ES8704460A1 - Un procedimiento para preparar derivados de 2-piridin-tiol - Google Patents
Un procedimiento para preparar derivados de 2-piridin-tiolInfo
- Publication number
- ES8704460A1 ES8704460A1 ES547604A ES547604A ES8704460A1 ES 8704460 A1 ES8704460 A1 ES 8704460A1 ES 547604 A ES547604 A ES 547604A ES 547604 A ES547604 A ES 547604A ES 8704460 A1 ES8704460 A1 ES 8704460A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- pyridine
- alkyl
- image
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE DERIVADOS DE 2-PIRIDIN-TIOL. CONSISTENTE EN LA OBTENCION DE UN COMPUESTO DE FORMULA (I) EN LA QUE R ES HIDROGENO O ALQUILO CON 1 A 4 CARBONOS; Z ES FENILO, OPCIONALMENTE SUSTITUIDO CON UNO O MAS ATOMOS DE HALOGENO O GRUPOS ALQUILO CON 1 A 4 CARBONOS; R1 Y R2 SON HIDROGENO, ALQUILO CON 1 A 4 CARBONOS, O ALQUILFENILO CON DETERMINADAS CONDICIONES; Y EL SUSTITUYENTE -COZ ESTA UNIDO AL ANILLO DE PIRIDINA EN POSICION 3 O 4; MEDIANTE REACCION DE UN DERIVADO DE 2-HALOPIRIDINA DE FORMULA (II) CON UN COMPUESTO DE TIOL DE FORMULA (III). ALTERNATIVAMENTE, POR REACCION DE OTROS DERIVADOS DE PIRIDINA CON LOS CORRESPONDIENTES DERIVADOS AMINICOS O CON FTALIMIDA-K. DE APLICACION POR SU ACTIVIDAD GASTROCITOPROTECTORA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU843775A HU192875B (en) | 1984-10-05 | 1984-10-05 | Process for preparing 2-pyridinethiol derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES547604A0 ES547604A0 (es) | 1987-04-01 |
| ES8704460A1 true ES8704460A1 (es) | 1987-04-01 |
Family
ID=10965437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES547604A Expired ES8704460A1 (es) | 1984-10-05 | 1985-10-04 | Un procedimiento para preparar derivados de 2-piridin-tiol |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4713388A (es) |
| EP (1) | EP0177907B1 (es) |
| JP (1) | JPS6191172A (es) |
| KR (1) | KR860003212A (es) |
| CN (1) | CN85107284A (es) |
| AT (1) | ATE34739T1 (es) |
| AU (1) | AU579665B2 (es) |
| DD (1) | DD238384A5 (es) |
| DE (1) | DE3563048D1 (es) |
| DK (1) | DK455285A (es) |
| ES (1) | ES8704460A1 (es) |
| FI (1) | FI853866L (es) |
| GR (1) | GR852409B (es) |
| HU (1) | HU192875B (es) |
| IL (1) | IL76577A0 (es) |
| IN (1) | IN162570B (es) |
| NO (1) | NO853935L (es) |
| PH (1) | PH21435A (es) |
| PL (1) | PL146371B1 (es) |
| PT (1) | PT81255B (es) |
| SU (1) | SU1346042A3 (es) |
| YU (1) | YU158385A (es) |
| ZA (1) | ZA857676B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1339423C (en) * | 1988-09-14 | 1997-09-02 | Yuji Ono | Pyridine compounds and pharmaceutical use thereof |
| EP0522606B1 (en) * | 1991-05-10 | 1996-04-03 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, their production and use |
| AR029289A1 (es) * | 2000-07-05 | 2003-06-18 | Ishihara Sangyo Kaisha | Derivado de benzoilpiridina o su sal, fungicida que lo contiene como un ingrediente activo, su proceso de produccion e intermediario para producirlo |
| TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
| CN102358738A (zh) | 2003-07-30 | 2012-02-22 | 里格尔药品股份有限公司 | 2,4-嘧啶二胺化合物及其预防和治疗自体免疫疾病的用途 |
| EP1817303A2 (en) * | 2004-10-29 | 2007-08-15 | Rigel Pharmaceuticals, Inc. | Substituted pyridines with activity on syk kinase |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT238200B (de) * | 1962-03-27 | 1965-01-25 | Degussa | Verfahren zur Herstellung von neuen Pyridinderivaten |
| JPS552920A (en) * | 1978-06-23 | 1980-01-10 | Natl Res Inst For Metals | Method of detecting surface dfect of non-magnetic material |
| US4304781A (en) * | 1978-11-30 | 1981-12-08 | John Wyeth & Brother Limited | Treatment of ulcers and hypertension |
| HU194830B (en) * | 1984-10-05 | 1988-03-28 | Richter Gedeon Vegyeszet | Process for the production of derivatives of piridine |
-
1984
- 1984-10-05 HU HU843775A patent/HU192875B/hu not_active IP Right Cessation
-
1985
- 1985-09-24 PH PH32832A patent/PH21435A/en unknown
- 1985-10-03 US US06/783,875 patent/US4713388A/en not_active Expired - Fee Related
- 1985-10-04 NO NO853935A patent/NO853935L/no unknown
- 1985-10-04 IN IN778/MAS/85A patent/IN162570B/en unknown
- 1985-10-04 AU AU48328/85A patent/AU579665B2/en not_active Expired - Fee Related
- 1985-10-04 DD DD85281464A patent/DD238384A5/de unknown
- 1985-10-04 EP EP85112599A patent/EP0177907B1/de not_active Expired
- 1985-10-04 DE DE8585112599T patent/DE3563048D1/de not_active Expired
- 1985-10-04 CN CN198585107284A patent/CN85107284A/zh active Pending
- 1985-10-04 SU SU853959903A patent/SU1346042A3/ru active
- 1985-10-04 IL IL76577A patent/IL76577A0/xx unknown
- 1985-10-04 PL PL1985255643A patent/PL146371B1/pl unknown
- 1985-10-04 DK DK455285A patent/DK455285A/da not_active Application Discontinuation
- 1985-10-04 ES ES547604A patent/ES8704460A1/es not_active Expired
- 1985-10-04 AT AT85112599T patent/ATE34739T1/de not_active IP Right Cessation
- 1985-10-04 GR GR852409A patent/GR852409B/el unknown
- 1985-10-04 JP JP60221714A patent/JPS6191172A/ja active Pending
- 1985-10-04 YU YU01583/85A patent/YU158385A/xx unknown
- 1985-10-04 FI FI853866A patent/FI853866L/fi not_active Application Discontinuation
- 1985-10-04 ZA ZA857676A patent/ZA857676B/xx unknown
- 1985-10-04 PT PT81255A patent/PT81255B/pt unknown
- 1985-10-05 KR KR1019850007352A patent/KR860003212A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0177907A1 (de) | 1986-04-16 |
| JPS6191172A (ja) | 1986-05-09 |
| HU192875B (en) | 1987-07-28 |
| ATE34739T1 (de) | 1988-06-15 |
| IL76577A0 (en) | 1986-02-28 |
| US4713388A (en) | 1987-12-15 |
| DD238384A5 (de) | 1986-08-20 |
| CN85107284A (zh) | 1986-06-10 |
| DK455285A (da) | 1986-04-06 |
| AU579665B2 (en) | 1988-12-01 |
| NO853935L (no) | 1986-04-07 |
| ZA857676B (en) | 1986-06-25 |
| EP0177907B1 (de) | 1988-06-01 |
| DE3563048D1 (en) | 1988-07-07 |
| ES547604A0 (es) | 1987-04-01 |
| PL255643A1 (en) | 1987-01-12 |
| KR860003212A (ko) | 1986-05-21 |
| FI853866L (fi) | 1986-04-06 |
| YU158385A (en) | 1988-04-30 |
| IN162570B (es) | 1988-06-11 |
| SU1346042A3 (ru) | 1987-10-15 |
| PT81255A (en) | 1985-11-01 |
| DK455285D0 (da) | 1985-10-04 |
| PL146371B1 (en) | 1989-01-31 |
| FI853866A0 (fi) | 1985-10-04 |
| AU4832885A (en) | 1986-04-10 |
| GR852409B (es) | 1986-02-04 |
| HUT38907A (en) | 1986-07-28 |
| PH21435A (en) | 1987-10-15 |
| PT81255B (en) | 1987-03-23 |
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