A0 (es) 1987-12-01
NO165881B (no) 1991-01-14
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US5089480A (en) 1992-02-18
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JPS6229590A (ja) 1987-02-07
NL950011I2 (nl) 1997-03-03
AU572402B2 (en) 1988-05-05
AP8600040A0 (en) 1986-08-01
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CN86105218A (zh) 1987-03-04
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