AR054380A1 - Control de parasitos en animales con derivados de n- ((feniloxi) fenil) -1,1,1-trifluorometansulfonamida y de n-(fenilsulfanil) fenil) -1,1,1-trifluorometansulfonamida - Google Patents

Control de parasitos en animales con derivados de n- ((feniloxi) fenil) -1,1,1-trifluorometansulfonamida y de n-(fenilsulfanil) fenil) -1,1,1-trifluorometansulfonamida

Info

Publication number
AR054380A1
AR054380A1 ARP060102375A ARP060102375A AR054380A1 AR 054380 A1 AR054380 A1 AR 054380A1 AR P060102375 A ARP060102375 A AR P060102375A AR P060102375 A ARP060102375 A AR P060102375A AR 054380 A1 AR054380 A1 AR 054380A1
Authority
AR
Argentina
Prior art keywords
phenyl
alkyl
group
thiocarbamoyl
animal
Prior art date
Application number
ARP060102375A
Other languages
English (en)
Original Assignee
Schering Plough Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Plough Ltd filed Critical Schering Plough Ltd
Publication of AR054380A1 publication Critical patent/AR054380A1/es

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
    • A01N47/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing >N—S—C≡(Hal)3 groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/09—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by at least two halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/46—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms
    • C07C323/49—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms to sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Veterinary Medicine (AREA)
  • Agronomy & Crop Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Se proporcionan métodos para tratar un animal con infestacion por endo- y/o ectoparásitos y/o para proteger un animal de una infestacion con endo- y/o ectoparásitos usando compuestos de N-fenil-1,1,1,-trifluorometansulfonamida, junto con métodos para hacer dichos compuestos, y métodos para usar dichos compuestos para tratar infestaciones con parásitos in vivo o ex vivo. También se proporcionan N-fenil-1,1,1-trifluorometansulfonamidas. Reivindicacion 1: Un método para tratar o proteger a un animal o planta de la infestacion con un parásito, que comprende suministrar al animal o planta una cantidad efectiva de un compuesto de N-fenil-1,1,1-trifluorometansulfonamida, una sal del mismo, o un solvato del mismo, farmacéuticamente aceptables; donde el compuesto de N-fenil-1,1,1-trifluorometansulfonamida se selecciona del grupo formado por las formulas (1a) a (1c) y una combinacion de los mismos, donde R se selecciona del grupo formado por H, alquilo, alquenilo, alquinilo, arilalquilo, cicloalquilalquilo, heterociclilalquilo, heteroarilalquilo, hidroxialquilo, alcoxialquilo, ariloxialquilo, cianoalquilo, alquilcarbonilalquilo, cicloalquilcarbonilalquilo, arilcarbonilalquilo, heterociclilcarbonilalquilo, heteroarilcarbonilalquilo, alcoxicarbonilalquilo, alquilaminocarbonilalquilo, trialquilsililalquilo, trialcoxisililalquilo, dialcoxifosfonatoalquilo, heterocicliloxialquilo, heteroariloxialquilo, alquilcarboniloxialquilo, arilcarboniloxialquilo, heterociclilcarboniloxialquilo, heteroarilcarboniloxialquilo, alcoxicarboniloxialquilo, ariloxicarboniloxialquilo, heterocicliloxicarboniloxialquilo, heteroariloxicarboniloxialquilo, alquilaminocarboniloxialquilo, arilaminocarboniloxialquilo, heterociclilaminocarboniloxialquilo, heteroarilaminocarboniloxialquilo, alquilcarbonilaminoalquilo, arilcarbonilaminoalquilo, heterociclilcarbonilaminoalquilo, heteroarilcarbonilaminoalquilo, alquilsulfonilalquilo, arilsulfonilalquilo, heterociclilsulfonilalquilo, heteroarilsulfonilalquilo, alacanoílo, aroílo, heterocicloílo, heteroaroilo, alcoxicarbonilo, ariloxicarbonilo, heterocicliloxicarbonilo, heteroariloxicarbonilo, N-alquil carbamoílo, N-aril carbamoílo, N- heterociclilcarbamoílo, N-heteroaril carbamoílo, N-alquil tiocarbamoílo, N-aril tiocarbamoílo, N-heterociclil tiocarbamoílo, N-heteroaril tiocarbamoílo, alquilsulfonilo, arilsulfonilo, heterociclilsulfonilo y heteroarilsulfonilo; donde R1-R9 son independientemente seleccionados del grupo formado por H, ciano, nitro, halo, y una porcion opcionalmente sustituida seleccionada del grupo formado por alquilo, cicloalquilo, arilo, heterociclilo, heteroarilo, alcoxi, cicloalcoxi, ariloxi, heteroariloxi, heterocicliloxi, haloalquilo, y haloalcoxi, donde X se selecciona del grupo formado por O, S, sulfinilo, sulfonilo y NR10; y donde R10 es H o alquilo.
ARP060102375A 2005-06-09 2006-06-07 Control de parasitos en animales con derivados de n- ((feniloxi) fenil) -1,1,1-trifluorometansulfonamida y de n-(fenilsulfanil) fenil) -1,1,1-trifluorometansulfonamida AR054380A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68889805P 2005-06-09 2005-06-09

Publications (1)

Publication Number Publication Date
AR054380A1 true AR054380A1 (es) 2007-06-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060102375A AR054380A1 (es) 2005-06-09 2006-06-07 Control de parasitos en animales con derivados de n- ((feniloxi) fenil) -1,1,1-trifluorometansulfonamida y de n-(fenilsulfanil) fenil) -1,1,1-trifluorometansulfonamida

Country Status (10)

Country Link
US (1) US20060281695A1 (es)
EP (1) EP1890547A2 (es)
JP (1) JP2008545788A (es)
AR (1) AR054380A1 (es)
CA (1) CA2609574A1 (es)
MX (1) MX2007015729A (es)
PE (1) PE20070108A1 (es)
TW (1) TW200718358A (es)
WO (1) WO2006135648A2 (es)
ZA (1) ZA200710513B (es)

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ZA200710513B (en) 2008-12-31
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MX2007015729A (es) 2008-02-21
WO2006135648A2 (en) 2006-12-21
JP2008545788A (ja) 2008-12-18
CA2609574A1 (en) 2006-12-21
US20060281695A1 (en) 2006-12-14
PE20070108A1 (es) 2007-02-09
TW200718358A (en) 2007-05-16

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