ATA245286A - Verfahren zur herstellung neuer carbapenem-antibiotika - Google Patents

Verfahren zur herstellung neuer carbapenem-antibiotika

Info

Publication number
ATA245286A
ATA245286A AT862452A AT245286A ATA245286A AT A245286 A ATA245286 A AT A245286A AT 862452 A AT862452 A AT 862452A AT 245286 A AT245286 A AT 245286A AT A245286 A ATA245286 A AT A245286A
Authority
AT
Austria
Prior art keywords
producing new
carbapenem antibiotics
new carbapenem
antibiotics
producing
Prior art date
Application number
AT862452A
Other languages
English (en)
Other versions
AT396472B (de
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of ATA245286A publication Critical patent/ATA245286A/de
Application granted granted Critical
Publication of AT396472B publication Critical patent/AT396472B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT0245286A 1985-09-11 1986-09-11 Verfahren zur herstellung neuer carbapenem-antibiotika AT396472B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/774,628 US4665169A (en) 1985-09-11 1985-09-11 Carbapenem antibiotics

Publications (2)

Publication Number Publication Date
ATA245286A true ATA245286A (de) 1993-01-15
AT396472B AT396472B (de) 1993-09-27

Family

ID=25101800

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0245286A AT396472B (de) 1985-09-11 1986-09-11 Verfahren zur herstellung neuer carbapenem-antibiotika

Country Status (31)

Country Link
US (1) US4665169A (de)
JP (1) JPS6261980A (de)
KR (1) KR910006807B1 (de)
CN (1) CN1015261B (de)
AR (1) AR242577A1 (de)
AT (1) AT396472B (de)
AU (1) AU596990B2 (de)
BE (1) BE905415A (de)
CH (1) CH669381A5 (de)
CS (1) CS259892B2 (de)
DD (1) DD252605A1 (de)
DE (1) DE3630857C2 (de)
DK (1) DK433586A (de)
ES (1) ES2002303A6 (de)
FI (1) FI81803C (de)
FR (1) FR2587704B1 (de)
GB (1) GB2180238B (de)
GR (1) GR862313B (de)
HU (1) HU198491B (de)
IL (1) IL79969A0 (de)
IT (1) IT1207578B (de)
LU (1) LU86575A1 (de)
MY (1) MY102957A (de)
NL (1) NL8602282A (de)
NZ (1) NZ217519A (de)
PT (1) PT83361B (de)
SE (1) SE469630B (de)
SU (1) SU1480764A3 (de)
YU (1) YU45800B (de)
ZA (1) ZA866638B (de)
ZW (1) ZW16186A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5321020A (en) * 1989-03-28 1994-06-14 Pfizer Inc. Antibacterial 2-carbapenem derivatives
FI914558A7 (fi) * 1989-03-28 1991-09-27 Pfizer Bakteerinvastaisia 2-karbapeneemijohdannaisia
US5602118A (en) * 1993-03-16 1997-02-11 American Cyanamid Company 2-thiosubstituted carbapenems
RU2714730C1 (ru) 2019-04-11 2020-02-19 Общество с ограниченной ответственностью "КС-ТЕХНОЛОГИИ" Конусная инерционная дробилка с опорным подшипником скольжения

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
US4235920A (en) * 1975-11-21 1980-11-25 Merck & Co., Inc. N-Alkylated derivatives of thienamycin
AU4061378A (en) * 1977-10-19 1980-04-17 Merck & Co., Inc. 1-azabicyclo (3.2.0) hept-2-enes
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
US4232036A (en) * 1978-10-24 1980-11-04 Merck & Co., Inc. 6-, 1- and 2-Substituted-1-carbadethiapen-2-em-3-carboxylic acids
IE51861B1 (en) * 1978-10-24 1987-04-15 Merck & Co Inc 6-,1-and 2-substituted-1-carbapen-2-em-3-carboxylic acids,processes for the preparation of such compounds and pharmaceutical compositions comprising such compounds
EP0082133A3 (en) * 1979-04-19 1983-07-20 Merck & Co. Inc. A process for preparing intermediates useful for preparing 2-substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids
US4376774A (en) * 1979-05-29 1983-03-15 Merck & Co., Inc. Antibiotic N-heterocyclyl thienamycin
US4309346A (en) * 1980-03-27 1982-01-05 Merck & Co., Inc. Process for the preparation of 1-carbapenems and intermediates via trithioorthoacetates
IE52147B1 (en) * 1980-03-27 1987-07-08 Merck & Co Inc 4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
DE3169321D1 (en) * 1980-03-27 1985-04-25 Merck & Co Inc Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals
EP0038869A1 (de) * 1980-04-30 1981-11-04 Merck & Co. Inc. Verfahren zur Herstellung von 1-Carbapenemen und Zwischenprodukte für ihre Herstellung
JPS56161393A (en) * 1980-05-16 1981-12-11 Sanraku Inc Beta-lactam compound
CA1198440A (en) * 1982-04-08 1985-12-24 Choung U. Kim Carbapenem antibiotics
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
FI832619A7 (fi) * 1982-07-26 1984-01-27 Sandoz Ag Fluoralkylerade karbapenemderivat
NZ205626A (en) * 1982-09-28 1986-12-05 Bristol Myers Co Carbapenem antibiotics
AR241016A1 (es) * 1983-03-08 1991-04-30 Bristol Myeres Squibb Company "derivados de aminotiol cuaternario, procedimiento para prepararlos y procedimiento para preparar compuestos de carbapenem a partir de dichos derivados".
JPS60202886A (ja) * 1984-03-27 1985-10-14 Sankyo Co Ltd 1―置換カルバペネム―3―カルボン酸誘導体

Also Published As

Publication number Publication date
AU6234886A (en) 1987-03-12
BE905415A (fr) 1987-03-10
IT1207578B (it) 1989-05-25
FI863609A0 (fi) 1986-09-08
SE469630B (sv) 1993-08-09
ZW16186A1 (en) 1988-03-30
KR870003110A (ko) 1987-04-15
AR242577A1 (es) 1993-04-30
GB2180238B (en) 1989-09-06
DD252605A1 (de) 1987-12-23
CS259892B2 (en) 1988-11-15
DK433586A (da) 1987-03-12
CS656786A2 (en) 1988-03-15
PT83361B (pt) 1989-05-12
FI863609L (fi) 1987-03-12
KR910006807B1 (ko) 1991-09-02
FR2587704A1 (fr) 1987-03-27
SE8603798L (sv) 1987-03-12
NL8602282A (nl) 1987-04-01
AU596990B2 (en) 1990-05-24
GB2180238A (en) 1987-03-25
DE3630857C2 (de) 1994-04-07
YU158586A (en) 1988-02-29
DK433586D0 (da) 1986-09-10
CN1015261B (zh) 1992-01-01
GR862313B (en) 1987-01-12
JPS6261980A (ja) 1987-03-18
NZ217519A (en) 1990-07-26
ES2002303A6 (es) 1988-08-01
US4665169A (en) 1987-05-12
FI81803C (fi) 1990-12-10
IL79969A0 (en) 1986-12-31
SU1480764A3 (ru) 1989-05-15
PT83361A (en) 1986-10-01
HU198491B (en) 1989-10-30
ZA866638B (en) 1987-05-27
YU45800B (sh) 1992-07-20
FR2587704B1 (fr) 1989-02-24
GB8621759D0 (en) 1986-10-15
FI81803B (fi) 1990-08-31
LU86575A1 (fr) 1987-04-02
IT8621666A0 (it) 1986-09-10
DE3630857A1 (de) 1987-03-19
CH669381A5 (de) 1989-03-15
MY102957A (en) 1993-03-31
HUT42487A (en) 1987-07-28
AT396472B (de) 1993-09-27
SE8603798D0 (sv) 1986-09-10
CN86105933A (zh) 1987-05-20

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