SK284366B6 - Deriváty 6-(4-fenylbutoxy)hexylamínu, spôsob jeho prípravy a spôsob prípravy salmeterolu - Google Patents
Deriváty 6-(4-fenylbutoxy)hexylamínu, spôsob jeho prípravy a spôsob prípravy salmeterolu Download PDFInfo
- Publication number
- SK284366B6 SK284366B6 SK386-2001A SK3862001A SK284366B6 SK 284366 B6 SK284366 B6 SK 284366B6 SK 3862001 A SK3862001 A SK 3862001A SK 284366 B6 SK284366 B6 SK 284366B6
- Authority
- SK
- Slovakia
- Prior art keywords
- group
- formula
- compound
- benzyl
- process according
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/40—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the same carbon atom of the carbon skeleton, e.g. amino-ketals, ortho esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES009802014A ES2142771B1 (es) | 1998-09-28 | 1998-09-28 | Nuevos derivados de la 6-(4-fenil-butoxi) hexilamina y procedimiento para la obtencion de salmeterol. |
| PCT/ES1999/000294 WO2000018722A2 (es) | 1998-09-28 | 1999-09-20 | Nuevos derivados de la 6-(4-fenilbutoxi)hexilamina y procedimiento para la obtencion de salmeterol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK3862001A3 SK3862001A3 (en) | 2002-09-10 |
| SK284366B6 true SK284366B6 (sk) | 2005-02-04 |
Family
ID=8305274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK386-2001A SK284366B6 (sk) | 1998-09-28 | 1999-09-20 | Deriváty 6-(4-fenylbutoxy)hexylamínu, spôsob jeho prípravy a spôsob prípravy salmeterolu |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6388134B1 (ja) |
| EP (1) | EP1132373B1 (ja) |
| JP (1) | JP3786834B2 (ja) |
| KR (1) | KR100479256B1 (ja) |
| CN (1) | CN1189446C (ja) |
| AT (1) | ATE254596T1 (ja) |
| AU (1) | AU756042B2 (ja) |
| BR (1) | BR9913989A (ja) |
| CA (1) | CA2344647C (ja) |
| CZ (2) | CZ296902B6 (ja) |
| DE (1) | DE69912984D1 (ja) |
| EA (1) | EA003397B1 (ja) |
| ES (2) | ES2142771B1 (ja) |
| HU (1) | HUP0103969A3 (ja) |
| IL (1) | IL141991A (ja) |
| IS (1) | IS2016B (ja) |
| NO (2) | NO327780B1 (ja) |
| NZ (1) | NZ511157A (ja) |
| OA (1) | OA11660A (ja) |
| PL (1) | PL196116B1 (ja) |
| PT (1) | PT1132373E (ja) |
| SK (1) | SK284366B6 (ja) |
| TR (1) | TR200100862T2 (ja) |
| WO (1) | WO2000018722A2 (ja) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6835857B2 (en) | 2002-03-05 | 2004-12-28 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Process for the manufacture of 4-(6-bromohexyloxy)-butylbenzene |
| DE10209583B4 (de) * | 2002-03-05 | 2006-01-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung von 4-(6-Bromhexyloxy)-butylbenzol |
| AU2006303124B2 (en) | 2005-10-17 | 2013-03-28 | Generics [Uk] Limited | Novel process |
| ES2288114B1 (es) * | 2006-04-26 | 2008-12-01 | Quimica Sintetica S.A. | Nuevo procedimiento de sintesis de (6-(4-fenilbutoxi)hexil)aminas n-sustituidas y su uso en la sintesis de salmeterol xinafoato. |
| EP2127641A1 (en) | 2008-05-26 | 2009-12-02 | Inke, S.A. | Micronisable form of salmeterol xinafoate |
| CN101712622B (zh) * | 2009-11-10 | 2012-10-03 | 浙江万里学院 | 抗哮喘药物沙美特罗的制备方法 |
| CN103435505A (zh) * | 2013-09-05 | 2013-12-11 | 南京工业大学 | 一种合成(r)-沙美特罗的方法 |
| US9447067B2 (en) * | 2014-10-03 | 2016-09-20 | Amphastar Pahmaceuticals, Inc. | Method of preparing intermediate of salmeterol |
| KR20230001708U (ko) | 2022-02-17 | 2023-08-24 | 유기택 | 재접착식 슬림 평면형 액자 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZW6584A1 (en) * | 1983-04-18 | 1985-04-17 | Glaxo Group Ltd | Phenethanolamine derivatives |
| AU581887B2 (en) * | 1984-04-17 | 1989-03-09 | Glaxo Group Limited | Ethanolamine compounds |
| ES2065269B1 (es) * | 1993-05-11 | 1995-10-01 | S A L V A T Lab Sa | 6-(4-(fenilbutoxi) hexilaminometil-4-hidroxi-a1,a3-bencenodimetanol. procedimiento para la obtencion del mismo y nuevos intermedios utilizados en su preparacion. |
-
1998
- 1998-09-28 ES ES009802014A patent/ES2142771B1/es not_active Expired - Fee Related
-
1999
- 1999-09-20 CN CNB998114324A patent/CN1189446C/zh not_active Expired - Fee Related
- 1999-09-20 ES ES99969711T patent/ES2212672T3/es not_active Expired - Lifetime
- 1999-09-20 NZ NZ511157A patent/NZ511157A/xx not_active IP Right Cessation
- 1999-09-20 CZ CZ20033118A patent/CZ296902B6/cs not_active IP Right Cessation
- 1999-09-20 CZ CZ20010958A patent/CZ296901B6/cs not_active IP Right Cessation
- 1999-09-20 AT AT99969711T patent/ATE254596T1/de not_active IP Right Cessation
- 1999-09-20 HU HU0103969A patent/HUP0103969A3/hu unknown
- 1999-09-20 SK SK386-2001A patent/SK284366B6/sk not_active IP Right Cessation
- 1999-09-20 OA OA1200100079A patent/OA11660A/en unknown
- 1999-09-20 PT PT99969711T patent/PT1132373E/pt unknown
- 1999-09-20 EA EA200100391A patent/EA003397B1/ru not_active IP Right Cessation
- 1999-09-20 US US09/806,538 patent/US6388134B1/en not_active Expired - Lifetime
- 1999-09-20 AU AU59839/99A patent/AU756042B2/en not_active Ceased
- 1999-09-20 PL PL348572A patent/PL196116B1/pl not_active IP Right Cessation
- 1999-09-20 BR BR9913989-8A patent/BR9913989A/pt not_active Application Discontinuation
- 1999-09-20 CA CA002344647A patent/CA2344647C/en not_active Expired - Fee Related
- 1999-09-20 JP JP2000572184A patent/JP3786834B2/ja not_active Expired - Fee Related
- 1999-09-20 WO PCT/ES1999/000294 patent/WO2000018722A2/es active IP Right Grant
- 1999-09-20 KR KR10-2001-7003977A patent/KR100479256B1/ko not_active IP Right Cessation
- 1999-09-20 TR TR2001/00862T patent/TR200100862T2/xx unknown
- 1999-09-20 IL IL14199199A patent/IL141991A/en not_active IP Right Cessation
- 1999-09-20 DE DE69912984T patent/DE69912984D1/de not_active Expired - Lifetime
- 1999-09-20 EP EP99969711A patent/EP1132373B1/en not_active Expired - Lifetime
-
2001
- 2001-03-08 IS IS5880A patent/IS2016B/is unknown
- 2001-03-08 NO NO20011197A patent/NO327780B1/no not_active IP Right Cessation
-
2008
- 2008-10-16 NO NO20084343A patent/NO20084343L/no not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Dube et al. | Reductive N-alkylation of amides, carbamates and ureas | |
| US5225585A (en) | Production of fluoxetine and new intermediates | |
| US9035061B2 (en) | Process for preparing a biphenyl-2-ylcarbamic acid | |
| WO2009090320A1 (fr) | Procede de preparation d'une piperidine disubstituee et intermediaires | |
| KR20120006035A (ko) | 시토크롬 ｐ４５０ 모노옥시게나아제 억제제의 제조 방법 및 관련 중간체 | |
| SK284366B6 (sk) | Deriváty 6-(4-fenylbutoxy)hexylamínu, spôsob jeho prípravy a spôsob prípravy salmeterolu | |
| CZ284256B6 (cs) | Nový způsob výroby formoterolu a příbuzných sloučenin | |
| JP4299677B2 (ja) | コンブレタスタチンの製造方法 | |
| US5618968A (en) | N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation | |
| US20100137592A1 (en) | Process for preparing purine derivative | |
| EP2666771A1 (en) | Synthesis of Aminocyclopentanetriol Derivatives | |
| EP2072505A2 (en) | A process for the preparation of oxazolidinone derivatives | |
| FR2528422A1 (fr) | Nouveaux derives du 1,2,3,4-tetrahydronaphtalene, procede pour leur preparation et composition pharmaceutique contenant ces derives | |
| SK284168B6 (sk) | Alkoxyfuranónamínové deriváty, spôsob ich prípravy, ich použitie a medziprodukty na ich prípravu | |
| SK29099A3 (en) | Process for the preparation of fluoxetine | |
| JPS649993B2 (ja) | ||
| PL182914B1 (pl) | Sposób wytwarzania (-)-N-metylo-N-[4-(4-fenylo-4-acetyloaminopiperydyn-1-ylo)-2-(3,4-dichlorofenylo)butylo]benzamidu | |
| JP2002517488A (ja) | 大員環メタロプロテアーゼ阻害剤の製造法 | |
| CA2446605A1 (en) | Novel processes for the preparation of adenosine compounds and intermediates thereto | |
| MXPA01003222A (en) | New derivatives of 6-(4-phenylbutoxy)hexylamine and process for producing salmeterol | |
| JPH054949A (ja) | 光学活性シクロブチルアミン類の製造方法 | |
| SK4732000A3 (en) | Preparation of asymmetric cyclic ureas through a monoacylated diamine intermediate | |
| SK283454B6 (sk) | Spôsob výroby terbinafínu a medziprodukt jeho prípravy E-izomér tozylátovej soli (E)-N-(3-chlór-2-propenyl)-N-metyl- 1-naftalénmetylamínu |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed due to non-payment of maintenance fees |
Effective date: 20100920 |