KR920014474A - 담석 붕괴용 제제 - Google Patents
담석 붕괴용 제제 Download PDFInfo
- Publication number
- KR920014474A KR920014474A KR1019920000806A KR920000806A KR920014474A KR 920014474 A KR920014474 A KR 920014474A KR 1019920000806 A KR1019920000806 A KR 1019920000806A KR 920000806 A KR920000806 A KR 920000806A KR 920014474 A KR920014474 A KR 920014474A
- Authority
- KR
- South Korea
- Prior art keywords
- aqueous solution
- alkali metal
- formulation according
- metal carbonate
- acetylcysteine
- Prior art date
Links
- 208000001130 gallstones Diseases 0.000 title claims abstract 6
- 238000002360 preparation method Methods 0.000 title claims 2
- 229910000288 alkali metal carbonate Inorganic materials 0.000 claims abstract 8
- 150000008041 alkali metal carbonates Chemical class 0.000 claims abstract 8
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 claims abstract 5
- 229960004308 acetylcysteine Drugs 0.000 claims abstract 5
- 201000001883 cholelithiasis Diseases 0.000 claims abstract 3
- 239000003795 chemical substances by application Substances 0.000 claims abstract 2
- 229910000028 potassium bicarbonate Inorganic materials 0.000 claims abstract 2
- 235000015497 potassium bicarbonate Nutrition 0.000 claims abstract 2
- 239000011736 potassium bicarbonate Substances 0.000 claims abstract 2
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 claims abstract 2
- 239000007864 aqueous solution Substances 0.000 claims 8
- 238000009472 formulation Methods 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 7
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 claims 2
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical group [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims 1
- 239000012153 distilled water Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229910000027 potassium carbonate Inorganic materials 0.000 claims 1
- 235000011181 potassium carbonates Nutrition 0.000 claims 1
- 229910000029 sodium carbonate Inorganic materials 0.000 claims 1
- 235000017550 sodium carbonate Nutrition 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 229940086066 potassium hydrogencarbonate Drugs 0.000 abstract 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
- UIIMBOGNXHQVGW-UHFFFAOYSA-M sodium bicarbonate Substances [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Lubricants (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (9)
- 알칼리금속 카르보네이트 또는 알칼리금속 카르보네이트와 N-아세틸시스테인의 조합을 함유한 수용액을 포함하는 담석 붕괴용 제제.
- 제1항에 있어서, 알칼리금속 카르보네이트가 탄산수소화나트륨, 탄산수소화칼륨, 탄산나트륨 또는 탄산칼륨제인 제제.
- 제1항에 있어서, 알칼리금속 카르보네이트를 수용액중 1∼30%(w/v)의 양으로 함유하는 제제.
- 제3항에 있어서, 알칼리금속 카르보네이트를 수용액중 5∼20%(w/v)의 양으로 함유하는 제제.
- 제1항에 있어서, N-아세틸시스테인이 수용액중 5∼30%(w/v)의 양으로 함유하는 제제.
- 제5항에 있어서, N-아세틸시스테인이 수용액중 10∼25%(w/v)의 양으로 함유하는 제제.
- 제1항에 있어서, 수용액의 pH가 7∼10의 범위인 제제.
- 제1항에 있어서, 수용액의 매질이 증류수인 제제.
- 담석 보유 환자에게, 알칼리금속 카르보네이트 또는 알칼리금속 카르보네이트와 N-아세틸시스테인의 조합을 함유한 수용액을 포함하는 담석 붕괴용 제제의 유효량을 투여하는 것으로 이루어진 담석증 치료방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP91-25596 | 1991-01-26 | ||
| JP2559691 | 1991-01-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR920014474A true KR920014474A (ko) | 1992-08-25 |
Family
ID=12170291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019920000806A KR920014474A (ko) | 1991-01-26 | 1992-01-21 | 담석 붕괴용 제제 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5441748A (ko) |
| EP (1) | EP0497724B1 (ko) |
| JP (1) | JPH0558900A (ko) |
| KR (1) | KR920014474A (ko) |
| AT (1) | ATE135915T1 (ko) |
| CA (1) | CA2059977A1 (ko) |
| DE (1) | DE69209335T2 (ko) |
| DK (1) | DK0497724T3 (ko) |
| ES (1) | ES2084971T3 (ko) |
| GR (1) | GR3020175T3 (ko) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5593688A (en) * | 1993-06-25 | 1997-01-14 | Nexstar Pharmaceuticals, Inc. | Liposomal targeting of ischemic tissue |
| AU7024094A (en) * | 1993-08-16 | 1995-02-23 | Senju Pharmaceutical Co., Ltd. | A bile duct deterging composition and a method for deterging the bile duct |
| WO2002030432A1 (en) * | 2000-06-23 | 2002-04-18 | Cambridgemed, Inc | Agent for reduction of scar formation by using wound alkalinization |
| US20050142208A1 (en) | 2002-05-09 | 2005-06-30 | Won Min Yoo | Pharmceutical composition for treatment of wounds conntaining blood plasma or serum |
| US8148356B2 (en) | 2005-08-24 | 2012-04-03 | Cumberland Pharmaceuticals, Inc. | Acetylcysteine composition and uses therefor |
| US9615601B2 (en) | 2005-10-04 | 2017-04-11 | Jimmyash Llc | Process for the controlled introduction of oil into food products |
| ES2603406T3 (es) | 2005-10-04 | 2017-02-27 | Jimmyash Llc | Procedimientos de producción de productos alimenticios de aperitivo y productos así preparados |
| EP1933648B1 (en) | 2005-10-04 | 2018-03-28 | JimmyAsh LLC | Fried food products having reduced fat content |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4451454A (en) * | 1981-06-16 | 1984-05-29 | Wong Dennis W | Prophylaxis and treatment of thromboembolic disorders in man and in warm-blooded animals with bicarbonate salts of alkali metals |
| DE3173007D1 (en) * | 1981-09-14 | 1986-01-02 | Olima Holding Ag | Pharmaceutical oral dosage forms of an active agent capable of forming or releasing bicarbonate ions |
| DD268864A1 (de) * | 1985-09-02 | 1989-06-14 | Karl Marx Uni Buero Fuer Neuer | Verfahren zur herstellung von mitteln fuer parenterale ernaehrung |
| CH667590A5 (it) * | 1986-07-24 | 1988-10-31 | Inpharzam Int Sa | Composizione farmaceutica effervescente idrosolubile contenente n-acetil-cisteina. . |
| DE3739401A1 (de) * | 1987-11-20 | 1989-06-01 | U Prof Dr Med Leuschner | Pharmazeutische zubereitung zur cholelitholyse (aufloesung von gallensteinen) |
-
1992
- 1992-01-21 AT AT92610005T patent/ATE135915T1/de not_active IP Right Cessation
- 1992-01-21 EP EP92610005A patent/EP0497724B1/en not_active Expired - Lifetime
- 1992-01-21 DE DE69209335T patent/DE69209335T2/de not_active Expired - Fee Related
- 1992-01-21 ES ES92610005T patent/ES2084971T3/es not_active Expired - Lifetime
- 1992-01-21 KR KR1019920000806A patent/KR920014474A/ko not_active Application Discontinuation
- 1992-01-21 DK DK92610005.8T patent/DK0497724T3/da active
- 1992-01-24 JP JP4011218A patent/JPH0558900A/ja not_active Withdrawn
- 1992-01-24 CA CA002059977A patent/CA2059977A1/en not_active Abandoned
-
1993
- 1993-11-10 US US08/150,252 patent/US5441748A/en not_active Expired - Fee Related
-
1996
- 1996-06-06 GR GR960401536T patent/GR3020175T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0497724B1 (en) | 1996-03-27 |
| DK0497724T3 (da) | 1996-04-29 |
| DE69209335T2 (de) | 1996-08-29 |
| ATE135915T1 (de) | 1996-04-15 |
| DE69209335D1 (de) | 1996-05-02 |
| CA2059977A1 (en) | 1992-07-27 |
| ES2084971T3 (es) | 1996-05-16 |
| GR3020175T3 (en) | 1996-09-30 |
| US5441748A (en) | 1995-08-15 |
| EP0497724A1 (en) | 1992-08-05 |
| JPH0558900A (ja) | 1993-03-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| E902 | Notification of reason for refusal | ||
| E601 | Decision to refuse application |