|
US4294846A
(en)
*
|
1979-09-21 |
1981-10-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and products of preparation
|
|
US4282155A
(en)
*
|
1980-02-04 |
1981-08-04 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4351844A
(en)
*
|
1980-02-04 |
1982-09-28 |
Merck & Co., Inc. |
Hypocholesterolemic hydrogenation products and process of preparation
|
|
PT72394B
(en)
*
|
1980-02-04 |
1982-09-06 |
Merck & Co Inc |
Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics
|
|
AU548996B2
(en)
|
1980-02-04 |
1986-01-09 |
Merck & Co., Inc. |
Tetrahydro-2h-pyran-2-one derivatives
|
|
US4444784A
(en)
*
|
1980-08-05 |
1984-04-24 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4293496A
(en)
*
|
1980-02-04 |
1981-10-06 |
Merck & Co., Inc. |
6(R)-[2-(8-Hydroxy-2,6-dimethylpolyhydronaphthyl-1)-ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones
|
|
JPH0692381B2
(ja)
*
|
1980-03-31 |
1994-11-16 |
三共株式会社 |
Mb−530a誘導体
|
|
JPS56150037A
(en)
*
|
1980-04-22 |
1981-11-20 |
Sankyo Co Ltd |
Hydronaphthalene compound
|
|
US4420491A
(en)
*
|
1980-05-28 |
1983-12-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
US4450171A
(en)
*
|
1980-08-05 |
1984-05-22 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4432996A
(en)
*
|
1980-11-17 |
1984-02-21 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products and process of preparation
|
|
US4343814A
(en)
*
|
1980-11-17 |
1982-08-10 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products
|
|
JPS57144279A
(en)
*
|
1981-03-02 |
1982-09-06 |
Sankyo Co Ltd |
Dihydro ml-236b and dihydro mb-530b and derivative thereof
|
|
US4387242A
(en)
*
|
1981-08-21 |
1983-06-07 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products and process of preparation
|
|
US4376863A
(en)
*
|
1981-08-21 |
1983-03-15 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products
|
|
US4503072A
(en)
*
|
1982-12-22 |
1985-03-05 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4582915A
(en)
*
|
1983-10-11 |
1986-04-15 |
Merck & Co., Inc. |
Process for C-methylation of 2-methylbutyrates
|
|
US4584389A
(en)
*
|
1983-10-11 |
1986-04-22 |
Merck & Co., Inc. |
Processes for preparing 6(R)-[2-[8(S)(2,2-dimethylbutyryloxy)-2(S),6(S)-dimethyl-1,2,3,4,4a(S),5,6,7,8,8a(S)-decahydronaphthyl-1(S)]ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one
|
|
US5208258A
(en)
*
|
1985-10-11 |
1993-05-04 |
The Regents Of The University Of California |
Antihypercholesterolemic compounds and synthesis thereof
|
|
US4950775A
(en)
*
|
1985-10-11 |
1990-08-21 |
University Of California |
Antihypercholesterolemic compounds and synthesis thereof
|
|
US4738982A
(en)
*
|
1986-04-28 |
1988-04-19 |
Merck & Co., Inc. |
HMG-CoA reductase inhibitors
|
|
USRE36481E
(en)
*
|
1986-06-23 |
2000-01-04 |
Merck & Co., Inc. |
HMG-CoA reductase inhibitors
|
|
US4940727A
(en)
*
|
1986-06-23 |
1990-07-10 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
|
US5116870A
(en)
*
|
1986-06-23 |
1992-05-26 |
Merck & Co., Inc. |
HMG-CoA reductase inhibitors
|
|
JPS6334525U
(enExample)
*
|
1986-08-26 |
1988-03-05 |
|
|
|
US4678806A
(en)
*
|
1986-09-02 |
1987-07-07 |
Merck & Co., Inc. |
Prodrugs of antihypercholesterolemic compounds
|
|
US4845237A
(en)
*
|
1987-04-15 |
1989-07-04 |
Merck & Co., Inc. |
Acylation process for the synthesis of HMG-CoA reductase inhibitors
|
|
US4719229A
(en)
*
|
1987-05-13 |
1988-01-12 |
Merck & Co., Inc. |
Antihypercholesterolemic agents
|
|
US4782084A
(en)
*
|
1987-06-29 |
1988-11-01 |
Merck & Co., Inc. |
HMG-COA reductase inhibitors
|
|
DE3739882A1
(de)
*
|
1987-11-25 |
1989-06-08 |
Bayer Ag |
Substituierte hydroxylamine
|
|
US5595734A
(en)
*
|
1988-04-06 |
1997-01-21 |
Alfacell Corporation |
Compositions comprising ONCONASE (tm) and lovastatin
|
|
US5075327A
(en)
*
|
1988-08-10 |
1991-12-24 |
Hoffmann-La Roche Inc. |
Antipsoriatic agents
|
|
JPH0251582A
(ja)
*
|
1988-08-12 |
1990-02-21 |
Kyokado Eng Co Ltd |
地盤注入用薬液
|
|
NL8902441A
(nl)
*
|
1988-10-03 |
1990-05-01 |
Glaxo Group Ltd |
Chemische verbinding.
|
|
US5021451A
(en)
*
|
1988-11-14 |
1991-06-04 |
Hoffman-La Roche Inc. |
Method for inhibiting hyperproliferative diseases
|
|
US5200549A
(en)
*
|
1988-11-14 |
1993-04-06 |
Hoffman-La Roche Inc. |
Antipsoriatic agents
|
|
US5073568A
(en)
*
|
1988-11-14 |
1991-12-17 |
Hoffmann-La Roche Inc. |
Antipsoriatic agents
|
|
US5376383A
(en)
*
|
1988-11-21 |
1994-12-27 |
Merck & Co., Inc. |
Method for enhancing the lowering of plasma-cholesterol levels
|
|
US5260305A
(en)
*
|
1988-12-12 |
1993-11-09 |
E. R. Squibb & Sons, Inc. |
Combination of pravastatin and nicotinic acid or related acid and method for lowering serum cholesterol using such combination
|
|
AU618158B2
(en)
*
|
1989-01-07 |
1991-12-12 |
Bayer Aktiengesellschaft |
New substituted pyrido(2,3-d)pyrimidines
|
|
US5166364A
(en)
*
|
1989-02-27 |
1992-11-24 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives useful as antihypercholesterolemic agents and method for preparing same
|
|
JPH02229630A
(ja)
*
|
1989-03-01 |
1990-09-12 |
Kyodo Kumiai F I T |
金型
|
|
JPH02148727U
(enExample)
*
|
1989-04-27 |
1990-12-18 |
|
|
|
CA2016467A1
(en)
|
1989-06-05 |
1990-12-05 |
Martin Eisman |
Method for treating peripheral atherosclerotic disease employing an hmg coa reductase inhibitor and/or a squalene synthetase inhibitor
|
|
US5001148A
(en)
*
|
1989-06-07 |
1991-03-19 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives
|
|
US5145959A
(en)
*
|
1989-07-18 |
1992-09-08 |
Bayer Aktiengesellschaft |
Substituted pyrido (2,3-d) pyrimidines as intermediates
|
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
|
US4970221A
(en)
*
|
1989-07-28 |
1990-11-13 |
E. R. Squibb & Sons, Inc. |
3,5-dihydroxypentanoic acid derivatives useful as antihypercholesterolemic agents and method for preparing same
|
|
DE3929507A1
(de)
*
|
1989-09-06 |
1991-03-07 |
Bayer Ag |
Substituierte amino-pyridine
|
|
US5316765A
(en)
*
|
1989-09-07 |
1994-05-31 |
Karl Folkers Foundation For Biomedical And Clinical Research |
Use of coenzyme Q10 in combination with HMG-CoA reductase inhibitor therapies
|
|
US5173487A
(en)
*
|
1989-11-13 |
1992-12-22 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives
|
|
US5264455A
(en)
*
|
1990-07-06 |
1993-11-23 |
E. R. Squibb & Sons, Inc. |
Sulfur-substituted mevinic acid derivatives
|
|
US5223415A
(en)
*
|
1990-10-15 |
1993-06-29 |
Merck & Co., Inc. |
Biosynthetic production of 7-[1',2',6',7',8',8a'(R)-hexahydro-2'(S),6'(R)-dimethyl-8'(S)-hydroxy-1'(S)-naphthyl]-3(R),5(R)-dihydroxyheptanoic acid (triol acid)
|
|
US5177080A
(en)
|
1990-12-14 |
1993-01-05 |
Bayer Aktiengesellschaft |
Substituted pyridyl-dihydroxy-heptenoic acid and its salts
|
|
US5288928A
(en)
*
|
1990-12-21 |
1994-02-22 |
Ciba-Geigy Corporation |
Asymmetrical hydrogenation
|
|
US5202029A
(en)
*
|
1991-03-13 |
1993-04-13 |
Caron Kabushiki Kaisha |
Process for purification of hmg-coa reductase inhibitors
|
|
US5151365A
(en)
*
|
1991-03-18 |
1992-09-29 |
Merck & Co., Inc. |
Culture of Asperigillus versicolor and mutants thereof
|
|
US5250435A
(en)
*
|
1991-06-04 |
1993-10-05 |
Merck & Co., Inc. |
Mutant strains of Aspergillus terreus for producing 7-[1,2,6,7,8,8a(R)-hexa-hydro-2(S),6(R)-dimethyl-8(S)-hydroxy-1(S)-naphthyl]-3(R),5(R)-dihydroxyheptanoic acid (triol acid),I)
|
|
US5364948A
(en)
*
|
1991-08-02 |
1994-11-15 |
Merck & Co., Inc. |
Biologically active compounds isolated from aerobic fermentation of Trichoderma viride
|
|
EP0526936A3
(en)
*
|
1991-08-02 |
1993-05-05 |
Merck & Co. Inc. |
Cholesterol-lowering agents
|
|
US5286746A
(en)
*
|
1991-12-20 |
1994-02-15 |
E. R. Squibb & Sons, Inc. |
Sulfur-substituted mevinic acid derivatives
|
|
HU208997B
(en)
*
|
1992-06-17 |
1994-02-28 |
Gyogyszerkutato Intezet |
Microbiological method for producing mevinoline
|
|
JP3233476B2
(ja)
*
|
1992-10-22 |
2001-11-26 |
社団法人北里研究所 |
Fo−1289物質およびその製造法
|
|
DE4243279A1
(de)
*
|
1992-12-21 |
1994-06-23 |
Bayer Ag |
Substituierte Triole
|
|
DE4244029A1
(de)
*
|
1992-12-24 |
1994-06-30 |
Bayer Ag |
Neue substituierte Pyridine
|
|
US6190894B1
(en)
|
1993-03-19 |
2001-02-20 |
The Regents Of The University Of California |
Method and compositions for disrupting the epithelial barrier function
|
|
SI9300303A
(en)
*
|
1993-06-08 |
1994-12-31 |
Krka Tovarna Zdravil |
Process for isolation of hypolipemic effective substance
|
|
US5409820A
(en)
*
|
1993-08-06 |
1995-04-25 |
Apotex, Inc. |
Process for the production of lovastatin using Coniothyrium fuckelii
|
|
US5849541A
(en)
*
|
1993-11-02 |
1998-12-15 |
Merck & Co., Inc. |
DNA encoding triol polyketide synthase
|
|
WO1995013063A1
(en)
*
|
1993-11-09 |
1995-05-18 |
Merck & Co., Inc. |
HMG-CoA REDUCTASE INHIBITORS IN THE NORMALIZATION OF VASCULAR ENDOTHELIAL DYSFUNCTION
|
|
US5730992A
(en)
*
|
1994-09-13 |
1998-03-24 |
Ramot University Authority For Applied Research And Industrial Development, Ltd. |
Compositions for the treatment of skin disorders
|
|
US6642268B2
(en)
|
1994-09-13 |
2003-11-04 |
G.D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
|
|
US6268392B1
(en)
|
1994-09-13 |
2001-07-31 |
G. D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
|
|
US6262277B1
(en)
|
1994-09-13 |
2001-07-17 |
G.D. Searle And Company |
Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
|
|
IL110943A
(en)
*
|
1994-09-13 |
1997-02-18 |
Univ Ramot |
Compositions comprising an inhibitor of cholesterol synthesis for the treatment of skin disorders
|
|
IL115420A0
(en)
|
1994-09-26 |
1995-12-31 |
Zeneca Ltd |
Aminoheterocyclic derivatives
|
|
US20110196039A9
(en)
*
|
1994-10-05 |
2011-08-11 |
Kaesemeyer Wayne H |
Controlled release arginine formulations
|
|
US5674488A
(en)
*
|
1994-10-07 |
1997-10-07 |
Reich; John J. |
Method for prevention and treatment of hyperchlolesterolemia by in vivo hydrogenation of cholesterol
|
|
US5616595A
(en)
*
|
1995-06-07 |
1997-04-01 |
Abbott Laboratories |
Process for recovering water insoluble compounds from a fermentation broth
|
|
GB9602166D0
(en)
*
|
1996-02-02 |
1996-04-03 |
Zeneca Ltd |
Aminoheterocyclic derivatives
|
|
JP2000504336A
(ja)
|
1996-02-02 |
2000-04-11 |
ゼネカ・リミテッド |
薬学製剤として有用なヘテロ環式化合物
|
|
US5763653A
(en)
*
|
1997-03-13 |
1998-06-09 |
Ranbaxy Laboratories, Ltd. |
Key intermediates in the manufacture of simvastatin
|
|
DE19627420A1
(de)
*
|
1996-07-08 |
1998-01-15 |
Bayer Ag |
6-(Hydroxymethyl-ethyl)pyridine
|
|
IL128428A0
(en)
*
|
1996-08-14 |
2000-01-31 |
Zeneca Ltd |
Substituted pyrimidine derivatives and their pharmaceutical use
|
|
US7238348B2
(en)
*
|
1996-09-30 |
2007-07-03 |
Beijing Peking University Wbl Corporation Ltd. |
Method of treatment of osteoporosis with compositions of red rice fermentation products
|
|
US6046022A
(en)
*
|
1996-09-30 |
2000-04-04 |
Peking University |
Methods and compositions employing red rice fermentation products
|
|
UA56197C2
(uk)
*
|
1996-11-08 |
2003-05-15 |
Зенека Лімітед |
Гетероциклічні похідні
|
|
US5763646A
(en)
*
|
1997-03-13 |
1998-06-09 |
Ranbaxy Laboratories, Ltd. |
Process for manufacturing simvastatin from lovastatin or mevinolinic acid
|
|
WO1998035959A1
(en)
|
1997-02-13 |
1998-08-20 |
Zeneca Limited |
Heterocyclic compounds useful as oxido-squalene cyclase inhibitors
|
|
WO1998035956A1
(en)
|
1997-02-13 |
1998-08-20 |
Zeneca Limited |
Heterocyclic compounds useful as oxido-squalene cyclase inhibitors
|
|
DE69834630T2
(de)
*
|
1997-02-20 |
2007-04-19 |
Dsm Ip Assets B.V. |
Fermentative herstellung von wertstoffen in industriellem umfang durch verwendung von chemisch definierten media
|
|
EP0877089A1
(en)
|
1997-05-07 |
1998-11-11 |
Gist-Brocades B.V. |
HMG-CoA reductase inhibitor preparation process
|
|
GB9715895D0
(en)
|
1997-07-29 |
1997-10-01 |
Zeneca Ltd |
Heterocyclic compounds
|
|
US20010006644A1
(en)
|
1997-07-31 |
2001-07-05 |
David J. Bova |
Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
|
|
KR100234976B1
(ko)
*
|
1997-08-01 |
1999-12-15 |
김충환 |
세룰레닌 및 엘-메치오닌 유사체에 동시 내성을 갖는 아스퍼질 러스속 미생물 및 그를 이용한 메비놀린산의 제조방법
|
|
GT199800127A
(es)
*
|
1997-08-29 |
2000-02-01 |
|
Combinaciones terapeuticas.
|
|
US6177121B1
(en)
|
1997-09-29 |
2001-01-23 |
Purdue Research Foundation |
Composition and method for producing low cholesterol eggs
|
|
US6147109A
(en)
*
|
1997-10-14 |
2000-11-14 |
The General Hospital Corporation |
Upregulation of Type III endothelial cell Nitric Oxide Synthase by HMG-CoA reductase inhibitors
|
|
US6083497A
(en)
|
1997-11-05 |
2000-07-04 |
Geltex Pharmaceuticals, Inc. |
Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
|
|
US20080275104A1
(en)
*
|
1997-11-25 |
2008-11-06 |
Musc Foundation For Research Development |
Methods of treating juvenile type 1 diabetes mellitus
|
|
US8679534B2
(en)
*
|
1997-12-12 |
2014-03-25 |
Andrx Labs, Llc |
HMG-CoA reductase inhibitor extended release formulation
|
|
US20040029962A1
(en)
*
|
1997-12-12 |
2004-02-12 |
Chih-Ming Chen |
HMG-COA reductase inhibitor extended release formulation
|
|
US6180597B1
(en)
|
1998-03-19 |
2001-01-30 |
Brigham And Women's Hospital, Inc. |
Upregulation of Type III endothelial cell nitric oxide synthase by rho GTPase function inhibitors
|
|
US6432931B1
(en)
|
1998-06-24 |
2002-08-13 |
Merck & Co., Inc. |
Compositions and methods for inhibiting bone resorption
|
|
US20030078211A1
(en)
*
|
1998-06-24 |
2003-04-24 |
Merck & Co., Inc. |
Compositions and methods for inhibiting bone resorption
|
|
US6423751B1
(en)
|
1998-07-14 |
2002-07-23 |
The Brigham And Women's Hospital, Inc. |
Upregulation of type III endothelial cell nitric oxide synthase by agents that disrupt actin cytoskeletal organization
|
|
US5985907A
(en)
*
|
1998-08-12 |
1999-11-16 |
Health Research, Inc. |
Method for inhibiting growth of methanogens
|
|
IL141786A0
(en)
|
1998-09-17 |
2002-03-10 |
Bristol Myers Squibb Co |
A pharmaceutical composition for treating diabetes containing an ap2 inhibitor
|
|
US7141602B2
(en)
*
|
1998-09-18 |
2006-11-28 |
Lek Pharmaceuticals D.D. |
Process for obtaining HMG-CoA reductase inhibitors of high purity
|
|
SI20072A
(sl)
*
|
1998-09-18 |
2000-04-30 |
LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. |
Postopek za pridobivanje inhibitorjev HMG-CoA reduktaze
|
|
US20080213378A1
(en)
*
|
1998-10-01 |
2008-09-04 |
Elan Pharma International, Ltd. |
Nanoparticulate statin formulations and novel statin combinations
|
|
PL201578B1
(pl)
|
1998-11-20 |
2009-04-30 |
Skyepharma Canada Inc |
Stała terapeutyczna postać dawkowania nierozpuszczalnego lub słabo rozpuszczalnego w wodzie związku
|
|
US6391583B1
(en)
|
1998-12-18 |
2002-05-21 |
Wisconsin Alumni Research Foundation |
Method of producing antihypercholesterolemic agents
|
|
ATE242008T1
(de)
|
1998-12-23 |
2003-06-15 |
Searle Llc |
Kombnationen von cholesteryl ester transfer protein inhibitoren und gallensäure sequestriermitteln für kardiovaskuläre indikationen
|
|
ATE240120T1
(de)
|
1998-12-23 |
2003-05-15 |
Searle Llc |
Kombinationen von ileumgallensäuretransports inhibitoren und fibronsäure derivaten für kardiovaskuläre indikationen
|
|
WO2000038724A1
(en)
*
|
1998-12-23 |
2000-07-06 |
G.D. Searle Llc |
Combinations of cholesteryl ester transfer protein inhibitors and fibric acid derivatives for cardiovascular indications
|
|
EA005815B1
(ru)
*
|
1998-12-23 |
2005-06-30 |
Джи.Ди.Сирл Ллс |
Комбинация ингибиторов транспорта желчных кислот в подвздошной кишке и ингибиторов белка, переносящего эфиры холестерина, для сердечно-сосудистых показаний
|
|
AU779264B2
(en)
*
|
1998-12-23 |
2005-01-13 |
G.D. Searle Llc |
Combinations for cardiovascular indications
|
|
WO2000038728A1
(en)
|
1998-12-23 |
2000-07-06 |
G.D. Searle Llc |
Combinations of ileal bile acid transport inhibitors and bile acid sequestring agents for cardiovascular indications
|
|
WO2000038722A1
(en)
|
1998-12-23 |
2000-07-06 |
G.D. Searle & Co. |
COMBINATIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND HMG CoA REDUCTASE INHIBITORS FOR CARDIOVASCULAR INDICATIONS
|
|
ATE242007T1
(de)
*
|
1998-12-23 |
2003-06-15 |
Searle Llc |
Kombinationen von cholesteryl ester transfer protein inhibitoren und nicotinsäure derivaten für kardiovaskuläre indikationen
|
|
US6323021B1
(en)
|
1999-01-15 |
2001-11-27 |
Industrial Technology Research Institute |
Mutant strain of penicillium citrinum and use thereof for preparation of compactin
|
|
GB9902989D0
(en)
|
1999-02-11 |
1999-03-31 |
Zeneca Ltd |
Heterocyclic derivatives
|
|
US6569461B1
(en)
*
|
1999-03-08 |
2003-05-27 |
Merck & Co., Inc. |
Dihydroxy open-acid and salts of HMG-CoA reductase inhibitors
|
|
SE9903028D0
(sv)
*
|
1999-08-27 |
1999-08-27 |
Astra Ab |
New use
|
|
IL148127A0
(en)
*
|
1999-08-30 |
2002-09-12 |
Aventis Pharma Gmbh |
Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events
|
|
EP1225901A2
(en)
*
|
1999-09-21 |
2002-07-31 |
Emory University |
Uses and compositions for treating platelet-related disorders using anagrelide
|
|
US6372462B2
(en)
|
1999-10-15 |
2002-04-16 |
Medmyco Ltd. |
Process for producing, methods and compositions of cholesterol lowering agents from higher basidiomycetes mushrooms
|
|
AU8030900A
(en)
|
1999-10-27 |
2001-05-08 |
Merck & Co., Inc. |
Lactonization process
|
|
KR100342789B1
(ko)
|
1999-10-29 |
2002-07-04 |
김용규 |
니스타틴에 내성을 갖는 아스퍼질러스속 미생물 및 그를 이용한 트리올 헵타노익산의 제조방법
|
|
DE60138535D1
(de)
|
2000-02-04 |
2009-06-10 |
Children S Hospital Res Founda |
Verwendung von lysosomal acid lipase zur behandlung von atherosklerose und ähnlichen krankheiten
|
|
EP1286984A2
(en)
|
2000-03-10 |
2003-03-05 |
Pharmacia Corporation |
Method for the preparation of tetrahydrobenzothiepines
|
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
|
WO2001068096A2
(en)
*
|
2000-03-10 |
2001-09-20 |
Pharmacia Corporation |
Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
|
|
DE10030375A1
(de)
*
|
2000-06-21 |
2002-01-03 |
Bayer Ag |
Verwendung von MTP-Inhibitoren zur Senkung von ppTRL
|
|
IN192861B
(enExample)
|
2000-06-30 |
2004-05-22 |
Ranbaxy Lab Ltd |
|
|
EP1314425A4
(en)
*
|
2000-08-30 |
2004-06-02 |
Sankyo Co |
MEDICINAL COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF HEART FAILURE
|
|
JO2654B1
(en)
|
2000-09-04 |
2012-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Multiple aryl caroxa amides are useful as lipid - lowering agents
|
|
US8586094B2
(en)
|
2000-09-20 |
2013-11-19 |
Jagotec Ag |
Coated tablets
|
|
CN1468098A
(zh)
*
|
2000-10-05 |
2004-01-14 |
�ݰ¸Ƕ�ҩ������˾ |
基本上无普伐他汀内酯和表普伐他汀的普伐他汀钠和包含普伐他汀钠的组合物
|
|
US20030162829A1
(en)
*
|
2000-10-06 |
2003-08-28 |
George Kindness |
Combination of treatment of cancer utilizing a COX-2 inhibitor and a 3-hydroxy-3-methylglutaryl-coenzyme-a (HMG-CoA) reductase inhibitor
|
|
US6534540B2
(en)
|
2000-10-06 |
2003-03-18 |
George Kindness |
Combination and method of treatment of cancer utilizing a COX-2 inhibitor and a 3-hydroxy-3-methylglutaryl-coenzyme-a (HMG-CoA) reductase inhibitor
|
|
PL361097A1
(en)
*
|
2000-10-12 |
2004-09-20 |
Nissan Chemical Industries, Ltd. |
Preventives and remedies for complications of diabetes
|
|
US6777552B2
(en)
*
|
2001-08-16 |
2004-08-17 |
Teva Pharmaceutical Industries, Ltd. |
Processes for preparing calcium salt forms of statins
|
|
JO2409B1
(en)
*
|
2000-11-21 |
2007-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Second-phenyl carboxy amides are useful as lipid-lowering agents
|
|
JO2390B1
(en)
*
|
2001-04-06 |
2007-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Diphenylcarboxamides act as lipid-lowering agents
|
|
WO2002083066A2
(en)
|
2001-04-11 |
2002-10-24 |
Bristol-Myers Squibb Company |
Amino acid complexes of c-aryl glucosides for treatment of diabetes and method
|
|
CA2444028A1
(en)
*
|
2001-04-18 |
2002-10-31 |
Genzyme Corporation |
Methods of treating syndrome x with aliphatic polyamines
|
|
WO2002096416A1
(en)
*
|
2001-05-31 |
2002-12-05 |
Cellegy Pharmaceuticals, Inc. |
Store operated calcium influx inhibitors and methods of use
|
|
RU2192856C1
(ru)
*
|
2001-07-05 |
2002-11-20 |
Закрытое акционерное общество "ВЕРОФАРМ" |
Гипохолестеринемическое средство
|
|
US20040092565A1
(en)
*
|
2001-07-25 |
2004-05-13 |
George Kindness |
Composition and method of sustaining chemotherapeutic effect while reducing dose of chemotherapeutic agent using cox-2 inhibitor and statin
|
|
US20040077625A1
(en)
*
|
2001-07-25 |
2004-04-22 |
Tremont Samuel J. |
Novel 1,4-benzothiazepine and 1,5-benzothiazepine compounds as inhibitors of apical sodium codependent bile acid transport abd taurocholate uptake
|
|
AU2002348469B2
(en)
*
|
2001-10-18 |
2008-03-13 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
|
US7238671B2
(en)
*
|
2001-10-18 |
2007-07-03 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
|
BR0213501A
(pt)
*
|
2001-11-02 |
2004-08-24 |
Searle Llc |
Compostos de benzotiepina mono- e di-fluorada como inibidores de transporte de ácido biliar co-dependente de sódio apical (asbt) e captação de taurocolato
|
|
US6806381B2
(en)
*
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
|
IL161741A0
(en)
*
|
2001-11-09 |
2005-11-20 |
Atherogenics Inc |
Methods of reversing and preventingcardiovascular pathologies
|
|
AU2002348276A1
(en)
*
|
2001-11-16 |
2003-06-10 |
Bristol-Myers Squibb Company |
Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
|
|
US6831102B2
(en)
*
|
2001-12-07 |
2004-12-14 |
Bristol-Myers Squibb Company |
Phenyl naphthol ligands for thyroid hormone receptor
|
|
CA2469435A1
(en)
|
2001-12-21 |
2003-07-24 |
X-Ceptor Therapeutics, Inc. |
Modulators of lxr
|
|
US7482366B2
(en)
|
2001-12-21 |
2009-01-27 |
X-Ceptor Therapeutics, Inc. |
Modulators of LXR
|
|
US6696473B2
(en)
*
|
2001-12-21 |
2004-02-24 |
X-Ceptor Therapeutics, Inc. |
Heterocyclic modulators of nuclear receptors
|
|
WO2003061604A2
(en)
|
2002-01-17 |
2003-07-31 |
Pharmacia Corporation |
Novel alkyl/aryl hydroxy or keto thiepines.
|
|
EP1490090A4
(en)
|
2002-02-22 |
2006-09-20 |
New River Pharmaceuticals Inc |
SYSTEMS FOR DELIVERING ACTIVE AGENTS AND METHODS FOR PROTECTING AND DELIVERING ACTIVE AGENTS
|
|
KR100379075B1
(en)
*
|
2002-03-07 |
2003-04-08 |
Jinis Biopharmaceuticals Co |
Method for producing low cholesterol animal food product and food product therefrom
|
|
WO2003086395A1
(en)
|
2002-04-12 |
2003-10-23 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
CA2480325A1
(en)
*
|
2002-04-16 |
2003-10-30 |
Merck & Co., Inc. |
Solid forms of salts with tyrosine kinase activity
|
|
AU2003225305A1
(en)
|
2002-05-08 |
2003-11-11 |
Bristol-Myers Squibb Company |
Pyridine-based thyroid receptor ligands
|
|
PT2336359E
(pt)
|
2002-05-09 |
2016-06-03 |
The Brigham And Women`S Hospital Inc |
1l1rl-1 como um marcador de doença cardiovascular
|
|
EP1504525A2
(de)
*
|
2002-05-14 |
2005-02-09 |
Siemens Aktiengesellschaft |
Verfahren zum erzeugen eines sendesignals
|
|
US7057046B2
(en)
*
|
2002-05-20 |
2006-06-06 |
Bristol-Myers Squibb Company |
Lactam glycogen phosphorylase inhibitors and method of use
|
|
AU2003241477A1
(en)
*
|
2002-06-10 |
2003-12-22 |
Elan Pharma International, Ltd. |
Nanoparticulate polycosanol formulations and novel polycosanol combinations
|
|
US20050182106A1
(en)
*
|
2002-07-11 |
2005-08-18 |
Sankyo Company, Limited |
Medicinal composition for mitigating blood lipid or lowering blood homocysteine
|
|
CA2493645A1
(en)
*
|
2002-07-23 |
2004-01-29 |
Nutrinova Nutrition Specialties & Food Ingredients Gmbh |
Cholesterol-reducing agent made of dietary fibre and cholesterol-reducing substances
|
|
US20050182036A1
(en)
*
|
2002-08-02 |
2005-08-18 |
Sankyo Company, Limited |
Medicinal composition containing an HMG-CoA reductase inhibitor
|
|
US20050187204A1
(en)
*
|
2002-08-08 |
2005-08-25 |
Sankyo Company, Limited |
Medicinal composition for lowering blood lipid level
|
|
UA79300C2
(en)
*
|
2002-08-12 |
2007-06-11 |
Janssen Pharmaceutica Nv |
N-aryl piperidine substituted biphenylcarboxamides as inhibitors of apolipoprotein b secretion
|
|
US20060019269A1
(en)
*
|
2002-10-17 |
2006-01-26 |
Decode Genetics, Inc. |
Susceptibility gene for myocardial infarction, stroke, and PAOD, methods of treatment
|
|
US20080293750A1
(en)
*
|
2002-10-17 |
2008-11-27 |
Anna Helgadottir |
Susceptibility Gene for Myocardial Infarction, Stroke, Paod and Methods of Treatment
|
|
AU2003282983A1
(en)
*
|
2002-10-23 |
2004-05-13 |
Bristol-Myers Squibb Company |
Glycinenitrile-based inhibitors of dipeptidyl peptidase iv and methods
|
|
US20080145424A1
(en)
*
|
2002-10-24 |
2008-06-19 |
Enos Phramaceuticals, Inc. |
Sustained release L-arginine formulations and methods of manufacture and use
|
|
NZ539672A
(en)
*
|
2002-10-24 |
2006-09-29 |
Enos Pharmaceuticals Inc |
Sustained release L-arginine-formulations and methods of manufacture and use
|
|
US7098235B2
(en)
*
|
2002-11-14 |
2006-08-29 |
Bristol-Myers Squibb Co. |
Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds
|
|
US20040110241A1
(en)
*
|
2002-12-06 |
2004-06-10 |
Segal Mark S. |
Materials and methods for monitoring vascular endothelial function
|
|
US20040198800A1
(en)
*
|
2002-12-19 |
2004-10-07 |
Geoffrey Allan |
Lipoxygenase inhibitors as hypolipidemic and anti-hypertensive agents
|
|
JP2006513186A
(ja)
|
2002-12-20 |
2006-04-20 |
ファイザー・プロダクツ・インク |
Cetp阻害剤およびhmg−coaレダクターゼ阻害剤を含む剤形
|
|
US20040132771A1
(en)
*
|
2002-12-20 |
2004-07-08 |
Pfizer Inc |
Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
|
|
CA2510320C
(en)
*
|
2002-12-20 |
2012-10-09 |
St. James Associates Llc/Faber Research Series |
Coated particles for sustained-release pharmaceutical administration
|
|
DE10261061A1
(de)
*
|
2002-12-24 |
2004-07-15 |
Nutrinova Nutrition Specialties & Food Ingredients Gmbh |
Diätetisches Lebensmittel zur positiven Beeinflussung der kardiovaskulären Gesundheit
|
|
DE10261067A1
(de)
*
|
2002-12-24 |
2004-08-05 |
Nutrinova Nutrition Specialties & Food Ingredients Gmbh |
Cholesterinsenkendes Mittel, enthaltend eine n-3-Fettsäure
|
|
TW200504021A
(en)
*
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
|
JP2006516620A
(ja)
*
|
2003-01-24 |
2006-07-06 |
ブリストル−マイヤーズ スクイブ カンパニー |
甲状腺受容体におけるシクロアルキル含有アニリドリガンド
|
|
US7557143B2
(en)
*
|
2003-04-18 |
2009-07-07 |
Bristol-Myers Squibb Company |
Thyroid receptor ligands
|
|
ES2421520T3
(es)
*
|
2003-04-28 |
2013-09-03 |
Daiichi Sankyo Co Ltd |
Potenciador de la producción de adiponectina
|
|
EP1618893A4
(en)
*
|
2003-04-28 |
2009-08-12 |
Sankyo Co |
MEANS FOR INCREASING SUGAR CAPACITY
|
|
US7459474B2
(en)
*
|
2003-06-11 |
2008-12-02 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
|
US7368468B2
(en)
*
|
2003-06-18 |
2008-05-06 |
Teva Pharmaceutical Industries Ltd. |
Fluvastatin sodium crystal forms XIV, LXXIII, LXXIX, LXXX and LXXXVII, processes for preparing them, compositions containing them and methods of using them
|
|
CA2529859A1
(en)
|
2003-06-18 |
2004-12-29 |
Teva Pharmaceutical Industries Ltd |
Fluvastatin sodium crystal forms xiv, lxxiii ,lxxix, lxxx and lxxxvii, processes for preparing them, compositions containing them and methods of using them
|
|
EP1643969A2
(en)
*
|
2003-07-11 |
2006-04-12 |
Pro-Pharmaceuticals, Inc. |
Compositions and methods for hydrophobic drug delivery
|
|
US6995183B2
(en)
*
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
JP4553899B2
(ja)
|
2003-08-21 |
2010-09-29 |
メルク フロスト カナダ リミテツド |
カテプシンシステインプロテアーゼ阻害剤
|
|
EP1510208A1
(en)
*
|
2003-08-22 |
2005-03-02 |
Fournier Laboratories Ireland Limited |
Pharmaceutical composition comprising a combination of metformin and statin
|
|
US7396927B2
(en)
*
|
2003-08-28 |
2008-07-08 |
Teva Pharmaceutical Industries Ltd. |
Process for preparation of rosuvastatin calcium
|
|
US20050053664A1
(en)
*
|
2003-09-08 |
2005-03-10 |
Eliezer Zomer |
Co-administration of a polysaccharide with a chemotherapeutic agent for the treatment of cancer
|
|
US20050171207A1
(en)
*
|
2003-09-26 |
2005-08-04 |
Myriad Genetics, Incorporated |
Method and composition for combination treatment of neurodegenerative disorders
|
|
JP2007521324A
(ja)
*
|
2003-09-29 |
2007-08-02 |
エノス ファーマシューティカルズ, インク. |
徐放性l−アルギニン調合物並びにその製造法及び使用法
|
|
US8227434B1
(en)
|
2003-11-04 |
2012-07-24 |
H. Lee Moffitt Cancer Center & Research Institute, Inc. |
Materials and methods for treating oncological disorders
|
|
JP4839221B2
(ja)
*
|
2003-11-07 |
2011-12-21 |
ジェイ ジェイ ファーマ,インコーポレイテッド |
Hdlを高める併用療法用複合物
|
|
US7317109B2
(en)
*
|
2003-11-12 |
2008-01-08 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
US7576121B2
(en)
*
|
2003-11-12 |
2009-08-18 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
DK1689757T3
(en)
*
|
2003-11-12 |
2014-12-08 |
Sino Med Internat Alliance Inc |
HETEROCYCLIC DRY ACID COMPOUNDS
|
|
US7767828B2
(en)
*
|
2003-11-12 |
2010-08-03 |
Phenomix Corporation |
Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
WO2005051298A2
(en)
|
2003-11-19 |
2005-06-09 |
Metabasis Therapeutics, Inc. |
Novel phosphorus-containing thyromimetics
|
|
WO2005051921A1
(en)
*
|
2003-11-24 |
2005-06-09 |
Teva Pharmaceutical Industries Ltd. |
Crystalline ammonium salts of rosuvastatin
|
|
US8415364B2
(en)
*
|
2003-11-26 |
2013-04-09 |
Duke University |
Method of preventing or treating glaucoma
|
|
US7244844B2
(en)
*
|
2003-12-02 |
2007-07-17 |
Teva Pharmaceutical Industries Ltd. |
Reference standard for characterization of rosuvastatin
|
|
US20070099891A1
(en)
*
|
2003-12-17 |
2007-05-03 |
Kouichi Kino |
Medicinal compositions and combinations
|
|
US20070179166A1
(en)
*
|
2003-12-24 |
2007-08-02 |
Valerie Niddam-Hildesheim |
Process for preparation of statins with high syn to anti ratio
|
|
US7851624B2
(en)
*
|
2003-12-24 |
2010-12-14 |
Teva Pharamaceutical Industries Ltd. |
Triol form of rosuvastatin and synthesis of rosuvastatin
|
|
WO2005063728A2
(en)
*
|
2003-12-24 |
2005-07-14 |
Teva Pharmaceutical Industries Ltd. |
Process for preparation of statins with high syn to anti ratio
|
|
US20070161700A1
(en)
*
|
2004-12-28 |
2007-07-12 |
Kowa Company, Ltd. |
Inhibitor for the formation of y-secretase complex
|
|
US8158362B2
(en)
*
|
2005-03-30 |
2012-04-17 |
Decode Genetics Ehf. |
Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype
|
|
US20100216863A1
(en)
*
|
2004-01-30 |
2010-08-26 |
Decode Genetics Ehf. |
Susceptibility Gene for Myocardial Infarction, Stroke, and PAOD; Methods of Treatment
|
|
EP1563837A1
(en)
*
|
2004-02-03 |
2005-08-17 |
Ferrer Internacional, S.A. |
Hypocholesterolemic compositions comprising a statin and an antiflatulent agent
|
|
EP1718146A2
(en)
*
|
2004-02-13 |
2006-11-08 |
Pro-Pharmaceuticals, Inc. |
Compositions and methods used to treat acne and candida
|
|
US8309574B2
(en)
*
|
2004-02-25 |
2012-11-13 |
Kowa Company, Ltd. |
Nuclear transfer promoter for Rac protein and method of screening the same
|
|
JP4728226B2
(ja)
|
2004-02-25 |
2011-07-20 |
興和株式会社 |
Cdc42タンパク質の核内移行促進剤及びそのスクリーニング方法
|
|
SI1725234T1
(sl)
|
2004-03-05 |
2013-04-30 |
The Trustees Of The University Of Pennsylvania |
Postopki zdravljenja nepravilnosti ali bolezni povezanih s hiperlipidemijo in hiperholesterolemijo z minimiziranjem stranskih uäśinkov
|
|
US7262318B2
(en)
*
|
2004-03-10 |
2007-08-28 |
Pfizer, Inc. |
Substituted heteroaryl- and phenylsulfamoyl compounds
|
|
US20060211752A1
(en)
|
2004-03-16 |
2006-09-21 |
Kohn Leonard D |
Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
|
|
JP2007529554A
(ja)
*
|
2004-03-19 |
2007-10-25 |
プロ−ファーマシューティカルズ,インク. |
多価リガンド結合糖質ポリマーを用いた組成物、および該組成物による転移腫瘍の標的療法
|
|
ATE414071T1
(de)
*
|
2004-03-30 |
2008-11-15 |
Lupin Ltd |
Verbessertes verfahren zur herstellung von 4- hydroxypyran-2-onderivaten
|
|
KR100598326B1
(ko)
|
2004-04-10 |
2006-07-10 |
한미약품 주식회사 |
HMG-CoA 환원효소 억제제의 경구투여용 서방형 제제및 이의 제조방법
|
|
WO2005115380A2
(en)
*
|
2004-05-27 |
2005-12-08 |
Dexcel Pharma Technologies Ltd |
Localized controlled absorption of statins in the gastrointestinal tract for achieving high blood levels of statins
|
|
US7803838B2
(en)
*
|
2004-06-04 |
2010-09-28 |
Forest Laboratories Holdings Limited |
Compositions comprising nebivolol
|
|
US20050288340A1
(en)
*
|
2004-06-29 |
2005-12-29 |
Pfizer Inc |
Substituted heteroaryl- and phenylsulfamoyl compounds
|
|
TW200611704A
(en)
*
|
2004-07-02 |
2006-04-16 |
Bristol Myers Squibb Co |
Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions
|
|
US7145040B2
(en)
*
|
2004-07-02 |
2006-12-05 |
Bristol-Myers Squibb Co. |
Process for the preparation of amino acids useful in the preparation of peptide receptor modulators
|
|
US7534763B2
(en)
|
2004-07-02 |
2009-05-19 |
Bristol-Myers Squibb Company |
Sustained release GLP-1 receptor modulators
|
|
US7786163B2
(en)
*
|
2004-07-12 |
2010-08-31 |
Forest Laboratories Holdings Limited (BM) |
Constrained cyano compounds
|
|
JP2007508379A
(ja)
*
|
2004-07-13 |
2007-04-05 |
テバ ファーマシューティカル インダストリーズ リミティド |
Tempo媒介型酸化段階を包含するロスバスタチンの調製方法
|
|
US7572805B2
(en)
|
2004-07-14 |
2009-08-11 |
Bristol-Myers Squibb Company |
Pyrrolo(oxo)isoquinolines as 5HT ligands
|
|
US20110217412A1
(en)
*
|
2004-07-30 |
2011-09-08 |
Jinis Biopharmaceuticals Co. |
Cholesterol lowering supplement and low cholesterol egg produced by using the same
|
|
KR100637762B1
(ko)
*
|
2004-07-30 |
2006-10-23 |
주식회사 지니스 |
저콜레스테롤 란을 생산하기 위한 가금류용 사료첨가제 및 이를 이용한 저콜레스테롤 란의 생산방법
|
|
US20080286251A1
(en)
*
|
2004-08-02 |
2008-11-20 |
Propharmaceuticals, Inc. |
Compositions and Methods for the Enhancement of Chemotherapy with Microbial Cytotoxins
|
|
WO2006017692A2
(en)
*
|
2004-08-06 |
2006-02-16 |
Transform Pharmaceuticals, Inc. |
Novel fenofibrate formulations and related methods of treatment
|
|
MX2007001553A
(es)
*
|
2004-08-06 |
2008-03-07 |
Transform Pharmaceuticals Inc |
Nuevas composiciones farmaceuticas de estatina y metodos de tratamiento relacionados.
|
|
US20090042979A1
(en)
*
|
2004-08-06 |
2009-02-12 |
Transform Pharmaceuticals Inc. |
Novel Statin Pharmaceutical Compositions and Related Methods of Treatment
|
|
US20060058261A1
(en)
*
|
2004-09-15 |
2006-03-16 |
Andre Aube |
Chitin derivatives for hyperlipidemia
|
|
AR051446A1
(es)
*
|
2004-09-23 |
2007-01-17 |
Bristol Myers Squibb Co |
Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2)
|
|
ES2439229T3
(es)
|
2004-10-06 |
2014-01-22 |
The Brigham And Women's Hospital, Inc. |
Relevancia de niveles logrados de marcadores de inflamación sistémica tras el tratamiento
|
|
US7517991B2
(en)
*
|
2004-10-12 |
2009-04-14 |
Bristol-Myers Squibb Company |
N-sulfonylpiperidine cannabinoid receptor 1 antagonists
|
|
WO2006045008A2
(en)
*
|
2004-10-19 |
2006-04-27 |
Cargill, Incorporated |
Meat having increased level of hdl
|
|
CA2585623C
(en)
*
|
2004-10-27 |
2012-06-05 |
Daiichi Sankyo Company Limited |
Ortho-substituted benzene derivatives
|
|
US20090196889A1
(en)
*
|
2004-11-22 |
2009-08-06 |
Dexcel Pharma Technologies Ltd. |
Controlled absorption of statins in the intestine
|
|
AU2005314230B2
(en)
|
2004-12-09 |
2011-05-19 |
Merck Sharp & Dohme Corp. |
Estrogen receptor modulators
|
|
MX2007006279A
(es)
*
|
2004-12-15 |
2007-06-14 |
Solvay Pharm Gmbh |
Composiciones farmaceuticas que comprenden inhibidores de nep, inhibidores del sistema de produccion de endotelina endogena, e inhibidores de hmg coa-reductasa.
|
|
US7635699B2
(en)
*
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7589088B2
(en)
*
|
2004-12-29 |
2009-09-15 |
Bristol-Myers Squibb Company |
Pyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7368458B2
(en)
*
|
2005-01-12 |
2008-05-06 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
WO2006076569A2
(en)
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
WO2006076598A2
(en)
*
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
WO2006078697A1
(en)
*
|
2005-01-18 |
2006-07-27 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
ATE421518T1
(de)
*
|
2005-02-10 |
2009-02-15 |
Bristol Myers Squibb Co |
Dihydrochinazolinone als 5ht-modulatoren
|
|
US20070167625A1
(en)
*
|
2005-02-22 |
2007-07-19 |
Anna Balanov |
Preparation of rosuvastatin
|
|
US20070037979A1
(en)
*
|
2005-02-22 |
2007-02-15 |
Valerie Niddam-Hildesheim |
Preparation of rosuvastatin
|
|
CA2680693A1
(en)
*
|
2005-02-22 |
2006-08-31 |
Teva Pharmaceutical Industries Ltd. |
Preparation of rosuvastatin
|
|
US20070293535A1
(en)
*
|
2005-02-24 |
2007-12-20 |
Kowa Company, Ltd. |
Nuclear Transfer Promoter for Ddc42 Protein and Method of Screening the Dame
|
|
WO2007046842A2
(en)
|
2005-03-02 |
2007-04-26 |
Merck & Co., Inc. |
Composition for inhibition of cathepsin k
|
|
CA2603105A1
(en)
*
|
2005-03-28 |
2006-10-05 |
Dexcel Pharma Technologies Ltd. |
Controlled absorption of statins in the intestine
|
|
EP2527337A1
(en)
|
2005-04-14 |
2012-11-28 |
Bristol-Myers Squibb Company |
Inhibitors of 11-beta hydroxysteroid dehydrogenase type I
|
|
ATE550019T1
(de)
|
2005-05-17 |
2012-04-15 |
Merck Sharp & Dohme |
Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs
|
|
US7521557B2
(en)
|
2005-05-20 |
2009-04-21 |
Bristol-Myers Squibb Company |
Pyrrolopyridine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
WO2006125304A1
(en)
*
|
2005-05-25 |
2006-11-30 |
Liponex, Inc. |
Pharmaceutical compositions for treating or preventing coronary artery disease
|
|
US7825139B2
(en)
*
|
2005-05-25 |
2010-11-02 |
Forest Laboratories Holdings Limited (BM) |
Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
CN101282991A
(zh)
*
|
2005-05-26 |
2008-10-08 |
布里斯托尔-迈尔斯斯奎布公司 |
N-端修饰的胰高血糖素样肽-1受体调节剂
|
|
EP1890691A2
(en)
|
2005-05-31 |
2008-02-27 |
Mylan Laboratories, Inc |
Compositions comrising nebivolol
|
|
US7452892B2
(en)
*
|
2005-06-17 |
2008-11-18 |
Bristol-Myers Squibb Company |
Triazolopyrimidine cannabinoid receptor 1 antagonists
|
|
US7629342B2
(en)
*
|
2005-06-17 |
2009-12-08 |
Bristol-Myers Squibb Company |
Azabicyclic heterocycles as cannabinoid receptor modulators
|
|
TW200726765A
(en)
*
|
2005-06-17 |
2007-07-16 |
Bristol Myers Squibb Co |
Triazolopyridine cannabinoid receptor 1 antagonists
|
|
US7632837B2
(en)
*
|
2005-06-17 |
2009-12-15 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid-1 receptor modulators
|
|
US7317012B2
(en)
*
|
2005-06-17 |
2008-01-08 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoind-1 receptor modulators
|
|
US20060287342A1
(en)
*
|
2005-06-17 |
2006-12-21 |
Mikkilineni Amarendra B |
Triazolopyrimidine heterocycles as cannabinoid receptor modulators
|
|
US8569352B2
(en)
|
2005-06-27 |
2013-10-29 |
Exelixis Patent Company Llc |
Imidazole based LXR modulators
|
|
US20070015832A1
(en)
*
|
2005-07-14 |
2007-01-18 |
Myriad Genetics, Incorporated |
Methods of treating overactive bladder and urinary incontinence
|
|
KR20080034171A
(ko)
*
|
2005-07-28 |
2008-04-18 |
브리스톨-마이어스 스큅 컴퍼니 |
세로토닌 수용체 효능제 및 길항제로서의 치환된테트라히드로-1h-피리도[4,3,b]인돌
|
|
US7772277B2
(en)
*
|
2005-08-04 |
2010-08-10 |
Transform Pharmaceuticals, Inc. |
Formulations comprising fenofibrate and a statin, and related methods of treatment
|
|
MX2007004427A
(es)
*
|
2005-08-16 |
2007-06-14 |
Teva Pharma |
Intermedio de rosuvastatina cristalina.
|
|
US7795436B2
(en)
*
|
2005-08-24 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
|
|
TWI387592B
(zh)
|
2005-08-30 |
2013-03-01 |
Novartis Ag |
經取代之苯并咪唑及其作為與腫瘤形成相關激酶之抑制劑之方法
|
|
WO2007030302A2
(en)
*
|
2005-09-01 |
2007-03-15 |
Prescient Medical, Inc. |
Drugs coated on a device to treat vulnerable plaque
|
|
WO2007035395A2
(en)
*
|
2005-09-16 |
2007-03-29 |
Virginia Commonwealth University Intellectual Property Foundation |
Therapeutic compositions comprising chorionic gonadotropins and hmg coa reductase inhibitors
|
|
US8119358B2
(en)
|
2005-10-11 |
2012-02-21 |
Tethys Bioscience, Inc. |
Diabetes-related biomarkers and methods of use thereof
|
|
DE102005049293A1
(de)
*
|
2005-10-15 |
2007-04-26 |
Bayer Healthcare Ag |
Kombinationspräparate von Salzen oder o-Acetylsalicylsäure
|
|
US20070088089A1
(en)
*
|
2005-10-18 |
2007-04-19 |
Wisler Gerald L |
Methods for treating disorders associated with hyperlipidemia in a mammal
|
|
US7741317B2
(en)
|
2005-10-21 |
2010-06-22 |
Bristol-Myers Squibb Company |
LXR modulators
|
|
AR056155A1
(es)
|
2005-10-26 |
2007-09-19 |
Bristol Myers Squibb Co |
Antagonistas del receptor 1 de la hormona de concentracion de melanina no basica
|
|
US7488725B2
(en)
|
2005-10-31 |
2009-02-10 |
Bristol-Myers Squibb Co. |
Pyrrolidinyl beta-amino amide-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7888376B2
(en)
|
2005-11-23 |
2011-02-15 |
Bristol-Myers Squibb Company |
Heterocyclic CETP inhibitors
|
|
US7592461B2
(en)
|
2005-12-21 |
2009-09-22 |
Bristol-Myers Squibb Company |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
|
US20090018118A1
(en)
*
|
2005-12-29 |
2009-01-15 |
Uros Urleb |
Heterocyclic compounds
|
|
US20070238669A1
(en)
*
|
2006-01-11 |
2007-10-11 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes related conditions
|
|
US7553836B2
(en)
*
|
2006-02-06 |
2009-06-30 |
Bristol-Myers Squibb Company |
Melanin concentrating hormone receptor-1 antagonists
|
|
GB0603041D0
(en)
|
2006-02-15 |
2006-03-29 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
US20090069275A1
(en)
*
|
2006-02-17 |
2009-03-12 |
Rocca Jose G |
Low flush niacin formulation
|
|
CA2569776A1
(en)
*
|
2006-02-17 |
2007-08-17 |
Kos Life Sciences, Inc. |
Low flush niacin formulation
|
|
US20070238770A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Bristol-Myers Squibb Company |
Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations
|
|
JP5328640B2
(ja)
|
2006-04-19 |
2013-10-30 |
ノバルティス アーゲー |
6−o−置換ベンゾオキサゾールおよびベンゾチアゾール化合物ならびにcsf−1rシグナル伝達を阻害する方法
|
|
US20070269503A1
(en)
*
|
2006-05-16 |
2007-11-22 |
James Walter Burgess |
Combinations of HMG CoA reductase inhibitors and negatively charged phospholipids and uses thereof
|
|
US20100022457A1
(en)
*
|
2006-05-26 |
2010-01-28 |
Bristol-Myers Squibb Company |
Sustained release glp-1 receptor modulators
|
|
CA2659082A1
(en)
|
2006-06-07 |
2007-12-21 |
Tethys Bioscience, Inc. |
Markers associated with arteriovascular events and methods of use thereof
|
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
|
JPWO2008001499A1
(ja)
|
2006-06-29 |
2009-11-26 |
興和株式会社 |
関節リウマチの予防及び/又は治療薬
|
|
US20080044326A1
(en)
*
|
2006-07-04 |
2008-02-21 |
Esencia Co., Ltd. |
Sterilizer for baby products
|
|
US7795291B2
(en)
|
2006-07-07 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as anti-atherosclerotic, anti-dyslipidemic, anti-diabetic and anti-obesity agents and method
|
|
US7727978B2
(en)
|
2006-08-24 |
2010-06-01 |
Bristol-Myers Squibb Company |
Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
|
ES2532595T3
(es)
|
2006-08-30 |
2015-03-30 |
Kyushu University, National University Corporation |
Composición farmacéutica que contiene una nanopartícula de estatina encapsulada
|
|
EP2083831B1
(en)
|
2006-09-22 |
2013-12-25 |
Merck Sharp & Dohme Corp. |
Method of treatment using fatty acid synthesis inhibitors
|
|
US20080118572A1
(en)
*
|
2006-10-10 |
2008-05-22 |
Harold Richard Hellstrom |
Methods and compositions for reducing the risk of adverse cardiovascular events associated with the administration of artificial blood
|
|
EP2079448A2
(en)
*
|
2006-10-10 |
2009-07-22 |
Dexcel Pharma Technologies Ltd. |
Improved release of statins in the intestine
|
|
WO2008057862A2
(en)
|
2006-11-01 |
2008-05-15 |
Bristol-Myers Squibb Company |
MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ϰB ACTIVITY AND USE THEREOF
|
|
US20110218176A1
(en)
|
2006-11-01 |
2011-09-08 |
Barbara Brooke Jennings-Spring |
Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
|
|
EP2120927A1
(en)
*
|
2006-12-21 |
2009-11-25 |
Aegerion Pharmaceuticals, Inc. |
Methods for treating obesity with a combination comprising a mtp inhibitor and a cholesterol absorption inhibitor
|
|
EP3536690A1
(en)
|
2007-01-10 |
2019-09-11 |
MSD Italia S.r.l. |
Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
|
|
ES2319029B1
(es)
*
|
2007-02-09 |
2010-02-10 |
Universidad De Almeria |
Proceso para la produccion en continuo de lovastatina.
|
|
EA019951B1
(ru)
|
2007-03-01 |
2014-07-30 |
Новартис Аг |
Ингибиторы киназы pim и способы их применения
|
|
US20090326013A1
(en)
*
|
2007-03-01 |
2009-12-31 |
Curt Hendrix |
Isomers of inositol niacinate and uses thereof
|
|
WO2008112887A1
(en)
*
|
2007-03-13 |
2008-09-18 |
Musc Foundation For Research Development |
Methods of treating juvenile type 1 diabetes mellitus
|
|
TW200904405A
(en)
|
2007-03-22 |
2009-02-01 |
Bristol Myers Squibb Co |
Pharmaceutical formulations containing an SGLT2 inhibitor
|
|
WO2008124121A1
(en)
*
|
2007-04-06 |
2008-10-16 |
Scidose, Llc |
Co-therapy with and combinations of statins and 1,4-dihydropyridine-3,5-dicarboxydiesters
|
|
AP2009005026A0
(en)
*
|
2007-04-09 |
2009-12-31 |
Scidose Llc |
Combinations of statins and anti-obesity agent
|
|
WO2008124122A1
(en)
*
|
2007-04-09 |
2008-10-16 |
Scidose, Llc |
Combinations of statins and anti-obesity agent and glitazones
|
|
EP2474549A1
(en)
|
2007-04-17 |
2012-07-11 |
Bristol-Myers Squibb Company |
Fused heterocyclic 11-beta-hydroxysteroid dehydrogenase type I inhibitors
|
|
TW200849035A
(en)
|
2007-04-18 |
2008-12-16 |
Tethys Bioscience Inc |
Diabetes-related biomarkers and methods of use thereof
|
|
PE20090696A1
(es)
|
2007-04-20 |
2009-06-20 |
Bristol Myers Squibb Co |
Formas cristalinas de saxagliptina y procesos para preparar las mismas
|
|
CA2685054C
(en)
|
2007-04-27 |
2014-11-04 |
Kyushu University, National University Corporation |
Agent for treatment of pulmonary disease
|
|
EP2147008A2
(en)
*
|
2007-05-18 |
2010-01-27 |
Bristol-Myers Squibb Company |
Crystal structures of sglt2 inhibitors and processes for preparing same
|
|
US8293769B2
(en)
|
2007-05-21 |
2012-10-23 |
Novartis Ag |
CSF-1R inhibitors, compositions, and methods of use
|
|
IN2009KN04568A
(enExample)
|
2007-06-01 |
2015-08-28 |
Univ Princeton |
|
|
DE102007028320A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
|
DE102007028406A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
|
DE102007028319A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
|
DE102007028407A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
|
EP2170076B1
(en)
|
2007-06-27 |
2016-05-18 |
Merck Sharp & Dohme Corp. |
4-carboxybenzylamino derivatives as histone deacetylase inhibitors
|
|
US20090011994A1
(en)
*
|
2007-07-06 |
2009-01-08 |
Bristol-Myers Squibb Company |
Non-basic melanin concentrating hormone receptor-1 antagonists and methods
|
|
JP2010534722A
(ja)
*
|
2007-07-27 |
2010-11-11 |
ブリストル−マイヤーズ スクイブ カンパニー |
新規グルコキナーゼ活性化薬およびその使用方法
|
|
JOP20080381B1
(ar)
|
2007-08-23 |
2023-03-28 |
Amgen Inc |
بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
|
|
MX2010003117A
(es)
*
|
2007-09-20 |
2010-04-01 |
Irm Llc |
Compuestos y composiciones como moduladores de la actividad de gpr119.
|
|
ES2448839T3
(es)
|
2007-11-01 |
2014-03-17 |
Bristol-Myers Squibb Company |
Compuestos no esteroideos útiles como moderadores de la actividad del receptor de glucocorticoides AP-1 y/o NF-kappa b y uso de los mismos
|
|
WO2009078033A2
(en)
*
|
2007-12-18 |
2009-06-25 |
Themis Medicare Limited |
Isolation and recovery of simvastatin in lactone form or in the form of an acid salt from the harvested fermentation broth
|
|
CA2709677C
(en)
|
2007-12-21 |
2017-03-14 |
Lin Zhi |
Selective androgen receptor modulators (sarms) and uses thereof
|
|
ME03529B
(me)
|
2008-01-11 |
2020-04-20 |
Reata Pharmaceuticals Inc |
Sintetički triterpenoidi i metode njihove upotrebe u tretmanu bolesti
|
|
US20110112053A1
(en)
*
|
2008-04-16 |
2011-05-12 |
University Of Utah Research Foundation |
Pharmacological targeting of vascular malformations
|
|
US9072727B2
(en)
|
2008-04-18 |
2015-07-07 |
Warsaw Orthopedic, Inc. |
Alpha adrenergic receptor agonists for treatment of degenerative disc disease
|
|
US8420114B2
(en)
|
2008-04-18 |
2013-04-16 |
Warsaw Orthopedic, Inc. |
Alpha and beta adrenergic receptor agonists for treatment of pain and / or inflammation
|
|
US8557273B2
(en)
|
2008-04-18 |
2013-10-15 |
Medtronic, Inc. |
Medical devices and methods including polymers having biologically active agents therein
|
|
PE20091928A1
(es)
*
|
2008-05-29 |
2009-12-31 |
Bristol Myers Squibb Co |
Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
|
|
ES2330184B1
(es)
|
2008-06-03 |
2010-07-05 |
Neuron Biopharma, S.A. |
Uso de estatinas como anticonvulsivantes, antiepilepticos y neuroprotectores.
|
|
EP2138178A1
(en)
|
2008-06-28 |
2009-12-30 |
Bayer Schering Pharma Aktiengesellschaft |
Oxazolidninones for the treatment fo chronic obstructive pulmonary disease (COPD) and/or asthma
|
|
EP2161024A1
(de)
|
2008-09-05 |
2010-03-10 |
Universitätsklinikum Hamburg-Eppendorf |
Kombinationspräparat zur Behandlung von Krebs
|
|
US20120046364A1
(en)
|
2009-02-10 |
2012-02-23 |
Metabasis Therapeutics, Inc. |
Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
|
|
KR20110135411A
(ko)
|
2009-03-27 |
2011-12-16 |
브리스톨-마이어스 스큅 컴퍼니 |
Dpp-iv 억제제로 주요 유해 심장혈관 이벤트를 예방하는 방법
|
|
WO2010114780A1
(en)
|
2009-04-01 |
2010-10-07 |
Merck Sharp & Dohme Corp. |
Inhibitors of akt activity
|
|
US8470805B2
(en)
*
|
2009-04-30 |
2013-06-25 |
Kaohsiung Medical University |
Processes for preparing piperazinium salts of KMUP and use thereof
|
|
AU2010254082B2
(en)
|
2009-05-28 |
2015-01-29 |
Exelixis, Inc. |
LXR modulators
|
|
EP2440058A4
(en)
|
2009-06-12 |
2012-11-21 |
Dana Farber Cancer Inst Inc |
MELTED HETEROCYCLIC COMPOUNDS AND APPLICATIONS THEREOF
|
|
WO2011014520A2
(en)
|
2009-07-29 |
2011-02-03 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
|
JP2013507366A
(ja)
|
2009-10-09 |
2013-03-04 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
Gpr119活性モジュレーターとしての化合物および組成物
|
|
WO2011046771A1
(en)
|
2009-10-14 |
2011-04-21 |
Schering Corporation |
SUBSTITUTED PIPERIDINES THAT INCREASE p53 ACTIVITY AND THE USES THEREOF
|
|
HRP20181347T1
(hr)
|
2009-11-13 |
2018-10-19 |
Astrazeneca Ab |
Formulacije dvoslojne tablete
|
|
CA3002948C
(en)
|
2009-11-13 |
2020-10-27 |
Astrazeneca Uk Limited |
Immediate release tablet formulations
|
|
CN102711738A
(zh)
|
2009-11-13 |
2012-10-03 |
百时美施贵宝公司 |
质量得以减小的二甲双胍制剂
|
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
|
US20130115622A1
(en)
|
2009-12-14 |
2013-05-09 |
Kyoto University |
Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis
|
|
AU2010343102B2
(en)
|
2009-12-29 |
2016-03-24 |
Dana-Farber Cancer Institute, Inc. |
Type II Raf kinase inhibitors
|
|
CN103037829A
(zh)
|
2010-02-01 |
2013-04-10 |
儿童医院 |
用于治疗和预防再狭窄的远程缺血调节
|
|
TWI562775B
(en)
|
2010-03-02 |
2016-12-21 |
Lexicon Pharmaceuticals Inc |
Methods of using inhibitors of sodium-glucose cotransporters 1 and 2
|
|
MX2012010617A
(es)
|
2010-03-16 |
2012-10-05 |
Dana Farber Cancer Inst Inc |
Compuestos de imidazol y sus usos.
|
|
SG10201908570RA
(en)
|
2010-03-31 |
2019-11-28 |
Hospital For Sick Children |
Use of remote ischemic conditioning to improve outcome after myocardial infarction
|
|
US9393025B2
(en)
|
2010-04-08 |
2016-07-19 |
The Hospital For Sick Children |
Use of remote ischemic conditioning for traumatic injury
|
|
JP2013523894A
(ja)
|
2010-04-14 |
2013-06-17 |
ブリストル−マイヤーズ スクイブ カンパニー |
新規グルコキナーゼアクチベーターおよびその使用方法
|
|
US8372877B2
(en)
|
2010-04-16 |
2013-02-12 |
Cumberland Pharmaceuticals |
Stabilized statin formulations
|
|
CA2799708A1
(en)
|
2010-05-21 |
2011-11-24 |
Pfizer Inc. |
2-phenyl benzoylamides
|
|
US8999957B2
(en)
|
2010-06-24 |
2015-04-07 |
Merck Sharp & Dohme Corp. |
Heterocyclic compounds as ERK inhibitors
|
|
JP6042330B2
(ja)
|
2010-07-09 |
2016-12-14 |
ビーエイチヴィ ファーマ、インコーポレイテッド |
レモグリフロジンを含めた半減期が短い医薬品のための組合せ即時/遅延放出送達システム
|
|
US8697739B2
(en)
|
2010-07-29 |
2014-04-15 |
Novartis Ag |
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
|
|
AU2011285909B2
(en)
|
2010-08-02 |
2016-11-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA)
|
|
EP4079856A1
(en)
|
2010-08-17 |
2022-10-26 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of hepatitis b virus (hbv) gene expression using short interfering nucleic acid (sina)
|
|
EP2608669B1
(en)
|
2010-08-23 |
2016-06-22 |
Merck Sharp & Dohme Corp. |
NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
|
|
US20130156720A1
(en)
|
2010-08-27 |
2013-06-20 |
Ironwood Pharmaceuticals, Inc. |
Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
|
|
WO2012030685A2
(en)
|
2010-09-01 |
2012-03-08 |
Schering Corporation |
Indazole derivatives useful as erk inhibitors
|
|
EP2615916B1
(en)
|
2010-09-16 |
2017-01-04 |
Merck Sharp & Dohme Corp. |
Fused pyrazole derivatives as novel erk inhibitors
|
|
US20130210860A1
(en)
|
2010-10-06 |
2013-08-15 |
Kowa Co., Ltd. |
Prophylactic and/or therapeutic agent against lymphedema
|
|
EP3327125B1
(en)
|
2010-10-29 |
2020-08-05 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of gene expression using short interfering nucleic acids (sina)
|
|
TWI462739B
(zh)
|
2010-11-02 |
2014-12-01 |
Univ Kaohsiung Medical |
Sildenafil-同族物四級銨哌嗪鹽類之製備及醫療用途
|
|
US9351965B2
(en)
|
2010-12-21 |
2016-05-31 |
Merck Sharp & Dohme Corp. |
Indazole derivatives useful as ERK inhibitors
|
|
TWI631963B
(zh)
|
2011-01-05 |
2018-08-11 |
雷西肯製藥股份有限公司 |
包含鈉-葡萄糖共同輸送體1與2之抑制劑的組合物與應用方法
|
|
US10017470B2
(en)
|
2011-01-31 |
2018-07-10 |
Cadila Healthcare Limited |
Treatment for lipodystrophy
|
|
EP2675440B1
(en)
|
2011-02-14 |
2020-03-25 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
|
WO2012120414A2
(en)
|
2011-03-04 |
2012-09-13 |
Pfizer Inc. |
Edn3-like peptides and uses thereof
|
|
AR088728A1
(es)
|
2011-03-25 |
2014-07-02 |
Bristol Myers Squibb Co |
Moduladores de lxr como prodroga de imidazol
|
|
WO2012145471A1
(en)
|
2011-04-21 |
2012-10-26 |
Merck Sharp & Dohme Corp. |
Insulin-like growth factor-1 receptor inhibitors
|
|
EP2770987B1
(en)
|
2011-10-27 |
2018-04-04 |
Merck Sharp & Dohme Corp. |
Novel compounds that are erk inhibitors
|
|
JP6106685B2
(ja)
|
2011-11-17 |
2017-04-05 |
ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド |
C−jun−n−末端キナーゼ(jnk)の阻害剤
|
|
EP2597092A1
(en)
|
2011-11-24 |
2013-05-29 |
Sterling Biotech Limited |
A process for purification of lovastatin
|
|
US20150010630A1
(en)
|
2011-12-29 |
2015-01-08 |
Trustees Of Tufts College |
Functionalization of biomaterials to control regeneration and inflammation responses
|
|
JP6224624B2
(ja)
|
2012-02-02 |
2017-11-01 |
ザ・ユニバーシティ・オブ・シドニー |
涙膜安定性における改善
|
|
EP3453762B1
(en)
|
2012-05-02 |
2021-04-21 |
Sirna Therapeutics, Inc. |
Short interfering nucleic acid (sina) compositions
|
|
WO2013167669A1
(en)
|
2012-05-10 |
2013-11-14 |
Bayer Pharma Aktiengesellschaft |
Antibodies capable of binding to the coagulation factor xi and/or its activated form factor xia and uses thereof
|
|
NZ728724A
(en)
|
2012-05-11 |
2018-03-23 |
Reset Therapeutics Inc |
Carbazole-containing sulfonamides as cryptochrome modulators
|
|
CA2881563C
(en)
|
2012-08-01 |
2021-07-20 |
Zahra TAVAKOLI |
Free flowing, frozen compositions comprising a therapeutic agent
|
|
CN102875505B
(zh)
*
|
2012-08-02 |
2015-08-05 |
丽珠集团新北江制药股份有限公司 |
一种美伐他汀的提取精制工艺
|
|
WO2014052619A1
(en)
|
2012-09-27 |
2014-04-03 |
Irm Llc |
Piperidine derivatives and compositions as modulators of gpr119 activity
|
|
AU2013323508B2
(en)
|
2012-09-28 |
2017-11-02 |
Merck Sharp & Dohme Corp. |
Novel compounds that are ERK inhibitors
|
|
JP6218084B2
(ja)
|
2012-10-04 |
2017-10-25 |
国立研究開発法人国立循環器病研究センター |
悪性腫瘍転移抑制用医薬
|
|
US10112927B2
(en)
|
2012-10-18 |
2018-10-30 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 (CDK7)
|
|
WO2014063054A1
(en)
|
2012-10-19 |
2014-04-24 |
Dana-Farber Cancer Institute, Inc. |
Bone marrow on x chromosome kinase (bmx) inhibitors and uses thereof
|
|
WO2014063061A1
(en)
|
2012-10-19 |
2014-04-24 |
Dana-Farber Cancer Institute, Inc. |
Hydrophobically tagged small molecules as inducers of protein degradation
|
|
RU2015123738A
(ru)
|
2012-11-20 |
2017-01-10 |
Лексикон Фармасьютикалз, Инк. |
Ингибиторы котранспортера натрий-глюкозы 1
|
|
EP2925888B1
(en)
|
2012-11-28 |
2017-10-25 |
Merck Sharp & Dohme Corp. |
Compositions and methods for treating cancer
|
|
CA2895504A1
(en)
|
2012-12-20 |
2014-06-26 |
Merck Sharp & Dohme Corp. |
Substituted imidazopyridines as hdm2 inhibitors
|
|
EP2951180B1
(en)
|
2013-01-30 |
2018-05-02 |
Merck Sharp & Dohme Corp. |
2,6,7,8 substituted purines as hdm2 inhibitors
|
|
EP2968275B1
(en)
|
2013-03-15 |
2017-11-29 |
Bristol-Myers Squibb Company |
Lxr modulators
|
|
IL287731B2
(en)
|
2013-03-21 |
2025-05-01 |
Eupraxia Pharmaceuticals USA LLC |
A sustained-release preparation for injection for the treatment of arthritis and resulting pain
|
|
CN105143203A
(zh)
|
2013-04-17 |
2015-12-09 |
辉瑞大药厂 |
用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
|
|
EA201592020A1
(ru)
|
2013-04-22 |
2016-05-31 |
Кадила Хелзкэр Лимитед |
Новая композиция для неалкогольной жировой болезни печени (нажбп)
|
|
PH12015502667B1
(en)
|
2013-05-30 |
2023-10-18 |
Zydus Lifesciences Ltd |
A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
|
|
EP2810644A1
(en)
|
2013-06-06 |
2014-12-10 |
Ferrer Internacional, S.A. |
Oral formulation for the treatment of cardiovascular diseases
|
|
TW201636015A
(zh)
|
2013-07-05 |
2016-10-16 |
卡地拉保健有限公司 |
協同性組成物
|
|
IN2013MU02470A
(enExample)
|
2013-07-25 |
2015-06-26 |
Cadila Healthcare Ltd |
|
|
WO2015027021A1
(en)
|
2013-08-22 |
2015-02-26 |
Bristol-Myers Squibb Company |
Imide and acylurea derivatives as modulators of the glucocorticoid receptor
|
|
WO2015034925A1
(en)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
|
IN2013MU02905A
(enExample)
|
2013-09-06 |
2015-07-03 |
Cadila Healthcare Ltd |
|
|
WO2015051479A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
|
CA2923272A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
|
EP3057956B1
(en)
|
2013-10-18 |
2021-05-05 |
Dana-Farber Cancer Institute, Inc. |
Polycyclic inhibitors of cyclin-dependent kinase 7 (cdk7)
|
|
EP3057955B1
(en)
|
2013-10-18 |
2018-04-11 |
Syros Pharmaceuticals, Inc. |
Heteroaromatic compounds useful for the treatment of prolferative diseases
|
|
JP6536871B2
(ja)
|
2013-12-02 |
2019-07-03 |
国立大学法人京都大学 |
Fgfr3病の予防および治療剤ならびにそのスクリーニング方法
|
|
EP3094323A4
(en)
|
2014-01-17 |
2017-10-11 |
Ligand Pharmaceuticals Incorporated |
Methods and compositions for modulating hormone levels
|
|
WO2015120580A1
(en)
|
2014-02-11 |
2015-08-20 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
|
TWI690521B
(zh)
|
2014-04-07 |
2020-04-11 |
美商同步製藥公司 |
作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類
|
|
US9862688B2
(en)
|
2014-04-23 |
2018-01-09 |
Dana-Farber Cancer Institute, Inc. |
Hydrophobically tagged janus kinase inhibitors and uses thereof
|
|
WO2015164614A1
(en)
|
2014-04-23 |
2015-10-29 |
Dana-Farber Cancer Institute, Inc. |
Janus kinase inhibitors and uses thereof
|
|
JO3589B1
(ar)
|
2014-08-06 |
2020-07-05 |
Novartis Ag |
مثبطات كيناز البروتين c وطرق استخداماتها
|
|
EP3808367A3
(en)
|
2014-09-15 |
2021-07-21 |
The Board of Trustees of the Leland Stanford Junior University |
Targeting aneurysm disease by modulating phagocytosis pathways
|
|
WO2016055901A1
(en)
|
2014-10-08 |
2016-04-14 |
Pfizer Inc. |
Substituted amide compounds
|
|
CA2972239A1
(en)
|
2014-12-23 |
2016-06-30 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 (cdk7)
|
|
US11253588B2
(en)
|
2015-02-27 |
2022-02-22 |
The Board Of Trustees Of The Leland Stanford Junior University |
Combination therapy for treatment of coronary artery disease
|
|
CN107427521B
(zh)
|
2015-03-27 |
2021-08-03 |
达纳-法伯癌症研究所股份有限公司 |
细胞周期蛋白依赖性激酶的抑制剂
|
|
US10736871B2
(en)
|
2015-04-01 |
2020-08-11 |
Cedars-Sinai Medical Center |
Anti-methanogenic lovastatin analogs or derivatives and uses thereof
|
|
US10987670B2
(en)
|
2015-04-14 |
2021-04-27 |
President And Fellows Of Harvard College |
Electrode array for vortex-assisted electroporation
|
|
KR20170138570A
(ko)
|
2015-04-30 |
2017-12-15 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
대사 장애를 치료하기 위한 항-aP2 항체 및 항원 결합 물질
|
|
WO2016201370A1
(en)
|
2015-06-12 |
2016-12-15 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy of transcription inhibitors and kinase inhibitors
|
|
EP4019515A1
(en)
|
2015-09-09 |
2022-06-29 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinases
|
|
US10385017B2
(en)
|
2015-10-14 |
2019-08-20 |
Cadila Healthcare Limited |
Pyrrole compound, compositions and process for preparation thereof
|
|
SG11201803156TA
(en)
|
2015-10-27 |
2018-05-30 |
Eupraxia Pharmaceuticals Inc |
Sustained release formulations of local anesthetics
|
|
EP3525785B1
(en)
|
2016-10-12 |
2025-08-27 |
Merck Sharp & Dohme LLC |
Kdm5 inhibitors
|
|
JP6840853B2
(ja)
|
2016-12-09 |
2021-03-10 |
カディラ・ヘルスケア・リミテッド |
原発性胆汁性胆管炎の治療
|
|
US20200129440A1
(en)
|
2017-01-23 |
2020-04-30 |
Dong Wha Pharm. Co., Ltd. |
Complex formulation comprising hmg-coa reductase inhibitor and clopidogrel
|
|
AU2018277083A1
(en)
|
2017-05-30 |
2019-12-05 |
The Board Of Trustees Of The Leland Stanford Junior University |
Treatment of neuroinflammatory disease
|
|
US20200345701A1
(en)
|
2017-11-02 |
2020-11-05 |
Consejo Superior De Investigaciones Cientificas (Csic) |
Use of statins in overcoming resistance to beta-lactam antibiotics in bacterial species synthetizing isoprenoids using the mevalonate synthetic pathway
|
|
EP3706742B1
(en)
|
2017-11-08 |
2023-03-15 |
Merck Sharp & Dohme LLC |
Prmt5 inhibitors
|
|
US11098059B2
(en)
|
2017-11-08 |
2021-08-24 |
Merck Sharp & Dohme Corp. |
PRMT5 inhibitors
|
|
JP7590185B2
(ja)
|
2018-06-25 |
2024-11-26 |
ダナ-ファーバー キャンサー インスティテュート, インコーポレイテッド |
Taireファミリーキナーゼインヒビターおよびそれらの使用
|
|
SG11202100417RA
(en)
|
2018-07-19 |
2021-02-25 |
Astrazeneca Ab |
Methods of treating hfpef employing dapagliflozin and compositions comprising the same
|
|
EP3824912A4
(en)
|
2018-07-19 |
2022-04-20 |
Kyoto University |
PLATEFORM CARTILAGE DERIVED FROM PLURIPOTENTS STEM CELLS AND METHODS FOR PRODUCTION OF PLATEFORM CARTILAGE
|
|
WO2020033288A1
(en)
|
2018-08-07 |
2020-02-13 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
|
US11981701B2
(en)
|
2018-08-07 |
2024-05-14 |
Merck Sharp & Dohme Llc |
PRMT5 inhibitors
|
|
EP3833668B1
(en)
|
2018-08-07 |
2025-03-19 |
Merck Sharp & Dohme LLC |
Prmt5 inhibitors
|
|
CA3113037A1
(en)
|
2018-09-26 |
2020-04-02 |
Lexicon Pharmaceuticals, Inc. |
Crystalline forms of n-(1-((2-(dimethylamino)ethyl)amino)-2-methyl-1-oopropan-2-yl)-4-(4-(2-methyl-5-(2s,3r,4r,5s,6r)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2h-pyran-2-yl)benzyl)phenl)butanamide and methods of their synthesis
|
|
US12435311B2
(en)
|
2018-12-21 |
2025-10-07 |
The University Of Osaka |
Lubricin-localized cartilage-like tissue, method for producing same and composition comprising same for treating articular cartilage damage
|
|
EP3902542A4
(en)
|
2018-12-28 |
2022-09-07 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 and uses thereof
|
|
CN119060040A
(zh)
|
2019-01-18 |
2024-12-03 |
阿斯利康(瑞典)有限公司 |
Pcsk9抑制剂及其使用方法
|
|
CA3133929A1
(en)
|
2019-04-19 |
2020-10-22 |
Lin Zhi |
Crystalline forms and methods of producing crystalline forms of a compound
|
|
AU2020283500A1
(en)
|
2019-05-27 |
2022-01-27 |
Immatics US, Inc. |
Viral vectors and their use in adoptive cellular therapy
|
|
US20230108452A1
(en)
|
2019-12-17 |
2023-04-06 |
Merck Sharp & Dohme Llc |
Prmt5 inhibitors
|
|
WO2021126728A1
(en)
|
2019-12-17 |
2021-06-24 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
|
WO2021126729A1
(en)
|
2019-12-17 |
2021-06-24 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
|
JPWO2021167088A1
(enExample)
|
2020-02-21 |
2021-08-26 |
|
|
|
DE102020111571A1
(de)
|
2020-03-11 |
2021-09-16 |
Immatics US, Inc. |
Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
|
|
TW202220672A
(zh)
|
2020-07-27 |
2022-06-01 |
瑞典商阿斯特捷利康公司 |
用達格列淨治療慢性腎臟病之方法
|
|
EP4188372A1
(en)
|
2020-07-29 |
2023-06-07 |
Amryt Pharmaceuticals Inc. |
Lomitapide for use in methods of treating hyperlipidemia and hypercholesterolemia in pediatric patients
|
|
US20220056411A1
(en)
|
2020-08-21 |
2022-02-24 |
Immatics US, Inc. |
Methods for isolating cd8+ selected t cells
|
|
JP2025503136A
(ja)
|
2022-01-26 |
2025-01-30 |
アストラゼネカ・アクチエボラーグ |
前糖尿病の治療又は2型糖尿病の発症リスクを低減する際に使用するためのダパグリフロジン
|
|
WO2024180169A1
(en)
|
2023-03-02 |
2024-09-06 |
Carcimun Biotech Gmbh |
Means and methods for diagnosing cancer and/or an acute inflammatory disease
|
|
WO2025147589A1
(en)
|
2024-01-05 |
2025-07-10 |
Osanni Bio, Inc. |
Implants, compositions, and methods for treating retinal diseases and disorders
|
|
WO2025168652A1
(en)
|
2024-02-05 |
2025-08-14 |
Astrazeneca Ab |
Azd-0780 in combination with a statin for use in lowering ldl-c levels and treating cardiovacular diseases
|
|
WO2025196153A1
(en)
|
2024-03-20 |
2025-09-25 |
Astrazeneca Ab |
Pcsk9 inhibitors and methods of use thereof
|
|
WO2025196155A1
(en)
|
2024-03-20 |
2025-09-25 |
Astrazeneca Ab |
Pcsk9 inhibitors and methods of use thereof
|
|
WO2025196154A1
(en)
|
2024-03-20 |
2025-09-25 |
Astrazeneca Ab |
Pcsk9 inhibitors and methods of use thereof
|
|
WO2025238159A1
(en)
|
2024-05-16 |
2025-11-20 |
Astrazeneca Ab |
Combination therapy comprising azd0780 and ezetimibe
|