MY101771A - Antiparasitic agents and process for their preparation. - Google Patents

Antiparasitic agents and process for their preparation.

Info

Publication number
MY101771A
MY101771A MYPI87001126A MYPI19871126A MY101771A MY 101771 A MY101771 A MY 101771A MY PI87001126 A MYPI87001126 A MY PI87001126A MY PI19871126 A MYPI19871126 A MY PI19871126A MY 101771 A MY101771 A MY 101771A
Authority
MY
Malaysia
Prior art keywords
double bond
absent
alpha
alkyl
pentene
Prior art date
Application number
MYPI87001126A
Inventor
John Desmond Prof Bu'lock
Alexander Crossan Dr Goudie
Stephen Paul Gibson
Kelvin Scott Dr Holdom
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858518999A external-priority patent/GB8518999D0/en
Priority claimed from GB858520069A external-priority patent/GB8520069D0/en
Priority claimed from GB868610063A external-priority patent/GB8610063D0/en
Priority claimed from GB868610862A external-priority patent/GB8610862D0/en
Priority claimed from EP86305604A external-priority patent/EP0214731B1/en
Application filed by Pfizer filed Critical Pfizer
Publication of MY101771A publication Critical patent/MY101771A/en

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

THE INVENTION PROVIDES NOVEL COMPOUNDS HAVING THE FORMULA:(FORMULA 1)WHEREIN THE BROKEN LINE AT THE 22-23 POSITION REPRESENTS AN OPTIONAL DOUBLE BOND AND WHEREIN R1 IS H OR OH AND THE DOUBLE BOND IS ABSENT, OR, THE DOUBLE BOND IS PRESENT AND R1 IS ABSENT; R2 IS AN ALPHA-BRANCHED C3-C8 ALKYL, ALKENYL, ALKYNYL, ALKOXYALKYL OR ALKYLTHIOALKYL GROUP; A C3-C8 CYCLOALKYL, C5-C8 CYCLOALKENYL OR C5-C8 CYCLOALKYLALKYL GROUP, ANY OF WHICH MAY OPTIONALLY BE SUBSTITUTED BY METHYLENE OR ONE OR MORE C1-C4 ALKYL GROUPS OR HALO ATOMS; OR A 3 TO 6 MEMBERED OXYGEN OR SULPHUR CONTAINING HETEROCYCLIC RING WHICH MAY OPTIONALLY BE SUBSTITUTED BY ONE OR MORE C1-C4 ALKYL GROUPS OR HALO ATOMS; R3 IS HYDROGEN OR METHYL; R4 IS H OR 4''-(ALPHA-L-OLEANDROSYL)-ALPHA-L-OLEANDROSYLOXY, WITH THE PROVISO THAT WHEN R2 IS ALKYL IT IS NOT ISOPROPYL OR SEC-BUTYL, AND WHEN R4 IS H, R1 IS OH, AND THE DOUBLE BOND IS ABSENT, R2 IS NOT 2-BUTEN-2-YL,, 2-PENTENE-2-YL OR 4-METHYL-2-PENTENE-2-YL. THE COMPOUNDS ARE BROAD SPECTRUM ANTIPARASITIC AGENTS HAVING UTILITY AS ANTHELMINTICS, ECTOPARASITICIDES, INSECTICIDES AND ACARICIDES. THE INVENTION ALSO PROVIDES A PROCESS FOR PRODUCING THE NOVEL AVERMECTIN AND MILBEMYCIN DERIVATIVES BY ADDING A CARBOXYLIC ACID OR DERIVATIVE THEREOF TO A FERMENTATION OF AN AVERMECTIN OR MILBEMYCIN PRODUCING ORGANISM.
MYPI87001126A 1985-07-27 1987-07-25 Antiparasitic agents and process for their preparation. MY101771A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB858518999A GB8518999D0 (en) 1985-07-27 1985-07-27 Antiparasitic agents
GB858520069A GB8520069D0 (en) 1985-08-09 1985-08-09 Anti-parasitic agents
GB868610063A GB8610063D0 (en) 1986-04-24 1986-04-24 Antiparasitic agents
GB868610862A GB8610862D0 (en) 1986-05-02 1986-05-02 Antiparasitic agents
EP86305604A EP0214731B1 (en) 1985-07-27 1986-07-22 Antiparasitic avermectin and milbemycin derivatives and process for their preparation

Publications (1)

Publication Number Publication Date
MY101771A true MY101771A (en) 1992-01-17

Family

ID=27513440

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI87001126A MY101771A (en) 1985-07-27 1987-07-25 Antiparasitic agents and process for their preparation.

Country Status (3)

Country Link
AT (1) ATE59652T1 (en)
CS (1) CS354391A3 (en)
MY (1) MY101771A (en)

Also Published As

Publication number Publication date
ATE59652T1 (en) 1991-01-15
CS354391A3 (en) 1992-08-12

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