ES8406431A1 - Procedimiento para preparar derivados de pleuromutilina - Google Patents

Procedimiento para preparar derivados de pleuromutilina

Info

Publication number
ES8406431A1
ES8406431A1 ES521847A ES521847A ES8406431A1 ES 8406431 A1 ES8406431 A1 ES 8406431A1 ES 521847 A ES521847 A ES 521847A ES 521847 A ES521847 A ES 521847A ES 8406431 A1 ES8406431 A1 ES 8406431A1
Authority
ES
Spain
Prior art keywords
alkylamino
unsubstituted
amino
substituted
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES521847A
Other languages
English (en)
Other versions
ES521847A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES521847A0 publication Critical patent/ES521847A0/es
Publication of ES8406431A1 publication Critical patent/ES8406431A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE PLEUROMUTILINA Y DE SUS SALES DE ADICION DE ACIDOS O DE SAL CUATERNARIA, DE FORMULA (I), EN LA QUE R1 ES ETILO O VINILO, R3 Y R4 SON HIDROGENO O ALQUILO INFERIOR Y R2 PUEDE SER VARIOS RADICALES.CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN LAS QUE R5 PUEDE SER VARIOS RADICALES Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), EN UN DISOLVENTE INERTE, A UNA TEMPERATURA ENTRE 25JC Y 55JC.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANTIBIOTICOS.
ES521847A 1982-04-28 1983-04-26 Procedimiento para preparar derivados de pleuromutilina Expired ES8406431A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT165182 1982-04-28
AT427082 1982-11-24

Publications (2)

Publication Number Publication Date
ES521847A0 ES521847A0 (es) 1984-08-01
ES8406431A1 true ES8406431A1 (es) 1984-08-01

Family

ID=25596422

Family Applications (1)

Application Number Title Priority Date Filing Date
ES521847A Expired ES8406431A1 (es) 1982-04-28 1983-04-26 Procedimiento para preparar derivados de pleuromutilina

Country Status (12)

Country Link
AU (1) AU1393783A (es)
DE (1) DE3314479A1 (es)
DK (1) DK185683A (es)
ES (1) ES8406431A1 (es)
FI (1) FI831367L (es)
FR (1) FR2526019A1 (es)
GB (1) GB2121035A (es)
IL (1) IL68508A0 (es)
IT (1) IT1197634B (es)
NL (1) NL8301448A (es)
PT (1) PT76598B (es)
SE (1) SE8302345L (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3560511D1 (en) * 1984-02-17 1987-10-01 Sandoz Ag Pleuromutilin derivatives, process for their preparation and their use
HU208115B (en) * 1989-10-03 1993-08-30 Biochemie Gmbh New process for producting pleuromutilin derivatives
GB0017031D0 (en) * 2000-07-11 2000-08-30 Biochemie Gmbh Antimicrobials
GB0218578D0 (en) 2002-08-09 2002-09-18 Glaxo Group Ltd Novel method
CN104961666B (zh) * 2014-07-08 2017-04-12 南通大学 2‑巯基乙酰胺类截短侧耳素衍生物及制备方法与医药用途
CN104447450B (zh) * 2014-07-08 2016-09-28 南通大学 半胱氨酸酰胺类截短侧耳素衍生物及制备方法与医药用途
CN109384698B (zh) * 2017-08-04 2022-07-08 保定加合精细化工有限公司 一种双萜烯类畜禽用抗生素的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT301752B (de) * 1969-07-21 1972-09-25 Biochemie Gmbh Verfahren zur Herstellung neuer Pleuromutilin-Derivate
US3919290A (en) * 1972-10-03 1975-11-11 Sandoz Ltd Substituted 14-desoxy-mutilins
CA1077056A (en) * 1975-09-30 1980-05-06 Friedrich Dursch Derivatives of pleuromutilin and compositions
DE2823712A1 (de) * 1978-05-31 1979-12-06 Sandoz Ag Verfahren zur herstellung von pleuromutilin-derivaten

Also Published As

Publication number Publication date
PT76598B (en) 1986-01-24
FR2526019A1 (fr) 1983-11-04
PT76598A (en) 1983-05-01
GB8311194D0 (en) 1983-06-02
DK185683D0 (da) 1983-04-26
FI831367A0 (fi) 1983-04-21
DE3314479A1 (de) 1983-11-03
IT1197634B (it) 1988-12-06
FI831367L (fi) 1983-10-29
FR2526019B1 (es) 1985-04-26
IL68508A0 (en) 1983-07-31
SE8302345L (sv) 1983-10-29
AU1393783A (en) 1983-11-03
NL8301448A (nl) 1983-11-16
DK185683A (da) 1983-10-29
ES521847A0 (es) 1984-08-01
GB2121035A (en) 1983-12-14
IT8348162A0 (it) 1983-04-27
SE8302345D0 (sv) 1983-04-26

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000201