ATA1285A - Verfahren zur herstellung von neuen cephalosporin-antibiotika - Google Patents

Verfahren zur herstellung von neuen cephalosporin-antibiotika

Info

Publication number
ATA1285A
ATA1285A AT12/85A AT1285A ATA1285A AT A1285 A ATA1285 A AT A1285A AT 12/85 A AT12/85 A AT 12/85A AT 1285 A AT1285 A AT 1285A AT A1285 A ATA1285 A AT A1285A
Authority
AT
Austria
Prior art keywords
producing new
antibiotics
new cephalosporine
cephalosporine antibiotics
producing
Prior art date
Application number
AT12/85A
Other languages
English (en)
Other versions
AT392279B (de
Inventor
Gordon Gad Weingarten
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to AT0080488A priority Critical patent/AT392073B/de
Publication of ATA1285A publication Critical patent/ATA1285A/de
Application granted granted Critical
Publication of AT392279B publication Critical patent/AT392279B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
    • C07C59/315—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups containing halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT12/85A 1984-01-03 1985-01-03 Verfahren zur herstellung von neuen cephalosporin-antibiotika AT392279B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT0080488A AT392073B (de) 1984-01-03 1988-03-25 Verfahren zur herstellung von neuen cephalosporin-antibiotika

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848400024A GB8400024D0 (en) 1984-01-03 1984-01-03 Cephalosporin antibiotics

Publications (2)

Publication Number Publication Date
ATA1285A true ATA1285A (de) 1990-08-15
AT392279B AT392279B (de) 1991-02-25

Family

ID=10554497

Family Applications (1)

Application Number Title Priority Date Filing Date
AT12/85A AT392279B (de) 1984-01-03 1985-01-03 Verfahren zur herstellung von neuen cephalosporin-antibiotika

Country Status (28)

Country Link
US (1) US4602012A (de)
JP (1) JPH0791305B2 (de)
KR (1) KR920001770B1 (de)
AT (1) AT392279B (de)
AU (1) AU578441B2 (de)
BE (1) BE901436A (de)
CA (1) CA1265512A (de)
CH (1) CH666274A5 (de)
DE (1) DE3500090A1 (de)
DK (1) DK1585A (de)
ES (2) ES8703884A1 (de)
FI (1) FI83082C (de)
FR (1) FR2557571B1 (de)
GB (2) GB8400024D0 (de)
GR (1) GR850007B (de)
HK (1) HK105890A (de)
HU (1) HU193076B (de)
IL (1) IL73989A (de)
IT (1) IT1178349B (de)
LU (1) LU85719A1 (de)
NL (1) NL8403974A (de)
NO (1) NO165400C (de)
NZ (1) NZ210725A (de)
PH (1) PH22630A (de)
PT (1) PT79787B (de)
SE (2) SE466451B (de)
SG (1) SG81390G (de)
ZA (1) ZA8545B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8320521D0 (en) * 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
DE3804841A1 (de) * 1988-02-17 1989-08-31 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
GB8810396D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
GB8810395D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
GB8810393D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
GB8810394D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
GB8810392D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
US5063224A (en) * 1990-07-09 1991-11-05 Eli Lilly And Company R-cefuroxime axetil
DK0504107T3 (da) * 1991-03-11 1995-02-13 Schweizerhall Saeurefab Fremgangsmåde til fremstilling af chlorerede carboxylsyreestere
DE59200935D1 (de) * 1991-03-11 1995-01-26 Schweizerhall Saeurefab Verfahren zur Herstellung von halogenierten Carbonsäureestern.
GB9405856D0 (en) * 1994-03-24 1994-05-11 Smithkline Beecham Plc Pharmaceutical formulation
JP2001131071A (ja) * 1999-10-29 2001-05-15 Meiji Seika Kaisha Ltd 非晶質および非晶質を含有する医薬組成物
EP1342470B1 (de) * 2002-03-04 2007-08-15 Orbus Pharma Inc. Zusammensetzungen mit schneller Freisetzung enthaltend Cefuroxime Axetil
WO2008155615A2 (en) * 2007-06-18 2008-12-24 Orchid Chemicals & Pharmaceuticals Limited An improved process for the preparation of cephalosporin antibiotic

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1453049A (en) * 1973-08-21 1976-10-20 Glaxo Lab Ltd Cephalosporing antibiotics
GB1425933A (en) * 1972-03-13 1976-02-25 Astra Laekemedel Ab Cephalosporins
GB1426717A (en) * 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
GB1571683A (en) * 1976-02-16 1980-07-16 Glaxo Operations Ltd Ester derivatives of cefuroxime
CA1094545A (en) * 1976-02-16 1981-01-27 Michael Gregson Cephalosporin antibiotics
GB1572993A (en) * 1976-02-16 1980-08-13 Glaxo Operations Ltd Ester derivatives of cefuroxime
CA1093549A (en) * 1976-02-16 1981-01-13 Michael Gregson Cephalosporin antibiotics
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
FR2476087A1 (fr) * 1980-02-18 1981-08-21 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkyl-thiomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
IT1210868B (it) * 1982-04-01 1989-09-29 Opos Biochimica Srl Derivati della cefuroxima attivi per via orale procedimenti per laloro preparazione e relative composizioni farmaceutuche.
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
GB8320521D0 (en) * 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
GB8320520D0 (en) * 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process

Also Published As

Publication number Publication date
FI850012A0 (fi) 1985-01-02
CA1265512A (en) 1990-02-06
US4602012A (en) 1986-07-22
NO850010L (no) 1985-07-04
AT392279B (de) 1991-02-25
DK1585D0 (da) 1985-01-02
SE8500011L (sv) 1985-07-04
HK105890A (en) 1990-12-21
SE8500011D0 (sv) 1985-01-02
NZ210725A (en) 1988-02-12
GB8500091D0 (en) 1985-02-13
FI850012L (fi) 1985-07-04
HUT37800A (en) 1986-02-28
GB8400024D0 (en) 1984-02-08
FI83082C (fi) 1991-05-27
FR2557571B1 (fr) 1987-04-17
FI83082B (fi) 1991-02-15
GB2152504A (en) 1985-08-07
AU3704684A (en) 1985-07-11
GR850007B (de) 1985-05-03
BE901436A (fr) 1985-07-03
PT79787B (en) 1986-12-11
CH666274A5 (de) 1988-07-15
DK1585A (da) 1985-07-04
HU193076B (en) 1987-08-28
SE466451B (sv) 1992-02-17
ES552577A0 (es) 1987-05-16
IT8449383A0 (it) 1984-12-31
DE3500090C2 (de) 1993-09-23
IL73989A (en) 1988-10-31
DE3500090A1 (de) 1985-07-11
GB2152504B (en) 1987-10-07
LU85719A1 (fr) 1985-10-22
NL8403974A (nl) 1985-08-01
IT1178349B (it) 1987-09-09
JPS60172989A (ja) 1985-09-06
SG81390G (en) 1990-11-23
ES8705891A1 (es) 1987-05-16
NO165400C (no) 1991-02-06
ES8703884A1 (es) 1987-03-01
IT8449383A1 (it) 1986-07-01
AU578441B2 (en) 1988-10-27
PT79787A (en) 1985-02-01
ZA8545B (en) 1986-09-24
FR2557571A1 (fr) 1985-07-05
NO165400B (no) 1990-10-29
KR850005446A (ko) 1985-08-26
ES539311A0 (es) 1987-03-01
PH22630A (en) 1988-10-28
KR920001770B1 (ko) 1992-03-02
IL73989A0 (en) 1985-04-30
JPH0791305B2 (ja) 1995-10-04

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