FR2587704B1 - Antibiotiques a base de carbapenem - Google Patents

Antibiotiques a base de carbapenem

Info

Publication number
FR2587704B1
FR2587704B1 FR868612540A FR8612540A FR2587704B1 FR 2587704 B1 FR2587704 B1 FR 2587704B1 FR 868612540 A FR868612540 A FR 868612540A FR 8612540 A FR8612540 A FR 8612540A FR 2587704 B1 FR2587704 B1 FR 2587704B1
Authority
FR
France
Prior art keywords
carbapenem
based antibiotics
antibiotics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR868612540A
Other languages
English (en)
Other versions
FR2587704A1 (fr
Inventor
Alain Martel
Carol Bachand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FR2587704A1 publication Critical patent/FR2587704A1/fr
Application granted granted Critical
Publication of FR2587704B1 publication Critical patent/FR2587704B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
FR868612540A 1985-09-11 1986-09-08 Antibiotiques a base de carbapenem Expired FR2587704B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/774,628 US4665169A (en) 1985-09-11 1985-09-11 Carbapenem antibiotics

Publications (2)

Publication Number Publication Date
FR2587704A1 FR2587704A1 (fr) 1987-03-27
FR2587704B1 true FR2587704B1 (fr) 1989-02-24

Family

ID=25101800

Family Applications (1)

Application Number Title Priority Date Filing Date
FR868612540A Expired FR2587704B1 (fr) 1985-09-11 1986-09-08 Antibiotiques a base de carbapenem

Country Status (31)

Country Link
US (1) US4665169A (fr)
JP (1) JPS6261980A (fr)
KR (1) KR910006807B1 (fr)
CN (1) CN1015261B (fr)
AR (1) AR242577A1 (fr)
AT (1) AT396472B (fr)
AU (1) AU596990B2 (fr)
BE (1) BE905415A (fr)
CH (1) CH669381A5 (fr)
CS (1) CS259892B2 (fr)
DD (1) DD252605A1 (fr)
DE (1) DE3630857C2 (fr)
DK (1) DK433586A (fr)
ES (1) ES2002303A6 (fr)
FI (1) FI81803C (fr)
FR (1) FR2587704B1 (fr)
GB (1) GB2180238B (fr)
GR (1) GR862313B (fr)
HU (1) HU198491B (fr)
IL (1) IL79969A0 (fr)
IT (1) IT1207578B (fr)
LU (1) LU86575A1 (fr)
MY (1) MY102957A (fr)
NL (1) NL8602282A (fr)
NZ (1) NZ217519A (fr)
PT (1) PT83361B (fr)
SE (1) SE469630B (fr)
SU (1) SU1480764A3 (fr)
YU (1) YU45800B (fr)
ZA (1) ZA866638B (fr)
ZW (1) ZW16186A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5321020A (en) * 1989-03-28 1994-06-14 Pfizer Inc. Antibacterial 2-carbapenem derivatives
MX20084A (es) * 1989-03-28 1993-03-01 Pfizer Derivados de 2 -carbapenem antibacterianos
US5602118A (en) * 1993-03-16 1997-02-11 American Cyanamid Company 2-thiosubstituted carbapenems
RU2714730C1 (ru) 2019-04-11 2020-02-19 Общество с ограниченной ответственностью "КС-ТЕХНОЛОГИИ" Конусная инерционная дробилка с опорным подшипником скольжения

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
US4235920A (en) * 1975-11-21 1980-11-25 Merck & Co., Inc. N-Alkylated derivatives of thienamycin
AU4061378A (en) * 1977-10-19 1980-04-17 Merck & Co., Inc. 1-azabicyclo (3.2.0) hept-2-enes
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
DK446179A (da) * 1978-10-24 1980-05-29 Merck & Co Inc Fremgangsmaade til fremstilling af substituerede 1-carbadethiapen-2-em-3-carboxylsyrer
US4232036A (en) * 1978-10-24 1980-11-04 Merck & Co., Inc. 6-, 1- and 2-Substituted-1-carbadethiapen-2-em-3-carboxylic acids
EP0017992A1 (fr) * 1979-04-19 1980-10-29 Merck & Co. Inc. Acides 1-carbadéthiapén-2-èm-carboxyliques substitués en position 2 et 6, procédés pour les préparer, compositions pharmaceutiques antibiotiques les contenant et procédé pour préparer des intermédiaires
US4376774A (en) * 1979-05-29 1983-03-15 Merck & Co., Inc. Antibiotic N-heterocyclyl thienamycin
US4309346A (en) * 1980-03-27 1982-01-05 Merck & Co., Inc. Process for the preparation of 1-carbapenems and intermediates via trithioorthoacetates
EP0037082B1 (fr) * 1980-03-27 1985-03-20 Merck & Co. Inc. Procédé de préparation de composés du type 1-carbapénème et produits intermédiaires via dithioacétals substitués par des groupes silyle
IE52147B1 (en) * 1980-03-27 1987-07-08 Merck & Co Inc 4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
EP0038869A1 (fr) * 1980-04-30 1981-11-04 Merck & Co. Inc. Procédé de préparation de 1-carbapénèmes et intermédiaires pour leur préparation
JPS56161393A (en) * 1980-05-16 1981-12-11 Sanraku Inc Beta-lactam compound
CA1198440A (fr) * 1982-04-08 1985-12-24 Choung U. Kim Carbapenem antibiotiques
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
FI832619A (fi) * 1982-07-26 1984-01-27 Sandoz Ag Fluoralkylerade karbapenemderivat
NZ205626A (en) * 1982-09-28 1986-12-05 Bristol Myers Co Carbapenem antibiotics
DK140584A (da) * 1983-03-08 1984-09-09 Bristol Myers Co Fremgangsmaade til fremstilling af carbapenemderivater
JPS60202886A (ja) * 1984-03-27 1985-10-14 Sankyo Co Ltd １―置換カルバペネム―３―カルボン酸誘導体

Also Published As

Publication number Publication date
YU45800B (sh) 1992-07-20
SE8603798D0 (sv) 1986-09-10
BE905415A (fr) 1987-03-10
KR870003110A (ko) 1987-04-15
DK433586A (da) 1987-03-12
CH669381A5 (fr) 1989-03-15
MY102957A (en) 1993-03-31
SE8603798L (sv) 1987-03-12
LU86575A1 (fr) 1987-04-02
DD252605A1 (de) 1987-12-23
FI863609A0 (fi) 1986-09-08
ES2002303A6 (es) 1988-08-01
SE469630B (sv) 1993-08-09
GB2180238A (en) 1987-03-25
ATA245286A (de) 1993-01-15
GR862313B (en) 1987-01-12
AU596990B2 (en) 1990-05-24
HUT42487A (en) 1987-07-28
YU158586A (en) 1988-02-29
PT83361B (pt) 1989-05-12
FI81803C (fi) 1990-12-10
IL79969A0 (en) 1986-12-31
DK433586D0 (da) 1986-09-10
KR910006807B1 (ko) 1991-09-02
IT1207578B (it) 1989-05-25
CS259892B2 (en) 1988-11-15
DE3630857C2 (de) 1994-04-07
US4665169A (en) 1987-05-12
ZW16186A1 (en) 1988-03-30
AT396472B (de) 1993-09-27
AR242577A1 (es) 1993-04-30
GB2180238B (en) 1989-09-06
DE3630857A1 (de) 1987-03-19
GB8621759D0 (en) 1986-10-15
CS656786A2 (en) 1988-03-15
FR2587704A1 (fr) 1987-03-27
SU1480764A3 (ru) 1989-05-15
HU198491B (en) 1989-10-30
FI81803B (fi) 1990-08-31
NZ217519A (en) 1990-07-26
CN86105933A (zh) 1987-05-20
CN1015261B (zh) 1992-01-01
ZA866638B (en) 1987-05-27
PT83361A (en) 1986-10-01
NL8602282A (nl) 1987-04-01
AU6234886A (en) 1987-03-12
IT8621666A0 (it) 1986-09-10
JPS6261980A (ja) 1987-03-18
FI863609A (fi) 1987-03-12

Similar Documents

Publication Publication Date Title
DK418085A (da) Antibiotika
DK100886A (da) Antibiotiske clathrater
FR2577138B1 (fr) Immuno-regulateur a base de l-carnosine
ZA862987B (en) Carbapenem antibiotics
DE3665304D1 (de) Obelmycin a
FR2577645B1 (fr) Transmission a vis
SG109692G (en) Antibiotics
FR2587704B1 (fr) Antibiotiques a base de carbapenem
GB2183237B (en) Carbapenem antibiotics
IT1188650B (it) Urogastrone
BR8605418A (pt) Pneumatico
DE3688066T2 (de) 1-carbacephalosporin-antibiotika.
BR8601585A (pt) Parte de lata rasgavel
FR2580195B1 (fr) Selecteur pneumatique
SE8503781D0 (sv) A novel morpholinoenantiomer
ES546266A0 (es) Un nuevo antibiotico de antraciclina
IT1185350B (it) Lampada a stelo
BR8502837A (pt) Pneumatico
BR8502755A (pt) Pneumatico
DK239289D0 (da) Antibioticum
KR870006720U (ko) 포대 봉함구
KR860013284U (ko) 포대용 판지
KR860011373U (ko) 다기함 겸용상
GB8510628D0 (en) Antibiotics
DK577286D0 (da) Cephalosporinderivater

Legal Events

Date Code Title Description
ST Notification of lapse