ES2002111A6 - Un procedimiento para preparar pirimido-(2,1-b)-benzotiazoles - Google Patents

Un procedimiento para preparar pirimido-(2,1-b)-benzotiazoles

Info

Publication number
ES2002111A6
ES2002111A6 ES8600714A ES8600714A ES2002111A6 ES 2002111 A6 ES2002111 A6 ES 2002111A6 ES 8600714 A ES8600714 A ES 8600714A ES 8600714 A ES8600714 A ES 8600714A ES 2002111 A6 ES2002111 A6 ES 2002111A6
Authority
ES
Spain
Prior art keywords
group
preparation
chained
branched
straight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600714A
Other languages
English (en)
Inventor
David Alun Rowlands
Saroop Singh Matharu
Peter Hairsine Hairsine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES2002111A6 publication Critical patent/ES2002111A6/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/26Radicals substituted by sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Saccharide Compounds (AREA)

Abstract

UN PROCEDIMIENTO PARA PREPARAR PIRIMIDO (2, 1-B) BENZOTIAZOLES DE FORMULA: DONDE R Y R3 REPRESENTAN HIDROGENO O ALQUILO O FORMAN CICLOALQUILO JUNTO CON EL CARBONO INTERMEDIO, R1 REPRESENTA ALCOXI Y R2 REPRESENTA HIDROGENO O UN RADICAL ORGANICO, EN EL QUE SE HACE REACCIONAR UN COMPUESTO DE FORMULA: DONDE R, R1 Y R3 SON COMO ANTES, CON UN COMPUESTO DE FORMULA: HR2CCFCCCO2R4 (III) DONDE R2 ES COMO ANTES Y R4 ES ALQUILO, TRAS LO CUAL EL COMPUESTO RESULTANTE SE AISLA CON TAL Y, OPCIONALMENTE, SE SALIFICA, O BIEN SE TRANSESTERIFICA CON UN ALCOHOL Y LUEGO SE AISLA Y, OPCIONALMENTE, SE SALIFICA. LOS COMPUESTOS OBTENIDOS SON ESPECIALMENTE UTILES COMO AGENTES ANTIALERGICOS.
ES8600714A 1985-07-31 1986-07-30 Un procedimiento para preparar pirimido-(2,1-b)-benzotiazoles Expired ES2002111A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858519261A GB8519261D0 (en) 1985-07-31 1985-07-31 Chemical compounds

Publications (1)

Publication Number Publication Date
ES2002111A6 true ES2002111A6 (es) 1988-07-16

Family

ID=10583097

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600714A Expired ES2002111A6 (es) 1985-07-31 1986-07-30 Un procedimiento para preparar pirimido-(2,1-b)-benzotiazoles

Country Status (17)

Country Link
EP (1) EP0211759B1 (es)
JP (1) JPS6229592A (es)
KR (1) KR870001221A (es)
AT (1) ATE62689T1 (es)
AU (1) AU586010B2 (es)
CA (1) CA1286290C (es)
DE (1) DE3678764D1 (es)
DK (1) DK361286A (es)
ES (1) ES2002111A6 (es)
FI (1) FI863118A (es)
GB (2) GB8519261D0 (es)
GR (1) GR862015B (es)
HU (1) HU194895B (es)
NZ (1) NZ217026A (es)
PT (1) PT83099B (es)
SU (1) SU1544191A3 (es)
ZA (1) ZA865170B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403739D0 (en) * 1984-02-13 1984-03-14 Roussel Lab Ltd Chemical compounds
GB8522186D0 (en) * 1985-09-06 1985-10-09 Erba Farmitalia Cycloalkyl-substituted 4-aminophenyl derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3919201A (en) * 1970-09-30 1975-11-11 Lilly Industries Ltd 2-({62 -Aminoacryloyl)iminobenzothiazolines
DE2810863A1 (de) * 1978-03-13 1979-09-27 Boehringer Mannheim Gmbh 1-oxo-1h-pyrimido eckige klammer auf 6,1-b eckige klammer zu benzthiazol-derivate und verfahren zu ihrer herstellung
GB8403739D0 (en) * 1984-02-13 1984-03-14 Roussel Lab Ltd Chemical compounds

Also Published As

Publication number Publication date
NZ217026A (en) 1989-02-24
CA1286290C (en) 1991-07-16
ZA865170B (en) 1987-09-30
AU586010B2 (en) 1989-06-29
DE3678764D1 (de) 1991-05-23
KR870001221A (ko) 1987-03-12
EP0211759A3 (en) 1988-03-30
FI863118A0 (fi) 1986-07-30
GB8618641D0 (en) 1986-09-10
FI863118A (fi) 1987-02-01
PT83099A (en) 1986-08-01
GB8519261D0 (en) 1985-09-04
GR862015B (en) 1986-12-23
GB2178429A (en) 1987-02-11
EP0211759A2 (fr) 1987-02-25
SU1544191A3 (ru) 1990-02-15
ATE62689T1 (de) 1991-05-15
PT83099B (pt) 1988-11-30
EP0211759B1 (fr) 1991-04-17
HUT42776A (en) 1987-08-28
DK361286A (da) 1987-02-01
JPS6229592A (ja) 1987-02-07
GB2178429B (en) 1989-09-13
HU194895B (en) 1988-03-28
AU6068786A (en) 1987-02-05
DK361286D0 (da) 1986-07-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000202