ZA966711B - Chemical synthesis. - Google Patents

Chemical synthesis.

Info

Publication number
ZA966711B
ZA966711B ZA9606711A ZA966711A ZA966711B ZA 966711 B ZA966711 B ZA 966711B ZA 9606711 A ZA9606711 A ZA 9606711A ZA 966711 A ZA966711 A ZA 966711A ZA 966711 B ZA966711 B ZA 966711B
Authority
ZA
South Africa
Prior art keywords
chemical synthesis
synthesis
chemical
Prior art date
Application number
ZA9606711A
Other languages
English (en)
Inventor
Rajnikant Patel
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of ZA966711B publication Critical patent/ZA966711B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
ZA9606711A 1995-08-07 1996-08-07 Chemical synthesis. ZA966711B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9516145.1A GB9516145D0 (en) 1995-08-07 1995-08-07 Improved chemical synthesis

Publications (1)

Publication Number Publication Date
ZA966711B true ZA966711B (en) 1997-02-18

Family

ID=10778867

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9606711A ZA966711B (en) 1995-08-07 1996-08-07 Chemical synthesis.

Country Status (34)

Country Link
US (2) US6084103A (de)
EP (2) EP1227095B1 (de)
JP (6) JP3729503B2 (de)
KR (1) KR100670704B1 (de)
CN (3) CN1244579C (de)
AR (2) AR006515A1 (de)
AT (2) ATE227723T1 (de)
AU (1) AU718413B2 (de)
BR (1) BR9609830A (de)
CA (2) CA2227039C (de)
CZ (2) CZ301603B6 (de)
DE (2) DE69624825T2 (de)
DK (2) DK1227095T3 (de)
ES (2) ES2185790T3 (de)
GB (1) GB9516145D0 (de)
HK (2) HK1047094B (de)
HU (1) HU229966B1 (de)
IL (4) IL156733A (de)
IN (2) IN185148B (de)
MX (1) MX9801044A (de)
MY (1) MY117571A (de)
NO (2) NO311690B1 (de)
NZ (1) NZ315040A (de)
PL (1) PL188805B1 (de)
PT (2) PT843672E (de)
RO (2) RO121816B1 (de)
RU (1) RU2167875C2 (de)
SI (2) SI0843672T1 (de)
SK (1) SK285052B6 (de)
TR (1) TR199800182T1 (de)
TW (1) TW358811B (de)
UA (1) UA53625C2 (de)
WO (1) WO1997006162A1 (de)
ZA (1) ZA966711B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001004088A1 (fr) * 1999-07-09 2001-01-18 Chugai Seiyaku Kabushiki Kaisha Procede de preparation de derives d'amiline
ES2204302B2 (es) 2002-08-07 2005-03-01 Laboratorios Vita, S.A. Procedimiento para la obtencion de un compuesto farmaceuticamente activo.
WO2005075467A2 (en) * 2004-02-06 2005-08-18 Ciba Specialty Chemicals Holding Inc. Crystalline forms of zolmitriptan
EP1812428A2 (de) * 2004-11-19 2007-08-01 Teva Pharmaceutical Industries Ltd Zolmitriptan-kristallformen
CN101248184B (zh) 2005-08-25 2013-01-16 宇部兴产株式会社 光学活性（S或R）-α-氨基酸及光学活性（S或R）-α-氨基酸酯的制造方法
EP1981860B1 (de) 2006-01-19 2011-05-25 Matrix Laboratories Ltd Umwandlung eines aromatischen diazoniumsalzes in ein arylhydrazin
WO2008007390A2 (en) * 2006-07-10 2008-01-17 Natco Pharma Limited An improved process for purification of zolmitriptan
WO2008018090A2 (en) * 2006-08-09 2008-02-14 Matrix Laboratories Ltd An improved process for the preparation of zolmitriptan
CZ2007158A3 (cs) * 2007-02-26 2008-10-22 Zentiva, A. S. Zpusob prípravy zolmitriptanu
CZ301538B6 (cs) * 2007-02-26 2010-04-07 Zentiva, A. S. Zpusob prípravy zolmitriptanu
CN101883766A (zh) * 2007-10-03 2010-11-10 基因里克斯(英国)有限公司 制备佐米曲普坦、其盐和溶剂化物的方法
CN101230047B (zh) * 2008-02-04 2010-08-04 江苏中威药业有限公司 一种4-取代手性噁唑烷酮类化合物的制备方法
US8906949B2 (en) 2010-05-21 2014-12-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Orally disintegrating tablets of zolmitriptan and process for preparing the same
CN101948443B (zh) * 2010-08-17 2012-08-22 河南师范大学 一种简单、高效合成4-取代噁唑烷酮衍生物的方法
EP2691396B1 (de) 2011-03-30 2016-08-10 Brown University Enopeptine, verwendungen davon und syntheseverfahren dafür
US9006453B2 (en) 2011-09-02 2015-04-14 Emcure Pharmaceuticals Limited Process for preparation of zolmitriptan
CN102964270B (zh) * 2012-11-21 2015-01-07 合肥星宇化学有限责任公司 一种亚硫酸钠还原重氮盐合成肼的方法
CN103275075B (zh) * 2013-06-24 2015-01-07 成都天台山制药有限公司 佐米曲普坦及其制备方法
WO2016037072A2 (en) * 2014-09-04 2016-03-10 Brown University Enopeptin analogas and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8724912D0 (en) * 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
YU48855B (sh) * 1990-06-07 2002-06-19 The Wellcome Foundation Limited Heterociklična jedinjenja i njihovi derivati koji su modifikatori dejstva 5-hidroksi-triptamina i postupak njihovog dobijanja
GB9401436D0 (en) * 1994-01-26 1994-03-23 Wellcome Found Therapeutic heterocyclic compounds
GB9423682D0 (en) * 1994-11-23 1995-01-11 Merck Sharp & Dohme Therapeutic agents
CA2207201A1 (en) * 1994-12-06 1996-06-13 Caroline Henry Azetidine, pyrrolidine and piperidine derivatives as 5ht1 receptor agonists

Also Published As

Publication number Publication date
PL188805B1 (pl) 2005-04-29
PT1227095E (pt) 2006-08-31
EP0843672A1 (de) 1998-05-27
IN189756B (de) 2003-04-19
IN185148B (de) 2000-11-25
HU229966B1 (hu) 2015-03-30
ATE227723T1 (de) 2002-11-15
CN1201460A (zh) 1998-12-09
AU718413B2 (en) 2000-04-13
SK285052B6 (sk) 2006-05-04
ES2185790T3 (es) 2003-05-01
BR9609830A (pt) 1999-03-09
AR046236A2 (es) 2005-11-30
CN1317480A (zh) 2001-10-17
IL123171A (en) 2003-10-31
ATE325121T1 (de) 2006-06-15
AR006515A1 (es) 1999-09-08
HK1047094B (zh) 2006-10-13
TW358811B (en) 1999-05-21
TR199800182T1 (xx) 1998-05-21
ES2261545T3 (es) 2006-11-16
JP3739678B2 (ja) 2006-01-25
JP3729503B2 (ja) 2005-12-21
US6084103A (en) 2000-07-04
IL123171A0 (en) 1998-09-24
CZ301603B6 (cs) 2010-04-28
EP1227095A2 (de) 2002-07-31
RO121816B1 (ro) 2008-05-30
AU6663496A (en) 1997-03-05
HUP9900188A2 (hu) 1999-05-28
CN1244579C (zh) 2006-03-08
WO1997006162A1 (en) 1997-02-20
DE69636107T2 (de) 2007-05-03
CN1142904C (zh) 2004-03-24
NO20005187D0 (no) 2000-10-16
CA2572508C (en) 2010-03-30
MX9801044A (es) 1998-05-31
NO980522D0 (no) 1998-02-06
DE69636107D1 (de) 2006-06-08
CZ293050B6 (cs) 2004-01-14
RU2167875C2 (ru) 2001-05-27
RO119618B1 (ro) 2005-01-28
CA2227039C (en) 2007-12-04
JP2002097178A (ja) 2002-04-02
CA2227039A1 (en) 1997-02-20
NZ315040A (en) 2000-01-28
KR19990036165A (ko) 1999-05-25
HK1047094A1 (en) 2003-02-07
DE69624825T2 (de) 2003-09-04
SI0843672T1 (en) 2003-04-30
SK15498A3 (en) 1998-06-03
IL156733A0 (en) 2004-02-08
US6160123A (en) 2000-12-12
MY117571A (en) 2004-07-31
UA53625C2 (uk) 2003-02-17
EP1227095B1 (de) 2006-05-03
JP2006077025A (ja) 2006-03-23
EP1227095A3 (de) 2003-11-19
PL324881A1 (en) 1998-06-22
CN1403455A (zh) 2003-03-19
JP2002308858A (ja) 2002-10-23
JPH11513023A (ja) 1999-11-09
JP4634286B2 (ja) 2011-02-16
HK1009129A1 (en) 1999-05-28
IL148030A0 (en) 2002-09-12
CZ35298A3 (cs) 1998-06-17
CN1092657C (zh) 2002-10-16
CA2572508A1 (en) 1997-02-20
KR100670704B1 (ko) 2007-07-11
IL148030A (en) 2010-05-17
DK0843672T3 (da) 2003-02-17
HUP9900188A3 (en) 1999-11-29
GB9516145D0 (en) 1995-10-04
NO20005187L (no) 1998-02-06
JP2002037786A (ja) 2002-02-06
DK1227095T3 (da) 2006-07-31
DE69624825D1 (de) 2002-12-19
NO311691B1 (no) 2002-01-07
NO980522L (no) 1998-02-06
SI1227095T1 (sl) 2006-08-31
JP2006225406A (ja) 2006-08-31
EP0843672B1 (de) 2002-11-13
IL156733A (en) 2007-07-04
NO311690B1 (no) 2002-01-07
PT843672E (pt) 2003-03-31

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