ZA200206712B - Humanized antibodies that sequester amyloid beta peptide. - Google Patents

Info

Publication number

ZA200206712B

ZA200206712B ZA200206712A ZA200206712A ZA200206712B ZA 200206712 B ZA200206712 B ZA 200206712B ZA 200206712 A ZA200206712 A ZA 200206712A ZA 200206712 A ZA200206712 A ZA 200206712A ZA 200206712 B ZA200206712 B ZA 200206712B

Authority

ZA

South Africa

Prior art keywords

ser

val

xaa

antibody

gly

Prior art date

2000-02-24

Links

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• 102000013455 Amyloid beta-Peptides Human genes 0.000 title description 94
• 239000012634 fragment Substances 0.000 claims description 77
• 238000000034 method Methods 0.000 claims description 52
• 150000001413 amino acids Chemical group 0.000 claims description 50
• 210000004027 cell Anatomy 0.000 claims description 36
• 108060003951 Immunoglobulin Proteins 0.000 claims description 31
• 102000018358 immunoglobulin Human genes 0.000 claims description 31
• 239000000203 mixture Substances 0.000 claims description 27
• 108091033319 polynucleotide Proteins 0.000 claims description 26
• 102000040430 polynucleotide Human genes 0.000 claims description 26
• 208000024827 Alzheimer disease Diseases 0.000 claims description 21
• 238000011282 treatment Methods 0.000 claims description 19
• 239000013598 vector Substances 0.000 claims description 17
• 239000002157 polynucleotide Substances 0.000 claims description 16
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• 206010044688 Trisomy 21 Diseases 0.000 claims description 15
• 239000000126 substance Substances 0.000 claims description 13
• 208000005145 Cerebral amyloid angiopathy Diseases 0.000 claims description 12
• 108010047041 Complementarity Determining Regions Proteins 0.000 claims description 12
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