FR2441630A1 - Cephalosporines a activite antibiotique et leur procede de preparation - Google Patents
Cephalosporines a activite antibiotique et leur procede de preparationInfo
- Publication number
- FR2441630A1 FR2441630A1 FR7928103A FR7928103A FR2441630A1 FR 2441630 A1 FR2441630 A1 FR 2441630A1 FR 7928103 A FR7928103 A FR 7928103A FR 7928103 A FR7928103 A FR 7928103A FR 2441630 A1 FR2441630 A1 FR 2441630A1
- Authority
- FR
- France
- Prior art keywords
- cephalosporins
- preparation
- antibiotic activity
- represent
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 2
- 229940124587 cephalosporin Drugs 0.000 title abstract 2
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title abstract 2
- 230000003115 biocidal effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001721 carbon Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Abstract
L'INVENTION CONCERNE DES CEPHALOSPORINES. LES COMPOSES REPONDENT A LA FORMULE I CI-DESSOUS DANS LAQUELLE R ET R, IDENTIQUES OU DIFFERENTS, REPRESENTENT DES RADICAUX ALKYLE EN C-C OU UN GROUPE CYCLOALKYLIDENE EN C-C AVEC L'ATOME DE CARBONE AUQUEL ILS SONT ATTACHES ET R REPRESENTE UN GROUPE ALKYLE EN C-C. LES COMPOSES SONT DES ANTIBIOTIQUES A ACTIVITE ELEVEE CONTRE DES ORGANISMES GRAM-NEGATIFS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7844595 | 1978-11-15 | ||
GB7844597 | 1978-11-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2441630A1 true FR2441630A1 (fr) | 1980-06-13 |
FR2441630B1 FR2441630B1 (fr) | 1983-06-03 |
Family
ID=26269583
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7928103A Granted FR2441630A1 (fr) | 1978-11-15 | 1979-11-14 | Cephalosporines a activite antibiotique et leur procede de preparation |
Country Status (17)
Country | Link |
---|---|
US (1) | US4464368A (fr) |
AT (1) | AT366387B (fr) |
AU (1) | AU529825B2 (fr) |
CA (1) | CA1136616A (fr) |
CH (1) | CH647784A5 (fr) |
DE (1) | DE2946038A1 (fr) |
DK (1) | DK480679A (fr) |
ES (3) | ES485937A1 (fr) |
FI (1) | FI793566A (fr) |
FR (1) | FR2441630A1 (fr) |
IE (1) | IE49207B1 (fr) |
IL (1) | IL58717A (fr) |
LU (1) | LU81884A1 (fr) |
NL (1) | NL7908318A (fr) |
NO (1) | NO793688L (fr) |
NZ (1) | NZ192127A (fr) |
SE (1) | SE7909401L (fr) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0047977A2 (fr) * | 1980-09-12 | 1982-03-24 | Ciba-Geigy Ag | Dérivés de céphalosporines, leur préparation, compositions pharmaceutiques les contenant et leur application |
EP0062321A2 (fr) * | 1981-04-03 | 1982-10-13 | Fujisawa Pharmaceutical Co., Ltd. | Dérivés de céphalosporine, leur préparation, des compositions pharmaceutiques les contenant et leurs produits de départ |
EP0137441A2 (fr) * | 1983-10-08 | 1985-04-17 | Hoechst Aktiengesellschaft | Dérivés de céphalosporine et procédé pour leur préparation |
EP0223246A2 (fr) | 1985-11-22 | 1987-05-27 | Fujisawa Pharmaceutical Co., Ltd. | Dérivés céphem et procédés pour leur préparation |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ198350A (en) * | 1980-09-25 | 1985-02-28 | Toyama Chemical Co Ltd | Cephalosporins and intermediates;pharmaceutical compositions |
US5373000A (en) * | 1985-12-26 | 1994-12-13 | Eisai Co., Ltd. | 7Beta-(thiadiazolyl)-2-iminoacetamido-3cephem compounds |
DE3787030T2 (de) * | 1986-04-14 | 1994-04-07 | Banyu Pharma Co Ltd | 1-carboxy-1-vinyloxyiminoaminothiazol-cephalosporin-derivate und deren herstellung. |
GB8611823D0 (en) * | 1986-05-15 | 1986-06-25 | Ici Plc | Process |
CA1293719C (fr) * | 1986-09-22 | 1991-12-31 | Takao Takaya | Composes de cephem et procede de preparation |
US5162520A (en) * | 1986-09-22 | 1992-11-10 | Fujisawa Pharmaceutical Co., Ltd. | Intermediates for cephem compounds |
US5624898A (en) | 1989-12-05 | 1997-04-29 | Ramsey Foundation | Method for administering neurologic agents to the brain |
US6407061B1 (en) | 1989-12-05 | 2002-06-18 | Chiron Corporation | Method for administering insulin-like growth factor to the brain |
WO2016028670A1 (fr) * | 2014-08-18 | 2016-02-25 | Merck Sharp & Dohme Corp. | Formes salines de ceftolozane |
WO2016109259A2 (fr) | 2014-12-30 | 2016-07-07 | Merck Sharp & Dohme Corp. | Synthèse de composés de céphalosporine |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4064346A (en) * | 1971-05-14 | 1977-12-20 | Glaxo Laboratories Limited | 3-Acetoxymethyl-7β-(2-carboxy-methoxyimino-2-arylacetamido)ceph-3-em-4-carboxylic acids and salts thereof |
US4091209A (en) * | 1971-05-14 | 1978-05-23 | Glaxo Laboratories Limited | 7β-[2-Etherified oximino-2-(phenyl or naphthylacetamido)]cephalosporins having a 2-haloalkylcarbamoyloxymethyl group at the 3-position |
GB1399086A (en) * | 1971-05-14 | 1975-06-25 | Glaxo Lab Ltd | Cephalosporin compounds |
US4024133A (en) * | 1971-05-14 | 1977-05-17 | Glaxo Laboratories Limited | 7β-[2-Etherified oximino-2-(thienyl-,furyl- or pyridylacetamido)]cephalosporins |
US4024137A (en) * | 1971-05-14 | 1977-05-17 | Glaxo Laboratories Limited | 7β-[2-Etherified oximino-2-(phenyl- or naphthylacetamido)] cephalosporins |
US4017515A (en) * | 1971-05-14 | 1977-04-12 | Glaxo Laboratories Limited | α-(Etherified oximino) carboxylic acids and acid chlorides |
US3971778A (en) * | 1972-05-12 | 1976-07-27 | Glaxo Laboratories Limited | Cephalosporins having (α-etherified oximino)acylamido groups at the 7-position |
US4093803A (en) * | 1971-05-14 | 1978-06-06 | Glaxo Laboratories Limited | 7β-[2-Etherified oximino-2-(thienyl-, furyl- or pyridylacetamido)] cephalosporins |
US4079178A (en) * | 1971-05-14 | 1978-03-14 | Glaxo Laboratories Limited | Cephalosporins having (α-etherified oximino) acylamido groups at the 7-position |
US4162360A (en) * | 1973-12-21 | 1979-07-24 | Glaxo Laboratories Limited | 3-Carbamoyloxymethyl-7-substituted oximino acetamido cephalosporanic acid derivatives |
US4144393A (en) * | 1973-12-21 | 1979-03-13 | Glaxo Laboratories Limited | 3-Acetoxymethyl cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyiminoarylacetamido group |
GB1496757A (en) * | 1973-12-21 | 1978-01-05 | Glaxo Lab Ltd | Cephalosporin derivatives |
US4060686A (en) * | 1973-12-21 | 1977-11-29 | Janice Bradshaw | Cephalosporins having a 7-(carboxy substituted α-etherified oximinoarylacetamido) group |
US4144392A (en) * | 1973-12-21 | 1979-03-13 | Glaxo Laboratories Limited | Cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyimino-arylacetamido group and at position-3 the residue of a sulphur nucleophile |
US4032950A (en) * | 1974-12-06 | 1977-06-28 | Hughes Aircraft Company | Liquid phase epitaxial process for growing semi-insulating gaas layers |
DK154939C (da) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
DE2760123C2 (de) * | 1976-01-23 | 1986-04-30 | Roussel-Uclaf, Paris | 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
US4165430A (en) * | 1976-03-19 | 1979-08-21 | Glaxo Laboratories Limited | Cephalosporins having a 7-carboxy substituted α-etherified oximinoarylacetamido) group |
US4166115A (en) * | 1976-04-12 | 1979-08-28 | Fujisawa Pharmaceutical Co., Ltd. | Syn 7-oxoimino substituted derivatives of cephalosporanic acid |
FR2457296A1 (fr) * | 1979-05-23 | 1980-12-19 | Rhone Poulenc Ind | Nouveaux derives de vinyl-3 cephalosporines et leur preparation |
IL61458A0 (en) * | 1979-12-07 | 1980-12-31 | Erba Farmitalia | N-substituted thiazolyl derivatives of oximino-substituted cephalosporins, their preparation and pharmalceutical compositions containing them |
US4382932A (en) * | 1981-09-08 | 1983-05-10 | Eli Lilly And Company | Isoquinolinium substituted cephalosporins |
-
1979
- 1979-11-14 DE DE19792946038 patent/DE2946038A1/de not_active Withdrawn
- 1979-11-14 IE IE2186/79A patent/IE49207B1/en unknown
- 1979-11-14 FR FR7928103A patent/FR2441630A1/fr active Granted
- 1979-11-14 ES ES485937A patent/ES485937A1/es not_active Expired
- 1979-11-14 AT AT0727279A patent/AT366387B/de not_active IP Right Cessation
- 1979-11-14 NO NO793688A patent/NO793688L/no unknown
- 1979-11-14 DK DK480679A patent/DK480679A/da not_active Application Discontinuation
- 1979-11-14 ES ES485939A patent/ES485939A1/es not_active Expired
- 1979-11-14 NZ NZ192127A patent/NZ192127A/xx unknown
- 1979-11-14 AU AU52815/79A patent/AU529825B2/en not_active Ceased
- 1979-11-14 CH CH10175/79A patent/CH647784A5/de not_active IP Right Cessation
- 1979-11-14 FI FI793566A patent/FI793566A/fi not_active Application Discontinuation
- 1979-11-14 ES ES485938A patent/ES485938A1/es not_active Expired
- 1979-11-14 SE SE7909401A patent/SE7909401L/xx not_active Application Discontinuation
- 1979-11-14 LU LU81884A patent/LU81884A1/fr unknown
- 1979-11-14 CA CA000339879A patent/CA1136616A/fr not_active Expired
- 1979-11-14 IL IL58717A patent/IL58717A/xx unknown
- 1979-11-14 NL NL7908318A patent/NL7908318A/xx not_active Application Discontinuation
-
1981
- 1981-07-23 US US06/285,966 patent/US4464368A/en not_active Expired - Fee Related
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0047977A2 (fr) * | 1980-09-12 | 1982-03-24 | Ciba-Geigy Ag | Dérivés de céphalosporines, leur préparation, compositions pharmaceutiques les contenant et leur application |
EP0047977A3 (fr) * | 1980-09-12 | 1982-10-13 | Ciba-Geigy Ag | Dérivés de céphalosporines, leur préparation, compositions pharmaceutiques les contenant et leur application |
EP0062321A2 (fr) * | 1981-04-03 | 1982-10-13 | Fujisawa Pharmaceutical Co., Ltd. | Dérivés de céphalosporine, leur préparation, des compositions pharmaceutiques les contenant et leurs produits de départ |
EP0062321A3 (en) * | 1981-04-03 | 1983-11-09 | Fujisawa Pharmaceutical Co., Ltd. | New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds |
EP0137441A2 (fr) * | 1983-10-08 | 1985-04-17 | Hoechst Aktiengesellschaft | Dérivés de céphalosporine et procédé pour leur préparation |
EP0137441A3 (fr) * | 1983-10-08 | 1986-01-15 | Hoechst Aktiengesellschaft | Dérivés de céphalosporine et procédé pour leur préparation |
EP0223246A2 (fr) | 1985-11-22 | 1987-05-27 | Fujisawa Pharmaceutical Co., Ltd. | Dérivés céphem et procédés pour leur préparation |
EP0223246A3 (en) * | 1985-11-22 | 1988-11-23 | Fujisawa Pharmaceutical Co., Ltd. | New cephem compounds and processes for preparation thereof |
Also Published As
Publication number | Publication date |
---|---|
IE792186L (en) | 1980-05-15 |
NO793688L (no) | 1980-05-19 |
IE49207B1 (en) | 1985-08-21 |
IL58717A0 (en) | 1980-02-29 |
AU529825B2 (en) | 1983-06-23 |
ATA727279A (de) | 1981-08-15 |
ES485937A1 (es) | 1980-07-01 |
DE2946038A1 (de) | 1980-05-29 |
CA1136616A (fr) | 1982-11-30 |
FI793566A (fi) | 1980-05-16 |
DK480679A (da) | 1980-05-16 |
ES485939A1 (es) | 1980-07-01 |
NL7908318A (nl) | 1980-05-19 |
FR2441630B1 (fr) | 1983-06-03 |
AT366387B (de) | 1982-04-13 |
IL58717A (en) | 1983-05-15 |
CH647784A5 (de) | 1985-02-15 |
US4464368A (en) | 1984-08-07 |
LU81884A1 (fr) | 1980-06-05 |
NZ192127A (en) | 1982-12-21 |
ES485938A1 (es) | 1980-07-01 |
SE7909401L (sv) | 1980-05-16 |
AU5281579A (en) | 1980-05-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |