IT1207578B - Antibiotici carbapenem e relativo procedimento di preparazione. - Google Patents
Antibiotici carbapenem e relativo procedimento di preparazione.Info
- Publication number
- IT1207578B IT1207578B IT8621666A IT2166686A IT1207578B IT 1207578 B IT1207578 B IT 1207578B IT 8621666 A IT8621666 A IT 8621666A IT 2166686 A IT2166686 A IT 2166686A IT 1207578 B IT1207578 B IT 1207578B
- Authority
- IT
- Italy
- Prior art keywords
- preparation procedure
- carbapenem antibiotics
- related preparation
- carbapenem
- antibiotics
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/774,628 US4665169A (en) | 1985-09-11 | 1985-09-11 | Carbapenem antibiotics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8621666A0 IT8621666A0 (it) | 1986-09-10 |
| IT1207578B true IT1207578B (it) | 1989-05-25 |
Family
ID=25101800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8621666A IT1207578B (it) | 1985-09-11 | 1986-09-10 | Antibiotici carbapenem e relativo procedimento di preparazione. |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US4665169A (it) |
| JP (1) | JPS6261980A (it) |
| KR (1) | KR910006807B1 (it) |
| CN (1) | CN1015261B (it) |
| AR (1) | AR242577A1 (it) |
| AT (1) | AT396472B (it) |
| AU (1) | AU596990B2 (it) |
| BE (1) | BE905415A (it) |
| CH (1) | CH669381A5 (it) |
| CS (1) | CS259892B2 (it) |
| DD (1) | DD252605A1 (it) |
| DE (1) | DE3630857C2 (it) |
| DK (1) | DK433586A (it) |
| ES (1) | ES2002303A6 (it) |
| FI (1) | FI81803C (it) |
| FR (1) | FR2587704B1 (it) |
| GB (1) | GB2180238B (it) |
| GR (1) | GR862313B (it) |
| HU (1) | HU198491B (it) |
| IL (1) | IL79969A0 (it) |
| IT (1) | IT1207578B (it) |
| LU (1) | LU86575A1 (it) |
| MY (1) | MY102957A (it) |
| NL (1) | NL8602282A (it) |
| NZ (1) | NZ217519A (it) |
| PT (1) | PT83361B (it) |
| SE (1) | SE469630B (it) |
| SU (1) | SU1480764A3 (it) |
| YU (1) | YU45800B (it) |
| ZA (1) | ZA866638B (it) |
| ZW (1) | ZW16186A1 (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU209817B (en) * | 1989-03-28 | 1994-11-28 | Pfizer | Process for the production of antibacterial 2-carbapenem derivatives |
| US5321020A (en) * | 1989-03-28 | 1994-06-14 | Pfizer Inc. | Antibacterial 2-carbapenem derivatives |
| US5602118A (en) * | 1993-03-16 | 1997-02-11 | American Cyanamid Company | 2-thiosubstituted carbapenems |
| RU2714730C1 (ru) | 2019-04-11 | 2020-02-19 | Общество с ограниченной ответственностью "КС-ТЕХНОЛОГИИ" | Конусная инерционная дробилка с опорным подшипником скольжения |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3950357A (en) * | 1974-11-25 | 1976-04-13 | Merck & Co., Inc. | Antibiotics |
| US4235920A (en) * | 1975-11-21 | 1980-11-25 | Merck & Co., Inc. | N-Alkylated derivatives of thienamycin |
| AU4061378A (en) * | 1977-10-19 | 1980-04-17 | Merck & Co., Inc. | 1-azabicyclo (3.2.0) hept-2-enes |
| AU531084B2 (en) * | 1977-10-19 | 1983-08-11 | Merck & Co., Inc. | Azetidine derivatives |
| IE51861B1 (en) * | 1978-10-24 | 1987-04-15 | Merck & Co Inc | 6-,1-and 2-substituted-1-carbapen-2-em-3-carboxylic acids,processes for the preparation of such compounds and pharmaceutical compositions comprising such compounds |
| US4232036A (en) * | 1978-10-24 | 1980-11-04 | Merck & Co., Inc. | 6-, 1- and 2-Substituted-1-carbadethiapen-2-em-3-carboxylic acids |
| EP0082133A3 (en) * | 1979-04-19 | 1983-07-20 | Merck & Co. Inc. | A process for preparing intermediates useful for preparing 2-substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids |
| US4376774A (en) * | 1979-05-29 | 1983-03-15 | Merck & Co., Inc. | Antibiotic N-heterocyclyl thienamycin |
| US4309346A (en) * | 1980-03-27 | 1982-01-05 | Merck & Co., Inc. | Process for the preparation of 1-carbapenems and intermediates via trithioorthoacetates |
| DE3169321D1 (en) * | 1980-03-27 | 1985-04-25 | Merck & Co Inc | Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals |
| IE52147B1 (en) * | 1980-03-27 | 1987-07-08 | Merck & Co Inc | 4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation |
| EP0038869A1 (en) * | 1980-04-30 | 1981-11-04 | Merck & Co. Inc. | Process for the preparation of 1-carbapenems, and intermediates for their preparation |
| JPS56161393A (en) * | 1980-05-16 | 1981-12-11 | Sanraku Inc | Beta-lactam compound |
| CA1198440A (en) * | 1982-04-08 | 1985-12-24 | Choung U. Kim | Carbapenem antibiotics |
| US4552696A (en) * | 1982-04-09 | 1985-11-12 | Bristol-Myers Company | Carbapenem antibiotics |
| US4536335A (en) * | 1982-06-18 | 1985-08-20 | Bristol-Myers Company | Carbapenem antibiotics |
| FI832619A (fi) * | 1982-07-26 | 1984-01-27 | Sandoz Ag | Fluoralkylerade karbapenemderivat |
| NZ205626A (en) * | 1982-09-28 | 1986-12-05 | Bristol Myers Co | Carbapenem antibiotics |
| DK140584A (da) * | 1983-03-08 | 1984-09-09 | Bristol Myers Co | Fremgangsmaade til fremstilling af carbapenemderivater |
| JPS60202886A (ja) * | 1984-03-27 | 1985-10-14 | Sankyo Co Ltd | １―置換カルバペネム―３―カルボン酸誘導体 |
-
1985
- 1985-09-11 US US06/774,628 patent/US4665169A/en not_active Expired - Fee Related
-
1986
- 1986-08-08 ZW ZW161/86A patent/ZW16186A1/xx unknown
- 1986-08-29 AR AR86305095A patent/AR242577A1/es active
- 1986-09-02 ZA ZA866638A patent/ZA866638B/xx unknown
- 1986-09-04 AU AU62348/86A patent/AU596990B2/en not_active Ceased
- 1986-09-08 IL IL79969A patent/IL79969A0/xx not_active IP Right Cessation
- 1986-09-08 FI FI863609A patent/FI81803C/fi not_active IP Right Cessation
- 1986-09-08 FR FR868612540A patent/FR2587704B1/fr not_active Expired
- 1986-09-09 DD DD86294267A patent/DD252605A1/xx not_active IP Right Cessation
- 1986-09-09 NZ NZ217519A patent/NZ217519A/xx unknown
- 1986-09-09 CN CN86105933A patent/CN1015261B/zh not_active Expired
- 1986-09-10 DK DK433586A patent/DK433586A/da not_active Application Discontinuation
- 1986-09-10 GR GR862313A patent/GR862313B/el unknown
- 1986-09-10 SU SU864028122A patent/SU1480764A3/ru active
- 1986-09-10 ES ES8601760A patent/ES2002303A6/es not_active Expired
- 1986-09-10 CH CH3640/86A patent/CH669381A5/de not_active IP Right Cessation
- 1986-09-10 NL NL8602282A patent/NL8602282A/nl not_active Application Discontinuation
- 1986-09-10 JP JP61213707A patent/JPS6261980A/ja active Pending
- 1986-09-10 SE SE8603798A patent/SE469630B/sv not_active IP Right Cessation
- 1986-09-10 DE DE3630857A patent/DE3630857C2/de not_active Expired - Fee Related
- 1986-09-10 BE BE0/217150A patent/BE905415A/fr not_active IP Right Cessation
- 1986-09-10 IT IT8621666A patent/IT1207578B/it active
- 1986-09-10 LU LU86575A patent/LU86575A1/fr unknown
- 1986-09-10 GB GB8621759A patent/GB2180238B/en not_active Expired
- 1986-09-10 KR KR1019860007583A patent/KR910006807B1/ko not_active IP Right Cessation
- 1986-09-11 AT AT0245286A patent/AT396472B/de not_active IP Right Cessation
- 1986-09-11 PT PT83361A patent/PT83361B/pt not_active IP Right Cessation
- 1986-09-11 CS CS866567A patent/CS259892B2/cs unknown
- 1986-09-11 YU YU158586A patent/YU45800B/sh unknown
- 1986-09-11 HU HU863916A patent/HU198491B/hu not_active IP Right Cessation
-
1987
- 1987-10-01 MY MYPI87002710A patent/MY102957A/en unknown
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