ES2151464T3 - Preparacion para aplicacion externa que comprende tranilast y procedimiento para producirla. - Google Patents

Preparacion para aplicacion externa que comprende tranilast y procedimiento para producirla.

Info

Publication number
ES2151464T3
ES2151464T3 ES97902588T ES97902588T ES2151464T3 ES 2151464 T3 ES2151464 T3 ES 2151464T3 ES 97902588 T ES97902588 T ES 97902588T ES 97902588 T ES97902588 T ES 97902588T ES 2151464 T3 ES2151464 T3 ES 2151464T3
Authority
ES
Spain
Prior art keywords
tranilast
preparation
external application
procedure
produce
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97902588T
Other languages
English (en)
Other versions
ES2151464T1 (es
Inventor
Masao Mori
Noriyasu Saito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Lead Chemical Co Ltd
Original Assignee
Kissei Pharmaceutical Co Ltd
Lead Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical Co Ltd, Lead Chemical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Publication of ES2151464T1 publication Critical patent/ES2151464T1/es
Application granted granted Critical
Publication of ES2151464T3 publication Critical patent/ES2151464T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Una preparación para aplicación externa que contiene una base acuosa que comprende tranilast, su sal, o una de sus mezclas en calidad de ingrediente activo, conteniendo la preparación para aplicación externa tranilast, caracterizada porque dicha base acuosa comprende un medio de disolución para disolver el tranilast, un dispersante, un adyuvante de absorción, un adhesivo y/o un agente mantenedor de la forma, y agua, y/o el ingrediente activo está disuelto en dicho medio de disolución y dispersado en la base acuosa por medio de dicho dispersante.
ES97902588T 1996-02-07 1997-02-06 Preparacion para aplicacion externa que comprende tranilast y procedimiento para producirla. Expired - Lifetime ES2151464T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4549396 1996-02-07

Publications (2)

Publication Number Publication Date
ES2151464T1 ES2151464T1 (es) 2001-01-01
ES2151464T3 true ES2151464T3 (es) 2002-12-16

Family

ID=12720933

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97902588T Expired - Lifetime ES2151464T3 (es) 1996-02-07 1997-02-06 Preparacion para aplicacion externa que comprende tranilast y procedimiento para producirla.

Country Status (12)

Country Link
US (1) US6239177B1 (es)
EP (1) EP0974350B1 (es)
JP (1) JP4154621B2 (es)
KR (1) KR100449939B1 (es)
CN (1) CN1081030C (es)
AT (1) ATE222759T1 (es)
DE (2) DE974350T1 (es)
DK (1) DK0974350T3 (es)
ES (1) ES2151464T3 (es)
HK (1) HK1018218A1 (es)
PT (1) PT974350E (es)
WO (1) WO1997028793A1 (es)

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CZ258598A3 (cs) * 1996-02-15 1998-11-11 Kissei Pharmaceutical Co., Ltd. Inhibitor neovaskularizace
JP4865958B2 (ja) * 2001-05-23 2012-02-01 株式会社トクホン 鎮痛抗炎症局所作用型の貼付剤
DE60239165D1 (de) * 2002-11-05 2011-03-24 Lead Chem Co Ltd Perkutane absorptionszubereitungen mit 3-methyl-1-phenyl-2-pyrazolin-5-on
JP2004307364A (ja) * 2003-04-03 2004-11-04 Yuutoku Yakuhin Kogyo Kk 経皮吸収貼付剤
EP1685837A4 (en) * 2003-11-12 2009-03-25 Lead Chem Co Ltd BRAIN PROTECTIVE AGENT OF THE TYPE ADMINISTERED BY PERCUTANEOUS ABSORPTION
US9066912B2 (en) * 2003-11-17 2015-06-30 Ethicon, Inc. Drug-enhanced adhesion prevention
US20050106230A1 (en) * 2003-11-17 2005-05-19 Young Janel E. Drug-enhanced adhesion prevention
US20050239892A1 (en) * 2003-11-21 2005-10-27 Trustees Of Tufts College Therapeutic avenathramide compounds
US7105263B2 (en) * 2003-12-30 2006-09-12 Samsung Electronics Company Dry toner comprising encapsulated pigment, methods and uses
JP4590224B2 (ja) * 2004-07-20 2010-12-01 株式会社日本点眼薬研究所 トラニラストまたは薬理学的に許容される塩を含有する懸濁性医薬組成物
US7592371B2 (en) 2004-08-18 2009-09-22 Medrx Co., Ltd. External preparation
US7473738B2 (en) * 2004-09-30 2009-01-06 Johnson & Johnson Vision Care, Inc. Lactam polymer derivatives
BRPI0518432A2 (pt) * 2004-11-17 2008-11-25 Angiogen Pharmaceuticals Pty L mÉtodo de modular o funcionamento de cÉlula b
US20080009519A1 (en) * 2004-11-17 2008-01-10 Lawrence Steinman Method of modulating t cell functioning
JP2007051089A (ja) * 2005-08-18 2007-03-01 Medorekkusu:Kk 外用剤
WO2007046544A1 (ja) * 2005-10-21 2007-04-26 Medrx Co., Ltd. カルボキシル基を有する肥満細胞脱顆粒抑制剤と有機アミンとの塩を含有する外用剤
JP4959991B2 (ja) * 2006-03-03 2012-06-27 株式会社日本点眼薬研究所 トラニラストまたはその薬理学的に許容される塩を含有する懸濁性医薬組成物
MX352516B (es) 2006-07-05 2017-04-06 Fibrotech Therapeutics Pty Ltd Compuestos terapeuticos.
US8668703B2 (en) * 2006-12-01 2014-03-11 Wake Forest University Health Sciences Medical devices incorporating collagen inhibitors
EP2030617A1 (en) * 2007-08-17 2009-03-04 Sygnis Bioscience GmbH & Co. KG Use of tranilast and derivatives thereof for the therapy of neurological conditions
CN101152164B (zh) * 2007-09-14 2011-04-06 李世荣 含有抗肥大细胞类药物的抗瘢痕外用贴膜及其制备方法
CN101152163B (zh) * 2007-09-14 2010-05-26 李世荣 含有激素类药物的抗瘢痕外用贴膜及其制备方法
JP5904944B2 (ja) 2009-10-22 2016-04-20 フィブロテック セラピューティクス プロプライエタリー リミテッド 縮合環類似体の抗線維症剤
WO2012176668A1 (ja) * 2011-06-20 2012-12-27 久光製薬株式会社 リドカイン含有パップ剤
JP6096021B2 (ja) * 2013-03-22 2017-03-15 ファイテン株式会社 顎関節症用外用剤
JP6558117B2 (ja) * 2014-08-19 2019-08-14 大正製薬株式会社 皮膚用剤
MA41266A (fr) * 2014-12-22 2017-10-31 Hisamitsu Pharmaceutical Co Cataplasme
US10940121B2 (en) 2015-02-24 2021-03-09 Hisamitsu Pharmaceutical Co., Inc. Gel patch
CN104784101A (zh) * 2015-03-05 2015-07-22 中国药科大学制药有限公司 一种曲尼司特凝胶和软膏剂的处方及制备方法
KR101691472B1 (ko) 2015-07-06 2017-01-09 이광재 배낭에 탈착이 용이한 스틱 걸이
US20190175554A1 (en) * 2016-08-23 2019-06-13 Neurim Pharmaceuticals (1991) Ltd. Method for treating pruritus and/or itch
US11014873B2 (en) 2017-02-03 2021-05-25 Certa Therapeutics Pty Ltd. Anti-fibrotic compounds
CN108324724A (zh) * 2018-04-10 2018-07-27 苏州芝宇生物科技有限公司 一种克立硼罗可溶性膜制剂的制法及其应用
US11903915B2 (en) 2019-02-14 2024-02-20 Hisamitsu Pharmaceutical Co., Inc. Poultice

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US5124317A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
JPS62169723A (ja) * 1986-01-22 1987-07-25 Teisan Seiyaku Kk 徐放化製剤
JPS63238024A (ja) * 1987-03-26 1988-10-04 Towa Yakuhin Kk 水難溶性薬物を含有する外用ゲル組成物
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US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
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JPH01294620A (ja) * 1988-05-19 1989-11-28 Kissei Pharmaceut Co Ltd 水溶液製剤およびその製造方法
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JP3243564B2 (ja) * 1990-08-20 2002-01-07 リードケミカル株式会社 外用貼付剤
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Also Published As

Publication number Publication date
KR100449939B1 (ko) 2004-11-20
US6239177B1 (en) 2001-05-29
PT974350E (pt) 2002-12-31
CN1210462A (zh) 1999-03-10
KR19990082254A (ko) 1999-11-25
ES2151464T1 (es) 2001-01-01
DK0974350T3 (da) 2002-11-25
EP0974350A4 (en) 2000-01-26
JP4154621B2 (ja) 2008-09-24
HK1018218A1 (en) 1999-12-17
DE69715049D1 (de) 2002-10-02
EP0974350B1 (en) 2002-08-28
EP0974350A1 (en) 2000-01-26
DE974350T1 (de) 2001-01-25
CN1081030C (zh) 2002-03-20
DE69715049T2 (de) 2003-04-03
ATE222759T1 (de) 2002-09-15
WO1997028793A1 (fr) 1997-08-14

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