TW201817745A - 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子 - Google Patents
具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子 Download PDFInfo
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- A61P37/02—Immunomodulators
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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Landscapes
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| PCT/JP2012/058603 WO2012133782A1 (ja) | 2011-03-30 | 2012-03-30 | 抗原結合分子の血漿中滞留性と免疫原性を改変する方法 |
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| TW101135493A TW201326209A (zh) | 2011-09-30 | 2012-09-27 | 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子 |
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| CN104761637B (zh) | 2006-03-31 | 2021-10-15 | 中外制药株式会社 | 调控抗体血液动力学的方法 |
| TWI464262B (zh) | 2007-09-26 | 2014-12-11 | 中外製藥股份有限公司 | 抗體固定區的變異 |
| CN101874042B9 (zh) | 2007-09-26 | 2019-01-01 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
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2012
- 2012-09-27 TW TW107101835A patent/TW201817745A/zh unknown
- 2012-09-27 TW TW107101834A patent/TW201817744A/zh unknown
- 2012-09-27 TW TW101135493A patent/TW201326209A/zh unknown
- 2012-09-28 MX MX2014003891A patent/MX2014003891A/es unknown
- 2012-09-28 CN CN201810780566.9A patent/CN108948197A/zh not_active Withdrawn
- 2012-09-28 EP EP23210057.8A patent/EP4324850A3/en active Pending
- 2012-09-28 CN CN201280058760.7A patent/CN103958547B/zh not_active Expired - Fee Related
- 2012-09-28 SG SG10201808187TA patent/SG10201808187TA/en unknown
- 2012-09-28 US US14/347,187 patent/US10253100B2/en active Active
- 2012-09-28 CA CA2850035A patent/CA2850035A1/en not_active Abandoned
- 2012-09-28 EP EP19150272.3A patent/EP3549956A3/en not_active Withdrawn
- 2012-09-28 RU RU2018118993A patent/RU2018118993A/ru not_active Application Discontinuation
- 2012-09-28 EP EP12775324.2A patent/EP2760890B1/en active Active
- 2012-09-28 WO PCT/JP2012/006218 patent/WO2013046704A2/en not_active Ceased
- 2012-09-28 BR BR112014007290A patent/BR112014007290A2/pt active Search and Examination
- 2012-09-28 KR KR1020147011698A patent/KR20140069332A/ko not_active Withdrawn
- 2012-09-28 AU AU2012313670A patent/AU2012313670B2/en not_active Ceased
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- 2012-09-28 JP JP2014514947A patent/JP6204350B2/ja active Active
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- 2017-08-31 JP JP2017166638A patent/JP6541730B2/ja active Active
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2019
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