DD252605A1 - Verfahren zur herstellung von carbapenem-antibiotika - Google Patents

Verfahren zur herstellung von carbapenem-antibiotika

Info

Publication number
DD252605A1
DD252605A1 DD86294267A DD29426786A DD252605A1 DD 252605 A1 DD252605 A1 DD 252605A1 DD 86294267 A DD86294267 A DD 86294267A DD 29426786 A DD29426786 A DD 29426786A DD 252605 A1 DD252605 A1 DD 252605A1
Authority
DD
German Democratic Republic
Prior art keywords
preparation
carbapenem antibiotics
carbapenem
antibiotics
Prior art date
Application number
DD86294267A
Other languages
English (en)
Inventor
Alain Martel
Carol Bachand
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DD252605A1 publication Critical patent/DD252605A1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
DD86294267A 1985-09-11 1986-09-09 Verfahren zur herstellung von carbapenem-antibiotika DD252605A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/774,628 US4665169A (en) 1985-09-11 1985-09-11 Carbapenem antibiotics

Publications (1)

Publication Number Publication Date
DD252605A1 true DD252605A1 (de) 1987-12-23

Family

ID=25101800

Family Applications (1)

Application Number Title Priority Date Filing Date
DD86294267A DD252605A1 (de) 1985-09-11 1986-09-09 Verfahren zur herstellung von carbapenem-antibiotika

Country Status (31)

Country Link
US (1) US4665169A (de)
JP (1) JPS6261980A (de)
KR (1) KR910006807B1 (de)
CN (1) CN1015261B (de)
AR (1) AR242577A1 (de)
AT (1) AT396472B (de)
AU (1) AU596990B2 (de)
BE (1) BE905415A (de)
CH (1) CH669381A5 (de)
CS (1) CS259892B2 (de)
DD (1) DD252605A1 (de)
DE (1) DE3630857C2 (de)
DK (1) DK433586A (de)
ES (1) ES2002303A6 (de)
FI (1) FI81803C (de)
FR (1) FR2587704B1 (de)
GB (1) GB2180238B (de)
GR (1) GR862313B (de)
HU (1) HU198491B (de)
IL (1) IL79969A0 (de)
IT (1) IT1207578B (de)
LU (1) LU86575A1 (de)
MY (1) MY102957A (de)
NL (1) NL8602282A (de)
NZ (1) NZ217519A (de)
PT (1) PT83361B (de)
SE (1) SE469630B (de)
SU (1) SU1480764A3 (de)
YU (1) YU45800B (de)
ZA (1) ZA866638B (de)
ZW (1) ZW16186A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5321020A (en) * 1989-03-28 1994-06-14 Pfizer Inc. Antibacterial 2-carbapenem derivatives
MX20084A (es) * 1989-03-28 1993-03-01 Pfizer Derivados de 2 -carbapenem antibacterianos
US5602118A (en) * 1993-03-16 1997-02-11 American Cyanamid Company 2-thiosubstituted carbapenems
RU2714730C1 (ru) 2019-04-11 2020-02-19 Общество с ограниченной ответственностью "КС-ТЕХНОЛОГИИ" Конусная инерционная дробилка с опорным подшипником скольжения

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
US4235920A (en) * 1975-11-21 1980-11-25 Merck & Co., Inc. N-Alkylated derivatives of thienamycin
AU4061378A (en) * 1977-10-19 1980-04-17 Merck & Co., Inc. 1-azabicyclo (3.2.0) hept-2-enes
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
DK446179A (da) * 1978-10-24 1980-05-29 Merck & Co Inc Fremgangsmaade til fremstilling af substituerede 1-carbadethiapen-2-em-3-carboxylsyrer
US4232036A (en) * 1978-10-24 1980-11-04 Merck & Co., Inc. 6-, 1- and 2-Substituted-1-carbadethiapen-2-em-3-carboxylic acids
EP0017992A1 (de) * 1979-04-19 1980-10-29 Merck & Co. Inc. 2-Substituierte-6-substituierte-1-Carbadethiapen-2-em-3-carbonsäuren, Verfahren zu ihrer Herstellung, sie enthaltende antibiotische pharmazeutische Zusammensetzungen und Verfahren zur Herstellung von Zwischenprodukten
US4376774A (en) * 1979-05-29 1983-03-15 Merck & Co., Inc. Antibiotic N-heterocyclyl thienamycin
US4309346A (en) * 1980-03-27 1982-01-05 Merck & Co., Inc. Process for the preparation of 1-carbapenems and intermediates via trithioorthoacetates
EP0037082B1 (de) * 1980-03-27 1985-03-20 Merck & Co. Inc. Verfahren zur Herstellung von 1-Carbapenem-Derivaten und von Zwischenprodukten via silyl-substituierter Dithioacetale
IE52147B1 (en) * 1980-03-27 1987-07-08 Merck & Co Inc 4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
EP0038869A1 (de) * 1980-04-30 1981-11-04 Merck & Co. Inc. Verfahren zur Herstellung von 1-Carbapenemen und Zwischenprodukte für ihre Herstellung
JPS56161393A (en) * 1980-05-16 1981-12-11 Sanraku Inc Beta-lactam compound
CA1198440A (en) * 1982-04-08 1985-12-24 Choung U. Kim Carbapenem antibiotics
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
FI832619A (fi) * 1982-07-26 1984-01-27 Sandoz Ag Fluoralkylerade karbapenemderivat
NZ205626A (en) * 1982-09-28 1986-12-05 Bristol Myers Co Carbapenem antibiotics
DK140584A (da) * 1983-03-08 1984-09-09 Bristol Myers Co Fremgangsmaade til fremstilling af carbapenemderivater
JPS60202886A (ja) * 1984-03-27 1985-10-14 Sankyo Co Ltd 1―置換カルバペネム―3―カルボン酸誘導体

Also Published As

Publication number Publication date
YU45800B (sh) 1992-07-20
SE8603798D0 (sv) 1986-09-10
BE905415A (fr) 1987-03-10
KR870003110A (ko) 1987-04-15
DK433586A (da) 1987-03-12
CH669381A5 (de) 1989-03-15
MY102957A (en) 1993-03-31
SE8603798L (sv) 1987-03-12
LU86575A1 (fr) 1987-04-02
FI863609A0 (fi) 1986-09-08
ES2002303A6 (es) 1988-08-01
SE469630B (sv) 1993-08-09
GB2180238A (en) 1987-03-25
ATA245286A (de) 1993-01-15
GR862313B (en) 1987-01-12
AU596990B2 (en) 1990-05-24
HUT42487A (en) 1987-07-28
YU158586A (en) 1988-02-29
PT83361B (pt) 1989-05-12
FI81803C (fi) 1990-12-10
IL79969A0 (en) 1986-12-31
DK433586D0 (da) 1986-09-10
KR910006807B1 (ko) 1991-09-02
IT1207578B (it) 1989-05-25
CS259892B2 (en) 1988-11-15
DE3630857C2 (de) 1994-04-07
US4665169A (en) 1987-05-12
ZW16186A1 (en) 1988-03-30
AT396472B (de) 1993-09-27
AR242577A1 (es) 1993-04-30
GB2180238B (en) 1989-09-06
DE3630857A1 (de) 1987-03-19
GB8621759D0 (en) 1986-10-15
FR2587704B1 (fr) 1989-02-24
CS656786A2 (en) 1988-03-15
FR2587704A1 (fr) 1987-03-27
SU1480764A3 (ru) 1989-05-15
HU198491B (en) 1989-10-30
FI81803B (fi) 1990-08-31
NZ217519A (en) 1990-07-26
CN86105933A (zh) 1987-05-20
CN1015261B (zh) 1992-01-01
ZA866638B (en) 1987-05-27
PT83361A (en) 1986-10-01
NL8602282A (nl) 1987-04-01
AU6234886A (en) 1987-03-12
IT8621666A0 (it) 1986-09-10
JPS6261980A (ja) 1987-03-18
FI863609A (fi) 1987-03-12

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Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee