AT366387B - Verfahren zur herstellung von neuen cephalosporin-antibiotika - Google Patents

Verfahren zur herstellung von neuen cephalosporin-antibiotika

Info

Publication number
AT366387B
AT366387B AT0727279A AT727279A AT366387B AT 366387 B AT366387 B AT 366387B AT 0727279 A AT0727279 A AT 0727279A AT 727279 A AT727279 A AT 727279A AT 366387 B AT366387 B AT 366387B
Authority
AT
Austria
Prior art keywords
producing new
antibiotics
new cephalosporine
cephalosporine antibiotics
producing
Prior art date
Application number
AT0727279A
Other languages
English (en)
Other versions
ATA727279A (de
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to AT0200281A priority Critical patent/AT371124B/de
Priority to AT0200381A priority patent/AT373894B/de
Publication of ATA727279A publication Critical patent/ATA727279A/de
Application granted granted Critical
Publication of AT366387B publication Critical patent/AT366387B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
AT0727279A 1978-11-15 1979-11-14 Verfahren zur herstellung von neuen cephalosporin-antibiotika AT366387B (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT0200281A AT371124B (de) 1978-11-15 1981-05-06 Verfahren zur herstellung von neuen cephalosporin-antibiotika
AT0200381A AT373894B (de) 1978-11-15 1981-05-06 Verfahren zur herstellung von neuen cephalosporin-antibiotika sowie von deren salzen und estern

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7844595 1978-11-15
GB7844597 1978-11-15

Publications (2)

Publication Number Publication Date
ATA727279A ATA727279A (de) 1981-08-15
AT366387B true AT366387B (de) 1982-04-13

Family

ID=26269583

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0727279A AT366387B (de) 1978-11-15 1979-11-14 Verfahren zur herstellung von neuen cephalosporin-antibiotika

Country Status (17)

Country Link
US (1) US4464368A (de)
AT (1) AT366387B (de)
AU (1) AU529825B2 (de)
CA (1) CA1136616A (de)
CH (1) CH647784A5 (de)
DE (1) DE2946038A1 (de)
DK (1) DK480679A (de)
ES (3) ES485937A1 (de)
FI (1) FI793566A7 (de)
FR (1) FR2441630A1 (de)
IE (1) IE49207B1 (de)
IL (1) IL58717A (de)
LU (1) LU81884A1 (de)
NL (1) NL7908318A (de)
NO (1) NO793688L (de)
NZ (1) NZ192127A (de)
SE (1) SE7909401L (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR78245B (de) * 1980-09-12 1984-09-26 Ciba Geigy Ag
NZ198350A (en) * 1980-09-25 1985-02-28 Toyama Chemical Co Ltd Cephalosporins and intermediates;pharmaceutical compositions
DE3279470D1 (en) * 1981-04-03 1989-04-06 Fujisawa Pharmaceutical Co New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds
DE3336757A1 (de) * 1983-10-08 1985-04-25 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
CN86107947A (zh) 1985-11-22 1987-05-27 藤沢药品工业株式会社 新的头孢烯化合物及其制备方法
US5373000A (en) * 1985-12-26 1994-12-13 Eisai Co., Ltd. 7Beta-(thiadiazolyl)-2-iminoacetamido-3cephem compounds
US5084453A (en) * 1986-04-14 1992-01-28 Banyu Pharmaceutical Co., Ltd. 1-carboxy-1-vinyloxyimino aminothiazole cephalosporin derivatives
GB8611823D0 (en) * 1986-05-15 1986-06-25 Ici Plc Process
CA1293719C (en) * 1986-09-22 1991-12-31 Takao Takaya Cephem compounds and processes for preparation thereof
US5162520A (en) * 1986-09-22 1992-11-10 Fujisawa Pharmaceutical Co., Ltd. Intermediates for cephem compounds
US5624898A (en) 1989-12-05 1997-04-29 Ramsey Foundation Method for administering neurologic agents to the brain
US6407061B1 (en) 1989-12-05 2002-06-18 Chiron Corporation Method for administering insulin-like growth factor to the brain
US10000510B2 (en) 2014-08-18 2018-06-19 Merck Sharp & Dohme Corp. Salt forms of ceftolozane
WO2016109259A2 (en) 2014-12-30 2016-07-07 Merck Sharp & Dohme Corp. Synthesis of cephalosporin compounds

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024133A (en) * 1971-05-14 1977-05-17 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(thienyl-,furyl- or pyridylacetamido)]cephalosporins
US4091209A (en) * 1971-05-14 1978-05-23 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(phenyl or naphthylacetamido)]cephalosporins having a 2-haloalkylcarbamoyloxymethyl group at the 3-position
US3971778A (en) * 1972-05-12 1976-07-27 Glaxo Laboratories Limited Cephalosporins having (α-etherified oximino)acylamido groups at the 7-position
US4093803A (en) * 1971-05-14 1978-06-06 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(thienyl-, furyl- or pyridylacetamido)] cephalosporins
US4017515A (en) * 1971-05-14 1977-04-12 Glaxo Laboratories Limited α-(Etherified oximino) carboxylic acids and acid chlorides
US4079178A (en) * 1971-05-14 1978-03-14 Glaxo Laboratories Limited Cephalosporins having (α-etherified oximino) acylamido groups at the 7-position
US4024137A (en) * 1971-05-14 1977-05-17 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(phenyl- or naphthylacetamido)] cephalosporins
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
US4064346A (en) * 1971-05-14 1977-12-20 Glaxo Laboratories Limited 3-Acetoxymethyl-7β-(2-carboxy-methoxyimino-2-arylacetamido)ceph-3-em-4-carboxylic acids and salts thereof
US4144393A (en) * 1973-12-21 1979-03-13 Glaxo Laboratories Limited 3-Acetoxymethyl cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyiminoarylacetamido group
US4060686A (en) * 1973-12-21 1977-11-29 Janice Bradshaw Cephalosporins having a 7-(carboxy substituted α-etherified oximinoarylacetamido) group
US4162360A (en) * 1973-12-21 1979-07-24 Glaxo Laboratories Limited 3-Carbamoyloxymethyl-7-substituted oximino acetamido cephalosporanic acid derivatives
US4144392A (en) * 1973-12-21 1979-03-13 Glaxo Laboratories Limited Cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyimino-arylacetamido group and at position-3 the residue of a sulphur nucleophile
GB1496757A (en) * 1973-12-21 1978-01-05 Glaxo Lab Ltd Cephalosporin derivatives
US4032950A (en) * 1974-12-06 1977-06-28 Hughes Aircraft Company Liquid phase epitaxial process for growing semi-insulating gaas layers
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
US4165430A (en) * 1976-03-19 1979-08-21 Glaxo Laboratories Limited Cephalosporins having a 7-carboxy substituted α-etherified oximinoarylacetamido) group
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
FR2457296A1 (fr) * 1979-05-23 1980-12-19 Rhone Poulenc Ind Nouveaux derives de vinyl-3 cephalosporines et leur preparation
IL61458A0 (en) * 1979-12-07 1980-12-31 Erba Farmitalia N-substituted thiazolyl derivatives of oximino-substituted cephalosporins, their preparation and pharmalceutical compositions containing them
US4382932A (en) * 1981-09-08 1983-05-10 Eli Lilly And Company Isoquinolinium substituted cephalosporins

Also Published As

Publication number Publication date
AU529825B2 (en) 1983-06-23
DK480679A (da) 1980-05-16
IL58717A (en) 1983-05-15
ES485938A1 (es) 1980-07-01
IE49207B1 (en) 1985-08-21
LU81884A1 (fr) 1980-06-05
IL58717A0 (en) 1980-02-29
FR2441630B1 (de) 1983-06-03
AU5281579A (en) 1980-05-22
US4464368A (en) 1984-08-07
CA1136616A (en) 1982-11-30
CH647784A5 (de) 1985-02-15
FR2441630A1 (fr) 1980-06-13
NL7908318A (nl) 1980-05-19
SE7909401L (sv) 1980-05-16
NZ192127A (en) 1982-12-21
NO793688L (no) 1980-05-19
ES485939A1 (es) 1980-07-01
ES485937A1 (es) 1980-07-01
DE2946038A1 (de) 1980-05-29
IE792186L (en) 1980-05-15
FI793566A7 (fi) 1981-01-01
ATA727279A (de) 1981-08-15

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee