NO20032388D0 - Salter av et isotiazol-4-karboksamid og anvendelse derav som anti-hyperproliferasjonsmidler - Google Patents

Salter av et isotiazol-4-karboksamid og anvendelse derav som anti-hyperproliferasjonsmidler

Info

Publication number
NO20032388D0
NO20032388D0 NO20032388A NO20032388A NO20032388D0 NO 20032388 D0 NO20032388 D0 NO 20032388D0 NO 20032388 A NO20032388 A NO 20032388A NO 20032388 A NO20032388 A NO 20032388A NO 20032388 D0 NO20032388 D0 NO 20032388D0
Authority
NO
Norway
Prior art keywords
isothiazole
carboxamide
salts
hyperproliferative agents
hyperproliferative
Prior art date
Application number
NO20032388A
Other languages
English (en)
Other versions
NO325187B1 (no
NO20032388L (no
Inventor
Thomas G Gant
Glenn Robert Williams
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20032388D0 publication Critical patent/NO20032388D0/no
Publication of NO20032388L publication Critical patent/NO20032388L/no
Publication of NO325187B1 publication Critical patent/NO325187B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20032388A 2000-11-28 2003-05-27 Hydrobromidsalt og hemisuksinatsalt av et isotiazol-4-karboksamid samt anvendelse og fremstilling derav, og farmasoytisk preparat NO325187B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25351300P 2000-11-28 2000-11-28
PCT/IB2001/002193 WO2002044158A1 (en) 2000-11-28 2001-11-19 Salts of a isothiazole-4-carboxamide and their use as anti-hyperproliferation agents

Publications (3)

Publication Number Publication Date
NO20032388D0 true NO20032388D0 (no) 2003-05-27
NO20032388L NO20032388L (no) 2003-07-18
NO325187B1 NO325187B1 (no) 2008-02-11

Family

ID=22960587

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20032388A NO325187B1 (no) 2000-11-28 2003-05-27 Hydrobromidsalt og hemisuksinatsalt av et isotiazol-4-karboksamid samt anvendelse og fremstilling derav, og farmasoytisk preparat

Country Status (50)

Country Link
US (1) US6831091B2 (no)
EP (1) EP1337521B1 (no)
JP (2) JP2004514714A (no)
KR (2) KR20050116401A (no)
CN (1) CN1231474C (no)
AP (1) AP2001002358A0 (no)
AR (1) AR031512A1 (no)
AT (1) ATE340786T1 (no)
AU (2) AU2002214204B2 (no)
BG (1) BG107752A (no)
BR (1) BR0115621A (no)
CA (1) CA2430065C (no)
CR (1) CR6963A (no)
CY (1) CY1106240T1 (no)
CZ (1) CZ20031315A3 (no)
DE (1) DE60123461T2 (no)
DK (1) DK1337521T3 (no)
DO (1) DOP2001000288A (no)
EA (1) EA005859B1 (no)
EC (1) ECSP034628A (no)
EE (1) EE200300247A (no)
ES (1) ES2271086T3 (no)
GE (1) GEP20053652B (no)
GT (1) GT200100237A (no)
HK (1) HK1059085A1 (no)
HN (1) HN2001000268A (no)
HR (1) HRP20030408A2 (no)
HU (1) HUP0302553A3 (no)
IL (1) IL155371A0 (no)
IS (1) IS6788A (no)
MA (1) MA26960A1 (no)
MX (1) MXPA03004714A (no)
MY (1) MY136686A (no)
NO (1) NO325187B1 (no)
NZ (1) NZ525788A (no)
OA (1) OA12532A (no)
PA (1) PA8533801A1 (no)
PE (1) PE20020591A1 (no)
PL (1) PL362079A1 (no)
PT (1) PT1337521E (no)
SI (1) SI1337521T1 (no)
SK (1) SK5862003A3 (no)
SV (1) SV2002000748A (no)
TN (1) TNSN01167A1 (no)
TW (1) TWI287542B (no)
UA (1) UA74221C2 (no)
UY (1) UY27039A1 (no)
WO (1) WO2002044158A1 (no)
YU (1) YU36403A (no)
ZA (1) ZA200303341B (no)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA60365C2 (uk) * 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
CA2359244C (en) 1999-01-13 2013-10-08 Bayer Corporation .omega.-carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
WO2003068229A1 (en) 2002-02-11 2003-08-21 Bayer Pharmaceuticals Corporation Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors
DK1478358T3 (da) 2002-02-11 2013-10-07 Bayer Healthcare Llc Sorafenibtosylat til behandling af sygdomme kendetegnet ved unormal angiogenese
MXPA05000950A (es) * 2002-07-25 2005-05-16 Pfizer Prod Inc Derivados de isotiazol utiles como agentes anticancerosos.
CN1681495B (zh) * 2002-08-19 2010-05-12 辉瑞产品公司 用于治疗过度增生性疾病的组合物
PT1626714E (pt) 2003-05-20 2007-08-24 Bayer Pharmaceuticals Corp Diarilureias para doenças mediadas por pdgfr
ES2297490T3 (es) 2003-07-23 2008-05-01 Bayer Pharmaceuticals Corporation Omega-carboxiarildifenilurea fluoro sustituida para el tratamiento y prevencion de enfermadades y afecciones.
EP1682135B1 (en) * 2003-10-27 2011-07-27 Merck Sharp & Dohme Corp. salt of a tetrahydropyranyl cyclopentyl tetrahydropyridopyridine derivative as CCR2-antagonist
EP1694686A1 (en) 2003-12-19 2006-08-30 Takeda San Diego, Inc. Kinase inhibitors
WO2005102327A1 (en) * 2004-04-20 2005-11-03 Pfizer Products Inc. Dosage forms and methods of treatment using vegfr inhibitors
ATE517885T1 (de) 2004-04-30 2011-08-15 Bayer Healthcare Llc Substituierte pyrazolyl-harnstoff-derivate zur behandlung von krebs
TW200538104A (en) * 2004-05-17 2005-12-01 Pfizer Prod Inc Phenyl derivatives for the treatment of abnormal cell growth
US7550598B2 (en) 2004-08-18 2009-06-23 Takeda Pharmaceutical Company Limited Kinase inhibitors
US7713973B2 (en) 2004-10-15 2010-05-11 Takeda Pharmaceutical Company Limited Kinase inhibitors
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
WO2007144005A1 (en) 2006-06-16 2007-12-21 H. Lundbeck A/S 1- [2- (2, 4-dimethylphenylsulfanyl) -phenyl] piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment
US7932390B2 (en) 2006-06-29 2011-04-26 Hoffman-La Roche Inc. Substituted thieno[3,2-C]pyridine carboxylic acid derivatives
SG175609A1 (en) 2006-10-09 2011-11-28 Takeda Pharmaceutical Kinase inhibitors
MX2010001636A (es) 2007-08-14 2010-03-15 Hoffmann La Roche Derivados de pirazolo[3,4-d]-pirimidina como agentes antiproliferativos.
WO2011073521A1 (en) 2009-12-15 2011-06-23 Petri Salven Methods for enriching adult-derived endothelial progenitor cells and uses thereof
EP2596026B1 (en) 2010-07-23 2020-04-08 Trustees of Boston University Anti-despr inhibitors as therapeutics for inhibition of pathological angiogenesis and tumor cell invasiveness and for molecular imaging and targeted delivery
CN105142686B (zh) 2013-03-14 2020-04-10 帕恩欧普佳有限公司 给药于眼后段的眼用制剂
ES2863601T3 (es) * 2014-09-17 2021-10-11 Panoptica Inc Formulaciones oculares para administración de fármacos y protección del segmento anterior del ojo
TW202426440A (zh) * 2022-12-28 2024-07-01 大陸商蘇州必揚醫藥科技有限公司 一種蛋白酪胺酸激酶抑制劑及其醫藥用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA60365C2 (uk) * 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця

Also Published As

Publication number Publication date
IL155371A0 (en) 2003-11-23
BG107752A (bg) 2004-01-30
CY1106240T1 (el) 2011-06-08
DOP2001000288A (es) 2002-12-15
US20020151573A1 (en) 2002-10-17
NO325187B1 (no) 2008-02-11
GEP20053652B (en) 2005-11-10
IS6788A (is) 2003-04-14
MY136686A (en) 2008-11-28
EP1337521A1 (en) 2003-08-27
EA200300424A1 (ru) 2003-10-30
SV2002000748A (es) 2002-12-02
CA2430065C (en) 2008-05-20
CA2430065A1 (en) 2002-06-06
CR6963A (es) 2003-11-25
HK1059085A1 (en) 2004-06-18
DE60123461D1 (de) 2006-11-09
EE200300247A (et) 2003-10-15
KR20050116401A (ko) 2005-12-12
OA12532A (en) 2006-06-02
BR0115621A (pt) 2003-09-02
ECSP034628A (es) 2003-07-25
ATE340786T1 (de) 2006-10-15
HUP0302553A2 (hu) 2003-11-28
US6831091B2 (en) 2004-12-14
AR031512A1 (es) 2003-09-24
MA26960A1 (fr) 2004-12-20
PA8533801A1 (es) 2002-10-31
HN2001000268A (es) 2002-01-30
AP2001002358A0 (en) 2001-12-31
UY27039A1 (es) 2002-07-31
UA74221C2 (uk) 2005-11-15
TNSN01167A1 (fr) 2005-11-10
JP2008056692A (ja) 2008-03-13
ZA200303341B (en) 2004-04-30
TWI287542B (en) 2007-10-01
JP2004514714A (ja) 2004-05-20
HUP0302553A3 (en) 2009-03-30
JP4971946B2 (ja) 2012-07-11
AU2002214204B2 (en) 2007-05-24
EP1337521B1 (en) 2006-09-27
GT200100237A (es) 2002-07-03
ES2271086T3 (es) 2007-04-16
PT1337521E (pt) 2006-12-29
WO2002044158A1 (en) 2002-06-06
NO20032388L (no) 2003-07-18
PL362079A1 (en) 2004-10-18
CN1231474C (zh) 2005-12-14
EA005859B1 (ru) 2005-06-30
CZ20031315A3 (cs) 2004-04-14
PE20020591A1 (es) 2002-07-06
CN1476439A (zh) 2004-02-18
MXPA03004714A (es) 2003-08-19
SK5862003A3 (en) 2004-05-04
DE60123461T2 (de) 2007-02-15
AU1420402A (en) 2002-06-11
NZ525788A (en) 2004-11-26
SI1337521T1 (sl) 2006-12-31
DK1337521T3 (da) 2007-01-29
HRP20030408A2 (en) 2003-08-31
YU36403A (sh) 2006-08-17
KR20030059275A (ko) 2003-07-07

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