DK1689777T3 - Fremgangsmåde til oprensning af il18-bindende protein - Google Patents

Fremgangsmåde til oprensning af il18-bindende protein

Info

Publication number
DK1689777T3
DK1689777T3 DK04798163T DK04798163T DK1689777T3 DK 1689777 T3 DK1689777 T3 DK 1689777T3 DK 04798163 T DK04798163 T DK 04798163T DK 04798163 T DK04798163 T DK 04798163T DK 1689777 T3 DK1689777 T3 DK 1689777T3
Authority
DK
Denmark
Prior art keywords
binding protein
purifying
purification
fluid
relates
Prior art date
Application number
DK04798163T
Other languages
English (en)
Inventor
Mara Rossi
Thierry Ziegler
Laure Valognes
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Application granted granted Critical
Publication of DK1689777T3 publication Critical patent/DK1689777T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK04798163T 2003-11-05 2004-11-04 Fremgangsmåde til oprensning af il18-bindende protein DK1689777T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51744703P 2003-11-05 2003-11-05
EP03104092 2003-11-05
PCT/EP2004/052807 WO2005049649A1 (en) 2003-11-05 2004-11-04 Process for the purification of il-18 binding protein

Publications (1)

Publication Number Publication Date
DK1689777T3 true DK1689777T3 (da) 2007-06-11

Family

ID=34924126

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04798163T DK1689777T3 (da) 2003-11-05 2004-11-04 Fremgangsmåde til oprensning af il18-bindende protein

Country Status (19)

Country Link
US (1) US7820800B2 (da)
EP (1) EP1689777B1 (da)
JP (1) JP4741504B2 (da)
AT (1) ATE360647T1 (da)
AU (1) AU2004291341B2 (da)
CA (1) CA2544146C (da)
CY (1) CY1106683T1 (da)
DE (1) DE602004006157T2 (da)
DK (1) DK1689777T3 (da)
ES (1) ES2285543T3 (da)
HR (1) HRP20070196T3 (da)
IL (1) IL175431A (da)
ME (1) ME01198B (da)
NO (1) NO330538B1 (da)
PL (1) PL1689777T3 (da)
PT (1) PT1689777E (da)
RS (1) RS50516B (da)
SI (1) SI1689777T1 (da)
WO (1) WO2005049649A1 (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004219917B2 (en) 2003-03-11 2008-01-31 Merck Serono Sa Expression vectors comprising the mCMV IE2 promoter
CA2524403C (en) * 2003-05-13 2013-07-09 Applied Research Systems Ars Holding N.V. Active variants of the il-18 binding protein and medical uses thereof
DE602004029598D1 (de) 2003-10-21 2010-11-25 Merck Serono Sa Minimale dna sequenz, die als chromatin-isolator wirkt, und deren verwendung für die protein-expression
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
WO2005083058A1 (en) 2004-03-01 2005-09-09 Ares Trading S.A. Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells
US7439336B2 (en) 2004-06-29 2008-10-21 Ares Trading S.A. Process for the purification of IL-18 binding protein
CA2604877A1 (en) * 2005-04-11 2006-10-19 J.P. Sercel Associates Inc. Protein purification
EP1885753B1 (en) * 2005-06-03 2011-07-27 Ares Trading S.A. Production of recombinant Il-18 binding protein
SI1891088T1 (sl) * 2005-06-10 2012-02-29 Ares Trading Sa Postopek za äśiĺ äśenje il-18 vezavnega proteina
BRPI0817294A2 (pt) 2007-09-26 2015-03-17 Chugai Pharmaceutical Co Ltd Método de modificação do ponto isoelétrico de anticorpo via substituição de aminoácido em cdr.
KR20100103595A (ko) 2008-01-18 2010-09-27 에프. 호프만-라 로슈 아게 비-글라이코실화된 단백질의 정제
MX2010011184A (es) * 2008-04-11 2011-01-20 Chugai Pharmaceutical Co Ltd Molecula de union de antigeno capaz de unir repetidamente a dos o mas moleculas de antigeno.
TWI440469B (zh) 2008-09-26 2014-06-11 Chugai Pharmaceutical Co Ltd Improved antibody molecules
WO2011156369A2 (en) * 2010-06-07 2011-12-15 Dr. Reddy's Laboratories Ltd. Purification of modified cytokines
CN108715614A (zh) 2010-11-30 2018-10-30 中外制药株式会社 与多分子的抗原重复结合的抗原结合分子
AU2012222252B2 (en) 2011-02-25 2016-08-25 Chugai Seiyaku Kabushiki Kaisha FcgammaRIIb-specific Fc antibody
BR112013024933A2 (pt) 2011-03-29 2016-09-06 Glaxosmithkline Llc sistema tampão para purificação de proteínas
US20150050269A1 (en) 2011-09-30 2015-02-19 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities
TW201326209A (zh) 2011-09-30 2013-07-01 Chugai Pharmaceutical Co Ltd 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子
RU2739792C1 (ru) 2011-11-30 2020-12-28 Чугаи Сейяку Кабусики Кайся Содержащий лекарственное средство переносчик в клетку для формирования иммунного комплекса
BR112015024587B1 (pt) 2013-04-02 2022-11-29 Chugai Seiyaku Kabushiki Kaisha Variante de região fc de igg1 humana, polipeptídeo compreendendo a mesma, seu método de produção e composição farmacêutica
CA2930350C (en) * 2014-03-10 2021-04-06 Richter Gedeon Nyrt. Immunoglobulin purification using pre-cleaning steps
CA2970732C (en) * 2014-12-15 2023-05-16 Merck Patent Gmbh Target molecule capture from crude solutions
KR101860280B1 (ko) 2014-12-19 2018-05-21 추가이 세이야쿠 가부시키가이샤 항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
ES2899894T3 (es) 2014-12-19 2022-03-15 Chugai Pharmaceutical Co Ltd Anticuerpos anti-C5 y métodos de uso
MX2017008978A (es) 2015-02-05 2017-10-25 Chugai Pharmaceutical Co Ltd Anticuerpos que comprenden un dominio de union al antigeno dependiente de la concentracion ionica, variantes de la region fc, antiocuerpor de union a interleucina 8 (il-8) y usos de los mismos.
KR101892883B1 (ko) 2015-02-27 2018-10-05 추가이 세이야쿠 가부시키가이샤 Il-6 관련 질환 치료용 조성물
JP7141336B2 (ja) 2015-12-25 2022-09-22 中外製薬株式会社 抗ミオスタチン抗体および使用方法
EP3494991A4 (en) 2016-08-05 2020-07-29 Chugai Seiyaku Kabushiki Kaisha COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATING TO IL-8
WO2018139623A1 (en) 2017-01-30 2018-08-02 Chugai Seiyaku Kabushiki Kaisha Anti-sclerostin antibodies and methods of use
EP3620531A4 (en) 2017-05-02 2021-03-17 National Center of Neurology and Psychiatry METHOD OF PREDICTION AND EVALUATION OF THERAPEUTIC EFFECT IN DISEASES RELATING TO IL-6 AND NEUTROPHILS

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
JP4216950B2 (ja) * 1998-09-01 2009-01-28 株式会社林原生物化学研究所 インターロイキン−１８結合蛋白質
WO2000012555A1 (fr) * 1998-09-01 2000-03-09 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Proteine de liaison de l'interleukine 18
US20020052475A1 (en) * 2000-07-20 2002-05-02 Schering Ag High affinity soluble interleukin-18 receptor
EA005769B1 (ru) * 2001-03-08 2005-06-30 Арес Трейдинг С.А. Мутанты интерлейкина-18, их продуцирование и применение
KR20040023630A (ko) * 2001-06-26 2004-03-18 아브게닉스, 인크. Ｏｐｇｌ에 결합하는 항체
DK1495055T3 (da) * 2002-04-18 2013-11-11 Genencor Int Produktion af funktionelle antistoffer i filamentøse svampe
AU2004219917B2 (en) 2003-03-11 2008-01-31 Merck Serono Sa Expression vectors comprising the mCMV IE2 promoter
CA2524403C (en) 2003-05-13 2013-07-09 Applied Research Systems Ars Holding N.V. Active variants of the il-18 binding protein and medical uses thereof
DE602004029598D1 (de) * 2003-10-21 2010-11-25 Merck Serono Sa Minimale dna sequenz, die als chromatin-isolator wirkt, und deren verwendung für die protein-expression
WO2005083058A1 (en) 2004-03-01 2005-09-09 Ares Trading S.A. Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells
US7439336B2 (en) * 2004-06-29 2008-10-21 Ares Trading S.A. Process for the purification of IL-18 binding protein
EP1885753B1 (en) 2005-06-03 2011-07-27 Ares Trading S.A. Production of recombinant Il-18 binding protein
SI1891088T1 (sl) 2005-06-10 2012-02-29 Ares Trading Sa Postopek za äśiĺ äśenje il-18 vezavnega proteina

Also Published As

Publication number Publication date
DE602004006157D1 (de) 2007-06-06
PL1689777T3 (pl) 2007-09-28
CA2544146C (en) 2012-10-02
IL175431A0 (en) 2006-09-05
US20070037734A1 (en) 2007-02-15
CA2544146A1 (en) 2005-06-02
US7820800B2 (en) 2010-10-26
EP1689777B1 (en) 2007-04-25
JP2007533651A (ja) 2007-11-22
EP1689777A1 (en) 2006-08-16
NO330538B1 (no) 2011-05-09
ME01198B (me) 2013-03-20
NO20062545L (no) 2006-08-03
SI1689777T1 (sl) 2007-08-31
ES2285543T3 (es) 2007-11-16
AU2004291341A1 (en) 2005-06-02
IL175431A (en) 2011-02-28
HRP20070196T3 (en) 2007-06-30
ATE360647T1 (de) 2007-05-15
WO2005049649A1 (en) 2005-06-02
DE602004006157T2 (de) 2008-01-03
PT1689777E (pt) 2007-05-31
AU2004291341B2 (en) 2010-08-05
CY1106683T1 (el) 2012-05-23
RS50516B (sr) 2010-05-07
JP4741504B2 (ja) 2011-08-03

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