ES8706714A1 - Procedimiento para la preparacion de derivados de 13beta-alquil-milbemicina - Google Patents

Procedimiento para la preparacion de derivados de 13beta-alquil-milbemicina

Info

Publication number
ES8706714A1
ES8706714A1 ES556598A ES556598A ES8706714A1 ES 8706714 A1 ES8706714 A1 ES 8706714A1 ES 556598 A ES556598 A ES 556598A ES 556598 A ES556598 A ES 556598A ES 8706714 A1 ES8706714 A1 ES 8706714A1
Authority
ES
Spain
Prior art keywords
beta
mylbemycin
derivatives
alkyl
combating animal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES556598A
Other languages
English (en)
Other versions
ES556598A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES556598A0 publication Critical patent/ES556598A0/es
Publication of ES8706714A1 publication Critical patent/ES8706714A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE 13 BETA-ALQUIL-MILBEMICINA, DE FORMULA GENERAL (I). CONSISTE EN TRATAR UN ESTER ALILICO DE FOMRULA GENERAL (II), EN LA QUE A REPRESENTA UN RADICAL; R REPRESENTA ALQUILO DE 1 A 10 ATOMOS DE CARBONO; R1 SIGNIFICA HIDROGENO O UN GRUPO DE SILILO; Y R2 REPRESENTA METILO, ETILO O ISOPROPILO, CON UN COMPUESTO DE TRIALQUILALUMINIO, DE FORMULA GENERAL (III). A CONTINUACION SE DISOCIA HIDROLITICAMENTE EL GRUPO DE SILILO, SIEMPRE QUE SE DESEEN COMPUESTOS DE 5-HIDROXILO LIBRES. DE APLICACION DE LA ELIMINACION DE PLAGAS DE ECTOPARASITOS Y ENDOPARASITOS, EN ANIMALES Y PLANTAS. *FORMULA*
ES556598A 1985-01-22 1986-06-25 Procedimiento para la preparacion de derivados de 13beta-alquil-milbemicina Expired ES8706714A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH27885 1985-01-22

Publications (2)

Publication Number Publication Date
ES556598A0 ES556598A0 (es) 1987-07-16
ES8706714A1 true ES8706714A1 (es) 1987-07-16

Family

ID=4183349

Family Applications (2)

Application Number Title Priority Date Filing Date
ES551069A Expired ES8706153A1 (es) 1985-01-22 1986-01-21 Procedimiento para la preparacion de derivados de 13beta-alquil-milbenicina
ES556598A Expired ES8706714A1 (es) 1985-01-22 1986-06-25 Procedimiento para la preparacion de derivados de 13beta-alquil-milbemicina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES551069A Expired ES8706153A1 (es) 1985-01-22 1986-01-21 Procedimiento para la preparacion de derivados de 13beta-alquil-milbenicina

Country Status (21)

Country Link
US (1) US4857509A (es)
EP (1) EP0189159B1 (es)
JP (1) JPH0759584B2 (es)
CN (1) CN86101035A (es)
AU (1) AU590535B2 (es)
DD (2) DD250458A5 (es)
DE (1) DE3685828D1 (es)
DK (1) DK29686A (es)
ES (2) ES8706153A1 (es)
FI (1) FI860233A (es)
GB (1) GB2169898B (es)
GR (1) GR860145B (es)
HU (1) HUT39568A (es)
IE (1) IE860178L (es)
IL (1) IL77650A (es)
MA (1) MA20614A1 (es)
NZ (1) NZ214879A (es)
PH (1) PH23773A (es)
PT (1) PT81875B (es)
ZA (1) ZA86437B (es)
ZW (1) ZW1386A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4587247A (en) * 1985-02-25 1986-05-06 Merck & Co., Inc. Substituted and unsubstituted 13-(alkoxy)methoxy derivatives of the avermectin aglycones, compositions and use
EP0235085A1 (de) * 1986-02-20 1987-09-02 Ciba-Geigy Ag 13-Beta-Zuckerderivate von Milbemycinen, deren Herstellung und Verwendung gegen Ekto-und Endoparasiten am Nutztier oder an der Nutzpflanze
NZ219467A (en) * 1986-03-07 1990-03-27 Ciba Geigy Ag 5-acyloxy 13b-alkyl milbemycins and parasiticidal compositions
EP0253378A3 (de) * 1986-07-18 1988-03-23 Ciba-Geigy Ag 13Beta-Alkyl-derivate von S541-Antibiotika zur Bekämpfung von Parasiten an Nutztieren und Pflanzen
US4855317A (en) * 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
EP0282456A3 (de) * 1987-03-13 1989-10-11 Ciba-Geigy Ag Milbemycin-Derivate zur Bekämpfung von Parasiten an Tieren
EP0285561A3 (de) * 1987-03-27 1989-10-25 Ciba-Geigy Ag Parasitizide und insektizide Milbemycin-Derivate
GB8804440D0 (en) * 1988-02-25 1988-03-23 Pfizer Ltd Antiparasitic agents
US4918097A (en) * 1988-03-11 1990-04-17 Ciba-Geigy Corporation Insecticides and parasiticides
DK227289A (da) * 1988-05-10 1989-11-11 American Cyanamid Co Makrolidforbindelser
GB8811036D0 (en) * 1988-05-10 1988-06-15 Glaxo Group Ltd Chemical compounds
GB8813150D0 (en) * 1988-06-03 1988-07-06 American Cyanamid Co Chemical compounds
US5055486A (en) * 1989-12-22 1991-10-08 American Cyanamid Company 13-alkyl-23-imino derivative of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
US5461168A (en) * 1992-09-01 1995-10-24 Sankyo Company, Limited Processes for the production of 13-ether derivatives of milbemycins, and intermediates therefor
JP4373080B2 (ja) * 2002-12-24 2009-11-25 三井化学アグロ株式会社 ミルベマイシン類の精製法
GB0302547D0 (en) * 2003-02-04 2003-03-12 Syngenta Participations Ag Avermectins and avermectin monosaccharide substituted in the 4'- and 4" position having pesticidal properties

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950360A (en) * 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
US4093629A (en) * 1977-04-11 1978-06-06 Merck & Co., Inc. Derivatives of antibiotic substance milbemycin and processes therefor
US4173571A (en) * 1977-12-19 1979-11-06 Merck & Co., Inc. 13-Halo and 13-deoxy derivatives of C-076 compounds
JPS5632481A (en) * 1979-08-23 1981-04-01 Sankyo Co Ltd Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent
US4427663A (en) * 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
US4582852A (en) * 1983-11-02 1986-04-15 Ciba-Geigy Corporation 14- and 15-hydroxy milbemycin derivatives for controlling plant and animal parasites
DK614084A (da) * 1983-12-30 1985-07-01 Ciba Geigy Ag Milbemycim-derivater samt deres fremstilling og anvendelse
EP0180539A1 (de) * 1984-09-18 1986-05-07 Ciba-Geigy Ag 13-Halo- und 13-Hydroximilbemycine
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof

Also Published As

Publication number Publication date
CN86101035A (zh) 1986-10-08
PT81875B (de) 1987-11-10
DK29686D0 (da) 1986-01-21
DE3685828D1 (de) 1992-08-06
GB2169898B (en) 1988-05-25
US4857509A (en) 1989-08-15
DK29686A (da) 1986-07-23
JPS61172883A (ja) 1986-08-04
ES551069A0 (es) 1987-06-01
JPH0759584B2 (ja) 1995-06-28
GB2169898A (en) 1986-07-23
NZ214879A (en) 1989-07-27
ES556598A0 (es) 1987-07-16
EP0189159A2 (de) 1986-07-30
EP0189159B1 (de) 1992-07-01
DD250458A5 (de) 1987-10-14
AU5256486A (en) 1986-07-31
MA20614A1 (fr) 1986-10-01
AU590535B2 (en) 1989-11-09
IL77650A (en) 1990-09-17
ZW1386A1 (en) 1986-09-03
PH23773A (en) 1989-11-03
GR860145B (en) 1986-05-16
FI860233A0 (fi) 1986-01-17
ES8706153A1 (es) 1987-06-01
ZA86437B (en) 1986-09-24
FI860233A (fi) 1986-07-23
PT81875A (de) 1986-02-01
HUT39568A (en) 1986-10-29
DD262661A5 (de) 1988-12-07
GB8601292D0 (en) 1986-02-26
IE860178L (en) 1986-07-22
EP0189159A3 (en) 1986-11-05

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