AR033796A1 - Composicion farmaceutica - Google Patents
Composicion farmaceuticaInfo
- Publication number
- AR033796A1 AR033796A1 ARP000103325A ARP000103325A AR033796A1 AR 033796 A1 AR033796 A1 AR 033796A1 AR P000103325 A ARP000103325 A AR P000103325A AR P000103325 A ARP000103325 A AR P000103325A AR 033796 A1 AR033796 A1 AR 033796A1
- Authority
- AR
- Argentina
- Prior art keywords
- pharmaceutical composition
- entacapone
- carbidopa
- levodopa
- sugar
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Abstract
Una composición farmacéutica, en especial con una composición sólida oral, que comprende cantidades farmacéuticamente efectivas de entacapone, levodopa y carbidopa o de sus sales o hidratos farmacéuticamente aceptables y un excipiente farmacéuticamente aceptable, en donde el excipiente es un alcohol de azúcar o almidón o un alcohol de azúcar y almidón. El entacapone, la levodopa y la carbidopa son útiles para tratar el mal de Parkinson
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI991485A FI109453B (fi) | 1999-06-30 | 1999-06-30 | Farmaseuttinen koostumus |
Publications (1)
Publication Number | Publication Date |
---|---|
AR033796A1 true AR033796A1 (es) | 2004-01-07 |
Family
ID=8554988
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000103325A AR033796A1 (es) | 1999-06-30 | 2000-06-29 | Composicion farmaceutica |
Country Status (42)
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI109453B (fi) * | 1999-06-30 | 2002-08-15 | Orion Yhtymae Oyj | Farmaseuttinen koostumus |
US7094427B2 (en) * | 2002-05-29 | 2006-08-22 | Impax Laboratories, Inc. | Combination immediate release controlled release levodopa/carbidopa dosage forms |
US20030224045A1 (en) * | 2002-05-29 | 2003-12-04 | Chien-Hsuan Han | Combination immediate release sustained release levodopa/carbidopa dosage forms |
US20060013875A1 (en) * | 2002-05-29 | 2006-01-19 | Impax Laboratories, Inc. | Combination immediate release controlled release levodopa/carbidopa dosage forms |
US20040166159A1 (en) * | 2002-05-29 | 2004-08-26 | Chien-Hsuan Han | Pharmaceutical dosage forms having immediate and controlled release properties that contain an aromatic amino acid decarboxylase inhibitor and levodopa |
US20050147670A1 (en) * | 2002-05-29 | 2005-07-07 | Impax Laboratories Inc. | Oral disintegrating dosage forms |
US20040006072A1 (en) * | 2002-06-25 | 2004-01-08 | Franz Robert M. | Sustained-release alprazolam composition |
EP1560569A4 (en) * | 2002-10-11 | 2006-03-22 | Depomed Dev Ltd | GASTRORETENTIVE LEVODOPA DELIVERY FORM |
AR044007A1 (es) | 2003-04-11 | 2005-08-24 | Newron Pharmaceuticals Inc | Metodos para el tratamiento de la enfermedad de parkinson |
EP1588704A1 (en) | 2004-04-22 | 2005-10-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders |
SE0401842D0 (sv) * | 2004-07-12 | 2004-07-12 | Dizlin Medical Design Ab | Infusion and injection solution of levodopa |
US20060241183A1 (en) * | 2004-09-28 | 2006-10-26 | Farouk Karoum | Compositions and methods of using D-DOPA to treat Parkinson's disease |
JP2008519811A (ja) | 2004-11-10 | 2008-06-12 | オリオン コーポレーション | 下肢静止不能症候群の治療 |
US20080187590A1 (en) | 2005-06-08 | 2008-08-07 | Kari Vahervuo | Oral Dosage Form |
AU2012216377C1 (en) * | 2005-06-08 | 2013-10-10 | Orion Corporation | Oral dosage form |
EP1901720A2 (en) * | 2005-06-23 | 2008-03-26 | Spherics, Inc. | Improved dosage forms for movement disorder treatment |
MY148644A (en) | 2005-07-18 | 2013-05-15 | Orion Corp | New pharmaceutical compounds |
AU2006272978B2 (en) | 2005-07-26 | 2012-06-07 | Bial - Portela & Ca, S.A. | Nitrocatechol derivatives as COMT inhibitors |
WO2007016190A2 (en) * | 2005-07-28 | 2007-02-08 | Duke University | Antiparkinsonian action of phenylisopropylamines |
EP1948153A2 (en) * | 2005-09-21 | 2008-07-30 | Orion Corporation | Treatment of symptoms of parkinson`s disease |
WO2007056570A2 (en) * | 2005-11-07 | 2007-05-18 | Teva Pharmaceutical Industries Ltd. | Levodopa compositions |
US8772346B2 (en) * | 2005-11-09 | 2014-07-08 | Torrent Pharmaceuticals Limited | Pharmaceutical composition |
GB2429645A (en) * | 2006-03-10 | 2007-03-07 | Sekhsaria Chemicals Ltd | Solid pharmaceutical composition comprising a COMT inhibitor, a starch and a wetting agent |
CN100384411C (zh) * | 2006-03-17 | 2008-04-30 | 北京科信必成医药科技发展有限公司 | 卡左双多巴口腔崩解片 |
WO2007113371A1 (en) * | 2006-03-31 | 2007-10-11 | Iprbox Oy | Pharmaceutical composition and preparation method thereof |
EP1845097A1 (en) | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazole derivatives as COMT inhibitors |
EP1870097A1 (en) * | 2006-06-15 | 2007-12-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of cognitive disorders |
US8106056B2 (en) * | 2006-06-16 | 2012-01-31 | Solvay Pharmaceuticals B.V. | Combination preparations comprising bifeprunox and a dopamine agonist |
US20080131492A1 (en) * | 2006-06-23 | 2008-06-05 | Spherics, Inc. | Dosage forms for movement disorder treatment |
EP2104424A4 (en) | 2006-10-30 | 2011-06-15 | Wockhardt Research Center | PHARMACEUTICAL COMPOSITIONS COMPRISING ENTACAPONE, LEVODOPA, AND CARBIDOPA |
WO2008079404A2 (en) * | 2006-12-22 | 2008-07-03 | Combinatorx, Incorporated | Pharmaceutical compositions for treatment of parkinson's disease and related disorders |
WO2008081268A2 (en) * | 2006-12-27 | 2008-07-10 | Wockhardt Research Centre | Pharmaceutical compositions of entacapone |
EP1946756A1 (en) * | 2007-01-17 | 2008-07-23 | Revotar Biopharmaceuticals AG | Use of entacapone in cosmetic, dermatological and pharmaceutical compositions |
RU2518483C2 (ru) | 2007-01-31 | 2014-06-10 | Биал-Портела Энд Ка, С.А. | Режим дозирования ингибиторов комт |
US20110171275A1 (en) * | 2007-08-20 | 2011-07-14 | Team Academy Of Pharmaceutical Science | Gastroretentive drug delivery system, preparation method and use thereof |
US8728517B2 (en) * | 2008-02-06 | 2014-05-20 | Wockhardt Ltd. | Pharmaceutical compositions of entacapone co-micronized with sugar alcohols |
ATE510537T1 (de) * | 2008-02-06 | 2011-06-15 | Wockhardt Research Center | Pharmazeutische zusammensetzungen von entacapon, levodopa und carbidopa mit verbesserter bioverfügbarkeit |
JP2011514380A (ja) | 2008-03-17 | 2011-05-06 | バイアル−ポルテラ アンド シーエー,エス.エー. | 5−[3−(2,5−ジクロロ−4,6−ジメチル−1−オキシ−ピリジン−3−イル)[1,2,4]オキサジアゾール−5−イル]−3−ニトロベンゼン−1,2−ジオールの結晶形 |
CN102170870A (zh) * | 2008-08-22 | 2011-08-31 | 沃克哈特研究中心 | 恩他卡朋或其盐的缓释药物组合物 |
NZ591328A (en) * | 2008-08-22 | 2012-11-30 | Wockhardt Research Center | Single unit oral dose pharmaceutical composition comprising levodopa, carbidopa and entacapone or salts thereof |
TR200806646A2 (tr) * | 2008-09-03 | 2009-06-22 | Dr. F. Fri̇k İlaç San. Ve Ti̇c. A.Ş. | Entakapon, levodopa ve karbidoba içeren farmasötik kombinasyonlar |
EP2233131A1 (en) | 2009-03-23 | 2010-09-29 | Laboratorios Lesvi, S.L. | Pharmaceutical composition containing levodopa, entacapone and carbidopa |
BRPI1014865B1 (pt) | 2009-04-01 | 2020-03-17 | Bial - Portela & C.A., S.A. | Composição que compreende grânulos compreendendo 2,5- dicloro- 3- (5- (3,4- dihidróxi- 5- nitrofenil)- 1,2,4- oxadiazol- 3- il)- 4,6- dimetilpiridina 1- óxido e formulação farmacêutica |
KR101709904B1 (ko) * | 2009-05-19 | 2017-02-23 | 뉴로덤 엘티디 | Dopa 데카르복실라제 억제제의 연속투여용 조성물 |
US9750702B2 (en) | 2009-12-25 | 2017-09-05 | Innopharmax, Inc. | Pharmaceutical composition for treating parkinson's disease and preparation method thereof |
EA026419B1 (ru) * | 2010-03-04 | 2017-04-28 | Орион Корпорейшн | Применение леводопы, карбидопы и энтакапона для лечения болезни паркинсона |
DE102010023828A1 (de) | 2010-06-15 | 2011-12-15 | IIP - Institut für industrielle Pharmazie, Forschungs- und Entwicklungsgesellschaft mbH | Pharmazeutisches Präparat, welches Entacapon, Levodopa und Carbidopa enthält |
BR112013011685B1 (pt) * | 2010-11-15 | 2022-03-03 | Neuroderm Ltd | Composição líquida farmaceuticamente aceitável e emplastro transdérmico |
US20140045900A1 (en) | 2011-02-11 | 2014-02-13 | Bial-Portela & Ca, S.A. | Administration regime for nitrocatechols |
EP2508174A1 (en) | 2011-04-06 | 2012-10-10 | Ljiljana Sovic Brkicic | Pharmaceutical composition |
WO2012147099A1 (en) | 2011-04-25 | 2012-11-01 | Suven Nishtaa Pharma Pvt. Ltd. | Pharmaceutical compositions of levodopa, carbidopa and entacapone |
US20140120166A1 (en) * | 2011-04-26 | 2014-05-01 | Innopharmax, Inc. | Composition of entacopone |
SI2791134T1 (sl) | 2011-12-13 | 2020-01-31 | Bial - Portela & Ca S.A. | Kemična spojina, ki je uporabna kot vmesna oblika za pripravo inhibitorja katehol-o-metiltransferaze |
TR201204839A2 (tr) * | 2012-04-25 | 2012-12-21 | Ali̇ Rai̇f İlaç Sanayi̇ A.Ş. | Uzatılmış salım sağlayan levodopa karbıdopa entakapon içeren tablet formülasyonu. |
ES2715028T3 (es) | 2012-06-05 | 2019-05-31 | Neuroderm Ltd | Composiciones que comprenden apomorfina y ácidos orgánicos y sus usos |
BR112015022390A8 (pt) * | 2013-03-13 | 2019-11-26 | Neuroderm Ltd | uso de carbidopa, levodopa e um inibidor de comt para a preparação de uma composição para tratamento de doença de parkinson |
EP2799065A1 (en) * | 2013-04-30 | 2014-11-05 | Deva Holding Anonim Sirketi | Levodopa carbidopa entacapone pharmaceutical formulations |
US10987313B2 (en) | 2013-10-07 | 2021-04-27 | Impax Laboratories, Llc | Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof |
EP3782614A1 (en) | 2013-10-07 | 2021-02-24 | Impax Laboratories, LLC | Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof |
US10258585B2 (en) | 2014-03-13 | 2019-04-16 | Neuroderm, Ltd. | DOPA decarboxylase inhibitor compositions |
PL3116475T3 (pl) | 2014-03-13 | 2021-02-08 | Neuroderm Ltd | Kompozycje inhibitora dekarboksylazy dopa |
PT3782617T (pt) | 2014-09-04 | 2024-02-29 | Lobsor Pharmaceuticals Ab | Composições farmacêuticas de gel compreendendo levodopa, carbidopa e entacapona |
RU2017120184A (ru) | 2014-11-28 | 2018-12-28 | БИАЛ - ПОРТЕЛА ЭНД Ка, С.А. | Лекарства для замедления течения болезни паркинсона |
EP3236957A1 (en) | 2014-12-23 | 2017-11-01 | Pharmathen S.A. | Levodopa/carbidopa/entacapone pharmaceutical preparation and method for preparing the same |
WO2017039525A1 (en) | 2015-09-04 | 2017-03-09 | Lobsor Pharmaceuticals Aktiebolag | Method of treating a dopamine related disorder in a subject by administering levodopa, in combination with a dopamine decarboxylase inhibitor and a catechol-o-methyltransferase inhibitor |
EA036784B1 (ru) | 2016-08-18 | 2020-12-21 | Илько Илач Санайи Ве Тиджарет Аноним Ширкети | Таблетированный состав с улучшенным профилем растворения для лечения болезни паркинсона |
WO2019145773A1 (en) | 2017-12-15 | 2019-08-01 | Nos Life Sciences Corporation | Liposomal-encapsulated formulations |
KR20200136008A (ko) | 2018-03-23 | 2020-12-04 | 롭서 파마슈티컬스 악티에볼라그 | 신경퇴행성 장애의 치료를 위한 약제학적 조성물의 연속 투여 |
US11331293B1 (en) | 2020-11-17 | 2022-05-17 | Neuroderm, Ltd. | Method for treatment of Parkinson's disease |
US11213502B1 (en) | 2020-11-17 | 2022-01-04 | Neuroderm, Ltd. | Method for treatment of parkinson's disease |
US11844754B2 (en) | 2020-11-17 | 2023-12-19 | Neuroderm, Ltd. | Methods for treatment of Parkinson's disease |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4190672A (en) | 1978-09-01 | 1980-02-26 | Stanley Fahn | Method and compositions of treating Parkinsonisms with levodopa and 3',4'-dihydroxy-2-methylisopropiophenone |
GB8521350D0 (en) * | 1985-08-28 | 1985-10-02 | Euro Celtique Sa | Analgesic composition |
US5236952A (en) | 1986-03-11 | 1993-08-17 | Hoffmann-La Roche Inc. | Catechol derivatives |
NZ220599A (en) * | 1986-06-16 | 1990-10-26 | Merck & Co Inc | Controlled release oral dosage formulation of carbidopa and levodopa |
US5283352A (en) | 1986-11-28 | 1994-02-01 | Orion-Yhtyma Oy | Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same |
DE4101873C2 (de) * | 1991-01-23 | 1993-12-09 | Isis Pharma Gmbh | Peroral applizierbare Arzneiform zur Behandlung zentraler Dopaminmangelzustände |
US5888534A (en) | 1995-06-13 | 1999-03-30 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
GB2321190B (en) * | 1997-01-16 | 2000-09-20 | Britannia Pharmaceuticals Ltd | Pharmaceutical composition |
US6599530B2 (en) | 1998-09-14 | 2003-07-29 | Orion Corporation | Oral compacted composition comprising catechol derivatives |
FI109453B (fi) | 1999-06-30 | 2002-08-15 | Orion Yhtymae Oyj | Farmaseuttinen koostumus |
-
1999
- 1999-06-30 FI FI991485A patent/FI109453B/fi not_active IP Right Cessation
-
2000
- 2000-05-26 TW TW089110218A patent/TWI241187B/zh not_active IP Right Cessation
- 2000-06-27 PE PE2000000641A patent/PE20010399A1/es not_active IP Right Cessation
- 2000-06-28 IT IT2000MI001450A patent/ITMI20001450A1/it unknown
- 2000-06-29 CO CO00048944A patent/CO5180579A1/es active IP Right Grant
- 2000-06-29 BR BRPI0011867A patent/BRPI0011867B8/pt unknown
- 2000-06-29 MX MXPA01013167A patent/MXPA01013167A/es active IP Right Grant
- 2000-06-29 SK SK1923-2001A patent/SK286451B6/sk not_active IP Right Cessation
- 2000-06-29 GE GE4619A patent/GEP20043314B/en unknown
- 2000-06-29 MY MYPI20002972A patent/MY127685A/en unknown
- 2000-06-29 KR KR1020017015737A patent/KR100905428B1/ko active IP Right Grant
- 2000-06-29 PT PT00944070T patent/PT1189608E/pt unknown
- 2000-06-29 CA CA002378469A patent/CA2378469C/en not_active Expired - Lifetime
- 2000-06-29 EP EP00944070A patent/EP1189608B1/en not_active Expired - Lifetime
- 2000-06-29 WO PCT/FI2000/000593 patent/WO2001001984A1/en active Application Filing
- 2000-06-29 JP JP2001507476A patent/JP4204783B2/ja not_active Expired - Lifetime
- 2000-06-29 AU AU58306/00A patent/AU765932B2/en not_active Expired
- 2000-06-29 UA UA2002010771A patent/UA75047C2/uk unknown
- 2000-06-29 PL PL352775A patent/PL197818B1/pl unknown
- 2000-06-29 NZ NZ515780A patent/NZ515780A/en not_active IP Right Cessation
- 2000-06-29 ES ES00944070T patent/ES2203495T3/es not_active Expired - Lifetime
- 2000-06-29 SI SI200030190T patent/SI1189608T1/xx unknown
- 2000-06-29 US US09/605,529 patent/US6500867B1/en not_active Expired - Lifetime
- 2000-06-29 CZ CZ2011-885A patent/CZ304416B6/cs not_active IP Right Cessation
- 2000-06-29 DK DK00944070T patent/DK1189608T3/da active
- 2000-06-29 CN CNB008095868A patent/CN1168440C/zh not_active Expired - Lifetime
- 2000-06-29 EE EEP200100716A patent/EE05473B1/xx unknown
- 2000-06-29 BR BR0011867-2A patent/BR0011867A/pt not_active IP Right Cessation
- 2000-06-29 TR TR2001/03763T patent/TR200103763T2/xx unknown
- 2000-06-29 ME MEP-2008-863A patent/ME00520B/me unknown
- 2000-06-29 DE DE60004052T patent/DE60004052T2/de not_active Expired - Lifetime
- 2000-06-29 AT AT00944070T patent/ATE245417T1/de active
- 2000-06-29 AR ARP000103325A patent/AR033796A1/es unknown
- 2000-06-29 HU HU0202273A patent/HU230395B1/hu unknown
- 2000-06-29 RS YUP-925/01A patent/RS50368B/sr unknown
- 2000-06-29 EA EA200200106A patent/EA004503B1/ru not_active IP Right Cessation
- 2000-06-29 CZ CZ20014636A patent/CZ303010B6/cs not_active IP Right Cessation
- 2000-06-30 FR FR0008472A patent/FR2797587A1/fr not_active Withdrawn
-
2001
- 2001-11-29 ZA ZA200109868A patent/ZA200109868B/xx unknown
- 2001-11-29 IL IL146807A patent/IL146807A/en active IP Right Grant
- 2001-12-18 NO NO20016203A patent/NO330260B1/no not_active IP Right Cessation
- 2001-12-20 BG BG106251A patent/BG65364B1/bg unknown
-
2002
- 2002-01-29 HR HR20020088A patent/HRP20020088B1/xx not_active IP Right Cessation
- 2002-08-20 US US10/223,298 patent/US6797732B2/en not_active Expired - Lifetime
- 2002-11-29 HK HK02108609.4A patent/HK1047040B/zh not_active IP Right Cessation
-
2008
- 2008-03-12 JP JP2008063280A patent/JP4885896B2/ja not_active Expired - Lifetime
-
2011
- 2011-01-19 NO NO20110090A patent/NO20110090L/no unknown
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