IS6788A - Sölt af ísóþíasól-4-karboxamíði og notkun þeirra sem efnisþættir gegn offjölgun (proliferation) - Google Patents

Sölt af ísóþíasól-4-karboxamíði og notkun þeirra sem efnisþættir gegn offjölgun (proliferation)

Info

Publication number
IS6788A
IS6788A IS6788A IS6788A IS6788A IS 6788 A IS6788 A IS 6788A IS 6788 A IS6788 A IS 6788A IS 6788 A IS6788 A IS 6788A IS 6788 A IS6788 A IS 6788A
Authority
IS
Iceland
Prior art keywords
isothiazole
carboxamide
proliferation
salts
components
Prior art date
Application number
IS6788A
Other languages
English (en)
Inventor
G. Gant Thomas
Robert Williams Glenn
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of IS6788A publication Critical patent/IS6788A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IS6788A 2000-11-28 2003-04-14 Sölt af ísóþíasól-4-karboxamíði og notkun þeirra sem efnisþættir gegn offjölgun (proliferation) IS6788A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25351300P 2000-11-28 2000-11-28
PCT/IB2001/002193 WO2002044158A1 (en) 2000-11-28 2001-11-19 Salts of a isothiazole-4-carboxamide and their use as anti-hyperproliferation agents

Publications (1)

Publication Number Publication Date
IS6788A true IS6788A (is) 2003-04-14

Family

ID=22960587

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6788A IS6788A (is) 2000-11-28 2003-04-14 Sölt af ísóþíasól-4-karboxamíði og notkun þeirra sem efnisþættir gegn offjölgun (proliferation)

Country Status (49)

Country Link
US (1) US6831091B2 (is)
EP (1) EP1337521B1 (is)
JP (2) JP2004514714A (is)
KR (2) KR20050116401A (is)
CN (1) CN1231474C (is)
AP (1) AP2001002358A0 (is)
AR (1) AR031512A1 (is)
AT (1) ATE340786T1 (is)
AU (2) AU2002214204B2 (is)
BG (1) BG107752A (is)
BR (1) BR0115621A (is)
CA (1) CA2430065C (is)
CR (1) CR6963A (is)
CY (1) CY1106240T1 (is)
CZ (1) CZ20031315A3 (is)
DE (1) DE60123461T2 (is)
DK (1) DK1337521T3 (is)
DO (1) DOP2001000288A (is)
EA (1) EA005859B1 (is)
EC (1) ECSP034628A (is)
EE (1) EE200300247A (is)
ES (1) ES2271086T3 (is)
GE (1) GEP20053652B (is)
GT (1) GT200100237A (is)
HN (1) HN2001000268A (is)
HR (1) HRP20030408A2 (is)
HU (1) HUP0302553A3 (is)
IL (1) IL155371A0 (is)
IS (1) IS6788A (is)
MA (1) MA26960A1 (is)
MX (1) MXPA03004714A (is)
MY (1) MY136686A (is)
NO (1) NO325187B1 (is)
NZ (1) NZ525788A (is)
OA (1) OA12532A (is)
PA (1) PA8533801A1 (is)
PE (1) PE20020591A1 (is)
PL (1) PL362079A1 (is)
PT (1) PT1337521E (is)
SI (1) SI1337521T1 (is)
SK (1) SK5862003A3 (is)
SV (1) SV2002000748A (is)
TN (1) TNSN01167A1 (is)
TW (1) TWI287542B (is)
UA (1) UA74221C2 (is)
UY (1) UY27039A1 (is)
WO (1) WO2002044158A1 (is)
YU (1) YU36403A (is)
ZA (1) ZA200303341B (is)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA60365C2 (uk) * 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
IL144144A0 (en) 1999-01-13 2002-05-23 Bayer Ag Omega-carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
ME00275B (me) 1999-01-13 2011-02-10 Bayer Corp ω-KARBOKSIARIL SUPSTITUISANI DIFENIL KARBAMIDI KAO INHIBITORI RAF KINAZE
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
EP1478358B1 (en) 2002-02-11 2013-07-03 Bayer HealthCare LLC Sorafenib tosylate for the treatment of diseases characterized by abnormal angiogenesis
WO2003068229A1 (en) 2002-02-11 2003-08-21 Bayer Pharmaceuticals Corporation Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors
CA2493701A1 (en) * 2002-07-25 2004-02-05 Pfizer Products Inc. Isothiazole derivatives useful as anticancer agents
EP1545519B1 (en) * 2002-08-19 2011-03-23 Pfizer Inc. Combination therapy for hyperproliferative diseases
US8796250B2 (en) 2003-05-20 2014-08-05 Bayer Healthcare Llc Diaryl ureas for diseases mediated by PDGFR
DE602004010407T2 (de) 2003-07-23 2008-10-16 Bayer Pharmaceuticals Corp., West Haven Fluorsubstituierter omega-carboxyaryldiphenylharnstoff zur behandlung und prävention von krankheiten und leiden
MXPA06004647A (es) * 2003-10-27 2006-06-27 Merck & Co Inc Sal antagonista de ccr-2.
WO2005061519A1 (en) 2003-12-19 2005-07-07 Takeda San Diego, Inc. Kinase inhibitors
WO2005102327A1 (en) * 2004-04-20 2005-11-03 Pfizer Products Inc. Dosage forms and methods of treatment using vegfr inhibitors
JP2007535565A (ja) 2004-04-30 2007-12-06 バイエル ファーマシューティカルス コーポレーション 癌の治療に有用な置換ピラゾリル尿素誘導体
TW200538104A (en) * 2004-05-17 2005-12-01 Pfizer Prod Inc Phenyl derivatives for the treatment of abnormal cell growth
EP1778669A2 (en) 2004-08-18 2007-05-02 Takeda San Diego, Inc. Kinase inhibitors
ATE479687T1 (de) 2004-10-15 2010-09-15 Takeda Pharmaceutical Kinaseinhibitoren
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
RS52205B2 (sr) 2006-06-16 2021-05-31 H Lundbeck A/S 1-[2-(2,4-dimetilfenilsulfanil)-fenil]piperazin kao jedinjenje sa kombinovanom aktivnošću ponovnog uzimanja serotonina, 5-ht3 i 5-ht1a, za tretman kognitivnih oštećenja
US7932390B2 (en) 2006-06-29 2011-04-26 Hoffman-La Roche Inc. Substituted thieno[3,2-C]pyridine carboxylic acid derivatives
US20100120717A1 (en) 2006-10-09 2010-05-13 Brown Jason W Kinase inhibitors
MX2010001636A (es) 2007-08-14 2010-03-15 Hoffmann La Roche Derivados de pirazolo[3,4-d]-pirimidina como agentes antiproliferativos.
WO2011073521A1 (en) 2009-12-15 2011-06-23 Petri Salven Methods for enriching adult-derived endothelial progenitor cells and uses thereof
CN103261225A (zh) 2010-07-23 2013-08-21 波士顿大学董事会 作为用于抑制病理性血管生成和肿瘤细胞侵袭力的治疗剂以及用于分子成像和靶向递送的抗DEspR抑制剂
SG11201507316UA (en) * 2013-03-14 2015-10-29 Panoptica Inc Ocular formulations for drug-delivery to the posterior segment of the eye
CA2958315A1 (en) * 2014-09-17 2016-03-24 Panoptica, Inc. Ocular formulations for drug-delivery and protection of the anterior segment of the eye
WO2024140850A1 (zh) * 2022-12-28 2024-07-04 苏州必扬医药科技有限公司 一种蛋白酪氨酸激酶抑制剂及其医药用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA60365C2 (uk) * 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця

Also Published As

Publication number Publication date
HUP0302553A3 (en) 2009-03-30
DK1337521T3 (da) 2007-01-29
HUP0302553A2 (hu) 2003-11-28
CZ20031315A3 (cs) 2004-04-14
HK1059085A1 (en) 2004-06-18
CA2430065A1 (en) 2002-06-06
GEP20053652B (en) 2005-11-10
ECSP034628A (es) 2003-07-25
BG107752A (bg) 2004-01-30
EA005859B1 (ru) 2005-06-30
HRP20030408A2 (en) 2003-08-31
PE20020591A1 (es) 2002-07-06
PA8533801A1 (es) 2002-10-31
US20020151573A1 (en) 2002-10-17
CR6963A (es) 2003-11-25
HN2001000268A (es) 2002-01-30
UY27039A1 (es) 2002-07-31
CA2430065C (en) 2008-05-20
CN1231474C (zh) 2005-12-14
WO2002044158A1 (en) 2002-06-06
JP4971946B2 (ja) 2012-07-11
CY1106240T1 (el) 2011-06-08
DE60123461T2 (de) 2007-02-15
SK5862003A3 (en) 2004-05-04
NZ525788A (en) 2004-11-26
JP2004514714A (ja) 2004-05-20
JP2008056692A (ja) 2008-03-13
TNSN01167A1 (fr) 2005-11-10
AU1420402A (en) 2002-06-11
US6831091B2 (en) 2004-12-14
IL155371A0 (en) 2003-11-23
SI1337521T1 (sl) 2006-12-31
MA26960A1 (fr) 2004-12-20
DE60123461D1 (de) 2006-11-09
TWI287542B (en) 2007-10-01
MXPA03004714A (es) 2003-08-19
EP1337521B1 (en) 2006-09-27
PT1337521E (pt) 2006-12-29
NO325187B1 (no) 2008-02-11
OA12532A (en) 2006-06-02
EP1337521A1 (en) 2003-08-27
NO20032388D0 (no) 2003-05-27
DOP2001000288A (es) 2002-12-15
YU36403A (sh) 2006-08-17
SV2002000748A (es) 2002-12-02
MY136686A (en) 2008-11-28
KR20050116401A (ko) 2005-12-12
AU2002214204B2 (en) 2007-05-24
AP2001002358A0 (en) 2001-12-31
CN1476439A (zh) 2004-02-18
PL362079A1 (en) 2004-10-18
ATE340786T1 (de) 2006-10-15
AR031512A1 (es) 2003-09-24
BR0115621A (pt) 2003-09-02
UA74221C2 (uk) 2005-11-15
ZA200303341B (en) 2004-04-30
KR20030059275A (ko) 2003-07-07
GT200100237A (es) 2002-07-03
NO20032388L (no) 2003-07-18
ES2271086T3 (es) 2007-04-16
EA200300424A1 (ru) 2003-10-30
EE200300247A (et) 2003-10-15

Similar Documents

Publication Publication Date Title
IS6788A (is) Sölt af ísóþíasól-4-karboxamíði og notkun þeirra sem efnisþættir gegn offjölgun (proliferation)
IS2529B (is) Nýjar spírótrísýklískar afleiður og notkun þeirra sem fosfódíesterasa-7-hindrar
DE60131315D1 (de) Beatmungskreislauf-Komponenten
IS6656A (is) Útskiptar kínasólínafleiður og notkun þeirra sem hemla
DK1202941T3 (da) Gipssammensætninger og beslægtede fremgangsmåder
DK1438306T3 (da) Derivater af UK-2A
DK1417175T3 (da) Substituerede dihydro-3-halo-1h-pyrazol-5-carboxylater og fremstillingog anvendelse heraf
EP1298180A4 (en) HYDROPHOBIC AND LIPOPHOBE COMPOSITION
IS6516A (is) Malónamsýrur og afleiður af þeim sem skjaldkirtilsviðtakabindlar
DK1122244T3 (da) Uracilforbindelser og anvendelse deraf
DE60129705D1 (de) Monoalkylglycerinäther stabile zusammensetzungen
IS6786A (is) Samsetning af GABA gerandefnum og sorbitól vetnissviftahindrum
NO20021786L (no) Skumdempningsfremgangsmåter og sammensetninger
NO20033854D0 (no) N-but-3-enyl-norbuprenorfin og fremgangsmåter for anvendelse
FI20010558L (fi) Kappaleiden paikannus
DE60215601D1 (de) Stabile Zusammensetzung
DK1274709T3 (da) Salte af bicykliske, N-acylerede imidazo-3-aminer og imidazo-5-aminer
IS2867B (is) Neublastín sem tengt er fjölliðu og aðferðir við notkun þess
DK1337228T3 (da) Sammensætninger til fjernelse af human cerumen
IS6620A (is) Nýr fjölgervingur V af tórasemíði
DK1372652T3 (da) Kombination af docetaxel og flavopiridol
FI20011778A0 (fi) Ryhmälähetyksen toteutus
DK1441746T3 (da) Sammens tning og fremgangsmode
DK1272456T3 (da) Angioneseinhibitorer på basis af hydrazid og alkoxyamid
NO20025135L (no) Antihypertensive midler og anvendelse