RS50091B - Upotreba retigabina u lečenju neuropatskog bola - Google Patents
Upotreba retigabina u lečenju neuropatskog bolaInfo
- Publication number
- RS50091B RS50091B YUP-203/02A YUP20302A RS50091B RS 50091 B RS50091 B RS 50091B YU P20302 A YUP20302 A YU P20302A RS 50091 B RS50091 B RS 50091B
- Authority
- RS
- Serbia
- Prior art keywords
- treatment
- neuropathic pain
- retigabine
- prophylaxis
- manufacture
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Upotreba jedinjenja I ili njegovih farmaceutski upotrebljivih soli, za proizvodnju farmaceutskih proizvoda za profilaksu i lečenje neuropatskog bola. Prijava sadrži još 5 patentnih zahteva.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/406,135 US6117900A (en) | 1999-09-27 | 1999-09-27 | Use of retigabine for the treatment of neuropathic pain |
Publications (2)
Publication Number | Publication Date |
---|---|
YU20302A YU20302A (sh) | 2005-03-15 |
RS50091B true RS50091B (sr) | 2009-01-22 |
Family
ID=23606675
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YUP-203/02A RS50091B (sr) | 1999-09-27 | 2000-09-22 | Upotreba retigabina u lečenju neuropatskog bola |
Country Status (35)
Country | Link |
---|---|
US (1) | US6117900A (sr) |
EP (1) | EP1223927B1 (sr) |
JP (1) | JP2003510273A (sr) |
KR (1) | KR100730829B1 (sr) |
CN (2) | CN101444498A (sr) |
AR (1) | AR026163A1 (sr) |
AT (1) | ATE288748T1 (sr) |
AU (1) | AU777764B2 (sr) |
BG (1) | BG65795B1 (sr) |
BR (1) | BR0014293A (sr) |
CA (2) | CA2384504C (sr) |
CZ (1) | CZ295980B6 (sr) |
DE (1) | DE50009504D1 (sr) |
DK (1) | DK1223927T3 (sr) |
EE (1) | EE05073B1 (sr) |
ES (1) | ES2237461T3 (sr) |
HK (1) | HK1052471A1 (sr) |
HR (1) | HRP20020234A2 (sr) |
HU (1) | HUP0202853A3 (sr) |
IL (3) | IL148309A0 (sr) |
IS (1) | IS6303A (sr) |
MX (1) | MXPA02003179A (sr) |
NO (1) | NO329744B1 (sr) |
NZ (1) | NZ517616A (sr) |
PL (1) | PL200847B1 (sr) |
PT (1) | PT1223927E (sr) |
RS (1) | RS50091B (sr) |
RU (1) | RU2264813C2 (sr) |
SI (1) | SI1223927T1 (sr) |
SK (1) | SK286057B6 (sr) |
TR (1) | TR200200706T2 (sr) |
TW (1) | TWI257304B (sr) |
UA (1) | UA72550C2 (sr) |
WO (1) | WO2001022953A2 (sr) |
ZA (1) | ZA200202449B (sr) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1292307A2 (en) * | 2000-06-09 | 2003-03-19 | The Regents of The University of California | Method of treating pain using nalbuphine and opioid antagonists |
TWI287984B (en) | 2000-10-17 | 2007-10-11 | Wyeth Corp | Pharmaceutical composition for modulating bladder function |
US6589986B2 (en) * | 2000-12-20 | 2003-07-08 | Wyeth | Methods of treating anxiety disorders |
WO2002061075A1 (fr) * | 2001-02-01 | 2002-08-08 | Takeda Chemical Industries, Ltd. | Proteine de recepteur couple aux proteines g et adn correspondant |
US6855829B2 (en) | 2001-02-20 | 2005-02-15 | Bristol-Myers Squibb Company | 3-fluoro-2-oxindole modulators of KCNQ potassium channels and use thereof in treating migraine and mechanistically related disease |
AU2002338333A1 (en) * | 2001-04-04 | 2002-10-21 | Wyeth | Methods for treating hyperactive gastric motility |
JP2006503025A (ja) * | 2002-09-05 | 2006-01-26 | サイオス インク. | p38MAPキナーゼの抑制による疼痛治療 |
US20080039461A1 (en) * | 2002-09-05 | 2008-02-14 | Protter Andrew A | Treatment of pain by inhibition of p38 map kinase |
US7632866B2 (en) * | 2002-10-21 | 2009-12-15 | Ramot At Tel Aviv University | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators |
AU2003296954A1 (en) * | 2002-12-13 | 2004-07-09 | The Regents Of The University Of California | Analgesic combination comprising nalbuphine |
DK1578740T3 (da) * | 2002-12-27 | 2007-07-30 | Lundbeck & Co As H | 1,2,4-triaminobenzenderivater, der er egnede til behandling af lidelser i centralnervesystemet |
PL377221A1 (pl) * | 2002-12-27 | 2006-01-23 | H. Lundbeck A/S | Pochodne 1,2,4-triaminobenzenu |
EP1631546A1 (en) * | 2003-04-25 | 2006-03-08 | H. Lundbeck A/S | Sustituted indoline and indole derivatives |
US20050089559A1 (en) * | 2003-10-23 | 2005-04-28 | Istvan Szelenyi | Combinations of potassium channel openers and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains |
TWI357901B (en) | 2004-03-12 | 2012-02-11 | Lundbeck & Co As H | Substituted morpholine and thiomorpholine derivati |
AU2006220130B2 (en) | 2005-03-03 | 2011-07-28 | H. Lundbeck A/S | Substituted pyridine derivatives |
US7960436B2 (en) * | 2006-06-05 | 2011-06-14 | Valeant Pharmaceuticals International | Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators |
US20080045534A1 (en) * | 2006-08-18 | 2008-02-21 | Valeant Pharmaceuticals North America | Derivatives of 1,3-diamino benzene as potassium channel modulators |
PT2061465E (pt) * | 2006-08-23 | 2013-07-15 | Valeant Pharmaceuticals Int | Derivados de 4-(n-azacicloalquil)anilidas como moduladores do canal de potássio |
US8993593B2 (en) * | 2006-08-23 | 2015-03-31 | Valeant Pharmaceuticals International | N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators |
US8722929B2 (en) * | 2006-10-10 | 2014-05-13 | Valeant Pharmaceuticals International | N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators |
US8030518B2 (en) * | 2006-11-28 | 2011-10-04 | Valeant Pharmaceuticals International | 1,4 diamino bicyclic retigabine analogues as potassium channel modulators |
US8367684B2 (en) * | 2007-06-13 | 2013-02-05 | Valeant Pharmaceuticals International | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
US8563566B2 (en) * | 2007-08-01 | 2013-10-22 | Valeant Pharmaceuticals International | Naphthyridine derivatives as potassium channel modulators |
US7786146B2 (en) * | 2007-08-13 | 2010-08-31 | Valeant Pharmaceuticals International | Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators |
EP2203411B1 (en) | 2007-09-20 | 2016-01-06 | Ramot at Tel-Aviv University Ltd. | N-phenyl anthranilic acid derivatives and uses thereof |
WO2010009433A1 (en) * | 2008-07-18 | 2010-01-21 | Valeant Pharmaceuticals International | Modified release formulation and methods of use |
US20100323015A1 (en) * | 2008-07-18 | 2010-12-23 | Biljana Nadjsombati | Modified release formulation and methods of use |
US20100323016A1 (en) * | 2008-07-18 | 2010-12-23 | Biljana Nadjsombati | Modified release formulation and methods of use |
DE102009013612A1 (de) | 2009-03-17 | 2010-09-23 | Ratiopharm Gmbh | Retigabin-Tabletten, bevorzugt mit modifizierter Freisetzung |
DE102009013613A1 (de) | 2009-03-17 | 2010-09-23 | Ratiopharm Gmbh | Trockenverarbeitung von Retigabin |
DE102009013611A1 (de) | 2009-03-17 | 2010-09-23 | Ratiopharm Gmbh | Festes Retigabin in nicht-kristalliner Form |
IT1398282B1 (it) * | 2009-07-30 | 2013-02-22 | Difass S A Ora Farmapros S P A | Composizione comprendente acido alfa-lipoico e carnosina per il trattamento della sindrome dell arto fantasma |
US20110087650A1 (en) * | 2009-10-06 | 2011-04-14 | Johnson Controls Technology Company | Creation and use of causal relationship models in building management systems and applications |
TR201002473A2 (tr) * | 2010-03-31 | 2011-09-21 | Mustafa Nevzat �La� Sanay�� A.�. | Herpes zoster hastalığının bır opiat reseptör antagonist kullanılarak tedavi yöntemi. |
RU2446795C1 (ru) * | 2011-03-31 | 2012-04-10 | Федеральное государственное учреждение "Московский научно-исследовательский онкологический институт им. П.А. Герцена Министерства здравоохранения и социального развития Российской Федерации" ФГУ "МНИОИ им. П.А. Герцена "Минздравсоцразвития России" | Способ предотвращения фантомного болевого синдрома после ампутации конечностей |
CN102531966B (zh) * | 2011-12-23 | 2013-07-24 | 山东创新药物研发有限公司 | 瑞替加滨的晶型d及其制备方法 |
US20130310385A1 (en) | 2012-05-18 | 2013-11-21 | Gruenenthal Gmbh | Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants |
US9320725B2 (en) | 2012-05-18 | 2016-04-26 | Gruenenthal Gmbh | Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a gabapentinoid |
US9345689B2 (en) * | 2012-05-18 | 2016-05-24 | Gruenenthal Gmbh | Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N, N-dimethyl-4-phenyl-4,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and an anticonvulsant |
CN103271899A (zh) * | 2012-12-30 | 2013-09-04 | 北京阜康仁生物制药科技有限公司 | 瑞替加滨粉碎粒度在制剂中的应用 |
CN106176715A (zh) * | 2016-06-29 | 2016-12-07 | 青岛云天生物技术有限公司 | 一种神经病理性疼痛治疗用药物组合物及其用途 |
CN105919990A (zh) * | 2016-06-29 | 2016-09-07 | 青岛云天生物技术有限公司 | 用于预防和治疗神经病理性疼痛的药物组合物及其用途 |
WO2019014547A1 (en) | 2017-07-14 | 2019-01-17 | Texas Tech University System | FUNCTIONALIZED PYRIDINE CARBAMATES HAVING ENHANCED NEUROPROTECTOR ACTIVITY |
EP3694833A4 (en) | 2017-10-09 | 2021-06-30 | Ramot at Tel-Aviv University Ltd. | TRPV1 AND POTASIC IONIC CHANNEL MODULATORS AND THEIR USES |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4200259A1 (de) * | 1992-01-08 | 1993-07-15 | Asta Medica Ag | Neue 1,2,4-triaminobenzol-derivate und verfahren zu deren herstellung |
DE19539861A1 (de) * | 1995-10-26 | 1997-04-30 | Asta Medica Ag | Verwendung von 4-Amino-4-(4-fluorbenzylamino)-1-ethoxy-carbonylaminobenzen zur Prophylaxe und Behandlung der Folgen der akuten und chronischen zerebralen Minderdurchblutung sowie neurodegenerativer Erkrankungen |
GB9915414D0 (en) * | 1999-07-01 | 1999-09-01 | Glaxo Group Ltd | Medical use |
-
1999
- 1999-09-27 US US09/406,135 patent/US6117900A/en not_active Expired - Lifetime
-
2000
- 2000-09-21 TW TW089119495A patent/TWI257304B/zh not_active IP Right Cessation
- 2000-09-22 IL IL14830900A patent/IL148309A0/xx active IP Right Grant
- 2000-09-22 JP JP2001526165A patent/JP2003510273A/ja not_active Ceased
- 2000-09-22 CA CA002384504A patent/CA2384504C/en not_active Expired - Fee Related
- 2000-09-22 WO PCT/EP2000/009284 patent/WO2001022953A2/de active Application Filing
- 2000-09-22 SI SI200030641T patent/SI1223927T1/xx unknown
- 2000-09-22 CA CA002659048A patent/CA2659048A1/en not_active Abandoned
- 2000-09-22 AT AT00969283T patent/ATE288748T1/de active
- 2000-09-22 CZ CZ2002989A patent/CZ295980B6/cs not_active IP Right Cessation
- 2000-09-22 BR BR0014293-0A patent/BR0014293A/pt not_active Application Discontinuation
- 2000-09-22 MX MXPA02003179A patent/MXPA02003179A/es active IP Right Grant
- 2000-09-22 AU AU79061/00A patent/AU777764B2/en not_active Ceased
- 2000-09-22 PT PT00969283T patent/PT1223927E/pt unknown
- 2000-09-22 UA UA2002043557A patent/UA72550C2/uk unknown
- 2000-09-22 SK SK292-2002A patent/SK286057B6/sk not_active IP Right Cessation
- 2000-09-22 KR KR1020027003903A patent/KR100730829B1/ko not_active IP Right Cessation
- 2000-09-22 RU RU2002109240/15A patent/RU2264813C2/ru not_active IP Right Cessation
- 2000-09-22 NZ NZ517616A patent/NZ517616A/xx not_active IP Right Cessation
- 2000-09-22 TR TR2002/00706T patent/TR200200706T2/xx unknown
- 2000-09-22 CN CNA2008101752753A patent/CN101444498A/zh active Pending
- 2000-09-22 PL PL353393A patent/PL200847B1/pl not_active IP Right Cessation
- 2000-09-22 RS YUP-203/02A patent/RS50091B/sr unknown
- 2000-09-22 DE DE50009504T patent/DE50009504D1/de not_active Expired - Lifetime
- 2000-09-22 DK DK00969283T patent/DK1223927T3/da active
- 2000-09-22 HU HU0202853A patent/HUP0202853A3/hu unknown
- 2000-09-22 EP EP00969283A patent/EP1223927B1/de not_active Expired - Lifetime
- 2000-09-22 CN CNB008133042A patent/CN100522155C/zh not_active Expired - Fee Related
- 2000-09-22 ES ES00969283T patent/ES2237461T3/es not_active Expired - Lifetime
- 2000-09-22 EE EEP200200145A patent/EE05073B1/xx not_active IP Right Cessation
- 2000-09-26 AR ARP000105028A patent/AR026163A1/es unknown
-
2002
- 2002-02-21 IL IL148309A patent/IL148309A/en not_active IP Right Cessation
- 2002-02-27 BG BG106450A patent/BG65795B1/bg unknown
- 2002-03-18 HR HR20020234A patent/HRP20020234A2/hr not_active Application Discontinuation
- 2002-03-18 IS IS6303A patent/IS6303A/is unknown
- 2002-03-21 NO NO20021418A patent/NO329744B1/no not_active IP Right Cessation
- 2002-03-27 ZA ZA200202449A patent/ZA200202449B/xx unknown
-
2003
- 2003-07-08 HK HK03104879.5A patent/HK1052471A1/zh unknown
-
2007
- 2007-10-30 IL IL187030A patent/IL187030A/en active IP Right Grant
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