TWI437996B - 含有sglt抑制劑及dpp4抑制劑之醫藥組成物 - Google Patents

含有sglt抑制劑及dpp4抑制劑之醫藥組成物 Download PDF

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Publication number
TWI437996B
TWI437996B TW098101763A TW98101763A TWI437996B TW I437996 B TWI437996 B TW I437996B TW 098101763 A TW098101763 A TW 098101763A TW 98101763 A TW98101763 A TW 98101763A TW I437996 B TWI437996 B TW I437996B
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Taiwan
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group
alkyl
inhibitor
disease
cyano
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TW098101763A
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Chinese (zh)
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TW200932249A (en
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Kiichiro Ueta
Kenji Arakawa
Yasuaki Matsushita
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Mitsubishi Tanabe Pharma Corp
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
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    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/7008Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • AHUMAN NECESSITIES
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    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
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    • C07H7/00Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Biomedical Technology (AREA)
  • Diabetes (AREA)
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  • Neurology (AREA)
  • Obesity (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW098101763A 2008-01-17 2009-01-17 含有sglt抑制劑及dpp4抑制劑之醫藥組成物 TWI437996B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2177708P 2008-01-17 2008-01-17

Publications (2)

Publication Number Publication Date
TW200932249A TW200932249A (en) 2009-08-01
TWI437996B true TWI437996B (zh) 2014-05-21

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ID=40433628

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TW098101763A TWI437996B (zh) 2008-01-17 2009-01-17 含有sglt抑制劑及dpp4抑制劑之醫藥組成物

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Country Link
US (2) US8853385B2 (https=)
EP (1) EP2252289B1 (https=)
JP (3) JP5204849B2 (https=)
KR (1) KR101257554B1 (https=)
CN (2) CN101932321B (https=)
AR (1) AR070193A1 (https=)
AU (1) AU2009205060C1 (https=)
BR (1) BRPI0906735A2 (https=)
CA (1) CA2712614C (https=)
CL (1) CL2008003653A1 (https=)
ES (1) ES2763239T3 (https=)
MX (1) MX2010007818A (https=)
TW (1) TWI437996B (https=)
WO (1) WO2009091082A1 (https=)

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AU2009205060B2 (en) 2013-06-27
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CN101932321B (zh) 2016-05-18
BRPI0906735A2 (pt) 2015-07-07
AR070193A1 (es) 2010-03-17
KR20100103874A (ko) 2010-09-28
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JP5908563B2 (ja) 2016-04-26
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