KR20140069332A - 항원 제거를 촉진하는 에프씨알엔 결합 도메인을 갖는 치료학적 항원 결합 분자 - Google Patents
항원 제거를 촉진하는 에프씨알엔 결합 도메인을 갖는 치료학적 항원 결합 분자 Download PDFInfo
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- KR20140069332A KR20140069332A KR1020147011698A KR20147011698A KR20140069332A KR 20140069332 A KR20140069332 A KR 20140069332A KR 1020147011698 A KR1020147011698 A KR 1020147011698A KR 20147011698 A KR20147011698 A KR 20147011698A KR 20140069332 A KR20140069332 A KR 20140069332A
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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Cited By (7)
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| KR20180125036A (ko) * | 2015-09-18 | 2018-11-21 | 추가이 세이야쿠 가부시키가이샤 | Il-8에 결합하는 항체 및 그의 사용 |
| KR20200038562A (ko) * | 2016-08-05 | 2020-04-13 | 추가이 세이야쿠 가부시키가이샤 | Il-8 관련 질환의 치료용 또는 예방용 조성물 |
| US11454633B2 (en) | 2014-12-19 | 2022-09-27 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies, polypeptides containing variant Fc regions, and methods of use |
| US11891434B2 (en) | 2010-11-30 | 2024-02-06 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
| US12116414B2 (en) | 2007-09-26 | 2024-10-15 | Chugai Seiyaku Kabushiki Kaisha | Method of modifying isoelectric point of antibody via amino acid substitution in CDR |
| US12252532B2 (en) | 2015-12-25 | 2025-03-18 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
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| CA2721052C (en) | 2008-04-11 | 2023-02-21 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
| TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
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| WO2013002362A1 (ja) | 2011-06-30 | 2013-01-03 | 中外製薬株式会社 | ヘテロ二量化ポリペプチド |
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| KR102276528B1 (ko) * | 2011-09-30 | 2021-07-12 | 추가이 세이야쿠 가부시키가이샤 | 이온 농도 의존성 결합 분자 라이브러리 |
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| WO2013051294A1 (ja) | 2011-10-05 | 2013-04-11 | 中外製薬株式会社 | 糖鎖受容体結合ドメインを含む抗原の血漿中からの消失を促進する抗原結合分子 |
| CA2857159C (en) | 2011-11-30 | 2024-05-07 | Chugai Seiyaku Kabushiki Kaisha | Drug containing carrier into cell for forming immune complex |
| EP2813568B1 (en) | 2012-02-09 | 2025-04-23 | Chugai Seiyaku Kabushiki Kaisha | Modified fc region of antibody |
| KR20250007041A (ko) | 2012-02-24 | 2025-01-13 | 추가이 세이야쿠 가부시키가이샤 | ＦｃγＲＩＩＢ를 매개로 항원의 소실을 촉진하는 항원 결합 분자 |
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| EP2889377B1 (en) | 2012-08-24 | 2020-01-08 | Chugai Seiyaku Kabushiki Kaisha | Fcyriib-specific fc region variant |
| WO2014030750A1 (ja) | 2012-08-24 | 2014-02-27 | 中外製薬株式会社 | マウスFcγRII特異的Fc抗体 |
| TW201418707A (zh) | 2012-09-21 | 2014-05-16 | Alexion Pharma Inc | 補體組分ｃ５拮抗劑之篩選分析 |
| BR112015018438A2 (pt) | 2013-01-31 | 2017-07-18 | Seoul Nat Univ R&Db Foundation | anticorpo contra c5 e método para prevenir e tratar doenças relacionadas a complemento |
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| US9321686B2 (en) | 2013-03-15 | 2016-04-26 | Forta Corporation | Reinforcement fiber coating compositions, methods of making and treating, and uses for improved adhesion to asphalt and portland cement concrete |
| EP2982689B1 (en) | 2013-04-02 | 2020-08-26 | Chugai Seiyaku Kabushiki Kaisha | Fc region variant |
| NZ711451A (en) | 2014-03-07 | 2016-05-27 | Alexion Pharma Inc | Anti-c5 antibodies having improved pharmacokinetics |
| CN106459192B (zh) | 2014-06-30 | 2021-08-03 | 默克专利股份公司 | 具有pH依赖性抗原结合的抗TNFa抗体 |
| RS62749B1 (sr) * | 2014-12-19 | 2022-01-31 | Chugai Pharmaceutical Co Ltd | Anti-c5 antitela i načini njihove upotrebe |
| CA2974547A1 (en) * | 2015-02-05 | 2016-08-11 | Chugai Seiyaku Kabushiki Kaisha | Antibodies comprising an ion concentration dependent antigen-binding domain, fc region variants, il-8-binding antibodies, and uses thereof |
-
2012
- 2012-09-27 TW TW107101834A patent/TW201817744A/zh unknown
- 2012-09-27 TW TW107101835A patent/TW201817745A/zh unknown
- 2012-09-27 TW TW101135493A patent/TW201326209A/zh unknown
- 2012-09-28 CA CA2850035A patent/CA2850035A1/en not_active Abandoned
- 2012-09-28 KR KR1020147011698A patent/KR20140069332A/ko not_active Withdrawn
- 2012-09-28 SG SG10201808187TA patent/SG10201808187TA/en unknown
- 2012-09-28 JP JP2014514947A patent/JP6204350B2/ja active Active
- 2012-09-28 CN CN201810780566.9A patent/CN108948197A/zh not_active Withdrawn
- 2012-09-28 SG SG11201401098TA patent/SG11201401098TA/en unknown
- 2012-09-28 BR BR112014007290A patent/BR112014007290A2/pt active Search and Examination
- 2012-09-28 EP EP19150272.3A patent/EP3549956A3/en not_active Withdrawn
- 2012-09-28 WO PCT/JP2012/006218 patent/WO2013046704A2/en not_active Ceased
- 2012-09-28 MX MX2014003891A patent/MX2014003891A/es unknown
- 2012-09-28 EP EP12775324.2A patent/EP2760890B1/en active Active
- 2012-09-28 RU RU2018118993A patent/RU2018118993A/ru not_active Application Discontinuation
- 2012-09-28 AU AU2012313670A patent/AU2012313670B2/en not_active Ceased
- 2012-09-28 CN CN201280058760.7A patent/CN103958547B/zh not_active Expired - Fee Related
- 2012-09-28 US US14/347,187 patent/US10253100B2/en active Active
- 2012-09-28 RU RU2014117500/10A patent/RU2014117500A/ru unknown
- 2012-09-28 EP EP23210057.8A patent/EP4324850A3/en active Pending
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2017
- 2017-08-18 AU AU2017216587A patent/AU2017216587B2/en not_active Ceased
- 2017-08-31 JP JP2017166638A patent/JP6541730B2/ja active Active
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2019
- 2019-01-09 HK HK19100308.6A patent/HK1257946A1/zh unknown
- 2019-02-01 US US16/264,735 patent/US20190233525A1/en not_active Abandoned
- 2019-06-11 JP JP2019108321A patent/JP7001637B2/ja active Active
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2021
- 2021-12-24 JP JP2021211155A patent/JP2022034037A/ja active Pending
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2023
- 2023-12-08 US US18/533,360 patent/US20240117059A1/en active Pending
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2024
- 2024-04-26 JP JP2024072301A patent/JP2024097064A/ja active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12473375B2 (en) | 2006-03-31 | 2025-11-18 | Chugai Seiyaku Kabushiki Kaisha | Methods for controlling blood pharmacokinetics of antibodies |
| US12116414B2 (en) | 2007-09-26 | 2024-10-15 | Chugai Seiyaku Kabushiki Kaisha | Method of modifying isoelectric point of antibody via amino acid substitution in CDR |
| US12122840B2 (en) | 2007-09-26 | 2024-10-22 | Chugai Seiyaku Kabushiki Kaisha | Method of modifying isoelectric point of antibody via amino acid substitution in CDR |
| US11891434B2 (en) | 2010-11-30 | 2024-02-06 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
| US11454633B2 (en) | 2014-12-19 | 2022-09-27 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies, polypeptides containing variant Fc regions, and methods of use |
| US12169205B2 (en) | 2014-12-19 | 2024-12-17 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use |
| KR20180125036A (ko) * | 2015-09-18 | 2018-11-21 | 추가이 세이야쿠 가부시키가이샤 | Il-8에 결합하는 항체 및 그의 사용 |
| US12252532B2 (en) | 2015-12-25 | 2025-03-18 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
| KR20200038562A (ko) * | 2016-08-05 | 2020-04-13 | 추가이 세이야쿠 가부시키가이샤 | Il-8 관련 질환의 치료용 또는 예방용 조성물 |
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