SE8603798L - Karbapenem-antibiotika - Google Patents

Karbapenem-antibiotika

Info

Publication number
SE8603798L
SE8603798L SE8603798A SE8603798A SE8603798L SE 8603798 L SE8603798 L SE 8603798L SE 8603798 A SE8603798 A SE 8603798A SE 8603798 A SE8603798 A SE 8603798A SE 8603798 L SE8603798 L SE 8603798L
Authority
SE
Sweden
Prior art keywords
alkyl
carbapenem antibiotics
moiety
cyanomethyl
propargyl
Prior art date
Application number
SE8603798A
Other languages
English (en)
Other versions
SE8603798D0 (sv
SE469630B (sv
Inventor
A Martel
C Bachand
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE8603798D0 publication Critical patent/SE8603798D0/sv
Publication of SE8603798L publication Critical patent/SE8603798L/sv
Publication of SE469630B publication Critical patent/SE469630B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE8603798A 1985-09-11 1986-09-10 Karbapenem-antibiotika SE469630B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/774,628 US4665169A (en) 1985-09-11 1985-09-11 Carbapenem antibiotics

Publications (3)

Publication Number Publication Date
SE8603798D0 SE8603798D0 (sv) 1986-09-10
SE8603798L true SE8603798L (sv) 1987-03-12
SE469630B SE469630B (sv) 1993-08-09

Family

ID=25101800

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8603798A SE469630B (sv) 1985-09-11 1986-09-10 Karbapenem-antibiotika

Country Status (31)

Country Link
US (1) US4665169A (sv)
JP (1) JPS6261980A (sv)
KR (1) KR910006807B1 (sv)
CN (1) CN1015261B (sv)
AR (1) AR242577A1 (sv)
AT (1) AT396472B (sv)
AU (1) AU596990B2 (sv)
BE (1) BE905415A (sv)
CH (1) CH669381A5 (sv)
CS (1) CS259892B2 (sv)
DD (1) DD252605A1 (sv)
DE (1) DE3630857C2 (sv)
DK (1) DK433586A (sv)
ES (1) ES2002303A6 (sv)
FI (1) FI81803C (sv)
FR (1) FR2587704B1 (sv)
GB (1) GB2180238B (sv)
GR (1) GR862313B (sv)
HU (1) HU198491B (sv)
IL (1) IL79969A0 (sv)
IT (1) IT1207578B (sv)
LU (1) LU86575A1 (sv)
MY (1) MY102957A (sv)
NL (1) NL8602282A (sv)
NZ (1) NZ217519A (sv)
PT (1) PT83361B (sv)
SE (1) SE469630B (sv)
SU (1) SU1480764A3 (sv)
YU (1) YU45800B (sv)
ZA (1) ZA866638B (sv)
ZW (1) ZW16186A1 (sv)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU209817B (en) * 1989-03-28 1994-11-28 Pfizer Process for the production of antibacterial 2-carbapenem derivatives
US5321020A (en) * 1989-03-28 1994-06-14 Pfizer Inc. Antibacterial 2-carbapenem derivatives
US5602118A (en) * 1993-03-16 1997-02-11 American Cyanamid Company 2-thiosubstituted carbapenems
RU2714730C1 (ru) 2019-04-11 2020-02-19 Общество с ограниченной ответственностью "КС-ТЕХНОЛОГИИ" Конусная инерционная дробилка с опорным подшипником скольжения

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
US4235920A (en) * 1975-11-21 1980-11-25 Merck & Co., Inc. N-Alkylated derivatives of thienamycin
AU4061378A (en) * 1977-10-19 1980-04-17 Merck & Co., Inc. 1-azabicyclo (3.2.0) hept-2-enes
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
EP0010317B1 (en) * 1978-10-24 1983-12-21 Merck & Co. Inc. 6-, 1- and 2-substituted-1-carbapen-2-em-3-carboxylic acids, processes for the preparation of such compounds and pharmaceutical composition comprising such compounds
US4232036A (en) * 1978-10-24 1980-11-04 Merck & Co., Inc. 6-, 1- and 2-Substituted-1-carbadethiapen-2-em-3-carboxylic acids
EP0017992A1 (en) * 1979-04-19 1980-10-29 Merck & Co. Inc. 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates
US4376774A (en) * 1979-05-29 1983-03-15 Merck & Co., Inc. Antibiotic N-heterocyclyl thienamycin
IE52147B1 (en) * 1980-03-27 1987-07-08 Merck & Co Inc 4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
EP0037082B1 (en) * 1980-03-27 1985-03-20 Merck & Co. Inc. Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals
US4309346A (en) * 1980-03-27 1982-01-05 Merck & Co., Inc. Process for the preparation of 1-carbapenems and intermediates via trithioorthoacetates
EP0038869A1 (en) * 1980-04-30 1981-11-04 Merck & Co. Inc. Process for the preparation of 1-carbapenems, and intermediates for their preparation
JPS56161393A (en) * 1980-05-16 1981-12-11 Sanraku Inc Beta-lactam compound
CA1198440A (en) * 1982-04-08 1985-12-24 Choung U. Kim Carbapenem antibiotics
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
FI832619A (fi) * 1982-07-26 1984-01-27 Sandoz Ag Fluoralkylerade karbapenemderivat
CA1269978A (en) * 1982-09-28 1990-06-05 Choung U. Kim Carbapenem antibiotics
DK140584A (da) * 1983-03-08 1984-09-09 Bristol Myers Co Fremgangsmaade til fremstilling af carbapenemderivater
JPS60202886A (ja) * 1984-03-27 1985-10-14 Sankyo Co Ltd １―置換カルバペネム―３―カルボン酸誘導体

Also Published As

Publication number Publication date
FI863609A (fi) 1987-03-12
SE8603798D0 (sv) 1986-09-10
GB8621759D0 (en) 1986-10-15
AR242577A1 (es) 1993-04-30
ZW16186A1 (en) 1988-03-30
FR2587704A1 (fr) 1987-03-27
PT83361B (pt) 1989-05-12
CN1015261B (zh) 1992-01-01
DK433586D0 (da) 1986-09-10
YU158586A (en) 1988-02-29
KR870003110A (ko) 1987-04-15
CS656786A2 (en) 1988-03-15
AT396472B (de) 1993-09-27
ZA866638B (en) 1987-05-27
GB2180238A (en) 1987-03-25
CN86105933A (zh) 1987-05-20
CH669381A5 (sv) 1989-03-15
FI81803C (sv) 1990-12-10
IL79969A0 (en) 1986-12-31
DE3630857C2 (de) 1994-04-07
AU6234886A (en) 1987-03-12
FR2587704B1 (fr) 1989-02-24
ES2002303A6 (es) 1988-08-01
DE3630857A1 (de) 1987-03-19
ATA245286A (de) 1993-01-15
HUT42487A (en) 1987-07-28
DK433586A (da) 1987-03-12
US4665169A (en) 1987-05-12
GR862313B (en) 1987-01-12
YU45800B (sh) 1992-07-20
FI863609A0 (fi) 1986-09-08
SE469630B (sv) 1993-08-09
BE905415A (fr) 1987-03-10
DD252605A1 (de) 1987-12-23
MY102957A (en) 1993-03-31
KR910006807B1 (ko) 1991-09-02
GB2180238B (en) 1989-09-06
NL8602282A (nl) 1987-04-01
FI81803B (fi) 1990-08-31
AU596990B2 (en) 1990-05-24
LU86575A1 (fr) 1987-04-02
JPS6261980A (ja) 1987-03-18
IT1207578B (it) 1989-05-25
IT8621666A0 (it) 1986-09-10
HU198491B (en) 1989-10-30
SU1480764A3 (ru) 1989-05-15
CS259892B2 (en) 1988-11-15
NZ217519A (en) 1990-07-26
PT83361A (en) 1986-10-01

Similar Documents

Publication Publication Date Title
DE3587126D1 (de) Carbapenem-derivate und sie enthaltende zusammensetzung.
FI73969B (fi) Foerfarande foer framstaellning av terapeutiskt aktiva trans-4-aminometylcyklohexankarboxylsyraderivat.
DK345989D0 (da) Quinolinderivater
EP0358190A3 (en) Polysiloxanes with sterically hindered moiety
FI854577A (fi) Kefalosporiner.
ZA858418B (en) 5-alkyl-1-phenyl-2-piperazinoalkylpyrazoline-3-one compounds and methods for the preparation thereof,intermediates for use in the preparation of said compounds and medicaments containing said compounds
SE8603798D0 (sv) Carbapenem antibiotics
SE7702668L (sv) Nya stilbenforeningar och forfarande for deras framstellning
MX170732B (es) Composicion de derivados de succinimida y su uso
SE8305217D0 (sv) Karbapenem-antibiotika
ES442057A1 (es) Procedimiento para la obtencion de penicilinas.
ES8401766A1 (es) Procedimiento para la preparacion de nuevas acinorrifamicinas.
FR2491470B1 (sv)
GB2021586A (en) 1,2,4-Triazolidin-3-ones (and -thiones)
IE810004L (en) Rifamycin derivatives
IE42053L (en) Phosphorus thiazole derivatives
ATE87307T1 (de) Isoindolinderivate und verfahren zu ihrer herstellung.
FI892229A (fi) Antibiotikafoereningar.
PT73996A (fr) Thiovinyl-3 cephalosporines
JPS5424869A (en) Heterocyclic compounds and their preparation
ATE36536T1 (de) Phosphoroimidate.
FR2672593B1 (fr) Nouveaux composes utiles pour la resolution de la dl-n-acetyle ou la dl-n-haloacetyl-hydroxyphenylglycine.
GB1532351A (en) Substituted anilino-2-oxazolines and thiazolines

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8603798-3

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8603798-3

Format of ref document f/p: F