ZA873438B - Trans-6-(2-(3-or 4-carboxamido-substituted pyrrol-1-yl)alkyl)-4-hydroxypyran-2-one inhibitors of cholesterol synthesis - Google Patents

Trans-6-(2-(3-or 4-carboxamido-substituted pyrrol-1-yl)alkyl)-4-hydroxypyran-2-one inhibitors of cholesterol synthesis

Info

Publication number
ZA873438B
ZA873438B ZA873438A ZA873438A ZA873438B ZA 873438 B ZA873438 B ZA 873438B ZA 873438 A ZA873438 A ZA 873438A ZA 873438 A ZA873438 A ZA 873438A ZA 873438 B ZA873438 B ZA 873438B
Authority
ZA
South Africa
Prior art keywords
hydroxypyran
carboxamido
alkyl
trans
inhibitors
Prior art date
Application number
ZA873438A
Other languages
English (en)
Inventor
Bruce D Roth
D Roth Bruce
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25352470&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA873438(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA873438B publication Critical patent/ZA873438B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
ZA873438A 1986-05-30 1987-05-13 Trans-6-(2-(3-or 4-carboxamido-substituted pyrrol-1-yl)alkyl)-4-hydroxypyran-2-one inhibitors of cholesterol synthesis ZA873438B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/868,867 US4681893A (en) 1986-05-30 1986-05-30 Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis

Publications (1)

Publication Number Publication Date
ZA873438B true ZA873438B (en) 1988-12-28

Family

ID=25352470

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA873438A ZA873438B (en) 1986-05-30 1987-05-13 Trans-6-(2-(3-or 4-carboxamido-substituted pyrrol-1-yl)alkyl)-4-hydroxypyran-2-one inhibitors of cholesterol synthesis

Country Status (23)

Country Link
US (1) US4681893A (ko)
EP (1) EP0247633B1 (ko)
JP (1) JPH0757751B2 (ko)
KR (1) KR940001006B1 (ko)
AT (1) ATE60602T1 (ko)
AU (1) AU601981B2 (ko)
CA (1) CA1268768A (ko)
DE (2) DE19775019I2 (ko)
DK (1) DK171588B1 (ko)
ES (1) ES2019899T4 (ko)
FI (1) FI88617C (ko)
GR (1) GR3001415T3 (ko)
HK (1) HK119493A (ko)
IE (1) IE60014B1 (ko)
LU (1) LU90147I2 (ko)
MX (1) MX9203095A (ko)
NL (1) NL970034I2 (ko)
NO (2) NO168645C (ko)
NZ (1) NZ220409A (ko)
PH (2) PH24661A (ko)
PT (1) PT84975B (ko)
SA (1) SA99200199A (ko)
ZA (1) ZA873438B (ko)

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