ES2151464T1 - Preparacion para aplicacion externa que comprende tranilast y procedimiento para producirla. - Google Patents
Preparacion para aplicacion externa que comprende tranilast y procedimiento para producirla.Info
- Publication number
- ES2151464T1 ES2151464T1 ES97902588T ES97902588T ES2151464T1 ES 2151464 T1 ES2151464 T1 ES 2151464T1 ES 97902588 T ES97902588 T ES 97902588T ES 97902588 T ES97902588 T ES 97902588T ES 2151464 T1 ES2151464 T1 ES 2151464T1
- Authority
- ES
- Spain
- Prior art keywords
- tranilast
- preparation
- external application
- procedure
- produce
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- NZHGWWWHIYHZNX-CSKARUKUSA-N tranilast Chemical compound C1=C(OC)C(OC)=CC=C1\C=C\C(=O)NC1=CC=CC=C1C(O)=O NZHGWWWHIYHZNX-CSKARUKUSA-N 0.000 title abstract 4
- 229960005342 tranilast Drugs 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000002270 dispersing agent Substances 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000012738 dissolution medium Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Una preparación para aplicación externa que contiene una base acuosa que comprende tranilast, su sal, o una de sus mezclas en calidad de ingrediente activo, conteniendo la preparación para aplicación externa tranilast, caracterizada porque dicha base acuosa comprende un medio de disolución para disolver el tranilast, un dispersante, un adyuvante de absorción, un adhesivo y/o un agente mantenedor de la forma, y agua, y/o el ingrediente activo está disuelto en dicho medio de disolución y dispersado en la base acuosa por medio de dicho dispersante.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4549396 | 1996-02-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2151464T1 true ES2151464T1 (es) | 2001-01-01 |
ES2151464T3 ES2151464T3 (es) | 2002-12-16 |
Family
ID=12720933
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97902588T Expired - Lifetime ES2151464T3 (es) | 1996-02-07 | 1997-02-06 | Preparacion para aplicacion externa que comprende tranilast y procedimiento para producirla. |
Country Status (12)
Country | Link |
---|---|
US (1) | US6239177B1 (es) |
EP (1) | EP0974350B1 (es) |
JP (1) | JP4154621B2 (es) |
KR (1) | KR100449939B1 (es) |
CN (1) | CN1081030C (es) |
AT (1) | ATE222759T1 (es) |
DE (2) | DE974350T1 (es) |
DK (1) | DK0974350T3 (es) |
ES (1) | ES2151464T3 (es) |
HK (1) | HK1018218A1 (es) |
PT (1) | PT974350E (es) |
WO (1) | WO1997028793A1 (es) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0894496A4 (en) * | 1996-02-15 | 2001-01-03 | Kissei Pharmaceutical | INHIBITOR OF NEOFORMATION OF BLOOD VESSELS |
JP4865958B2 (ja) * | 2001-05-23 | 2012-02-01 | 株式会社トクホン | 鎮痛抗炎症局所作用型の貼付剤 |
ATE497764T1 (de) * | 2002-11-05 | 2011-02-15 | Lead Chem Co Ltd | Perkutane absorptionszubereitungen mit 3-methyl-1-phenyl-2-pyrazolin-5-on |
JP2004307364A (ja) * | 2003-04-03 | 2004-11-04 | Yuutoku Yakuhin Kogyo Kk | 経皮吸収貼付剤 |
CA2546064C (en) * | 2003-11-12 | 2011-06-21 | Lead Chemical Co., Ltd. | Percutaneous absorption type cerebral protective agent |
US20050106230A1 (en) * | 2003-11-17 | 2005-05-19 | Young Janel E. | Drug-enhanced adhesion prevention |
US9066912B2 (en) * | 2003-11-17 | 2015-06-30 | Ethicon, Inc. | Drug-enhanced adhesion prevention |
US20050239892A1 (en) * | 2003-11-21 | 2005-10-27 | Trustees Of Tufts College | Therapeutic avenathramide compounds |
US7105263B2 (en) * | 2003-12-30 | 2006-09-12 | Samsung Electronics Company | Dry toner comprising encapsulated pigment, methods and uses |
JP4590224B2 (ja) * | 2004-07-20 | 2010-12-01 | 株式会社日本点眼薬研究所 | トラニラストまたは薬理学的に許容される塩を含有する懸濁性医薬組成物 |
JP4843824B2 (ja) * | 2004-08-18 | 2011-12-21 | 株式会社 メドレックス | 外用剤 |
US7473738B2 (en) * | 2004-09-30 | 2009-01-06 | Johnson & Johnson Vision Care, Inc. | Lactam polymer derivatives |
US20080009519A1 (en) * | 2004-11-17 | 2008-01-10 | Lawrence Steinman | Method of modulating t cell functioning |
ZA200704871B (en) * | 2004-11-17 | 2008-09-25 | Angiogen Pharmaceuticals Pty L | A method of modulating B cell functioning |
JP2007051089A (ja) * | 2005-08-18 | 2007-03-01 | Medorekkusu:Kk | 外用剤 |
EP1946753A4 (en) * | 2005-10-21 | 2009-05-13 | Medrx Co Ltd | PREPARATION FOR EXTERNAL APPLICATION COMPRISING A SALT OF A MASTOCYTE DEGRANULATION INHIBITOR COMPRISING A CARBOXYL GROUP WITH AN ORGANIC AMINE |
JP4959991B2 (ja) * | 2006-03-03 | 2012-06-27 | 株式会社日本点眼薬研究所 | トラニラストまたはその薬理学的に許容される塩を含有する懸濁性医薬組成物 |
AU2007271734B2 (en) | 2006-07-05 | 2012-03-29 | Certa Therapeutics Pty. Ltd. | Therapeutic compounds |
US8668703B2 (en) * | 2006-12-01 | 2014-03-11 | Wake Forest University Health Sciences | Medical devices incorporating collagen inhibitors |
EP2030617A1 (en) * | 2007-08-17 | 2009-03-04 | Sygnis Bioscience GmbH & Co. KG | Use of tranilast and derivatives thereof for the therapy of neurological conditions |
CN101152164B (zh) * | 2007-09-14 | 2011-04-06 | 李世荣 | 含有抗肥大细胞类药物的抗瘢痕外用贴膜及其制备方法 |
CN101152163B (zh) * | 2007-09-14 | 2010-05-26 | 李世荣 | 含有激素类药物的抗瘢痕外用贴膜及其制备方法 |
US9062076B2 (en) | 2009-10-22 | 2015-06-23 | Fibrotech Therapeutics Pty Ltd | Fused ring analogues of anti-fibrotic agents |
KR101593339B1 (ko) * | 2011-06-20 | 2016-02-11 | 히사미쓰 세이야꾸 가부시키가이샤 | 리도카인 함유 파프제 |
JP6096021B2 (ja) * | 2013-03-22 | 2017-03-15 | ファイテン株式会社 | 顎関節症用外用剤 |
JP6558117B2 (ja) * | 2014-08-19 | 2019-08-14 | 大正製薬株式会社 | 皮膚用剤 |
MA41266A (fr) * | 2014-12-22 | 2017-10-31 | Hisamitsu Pharmaceutical Co | Cataplasme |
EP3263097B1 (en) | 2015-02-24 | 2021-08-25 | Hisamitsu Pharmaceutical Co., Inc. | Adhesive skin poultice |
CN104784101A (zh) * | 2015-03-05 | 2015-07-22 | 中国药科大学制药有限公司 | 一种曲尼司特凝胶和软膏剂的处方及制备方法 |
KR101691472B1 (ko) | 2015-07-06 | 2017-01-09 | 이광재 | 배낭에 탈착이 용이한 스틱 걸이 |
EP3503884B1 (en) * | 2016-08-23 | 2021-07-21 | Neurim Pharmaceuticals Ltd. | Pharmaceutical composition for use in treating pruritus and/or itch |
CN110546133A (zh) | 2017-02-03 | 2019-12-06 | 塞尔塔治疗有限公司 | 抗纤维化化合物 |
CN108324724A (zh) * | 2018-04-10 | 2018-07-27 | 苏州芝宇生物科技有限公司 | 一种克立硼罗可溶性膜制剂的制法及其应用 |
CN113423394A (zh) | 2019-02-14 | 2021-09-21 | 久光制药株式会社 | 泥罨剂 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5124317A (en) * | 1985-08-02 | 1992-06-23 | Farmitalia Carlo Erba S.P.A. | Injectable ready-to-use solutions containing an antitumor anthracycline glycoside |
JPS62169723A (ja) * | 1986-01-22 | 1987-07-25 | Teisan Seiyaku Kk | 徐放化製剤 |
JPS63238024A (ja) * | 1987-03-26 | 1988-10-04 | Towa Yakuhin Kk | 水難溶性薬物を含有する外用ゲル組成物 |
EP0303445A1 (en) * | 1987-08-13 | 1989-02-15 | Walton S.A. | Clebopride transdermal patch |
US5446070A (en) * | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
US5719197A (en) * | 1988-03-04 | 1998-02-17 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
US5656286A (en) * | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
JPH01294620A (ja) * | 1988-05-19 | 1989-11-28 | Kissei Pharmaceut Co Ltd | 水溶液製剤およびその製造方法 |
JPH07116029B2 (ja) * | 1989-04-04 | 1995-12-13 | キッセイ薬品工業株式会社 | トラニラスト水溶液製剤 |
JPH0794378B2 (ja) | 1989-08-18 | 1995-10-11 | 久光製薬株式会社 | エアゾール剤 |
JP3243564B2 (ja) * | 1990-08-20 | 2002-01-07 | リードケミカル株式会社 | 外用貼付剤 |
JPH05178763A (ja) * | 1991-02-19 | 1993-07-20 | Nippon Saafuakutanto Kogyo Kk | 難溶解性薬物溶解剤組成物 |
JPH05163222A (ja) * | 1991-12-18 | 1993-06-29 | Kissei Pharmaceut Co Ltd | コラーゲン過剰合成疾患治療剤 |
US5989586A (en) * | 1992-10-05 | 1999-11-23 | Cygnus, Inc. | Two-phase matrix for sustained release drug delivery device |
JPH06128153A (ja) * | 1992-10-16 | 1994-05-10 | Kissei Pharmaceut Co Ltd | トラニラスト軟膏組成物およびその製造方法 |
AU667161B2 (en) * | 1993-04-28 | 1996-03-07 | Daiichi Pharmaceutical Co., Ltd. | Butyrophenone transdermal compositions |
PT698393E (pt) * | 1993-05-19 | 2002-10-31 | Hisamitsu Pharmaceutical Co | Agente de solubilizacao e preparacao para uso externo contendo o mesmo |
EP0709099A3 (en) * | 1994-09-28 | 1996-07-24 | Senju Pharma Co | Aqueous suspension for nasal administration containing cyclodextrin |
JPH08295624A (ja) * | 1995-04-26 | 1996-11-12 | Read Chem Kk | プラスター基剤、その製造方法、該基剤を使用した外用貼 付剤 |
FR2736048B1 (fr) * | 1995-06-27 | 1997-08-01 | Atochem Elf Sa | Synthese du difluoromethane |
CA2208332A1 (en) * | 1996-06-20 | 1997-12-20 | Hisamitsu Pharmaceuticals Co., Inc. | Drug administration composition for iontophoresis |
-
1997
- 1997-02-06 ES ES97902588T patent/ES2151464T3/es not_active Expired - Lifetime
- 1997-02-06 KR KR10-1998-0705983A patent/KR100449939B1/ko not_active IP Right Cessation
- 1997-02-06 WO PCT/JP1997/000283 patent/WO1997028793A1/ja active IP Right Grant
- 1997-02-06 US US09/117,658 patent/US6239177B1/en not_active Expired - Lifetime
- 1997-02-06 DK DK97902588T patent/DK0974350T3/da active
- 1997-02-06 PT PT97902588T patent/PT974350E/pt unknown
- 1997-02-06 CN CN97192132A patent/CN1081030C/zh not_active Expired - Fee Related
- 1997-02-06 EP EP97902588A patent/EP0974350B1/en not_active Expired - Lifetime
- 1997-02-06 AT AT97902588T patent/ATE222759T1/de not_active IP Right Cessation
- 1997-02-06 DE DE0974350T patent/DE974350T1/de active Pending
- 1997-02-06 JP JP52837697A patent/JP4154621B2/ja not_active Expired - Lifetime
- 1997-02-06 DE DE69715049T patent/DE69715049T2/de not_active Expired - Fee Related
-
1999
- 1999-07-29 HK HK99103272A patent/HK1018218A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP4154621B2 (ja) | 2008-09-24 |
DE69715049D1 (de) | 2002-10-02 |
KR19990082254A (ko) | 1999-11-25 |
CN1210462A (zh) | 1999-03-10 |
HK1018218A1 (en) | 1999-12-17 |
DE69715049T2 (de) | 2003-04-03 |
US6239177B1 (en) | 2001-05-29 |
CN1081030C (zh) | 2002-03-20 |
EP0974350A4 (en) | 2000-01-26 |
EP0974350A1 (en) | 2000-01-26 |
WO1997028793A1 (fr) | 1997-08-14 |
ES2151464T3 (es) | 2002-12-16 |
KR100449939B1 (ko) | 2004-11-20 |
DK0974350T3 (da) | 2002-11-25 |
DE974350T1 (de) | 2001-01-25 |
ATE222759T1 (de) | 2002-09-15 |
PT974350E (pt) | 2002-12-31 |
EP0974350B1 (en) | 2002-08-28 |
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