UA80393C2 - Фармацевтическая композиция, которая содержит ингибитор фдэ 4, диспергированный в матрице - Google Patents

Фармацевтическая композиция, которая содержит ингибитор фдэ 4, диспергированный в матрице Download PDF

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Publication number
UA80393C2
UA80393C2 UA2003076286A UA2003076286A UA80393C2 UA 80393 C2 UA80393 C2 UA 80393C2 UA 2003076286 A UA2003076286 A UA 2003076286A UA 2003076286 A UA2003076286 A UA 2003076286A UA 80393 C2 UA80393 C2 UA 80393C2
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Ukraine
Prior art keywords
sodium
acid
composition according
droplets
excipients
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UA2003076286A
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English (en)
Ukrainian (uk)
Inventor
Ранго Дітріх
Рудольф Ліндер
Хартмут Ней
Original Assignee
Алтана Фарма Аг
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Application filed by Алтана Фарма Аг filed Critical Алтана Фарма Аг
Publication of UA80393C2 publication Critical patent/UA80393C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Данное изобретение относится к области фармацевтической технологии и касается новой композиции, которая содержит действующее вещество, выбранное из группы ингибиторов ФДЭ 4. В новой композиции действующее вещество практически однородно диспергировано в матрице эксципиента, которая содержит один или несколько эксципиентов, выбранных из группы, включающей жирный спирт, триглицерид, неполный глицерид и эфир жирной кислоты, и при этом композиция находится в форме, которая состоит из микросфер.
UA2003076286A 2000-12-07 2001-06-12 Фармацевтическая композиция, которая содержит ингибитор фдэ 4, диспергированный в матрице UA80393C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00126847 2000-12-07
PCT/EP2001/014307 WO2002045693A1 (en) 2000-12-07 2001-12-06 Pharmaceutical preparation comprising an active dispersed on a matrix

Publications (1)

Publication Number Publication Date
UA80393C2 true UA80393C2 (ru) 2007-09-25

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ID=8170601

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2003076286A UA80393C2 (ru) 2000-12-07 2001-06-12 Фармацевтическая композиция, которая содержит ингибитор фдэ 4, диспергированный в матрице

Country Status (28)

Country Link
US (2) US7175854B2 (ru)
EP (1) EP1341527B1 (ru)
JP (1) JP4950409B2 (ru)
KR (1) KR20030072557A (ru)
CN (2) CN101810592A (ru)
AT (1) ATE519481T1 (ru)
AU (2) AU1607302A (ru)
BR (1) BR0115987A (ru)
CA (1) CA2430828C (ru)
CY (1) CY1112333T1 (ru)
CZ (1) CZ20031881A3 (ru)
DK (1) DK1341527T3 (ru)
EA (1) EA007151B1 (ru)
EE (1) EE05256B1 (ru)
ES (1) ES2371060T3 (ru)
HR (1) HRP20030493B1 (ru)
HU (1) HUP0400566A3 (ru)
IL (2) IL155964A0 (ru)
MX (1) MXPA03005092A (ru)
NO (1) NO333722B1 (ru)
NZ (1) NZ526015A (ru)
PL (1) PL206595B1 (ru)
PT (1) PT1341527E (ru)
SG (1) SG148028A1 (ru)
SI (1) SI1341527T1 (ru)
UA (1) UA80393C2 (ru)
WO (1) WO2002045693A1 (ru)
ZA (1) ZA200305114B (ru)

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