PT1017681E - Derivados de hidrazono-benzazuleno composicoes farmaceuticas e intermediarios - Google Patents
Derivados de hidrazono-benzazuleno composicoes farmaceuticas e intermediariosInfo
- Publication number
- PT1017681E PT1017681E PT98945363T PT98945363T PT1017681E PT 1017681 E PT1017681 E PT 1017681E PT 98945363 T PT98945363 T PT 98945363T PT 98945363 T PT98945363 T PT 98945363T PT 1017681 E PT1017681 E PT 1017681E
- Authority
- PT
- Portugal
- Prior art keywords
- pharmaceutical
- intermediate compounds
- compounds
- formulawherein
- substituents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C333/02—Monothiocarbamic acids; Derivatives thereof
- C07C333/04—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/52—Nitrogen atoms not forming part of a nitro radical with hetero atoms directly attached to said nitrogen atoms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9711859A FR2768734B1 (fr) | 1997-09-24 | 1997-09-24 | Nouveaux composes tricycliques, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1017681E true PT1017681E (pt) | 2004-06-30 |
Family
ID=9511409
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98945363T PT1017681E (pt) | 1997-09-24 | 1998-09-23 | Derivados de hidrazono-benzazuleno composicoes farmaceuticas e intermediarios |
Country Status (11)
Country | Link |
---|---|
US (1) | US6277845B1 (pt) |
EP (1) | EP1017681B1 (pt) |
JP (1) | JP4493839B2 (pt) |
AT (1) | ATE236885T1 (pt) |
AU (1) | AU9270598A (pt) |
DE (1) | DE69813263T2 (pt) |
DK (1) | DK1017681T3 (pt) |
ES (1) | ES2192789T3 (pt) |
FR (1) | FR2768734B1 (pt) |
PT (1) | PT1017681E (pt) |
WO (1) | WO1999015507A1 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2768736B1 (fr) * | 1997-09-24 | 2000-05-26 | Roussel Uclaf | Nouveaux composes tricycliques, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant |
US6514964B1 (en) | 1999-09-27 | 2003-02-04 | Amgen Inc. | Fused cycloheptane and fused azacycloheptane compounds and their methods of use |
KR100861466B1 (ko) | 2001-04-24 | 2008-10-02 | 메르크 파텐트 게엠베하 | 항혈관형성제 및 TNFα를 이용한 병용 요법 |
JP2009523813A (ja) | 2006-01-18 | 2009-06-25 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 癌を治療するためにインテグリンのリガンドを使用する特異的な治療法 |
KR20090108713A (ko) | 2007-01-18 | 2009-10-16 | 메르크 파텐트 게엠베하 | 인테그린 리간드를 사용하는 암치료용 특이적 요법 및 의약 |
WO2010068371A2 (en) * | 2008-12-11 | 2010-06-17 | University Of Georgia Research Foundation, Inc. | Preparation of alkenes by mild thermolysis of sulfoxides |
NZ597339A (en) | 2009-05-25 | 2013-10-25 | Merck Patent Gmbh | Continuous administration of cilengitide in cancer treatments |
CN106572997A (zh) | 2014-05-30 | 2017-04-19 | 辉瑞公司 | 作为选择性雄激素受体调节剂的腈衍生物 |
WO2023275715A1 (en) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Metabolites of selective androgen receptor modulators |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH10504825A (ja) * | 1994-08-22 | 1998-05-12 | スミスクライン・ビーチャム・コーポレイション | 二環式化合物 |
FR2731217B1 (fr) * | 1995-03-03 | 1997-06-13 | Roussel Uclaf | Nouveaux derives tricycliques, leur preparation, leur application a la preparation de la colchicine et de la thiocolchicine optiquement actives ou racemiques et d'analogues ou derives et intermediaires |
GEP20012516B (en) * | 1996-03-20 | 2001-08-27 | Genentech Inc | Tricyclic Compounds Having Activity Specific for Integring, Particularly , avB3 Integrins, Method for Preparation the Same as Drugs and Pharmaceutical Composition Containing Same |
DE19629817A1 (de) * | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Imino-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
-
1997
- 1997-09-24 FR FR9711859A patent/FR2768734B1/fr not_active Expired - Lifetime
-
1998
- 1998-09-23 US US09/509,263 patent/US6277845B1/en not_active Expired - Lifetime
- 1998-09-23 EP EP98945363A patent/EP1017681B1/fr not_active Expired - Lifetime
- 1998-09-23 AT AT98945363T patent/ATE236885T1/de not_active IP Right Cessation
- 1998-09-23 PT PT98945363T patent/PT1017681E/pt unknown
- 1998-09-23 WO PCT/FR1998/002039 patent/WO1999015507A1/fr active IP Right Grant
- 1998-09-23 DK DK98945363T patent/DK1017681T3/da active
- 1998-09-23 ES ES98945363T patent/ES2192789T3/es not_active Expired - Lifetime
- 1998-09-23 AU AU92705/98A patent/AU9270598A/en not_active Abandoned
- 1998-09-23 DE DE69813263T patent/DE69813263T2/de not_active Expired - Lifetime
- 1998-09-23 JP JP2000512815A patent/JP4493839B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6277845B1 (en) | 2001-08-21 |
DK1017681T3 (da) | 2003-07-14 |
FR2768734B1 (fr) | 2000-01-28 |
ES2192789T3 (es) | 2003-10-16 |
JP2001517657A (ja) | 2001-10-09 |
FR2768734A1 (fr) | 1999-03-26 |
DE69813263D1 (de) | 2003-05-15 |
EP1017681A1 (fr) | 2000-07-12 |
ATE236885T1 (de) | 2003-04-15 |
JP4493839B2 (ja) | 2010-06-30 |
AU9270598A (en) | 1999-04-12 |
EP1017681B1 (fr) | 2003-04-09 |
DE69813263T2 (de) | 2004-01-29 |
WO1999015507A1 (fr) | 1999-04-01 |
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