AP249A - Anti-viral compounds. - Google Patents

Anti-viral compounds. Download PDF

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Publication number
AP249A
AP249A APAP/P/1991/000253A AP9100253A AP249A AP 249 A AP249 A AP 249A AP 9100253 A AP9100253 A AP 9100253A AP 249 A AP249 A AP 249A
Authority
AP
ARIPO
Prior art keywords
compound
formula
acetamido
group
glycero
Prior art date
Application number
APAP/P/1991/000253A
Other languages
English (en)
Other versions
AP9100253A0 (en
Inventor
Itzstein Laurence Mark Von
Wen-Yang Wu
Tho Van Phan
Basil Danylec
Betty Jin
Original Assignee
Biota Scient Management Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biota Scient Management Pty Ltd filed Critical Biota Scient Management Pty Ltd
Publication of AP9100253A0 publication Critical patent/AP9100253A0/xx
Application granted granted Critical
Publication of AP249A publication Critical patent/AP249A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30Oxygen atoms, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
APAP/P/1991/000253A 1990-04-24 1991-04-23 Anti-viral compounds. AP249A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPJ980090 1990-04-24
AUPK289690 1990-10-19
AUPK453791 1991-02-11

Publications (2)

Publication Number Publication Date
AP9100253A0 AP9100253A0 (en) 1991-04-30
AP249A true AP249A (en) 1993-03-17

Family

ID=27157556

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1991/000253A AP249A (en) 1990-04-24 1991-04-23 Anti-viral compounds.

Country Status (37)

Country Link
US (2) US5360817A (cs)
EP (2) EP0786458B1 (cs)
JP (1) JP2944750B2 (cs)
KR (1) KR0169496B1 (cs)
CN (3) CN1143853C (cs)
AP (1) AP249A (cs)
AT (2) ATE161253T1 (cs)
AU (2) AU7533891A (cs)
BG (1) BG62092B1 (cs)
CA (2) CA2081356C (cs)
CY (1) CY2186B1 (cs)
CZ (1) CZ288492B6 (cs)
DE (3) DE19975068I2 (cs)
DK (1) DK0526543T3 (cs)
ES (2) ES2313730T3 (cs)
FI (2) FI105478B (cs)
GR (1) GR3026225T3 (cs)
HK (1) HK1003834A1 (cs)
HU (2) HU219355B (cs)
IE (2) IE980526A1 (cs)
IL (1) IL97936A (cs)
LU (1) LU90468I2 (cs)
MY (1) MY107843A (cs)
NL (1) NL990030I2 (cs)
NO (3) NO302751B1 (cs)
NZ (1) NZ237936A (cs)
OA (1) OA09679A (cs)
PL (3) PL167630B1 (cs)
PT (1) PT97460B (cs)
RU (1) RU2119487C1 (cs)
SG (1) SG43170A1 (cs)
SI (1) SI9110745B (cs)
SK (1) SK282950B6 (cs)
UA (1) UA41252C2 (cs)
WO (1) WO1991016320A1 (cs)
YU (1) YU48741B (cs)
ZA (1) ZA913086B (cs)

Families Citing this family (134)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2081068C (en) * 1991-10-23 2005-11-29 Laurence Mark Von Itzstein Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of .alpha.-d-neuraminic acid
GB9126725D0 (en) * 1991-12-17 1992-02-12 Glaxo Group Ltd Process
GB9220327D0 (en) * 1992-09-25 1992-11-11 Glaxo Group Ltd Process
GB9220241D0 (en) * 1992-09-25 1992-11-11 Glaxo Group Ltd Process
GB9312531D0 (en) * 1993-06-17 1993-08-04 Glaxo Group Ltd Process
US5958973A (en) * 1993-09-03 1999-09-28 Gilead Sciences, Inc. Polyhydroxy benzoic acid derivatives and their use as neuraminidase inhibitors
GB9325841D0 (en) * 1993-12-17 1994-02-23 Glaxo Group Ltd Chemical compounds
GB9400206D0 (en) * 1994-01-07 1994-03-02 Glaxo Group Ltd Chemical compound
AUPM354694A0 (en) * 1994-01-27 1994-02-17 Biota Scientific Management Pty Ltd Chemical compounds
US5985859A (en) * 1994-04-14 1999-11-16 The University Of Alabama Methods of inhibiting bacterial sialidase
US5453533A (en) * 1994-04-14 1995-09-26 The University Of Alabama At Birmingham Inhibitors of influenza virus neuraminidase and methods of making and using the same
AU687197B2 (en) * 1994-05-27 1998-02-19 Daikin Industries, Ltd. 7-fluoro-2, 3-didehydrosialic acid and intermediate for synthesis thereof
GB9410817D0 (en) * 1994-05-28 1994-07-20 Glaxo Group Ltd Medicaments
AUPM725794A0 (en) * 1994-08-03 1994-08-25 Biota Scientific Management Pty Ltd Chemical compounds
US5556963A (en) * 1994-08-05 1996-09-17 Oklahoma Medical Research Foundation Synthesis of 4-alkoxy-N-acetylneuraminic acid
GB9416365D0 (en) * 1994-08-12 1994-10-05 Glaxo Group Ltd Medicaments
US5512596A (en) * 1994-09-02 1996-04-30 Gilead Sciences, Inc. Aromatic compounds
US5475109A (en) * 1994-10-17 1995-12-12 Merck & Co., Inc. Dioxobutanoic acid derivatives as inhibitors of influenza endonuclease
CN102952033A (zh) * 1995-02-27 2013-03-06 吉里德科学公司 新颖化合物,其合成方法及治疗用途
CN101143859A (zh) * 1995-02-27 2008-03-19 吉里德科学公司 新颖化合物,其合成方法及治疗用途
SG45864A1 (en) * 1995-02-27 1999-04-27 Novel selective inhibitors of viral or bacterial neuraminidases
US5866601A (en) * 1995-02-27 1999-02-02 Gilead Sciences, Inc. Carbocyclic compounds
AU4259500A (en) * 1995-02-27 2000-08-31 Gilead Sciences, Inc. Novel compounds and methods for synthesis and therapy
US5602277A (en) * 1995-03-30 1997-02-11 Biocryst Pharmaceuticals, Inc. Substituted benzene derivatives useful as neuraminidase inhibitors
US5714509A (en) * 1995-05-03 1998-02-03 The University Of Alabama Inhibitors of bacterial sialidase and methods of making and using the same
CZ366697A3 (cs) * 1995-05-19 1998-04-15 Biota Scientific Management Pty. Ltd. Deriváty 6-karboxamidodihydropyranu
GB9516276D0 (en) * 1995-08-08 1995-10-11 Biota Scient Management Chemical compounds
JPH0967270A (ja) * 1995-08-31 1997-03-11 Res Dev Corp Of Japan 水晶体混濁の予防および治療法、並びにそのための薬 剤
US5763483A (en) * 1995-12-29 1998-06-09 Gilead Sciences, Inc. Carbocyclic compounds
DE69721242T2 (de) 1996-03-01 2004-01-29 Biota Scient Management Verfahren zum nachweis von influenza-virus und dazu verwendbare verbindungen
US6093816A (en) 1996-06-27 2000-07-25 Isis Pharmaceuticals, Inc. Cationic lipids
US6451766B1 (en) 1996-07-22 2002-09-17 Sankyo Company, Limited Neuraminic acid derivatives, their preparation and their medical use
US6340702B1 (en) 1996-07-22 2002-01-22 Sankyo Company, Limited Neuraminic acid derivatives, their preparation and their medical use
DK0823428T3 (da) * 1996-07-22 2002-02-18 Sankyo Co Neuraminsyrederivater, deres fremstilling og deres medicinske anvendelse
DE69721553T2 (de) * 1996-08-13 2004-07-22 Sankyo Co., Ltd. Verbindungen der neuraminsaeure
US6518438B2 (en) 1996-08-23 2003-02-11 Gilead Sciences, Inc. Preparation of cyclohexene carboxylate derivatives
US5859284A (en) 1996-08-23 1999-01-12 Gilead Sciences, Inc. Preparation of carbocyclic compounds
EP0882721A4 (en) * 1996-09-10 1999-12-22 Daikin Ind Ltd SIALIC ACIDS 2,7-DIDEOXY-7-FLUORO- 2, 3-DIDEHYDRO A QUADRUPLE SUBSTITUTION
US5719020A (en) * 1996-09-25 1998-02-17 Oklahoma Medical Research Foundation 4,7-dialkoxy N-acetylneuraminic acid derivatives and methods for detection of influenza type A and B viruses in clinical specimens
US5994377A (en) 1996-10-21 1999-11-30 Gilead Sciences, Inc. Piperidine compounds
AU743333B2 (en) * 1996-10-21 2002-01-24 Gilead Sciences, Inc. Piperidine compounds
TR199901081T2 (xx) * 1996-11-14 1999-08-23 Biota Scientific Management Pty.Ltd. Y�ntem ve bu y�ntemde kullan�lan yeni bile�imler.
US5886213A (en) * 1997-08-22 1999-03-23 Gilead Sciences, Inc. Preparation of carbocyclic compounds
JP3390965B2 (ja) 1997-09-12 2003-03-31 理化学研究所 糖結合スフィンゴシンを含有するポリマー化合物
US20040053999A1 (en) * 1997-09-17 2004-03-18 Bischofberger Norbert W. Novel compounds and methods for synthesis and therapy
CN1272105A (zh) * 1997-09-17 2000-11-01 吉里德科学公司 含六元环的化合物,其制备方法及其作为药物的用途
US20030129146A1 (en) * 1997-10-31 2003-07-10 Vincent Fischetti The use of bacterial phage associated lysing proteins for treating bacterial dental caries
TW477783B (en) * 1997-12-12 2002-03-01 Gilead Sciences Inc Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
US6518305B1 (en) 1998-04-23 2003-02-11 Abbott Laboratories Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases
WO1999054290A1 (en) * 1998-04-23 1999-10-28 Abbott Laboratories Inhibitors of neuraminidases
US6455571B1 (en) 1998-04-23 2002-09-24 Abbott Laboratories Inhibitors of neuraminidases
HUP0103481A3 (en) 1998-07-15 2003-01-28 Jomaa Hassan Phosphorous organic compounds and their use and pharmaceutical compositions containing them
US6303764B1 (en) 1998-09-24 2001-10-16 Zymetx, Inc. Synthesis of 4,7-dialkyl chromogenic glycosides of N-acetylneuraminic acids
US6664235B1 (en) 1999-08-20 2003-12-16 Riken Medicaments comprising sialic acid derivatives as active ingredients
US6420552B1 (en) 1999-09-10 2002-07-16 Zymetx, Inc. Syntheses of 4-alkyl chromogenic glycosides and 7-alkyl chromogenic glycosides of N-acetylneuraminic acids
AU2039301A (en) * 1999-10-19 2001-04-30 Abbott Laboratories Neuraminidase inhibitors
US6593314B1 (en) 1999-10-19 2003-07-15 Abbott Laboratories Neuraminidase inhibitors
US6627396B1 (en) 1999-10-28 2003-09-30 The Regents Of The University Of California Influenza sensor
SE9904289D0 (sv) * 1999-11-26 1999-11-26 Niklas Arnberg Method and camposition for the treatment of adenovairal ocular infections
CA3036031C (en) 2000-03-06 2021-04-13 Craig T. Jordan A compound that selectively binds to cd123 and use thereof to kill hematologic cancer progenitor cells
GB0015324D0 (en) * 2000-06-22 2000-08-16 Biota Scient Management Medicaments
AUPR001000A0 (en) 2000-09-08 2000-10-05 Biota Scientific Management Pty Ltd Novel chemical compounds and their use
WO2003025133A2 (en) * 2001-09-14 2003-03-27 Mimeon, Inc. Methods of making glycolmolecules with enhanced activities and uses thereof
JP2006241024A (ja) * 2005-03-01 2006-09-14 Takashi Suzuki 新規シアル酸誘導体
AR060623A1 (es) 2006-04-27 2008-07-02 Astrazeneca Ab Compuestos derivados de 2-azetidinona y un metodo de preparacion
CN100471848C (zh) * 2006-06-05 2009-03-25 中国医学科学院医药生物技术研究所 一组长链烷氧烷基取代唾液酸衍生物及其制备方法
US20080063722A1 (en) * 2006-09-08 2008-03-13 Advanced Inhalation Research, Inc. Composition of a Spray-Dried Powder for Pulmonary Delivery of a Long Acting Neuraminidase Inhibitor (LANI)
KR101494231B1 (ko) 2007-01-23 2015-02-17 쎄라피콘 에스.알.엘. 항바이러스 화합물
US20080194801A1 (en) * 2007-02-14 2008-08-14 Swanson Basil I Robust multidentate ligands for diagnosis and anti-viral drugs for influenza and related viruses
US7981930B2 (en) * 2007-03-13 2011-07-19 Adamas Pharmaceuticals, Inc. Compositions and kits for treating influenza
US7960139B2 (en) 2007-03-23 2011-06-14 Academia Sinica Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
EP2137655B1 (en) 2007-04-16 2012-07-11 Momenta Pharmaceuticals, Inc. Defined glycoprotein products and related methods
CA2697837C (en) 2007-08-31 2016-08-16 Academia Sinica Synthesis of oseltamivir containing phosphonate congeners with anti-influenza activity
WO2009129305A2 (en) 2008-04-15 2009-10-22 Tsrl, Inc. Prodrugs of neuraminidase inhibitors
DK2318832T3 (da) 2008-07-15 2014-01-20 Academia Sinica Glycan-arrays på PTFE-lignende aluminiumcoatede objektglas og relaterede fremgangsmåder
JP2012510456A (ja) 2008-11-28 2012-05-10 シプラ・リミテッド ザナミビルの製造方法及び該方法に使用するための中間体
TWI491416B (zh) 2008-12-24 2015-07-11 Daiichi Sankyo Co Ltd 吸入用乾燥粉末醫藥組成物
EP2228054A1 (en) * 2009-03-13 2010-09-15 ITALFARMACO S.p.A. Riluzole aqueous suspensions
CA2760106C (en) * 2009-05-04 2020-03-10 National Research Council Of Canada Inhibitors of sialidase or sialidase-like enzymes
EA201101564A1 (ru) * 2009-05-15 2012-07-30 Редкс Фарма Лимитед Редокс производные лекарственных средств
CA2767453C (en) * 2009-07-15 2018-10-09 The University Of British Columbia Neuraminidase inhibitor compounds, compositions and methods for the use thereof as anti-virals
WO2011006208A1 (en) * 2009-07-16 2011-01-20 Griffith University Anti -influenza agents
IT1396620B1 (it) 2009-11-25 2012-12-14 Therapicon Srl Analoghi chimerici
US10087236B2 (en) 2009-12-02 2018-10-02 Academia Sinica Methods for modifying human antibodies by glycan engineering
US11377485B2 (en) 2009-12-02 2022-07-05 Academia Sinica Methods for modifying human antibodies by glycan engineering
JP2011136964A (ja) * 2009-12-28 2011-07-14 Gifu Univ ノイラミン酸誘導体、シアリダーゼ活性阻害剤及び抗インフルエンザ薬
WO2011127322A1 (en) 2010-04-07 2011-10-13 Momenta Pharmaceuticals, Inc. High mannose glycans
US10338069B2 (en) 2010-04-12 2019-07-02 Academia Sinica Glycan arrays for high throughput screening of viruses
CN103068378B (zh) 2010-05-10 2016-07-06 中央研究院 具有抗流感活性的扎那米韦膦酸酯同类物及其制备方法
CN101921251B (zh) * 2010-09-21 2011-10-05 仙居县圃瑞药业有限公司 扎那米韦中间体的精制工艺方法
CN102464640A (zh) * 2010-10-29 2012-05-23 江苏正大天晴药业股份有限公司 扎那米韦的制备方法
AT510585B1 (de) 2010-11-18 2012-05-15 Apeptico Forschung & Entwicklung Gmbh Zusammensetzung umfassend ein peptid und ein hemmstoff der viralen neuraminidase
WO2012114350A1 (en) 2011-02-24 2012-08-30 Cadila Healthcare Limited Process for the preparation of zanamivir
WO2012125553A2 (en) 2011-03-12 2012-09-20 Momenta Pharmaceuticals, Inc. N-acetylhexosamine-containing n-glycans in glycoprotein products
WO2012142492A2 (en) * 2011-04-15 2012-10-18 University Of Georgia Research Foundation, Inc. Methods for inhibiting virus replication
KR101369584B1 (ko) 2011-04-19 2014-03-06 일양약품주식회사 페닐-이속사졸 유도체 및 그의 제조방법
WO2013093458A2 (en) 2011-12-21 2013-06-27 Redx Pharma Limited Antiviral drug derivatives
US9637465B2 (en) 2012-01-19 2017-05-02 The University Of British Columbia 3′ Equatorial-fluorine-substituted neuraminidase inhibitor compounds, compositions and methods for the use thereof as anti-virals
US10130714B2 (en) 2012-04-14 2018-11-20 Academia Sinica Enhanced anti-influenza agents conjugated with anti-inflammatory activity
WO2013181575A2 (en) 2012-06-01 2013-12-05 Momenta Pharmaceuticals, Inc. Methods related to denosumab
AU2013306098A1 (en) 2012-08-18 2015-02-12 Academia Sinica Cell-permeable probes for identification and imaging of sialidases
KR102186030B1 (ko) 2012-10-29 2020-12-03 시플라 리미티드 항 바이러스성 포스포네이트 유사체 및 이의 제조를 위한 방법
WO2014149067A1 (en) 2013-03-15 2014-09-25 Momenta Pharmaceuticals, Inc. Methods related to ctla4-fc fusion proteins
EP2996772B1 (en) 2013-05-13 2018-12-19 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
WO2014210397A1 (en) 2013-06-26 2014-12-31 Academia Sinica Rm2 antigens and use thereof
US9981030B2 (en) 2013-06-27 2018-05-29 Academia Sinica Glycan conjugates and use thereof
CN103396957B (zh) * 2013-07-11 2015-08-19 中国海洋大学 一种来源于鲤链霉菌的海洋微生物多糖及其制备方法
CN105682666B (zh) 2013-09-06 2021-06-01 中央研究院 使用醣脂激活人类iNKT细胞
CN111116533B (zh) * 2013-09-09 2022-11-22 中国科学院上海有机化学研究所 扎那米韦和拉那米韦的中间体及其合成方法
EP3058084A4 (en) 2013-10-16 2017-07-05 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins
JP6453050B2 (ja) * 2013-11-15 2019-01-16 国立大学法人富山大学 2−デオキシ−2,3−ジデヒドロシアル酸誘導体およびその製造法
US10150818B2 (en) 2014-01-16 2018-12-11 Academia Sinica Compositions and methods for treatment and detection of cancers
EP3094352B1 (en) 2014-01-16 2020-09-23 Academia Sinica Compositions and methods for treatment and detection of cancers
WO2015148915A1 (en) 2014-03-27 2015-10-01 Academia Sinica Reactive labelling compounds and uses thereof
AU2015260841A1 (en) 2014-05-12 2016-12-01 Glaxosmithkline Intellectual Property (No. 2) Limited Pharmaceutical compositions comprising danirixin for treating infectious diseases
KR20170010003A (ko) 2014-05-27 2017-01-25 아카데미아 시니카 박테로이드 기원의 푸코시다제 및 이의 사용 방법
KR20170003720A (ko) 2014-05-27 2017-01-09 아카데미아 시니카 항-cd20 글리코항체 및 이의 용도
US10118969B2 (en) 2014-05-27 2018-11-06 Academia Sinica Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
IL249188B2 (en) 2014-05-27 2024-03-01 Academia Sinica Anti-her2 glycoantibodies and uses thereof
CN106714829A (zh) 2014-05-28 2017-05-24 中央研究院 抗TNF‑α醣抗体及其用途
NL2013420B1 (en) * 2014-09-05 2016-09-27 Univ Griffith Antiviral agents and uses thereof.
CA2960712A1 (en) 2014-09-08 2016-03-17 Academia Sinica Human inkt cell activation using glycolipids
EP3210995B1 (en) 2014-10-24 2022-03-30 PeptiDream Inc. Hemagglutinin-binding peptide
US9975965B2 (en) 2015-01-16 2018-05-22 Academia Sinica Compositions and methods for treatment and detection of cancers
US10495645B2 (en) 2015-01-16 2019-12-03 Academia Sinica Cancer markers and methods of use thereof
CA2972072A1 (en) 2015-01-24 2016-07-28 Academia Sinica Novel glycan conjugates and methods of use thereof
WO2017156192A1 (en) 2016-03-08 2017-09-14 Academia Sinica Methods for modular synthesis of n-glycans and arrays thereof
TWI764917B (zh) 2016-08-22 2022-05-21 醣基生醫股份有限公司 抗體、結合片段及使用方法
CN106520864A (zh) * 2016-09-28 2017-03-22 南京农业大学 一种酶法合成唾液酸类似物的方法及其应用
CA3064774A1 (en) * 2017-05-25 2018-11-29 The Governors Of The University Of Alberta Methods of preventing or treating atherosclerosis with inhibitors of specific isoenzymes of human neuraminidase
WO2021209563A1 (en) 2020-04-16 2021-10-21 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus
WO2023119230A1 (en) 2021-12-22 2023-06-29 L'oreal Coagulation pathway and nicotinamide-adenine dinucleotide pathway modulating compositions and methods of their use
JP2024546179A (ja) 2021-12-23 2024-12-17 サブイントロ リミテッド 新規な抗ウイルス性のオレイン酸含有組成物
US20230310474A1 (en) * 2022-02-11 2023-10-05 Cleveland State University Coronavirus treatment composition and method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE627295A (cs) 1962-01-18

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HELVETICA CHIMICA ACTA, Vol. 69, 1986, pp. 1191-1204 *
LIEBIGS ANN. CHEM.: 1989, pp. 159-165 *

Also Published As

Publication number Publication date
ATE161253T1 (de) 1998-01-15
PL166918B1 (pl) 1995-07-31
NO974670D0 (no) 1997-10-09
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AU654815B2 (en) 1994-11-24
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UA41252C2 (uk) 2001-09-17
CA2291994C (en) 2003-10-14
HK1010191A1 (en) 1999-06-17
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IL97936A (en) 1995-12-08
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ATE406358T1 (de) 2008-09-15
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KR0169496B1 (ko) 1999-01-15
AU7759091A (en) 1991-11-11
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CA2291994A1 (en) 1991-10-25
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CA2081356A1 (en) 1991-10-25
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ZA913086B (en) 1992-12-30
NO1999021I1 (no) 1999-09-17
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HK1003834A1 (en) 1998-11-06

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