TW201817745A - 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子 - Google Patents
具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子 Download PDFInfo
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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| JP2011218736 | 2011-09-30 | ||
| JP2011-218736 | 2011-09-30 | ||
| PCT/JP2012/058603 WO2012133782A1 (ja) | 2011-03-30 | 2012-03-30 | 抗原結合分子の血漿中滞留性と免疫原性を改変する方法 |
| ??PCT/JP2012/058603 | 2012-03-30 | ||
| JP2012123781 | 2012-05-30 | ||
| JP2012-123782 | 2012-05-30 | ||
| JP2012-123781 | 2012-05-30 | ||
| JP2012-123773 | 2012-05-30 | ||
| JP2012123773 | 2012-05-30 | ||
| JP2012123782 | 2012-05-30 | ||
| JP2012-139211 | 2012-06-20 | ||
| JP2012139211 | 2012-06-20 | ||
| JP2012177311 | 2012-08-09 | ||
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| TW107101834A TW201817744A (zh) | 2011-09-30 | 2012-09-27 | 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子 |
| TW107101835A TW201817745A (zh) | 2011-09-30 | 2012-09-27 | 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子 |
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| TW107101834A TW201817744A (zh) | 2011-09-30 | 2012-09-27 | 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子 |
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| CA2647846C (en) | 2006-03-31 | 2016-06-21 | Chugai Seiyaku Kabushiki Kaisha | Methods for controlling blood pharmacokinetics of antibodies |
| CN106519025B (zh) | 2007-09-26 | 2021-04-23 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
| KR102339457B1 (ko) | 2007-09-26 | 2021-12-14 | 추가이 세이야쿠 가부시키가이샤 | 항체 정상영역 개변체 |
| CA2721052C (en) | 2008-04-11 | 2023-02-21 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
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2012
- 2012-09-27 TW TW101135493A patent/TW201326209A/zh unknown
- 2012-09-27 TW TW107101834A patent/TW201817744A/zh unknown
- 2012-09-27 TW TW107101835A patent/TW201817745A/zh unknown
- 2012-09-28 CN CN201280058760.7A patent/CN103958547B/zh not_active Expired - Fee Related
- 2012-09-28 EP EP23210057.8A patent/EP4324850A3/en active Pending
- 2012-09-28 CN CN201810780566.9A patent/CN108948197A/zh not_active Withdrawn
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- 2012-09-28 RU RU2018118993A patent/RU2018118993A/ru not_active Application Discontinuation
- 2012-09-28 KR KR1020147011698A patent/KR20140069332A/ko not_active Withdrawn
- 2012-09-28 SG SG10201808187TA patent/SG10201808187TA/en unknown
- 2012-09-28 RU RU2014117500/10A patent/RU2014117500A/ru unknown
- 2012-09-28 EP EP12775324.2A patent/EP2760890B1/en active Active
- 2012-09-28 WO PCT/JP2012/006218 patent/WO2013046704A2/en not_active Ceased
- 2012-09-28 US US14/347,187 patent/US10253100B2/en active Active
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- 2012-09-28 BR BR112014007290A patent/BR112014007290A2/pt active Search and Examination
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