LU88788I2 - Doramectin - Google Patents

Doramectin

Info

Publication number
LU88788I2
LU88788I2 LU88788C LU88788C LU88788I2 LU 88788 I2 LU88788 I2 LU 88788I2 LU 88788 C LU88788 C LU 88788C LU 88788 C LU88788 C LU 88788C LU 88788 I2 LU88788 I2 LU 88788I2
Authority
LU
Luxembourg
Prior art keywords
doramectin
Prior art date
Application number
LU88788C
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27449680&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU88788(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB858518999A external-priority patent/GB8518999D0/en
Priority claimed from GB858520069A external-priority patent/GB8520069D0/en
Priority claimed from GB868610063A external-priority patent/GB8610063D0/en
Priority claimed from GB868610862A external-priority patent/GB8610862D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of LU88788I2 publication Critical patent/LU88788I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LU88788C 1985-07-27 1986-07-22 Doramectin LU88788I2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB858518999A GB8518999D0 (en) 1985-07-27 1985-07-27 Antiparasitic agents
GB858520069A GB8520069D0 (en) 1985-08-09 1985-08-09 Anti-parasitic agents
GB868610063A GB8610063D0 (en) 1986-04-24 1986-04-24 Antiparasitic agents
GB868610862A GB8610862D0 (en) 1986-05-02 1986-05-02 Antiparasitic agents

Publications (1)

Publication Number Publication Date
LU88788I2 true LU88788I2 (fr) 1996-11-05

Family

ID=27449680

Family Applications (1)

Application Number Title Priority Date Filing Date
LU88788C LU88788I2 (fr) 1985-07-27 1986-07-22 Doramectin

Country Status (31)

Country Link
US (2) US5089480A (fr)
EP (1) EP0214731B1 (fr)
JP (1) JPH0637501B2 (fr)
CN (1) CN1007266B (fr)
AP (1) AP37A (fr)
AU (1) AU572402B2 (fr)
BG (1) BG46601A3 (fr)
CA (1) CA1339480C (fr)
CY (1) CY1719A (fr)
DE (1) DE3676396D1 (fr)
DK (1) DK169036B1 (fr)
ES (1) ES8800986A1 (fr)
FI (1) FI87367C (fr)
GR (1) GR861965B (fr)
HK (1) HK65793A (fr)
HU (1) HU195856B (fr)
IE (1) IE58640B1 (fr)
IL (1) IL79523A (fr)
LU (1) LU88788I2 (fr)
MA (1) MA20746A1 (fr)
NL (1) NL950011I2 (fr)
NO (2) NO165881C (fr)
NZ (1) NZ216980A (fr)
OA (1) OA08370A (fr)
PH (1) PH23081A (fr)
PL (1) PL153429B1 (fr)
PT (1) PT83070B (fr)
SK (1) SK278513B6 (fr)
SU (1) SU1560059A3 (fr)
UA (1) UA6345A1 (fr)
YU (1) YU44294B (fr)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR940004098B1 (ko) * 1984-09-14 1994-05-13 아메리칸 사이아나미드 캄파니 신규 항생제 화합물의 제조 방법
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
JPH085893B2 (ja) * 1985-09-13 1996-01-24 アメリカン・サイアナミツド・カンパニー マクロライド抗生物質およびその製法
ES2054664T3 (es) * 1986-03-12 1994-08-16 American Cyanamid Co Compuestos macrolidos.
EP0254583B1 (fr) * 1986-07-24 1994-09-07 Beecham Group Plc Dérivés de la milbémycine à activité parasiticide, un procédé pour leur préparation et les compositions les contenant
US4886828A (en) * 1986-09-12 1989-12-12 American Cyanamid Company Δ22 -derivatives of LL-F28249 compounds
EP0260537A1 (fr) * 1986-09-12 1988-03-23 American Cyanamid Company Dérivés 13-déoxy-23-oxo(céto) et 23-imino des composés de 13-déoxy-C-076-aglycone
EP0262384B1 (fr) * 1986-09-12 1992-11-04 American Cyanamid Company Dérivés 23-déoxy des composés LL-F28249
US5149832A (en) * 1986-09-12 1992-09-22 American Cyanamid Company Mono and diacyl derivatives of ll-f28249 compounds
US5019589A (en) * 1986-09-12 1991-05-28 American Cyanamid Company Δ23 -LL-F28249 compounds
US5234831A (en) * 1987-01-23 1993-08-10 Pfizer Inc Cultures for production of B avermectins
ES2058244T3 (es) * 1987-01-23 1994-11-01 Pfizer Procedimiento para produccion de avermectinas y cultivos para el mismo.
US5525506A (en) * 1987-01-23 1996-06-11 Pfizer Inc. Process for production of avermectins and cultures therefor
IN167980B (fr) * 1987-01-23 1991-01-19 Pfizer
US5238848A (en) * 1987-01-23 1993-08-24 Pfizer Inc Cultures for production of avermectins
US4956479A (en) * 1987-03-06 1990-09-11 American Cyanamid Company 23-deoxy-27-chloro derivatives of LL-F28249 compounds
US4886830A (en) * 1987-03-06 1989-12-12 American Cyanamid Company Mono- and diepoxide derivatives of 23-deoxyl-LL-F28249 compounds
US4851428A (en) * 1987-03-06 1989-07-25 American Cyanamid Company Mono- and diepoxide derivatives of Δ22-LL-F28249 compounds
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
NZ225364A (en) * 1987-07-20 1990-04-26 Merck & Co Inc 5,23-di-hydroxy 25-(4-methyl-hex-2-en-2-yl) milbemycin and parasiticidal compositions
JPS6431776A (en) * 1987-07-28 1989-02-02 Sankyo Co Novel macrolide compound and production thereof
GB8721647D0 (en) * 1987-09-15 1987-10-21 Pfizer Ltd Antiparasitic agents
DE3881147T2 (de) * 1987-10-23 1993-09-02 Pfizer Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen.
US5240850A (en) * 1987-10-23 1993-08-31 Pfizer Inc. Cultures for production of avermectin aglycones
EP0319142B1 (fr) * 1987-11-03 1994-04-06 Beecham Group Plc Intermédiaires pour la preparation des antibiotiques macrolides à activité anthelmintique
ES2045146T3 (es) * 1987-11-09 1994-01-16 Pfizer Avermectinas etiladas.
GB8726730D0 (en) 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
GB8807280D0 (en) * 1988-03-26 1988-04-27 Pfizer Ltd Antiparasitic agents
GB8809232D0 (en) * 1988-04-19 1988-05-25 Pfizer Ltd Antiparasitic agents
GB8815967D0 (en) * 1988-07-05 1988-08-10 Pfizer Ltd Antiparasitic agents
US5015662A (en) * 1988-10-18 1991-05-14 Merck & Co., Inc. Anthelmintic bioconversion products
OA09249A (fr) * 1988-12-19 1992-06-30 Lilly Co Eli Composés de macrolides.
NZ231773A (en) * 1988-12-23 1992-09-25 Merck & Co Inc Avermectin derivatives, preparation and parasiticidal pharmaceutical compositions thereof
US5015630A (en) * 1989-01-19 1991-05-14 Merck & Co., Inc. 5-oxime avermectin derivatives
US4897383A (en) * 1989-02-13 1990-01-30 Merck & Co., Inc. Avermectin derivatives
US6001822A (en) * 1989-04-11 1999-12-14 Pfizer Inc. Antiparasitic formulations
US5030622A (en) * 1989-06-02 1991-07-09 Merck & Co., Inc. Avermectin derivatives
US5057499A (en) * 1989-06-02 1991-10-15 Merck & Co. Inc. Avermectin derivatives
US5023241A (en) * 1989-07-31 1991-06-11 Merck & Co., Inc. Avermectin derivatives
AU631693B2 (en) * 1989-10-30 1992-12-03 Eli Lilly And Company A83543 recovery process
US5830875A (en) * 1989-10-30 1998-11-03 Merck & Co., Inc. 24-and 25-substituted avermectin and milbemycin derivatives
US5188944A (en) * 1990-06-22 1993-02-23 Merck & Co., Inc. Process for the glycosylation of avermectin agylcones
US5208222A (en) * 1991-03-28 1993-05-04 Merck & Co., Inc. 4"-and 4'-alkylthio avermectin derivatives
US5240915A (en) * 1991-10-15 1993-08-31 Merck & Co., Inc. Avermectin derivatives
AU660205B2 (en) * 1991-12-23 1995-06-15 Virbac, Inc Systemic control of parasites
GB9201505D0 (en) * 1992-01-24 1992-03-11 Pfizer Ltd Antiparasitic agents
GB9205007D0 (en) * 1992-03-07 1992-04-22 Pfizer Ltd Antiparasitic agents
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
US5241083A (en) * 1992-07-01 1993-08-31 Merck & Co., Inc. Process for converting the 13-α-hydroxy group of avermectin aglycones
US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
JPH08503551A (ja) * 1992-11-20 1996-04-16 ブリティッシュ・テクノロジー・グループ・リミテッド 画像再生
US5292647A (en) * 1992-11-30 1994-03-08 Eli Lilly And Company Strain of streptomyces for producing avermectins and processes therewith
US5411946A (en) * 1993-02-24 1995-05-02 Merck & Co., Inc. Avermectin derivatives
EP0688332B1 (fr) * 1993-03-12 1997-03-26 Dowelanco Nouveaux composes a83543 et procede de production desdits composes
GB9315108D0 (en) * 1993-07-21 1993-09-01 Pfizer Ltd Antiparasitic agents
BR9407141A (pt) * 1993-07-23 1996-09-17 Pfizer Método para a precipatação de avermectinas naturais
KR100186946B1 (ko) * 1993-10-05 1999-04-01 알렌 제이.스피겔 도라멕틴의 구충활성 중간체 및 도라멕틴의 제조방법
TW327125B (en) * 1994-02-07 1998-02-21 Merck & Co Inc Composition and method for protecting against pine exhausted
DE4427766A1 (de) * 1994-08-05 1996-02-08 Basf Ag Verfahren zur Herstellung flüssigkristalliner Mischungen
WO1996019920A1 (fr) * 1994-12-27 1996-07-04 Pfizer Pharmaceuticals Inc. Compositions utilisees pour traiter les infections des arbres par les nematodes
US6001981A (en) * 1996-06-13 1999-12-14 Dow Agrosciences Llc Synthetic modification of Spinosyn compounds
US6165987A (en) * 1996-07-30 2000-12-26 Harvey; Colin Manson Anthelmintic formulations
AU4139797A (en) * 1997-06-09 1998-12-30 Nauchno-Proizvodstvennoye Obiedinenie "Farmbiomed" (streptomyces avermitilis) strain, method for separating avermectin complexe s and preparations for protecting plants and animals
RU2138268C1 (ru) * 1997-09-22 1999-09-27 Мосин Владимир Александрович Средство, подавляющее пролиферацию и вызывающее гибель опухолевых клеток, при этом защищающее нормальные клетки
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
GB9825402D0 (en) * 1998-11-19 1999-01-13 Pfizer Ltd Antiparasitic formulations
DE19913534A1 (de) * 1999-03-25 2000-10-05 Bayer Ag Avermectinderivate
US6787342B2 (en) 2000-02-16 2004-09-07 Merial Limited Paste formulations
KR20020067781A (ko) * 2001-02-19 2002-08-24 주식회사 엘지씨아이 구충용 이버멕틴 주사제 조성물 및 그 제조방법
EP2347654B1 (fr) 2001-09-17 2019-02-27 Elanco US Inc. Formulation pour controller les tiques et poux du betail
WO2005082852A1 (fr) 2004-03-02 2005-09-09 Adeka Corporation Amines stériquement encombrées faiblement basiques comportant des structures de carbonate, compositions de résines synthétiques et compositions de revêtement
CN101065352A (zh) 2004-09-23 2007-10-31 先灵-普劳有限公司 使用新的三氟甲磺酰苯胺肟醚衍生物控制动物中的寄生虫
CA2587495A1 (fr) * 2004-11-19 2006-05-26 Schering-Plough Ltd. Lutte contre des parasites chez les animaux au moyen de derives parasiticides de 2-phenyl-3-(1h-pyrrol-2-yl) acrylonitrile
MX2007015729A (es) * 2005-06-09 2008-02-21 Schering Plough Ltd Control de parasitos en animales con derivados de n-[(feniloxi)fenil]-1,1,1-trifluorometansulfonamida y de n[(fenilsulfanil)fenil]-1,1,1-trifluorometansulfonamida.
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
EP1849363A1 (fr) * 2006-03-09 2007-10-31 Cheminova A/S Combinations synergiques d'un plaguicide agoniste des canaux à chlorure actives par le glutamate ou le GABA et au moins un d'entre la vitamine E et la niacin
US20070238700A1 (en) * 2006-04-10 2007-10-11 Winzenberg Kevin N N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
WO2008076259A1 (fr) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Promédicaments de florfenicol solubles dans l'eau et analogues
US8044230B2 (en) * 2006-12-13 2011-10-25 Intervet Inc. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
KR100831643B1 (ko) * 2007-04-10 2008-05-22 류충오 연결 조인트 및 이를 구비한 복합재료 드라이브 샤프트어셈블리
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
NO2957284T3 (fr) 2007-06-27 2018-06-16
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TWI468407B (zh) 2008-02-06 2015-01-11 Du Pont 中離子農藥
US8314252B2 (en) * 2008-07-30 2012-11-20 Intervet Inc. Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol
AU2009322206B2 (en) 2008-12-04 2015-03-05 Boehringer Ingelheim Animal Health USA Inc. Dimeric avermectin and milbemycin derivatives
JP2012517994A (ja) 2009-02-16 2012-08-09 ファイザー・インク 高投与量ドラメクチン製剤
MX2011009678A (es) 2009-03-17 2011-09-30 Intervet Int Bv Sistema de suministro de farmaco de lactona macrociclica.
US20120122679A1 (en) 2009-08-05 2012-05-17 E. I. Du Pont De Nemours And Company Mesoionic pesticides
EP2462125A2 (fr) 2009-08-05 2012-06-13 E. I. du Pont de Nemours and Company Pesticides méso-ioniques
UA107804C2 (en) 2009-08-05 2015-02-25 Du Pont Mixtures of pesticides mezoionnyh
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
WO2011043962A2 (fr) 2009-10-07 2011-04-14 Wyeth Llc Compositions comprenant un adjuvant, un macrolide et un antigène protéique et procédés d'utilisation de celles-ci
MX2012004523A (es) 2009-10-19 2012-05-08 Intervet Int Bv Metodo y formulacion para el control de parasitos.
US8980896B2 (en) 2009-12-17 2015-03-17 Merial, Inc. Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
MA34247B1 (fr) 2010-05-27 2013-05-02 Du Pont Forme cristalline du 4-[5-[3-chloro-5-(trifluorométhyl) phényl] -4,5-dihydro-5-(trifluorométhyl)-3-isoxazolyl]-n-[2-oxo-2-[(2, 2,2-trifluoroéthyl) amino] éthyl]-1-naphtalènecarboxamide
AR081970A1 (es) 2010-06-24 2012-10-31 Intervet Int Bv Formulacion inyectable de una lactona macrociclica y levamisol, formulacion y uso veterinario
WO2012087630A1 (fr) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Composés de pyridine et de pyrimidine utilisés pour lutter contre des nuisibles invertébrés
US8715711B2 (en) 2011-12-02 2014-05-06 Merial Limited Long-acting injectable moxidectin formulations and novel moxidectin crystal forms
WO2013158422A1 (fr) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Composés hétérocycliques pour la lutte contre des animaux nuisibles invertébrés
CN103356687B (zh) * 2012-10-19 2016-06-01 厦门大学 一种伊维菌素及其衍生物的用途
EP2886640A1 (fr) 2013-12-18 2015-06-24 Riga Technical University Procédé d'isolation pour milbemycine A3 et A4
KR101789736B1 (ko) 2017-08-30 2017-10-25 대한민국 이버멕틴을 함유하는 조피볼락의 클라비네마 마리에 감염 구제용 조성물
WO2022034226A1 (fr) 2020-08-14 2022-02-17 Universidad De Navarra Compositions d'avermectine et de milbemycine pour inhalation

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4134973A (en) * 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
PH15982A (en) * 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
US4171314A (en) * 1977-12-19 1979-10-16 Merck & Co., Inc. 13-Halo and 13-deoxy C-076 compounds
PH16612A (en) * 1977-12-19 1983-11-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds
US4429042A (en) * 1978-09-08 1984-01-31 Merck & Co., Inc. Strain of Streptomyces for producing antiparasitic compounds
US4328335A (en) * 1979-08-13 1982-05-04 Merck & Co., Inc. Process for the interconversion of C-076 compounds
US4285963A (en) * 1980-08-07 1981-08-25 Merck & Co., Inc. Novel derivatives of C-076 compounds
US4378353A (en) * 1981-02-17 1983-03-29 Merck & Co., Inc. Novel C-076 compounds
US4333925A (en) * 1981-05-11 1982-06-08 Merck & Co., Inc. Derivatives of C-076 compounds
JPS5878594A (ja) * 1981-11-06 1983-05-12 Sankyo Co Ltd 抗生物質ｂ−４１ｄ、ｅ及びｇの製造法
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
US4427663A (en) * 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
US4423204A (en) * 1982-09-02 1983-12-27 The Upjohn Company Amorphous copolyamide from lactam, dicarboxylic acid and bisimidazoline
JPS5953403A (ja) * 1982-09-21 1984-03-28 Sankyo Co Ltd 殺ダニ性組成物
US4469682A (en) * 1983-01-28 1984-09-04 Merck & Co., Inc. Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use
KR940004098B1 (ko) * 1984-09-14 1994-05-13 아메리칸 사이아나미드 캄파니 신규 항생제 화합물의 제조 방법
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
GB8502925D0 (en) * 1985-02-05 1985-03-06 Ici Plc Macrocyclic lactones
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
NZ216908A (en) * 1985-07-29 1989-06-28 Merck & Co Inc Avermectin derivatives
JPH085893B2 (ja) * 1985-09-13 1996-01-24 アメリカン・サイアナミツド・カンパニー マクロライド抗生物質およびその製法
EP0235085A1 (fr) * 1986-02-20 1987-09-02 Ciba-Geigy Ag Dérivés de milbémycine substitués en position 13-bêta, leur préparation et utilisation comme agents ecto- et endoparasitaires pour le traitement d'animaux et de plantes
GB8606120D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Process
US4831016A (en) * 1986-10-31 1989-05-16 Merck & Co., Inc. Reduced avermectin derivatives
GB8815967D0 (en) * 1988-07-05 1988-08-10 Pfizer Ltd Antiparasitic agents
US5422349A (en) * 1992-08-14 1995-06-06 G. D. Seale & Co. Morpholino-oxazinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension

Also Published As

Publication number Publication date
YU134186A (en) 1987-12-31
CN86105218A (zh) 1987-03-04
IE861983L (en) 1987-01-27
DK353486A (da) 1987-01-28
MA20746A1 (fr) 1987-04-01
PT83070B (pt) 1989-02-28
OA08370A (fr) 1988-02-29
CA1339480C (fr) 1997-09-30
JPS6229590A (ja) 1987-02-07
AU6056986A (en) 1987-05-14
CN1007266B (zh) 1990-03-21
US5089480A (en) 1992-02-18
NL950011I1 (nl) 1995-12-01
US5451511A (en) 1995-09-19
SK278513B6 (en) 1997-08-06
NO165881B (no) 1991-01-14
CY1719A (en) 1994-05-06
GR861965B (en) 1986-11-26
NZ216980A (en) 1988-10-28
SU1560059A3 (ru) 1990-04-23
FI863065A0 (fi) 1986-07-25
FI863065A (fi) 1987-01-28
PH23081A (en) 1989-04-10
PT83070A (en) 1986-08-01
BG46601A3 (en) 1990-01-15
NO165881C (no) 1991-04-24
IL79523A (en) 1990-02-09
AP8600040A0 (en) 1986-08-01
AP37A (en) 1989-03-11
NO1995009I1 (no) 1995-11-17
FI87367C (fi) 1992-12-28
NO863014D0 (no) 1986-07-25
FI87367B (fi) 1992-09-15
DE3676396D1 (de) 1991-02-07
IE58640B1 (en) 1993-10-20
HU195856B (en) 1988-07-28
JPH0637501B2 (ja) 1994-05-18
PL260806A1 (en) 1987-11-16
EP0214731A3 (en) 1987-07-22
HK65793A (en) 1993-07-16
EP0214731B1 (fr) 1991-01-02
YU44294B (en) 1990-04-30
UA6345A1 (uk) 1994-12-29
HUT44081A (en) 1988-01-28
ES8800986A1 (es) 1987-12-01
DK353486D0 (da) 1986-07-25
PL153429B1 (en) 1991-04-30
NO863014L (no) 1987-01-28
DK169036B1 (da) 1994-08-01
ES556466A0 (es) 1987-12-01
EP0214731A2 (fr) 1987-03-18
NL950011I2 (nl) 1997-03-03
AU572402B2 (en) 1988-05-05

Similar Documents

Publication Publication Date Title
LU88788I2 (fr) Doramectin
ATA155686A (de) Giesspfannenkopf
NO171144C (no) Benfiskeringssystem
ATA4386A (de) Maishaecksler
BR8501248A (pt) Sulcador pontiagudo
ATA257585A (de) Ru-deruebungsgeraet
ATA173385A (de) Stiegenlift
BR6502051U (pt) Mult-sinalizador
BR6501483U (pt) Expremedor
BR8505459A (pt) Poli-cacamba-pa
BR8505432A (pt) Lenco boca-a-boca
BR8505260A (pt) Raladeira
BR8505025A (pt) Bucha
BR8504833A (pt) Cefalometro
BR8504276A (pt) Garagem-armario
BR8503827A (pt) Patrulhometro
BR8503788A (pt) Semeadeira-adubadeira
BR8503311A (pt) Cistotomico
BR8501720A (pt) Semeadeira-adubadeira
BR8501687A (pt) Phonex
BR8500544A (pt) Bi-telefone
BR8500399A (pt) Pedalkarte
BR6502073U (pt) Lanternim
BR8505898A (pt) Altenador magnetonomo
BR6501852U (pt) Control-temper