AR077412A2 - Formulacion farmaceutica composicon farmaceutica acuosa y formulacion farmaceutica acuosa liquida que comprende un anticuerpo - Google Patents

Formulacion farmaceutica composicon farmaceutica acuosa y formulacion farmaceutica acuosa liquida que comprende un anticuerpo

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Publication number
AR077412A2
AR077412A2 ARP100102557A ARP100102557A AR077412A2 AR 077412 A2 AR077412 A2 AR 077412A2 AR P100102557 A ARP100102557 A AR P100102557A AR P100102557 A ARP100102557 A AR P100102557A AR 077412 A2 AR077412 A2 AR 077412A2
Authority
AR
Argentina
Prior art keywords
formulation
pharmaceutical
acuosa
pharmaceutical formulation
antibody
Prior art date
Application number
ARP100102557A
Other languages
English (en)
Inventor
Hans-Juergen Krause
Michael Dickes
Lisa Baust
Original Assignee
Abbott Biotech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31714885&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR077412(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Biotech Ltd filed Critical Abbott Biotech Ltd
Publication of AR077412A2 publication Critical patent/AR077412A2/es

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    • C—CHEMISTRY; METALLURGY
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Abstract

Reivindicacion 1: Una formulacion farmacéutica, caracterizada porque se selecciona del grupo formado por: (a) una formulacion farmacéutica acuosa líquida que comprende una cantidad eficaz para uso farmacéutico de un anticuerpo en una solucion amortiguadora, donde dicha formulacion tiene un valor de pH entre aproximadamente 4 y 8 y una vida en estante de al menos 18 meses, (b) una formulacion farmacéutica acuosa que comprende una cantidad eficaz para uso farmacéutico de un anticuerpo en una solucion amortiguadora, donde dicha formulacion tiene un valor de pH entre aproximadamente 4 y 8 y una vida en estante de al menos 18 meses en estado líquido, (c) una formulacion farmacéutica acuosa líquida que comprende una cantidad eficaz para uso farmacéutico de un anticuerpo en una solucion amortiguadora, donde dicha formulacion tiene un valor de pH entre aproximadamente 4 y 8 que mantiene la estabilidad después de al menos 3 ciclos de congelamiento/descongelamiento de la formulacion; y (d) una formulacion farmacéutica acuosa líquida que comprende una cantidad eficaz para uso farmacéutico de un anticuerpo en una solucion amortiguadora, donde dicha formulacion tiene un valor de pH entre aproximadamente 4 y 8 y una mayor estabilidad de al menos 12 meses a una temperatura de 2-8sC.
ARP100102557A 2002-08-16 2010-07-14 Formulacion farmaceutica composicon farmaceutica acuosa y formulacion farmaceutica acuosa liquida que comprende un anticuerpo AR077412A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/222,140 US20040033228A1 (en) 2002-08-16 2002-08-16 Formulation of human antibodies for treating TNF-alpha associated disorders

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