SI9012429B - Novi derivati kromana in tiokromana - Google Patents
Novi derivati kromana in tiokromana Download PDFInfo
- Publication number
- SI9012429B SI9012429B SI9012429A SI9012429A SI9012429B SI 9012429 B SI9012429 B SI 9012429B SI 9012429 A SI9012429 A SI 9012429A SI 9012429 A SI9012429 A SI 9012429A SI 9012429 B SI9012429 B SI 9012429B
- Authority
- SI
- Slovenia
- Prior art keywords
- alkyl
- formula
- alkenyl
- compound
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Threshing Machine Elements (AREA)
- Liquid Crystal Substances (AREA)
- Bakery Products And Manufacturing Methods Therefor (AREA)
- Curing Cements, Concrete, And Artificial Stone (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
- Harvester Elements (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8904361A SE8904361D0 (sv) | 1989-12-22 | 1989-12-22 | New chroman and thiochroman derivatives |
| YU242990A YU47936B (sh) | 1989-12-22 | 1990-12-21 | Derivati hromana i tiohromana i postupak za njihovo dobijanje |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SI9012429A SI9012429A (en) | 1997-12-31 |
| SI9012429B true SI9012429B (sl) | 1998-10-31 |
Family
ID=20377869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9012429A SI9012429B (sl) | 1989-12-22 | 1990-12-21 | Novi derivati kromana in tiokromana |
Country Status (42)
| Country | Link |
|---|---|
| EP (1) | EP0460169B1 (lv) |
| JP (1) | JP2879972B2 (lv) |
| KR (1) | KR0178991B1 (lv) |
| CN (1) | CN1037438C (lv) |
| AT (1) | ATE138918T1 (lv) |
| AU (1) | AU641204B2 (lv) |
| CA (1) | CA2047237C (lv) |
| CY (1) | CY1991A (lv) |
| CZ (1) | CZ283630B6 (lv) |
| DE (1) | DE69027311T2 (lv) |
| DK (1) | DK0460169T3 (lv) |
| DZ (1) | DZ1469A1 (lv) |
| EG (1) | EG19749A (lv) |
| ES (1) | ES2087993T3 (lv) |
| FI (1) | FI102177B1 (lv) |
| GR (1) | GR3020497T3 (lv) |
| HK (1) | HK55897A (lv) |
| HR (1) | HRP920851B1 (lv) |
| HU (1) | HU211860A9 (lv) |
| ID (1) | ID945B (lv) |
| IE (1) | IE80753B1 (lv) |
| IL (1) | IL96712A (lv) |
| IS (1) | IS1665B (lv) |
| LT (1) | LT3967B (lv) |
| LV (2) | LV10449B (lv) |
| MX (1) | MX23889A (lv) |
| NO (1) | NO180336C (lv) |
| NZ (1) | NZ236407A (lv) |
| PH (1) | PH30797A (lv) |
| PL (3) | PL164609B1 (lv) |
| PT (1) | PT96304B (lv) |
| RU (1) | RU2092483C1 (lv) |
| SA (1) | SA90110186B1 (lv) |
| SE (1) | SE8904361D0 (lv) |
| SG (1) | SG48043A1 (lv) |
| SI (1) | SI9012429B (lv) |
| SK (1) | SK657890A3 (lv) |
| TW (1) | TW221056B (lv) |
| UA (1) | UA34416C2 (lv) |
| WO (1) | WO1991009853A1 (lv) |
| YU (2) | YU47936B (lv) |
| ZA (1) | ZA909708B (lv) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5420151A (en) * | 1989-12-22 | 1995-05-30 | Aktiebolaget Astra | Chroman derivatives |
| EP0471515B1 (en) * | 1990-08-15 | 1997-03-05 | Eli Lilly And Company | Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes, 3-aminochromanes and 3-aminothiochromanes |
| ZA92767B (en) * | 1991-02-08 | 1993-08-03 | Lilly Co Eli | Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes. |
| HRP920935A2 (en) * | 1991-10-08 | 1995-08-31 | Astra Ab | New therapeutically active compound |
| SE9103745D0 (sv) * | 1991-12-18 | 1991-12-18 | Wikstroem Haakan | Aryl-triflates and related compounds |
| FR2691149B1 (fr) * | 1992-05-18 | 1994-07-08 | Adir | Nouveaux composes thiochromaniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5434174A (en) * | 1992-07-17 | 1995-07-18 | Eli Lilly And Company | Isoxazole derivatives for the treatment of irritable bowel syndrome |
| SE9301732D0 (sv) * | 1993-05-18 | 1993-05-18 | Haakan Wilhelm Wikstroem | New centrally acting 5-,6-,7-, and 8-substituted sulphone esters of n-monosubstituted 2-aminotetralins |
| SE9703377D0 (sv) * | 1997-09-18 | 1997-09-18 | Astra Ab | New compounds |
| SE9703378D0 (sv) | 1997-09-18 | 1997-09-18 | Astra Ab | New compounds |
| US6184226B1 (en) | 1998-08-28 | 2001-02-06 | Scios Inc. | Quinazoline derivatives as inhibitors of P-38 α |
| EP1353914A2 (en) | 2001-01-16 | 2003-10-22 | AstraZeneca AB | Therapeutic chromone compounds |
| WO2002055012A2 (en) | 2001-01-16 | 2002-07-18 | Astrazeneca Ab | Therapeutic heterocyclic compounds |
| JP4280068B2 (ja) * | 2001-01-16 | 2009-06-17 | アストラゼネカ・アクチエボラーグ | 治療用クロマン化合物 |
| DK1408976T5 (da) | 2001-07-20 | 2011-01-10 | Psychogenics Inc | Behandling af ADHD (Attention deficit hyperactivity disorder) |
| US7125904B2 (en) | 2002-10-11 | 2006-10-24 | Portela & C.A., S.A. | Peripherally-selective inhibitors of dopamine-β-hydroxylase and method of their preparation |
| SE0301796D0 (sv) * | 2003-06-19 | 2003-06-19 | Astrazeneca Ab | New use II |
| SE0301795D0 (sv) * | 2003-06-19 | 2003-06-19 | Astrazeneca Ab | New use I |
| WO2008080120A2 (en) * | 2006-12-22 | 2008-07-03 | Wyeth | 3-amino chromane derivatives |
| SA08290245B1 (ar) * | 2007-04-23 | 2012-02-12 | استرازينيكا ايه بي | مشتقات كربو كساميد جديدة من -n (8-اريل رباعي هيدرو نفثالين غير متجانس- 2- يل) أو -n (5-اريل كرومان غير متجانس -3-يل) لعلاج الألم |
| CN101712672B (zh) * | 2008-10-06 | 2013-02-06 | 中国中医科学院中药研究所 | 一种治疗心脑血管系统疾病新化合物及其制备方法、用途 |
| DE102010041948A1 (de) | 2010-10-04 | 2012-04-05 | Mahle International Gmbh | Filtereinrichtung |
| GB201316410D0 (en) | 2013-09-13 | 2013-10-30 | Bial Portela & Ca Sa | Processes for preparing peripherally-selective inhibitors of dopamine-?-hydroxylase and intermediates for use therein |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3679378D1 (de) * | 1985-09-03 | 1991-06-27 | Ciba Geigy Ag | 3-amino-dihydro-(1)-benzopyrane und benzothiopyrane. |
| US4801605A (en) * | 1986-08-29 | 1989-01-31 | Ciba-Geigy Corporation | 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans |
| SE8605504D0 (sv) * | 1986-12-19 | 1986-12-19 | Astra Laekemedel Ab | Novel chroman derivatives |
| US5258287A (en) * | 1988-03-22 | 1993-11-02 | Genentech, Inc. | DNA encoding and methods of production of insulin-like growth factor binding protein BP53 |
-
1989
- 1989-12-22 SE SE8904361A patent/SE8904361D0/xx unknown
-
1990
- 1990-12-03 ZA ZA909708A patent/ZA909708B/xx unknown
- 1990-12-10 NZ NZ236407A patent/NZ236407A/xx unknown
- 1990-12-11 PH PH41705A patent/PH30797A/en unknown
- 1990-12-12 DZ DZ900224A patent/DZ1469A1/fr active
- 1990-12-17 IE IE453590A patent/IE80753B1/en not_active IP Right Cessation
- 1990-12-18 IL IL9671290A patent/IL96712A/en not_active IP Right Cessation
- 1990-12-19 JP JP3501912A patent/JP2879972B2/ja not_active Expired - Fee Related
- 1990-12-19 IS IS3662A patent/IS1665B/is unknown
- 1990-12-19 AU AU69770/91A patent/AU641204B2/en not_active Ceased
- 1990-12-19 WO PCT/SE1990/000863 patent/WO1991009853A1/en active IP Right Grant
- 1990-12-19 CA CA002047237A patent/CA2047237C/en not_active Expired - Fee Related
- 1990-12-19 RU SU905001901A patent/RU2092483C1/ru not_active IP Right Cessation
- 1990-12-19 EP EP91901496A patent/EP0460169B1/en not_active Expired - Lifetime
- 1990-12-19 AT AT91901496T patent/ATE138918T1/de not_active IP Right Cessation
- 1990-12-19 UA UA5001901A patent/UA34416C2/uk unknown
- 1990-12-19 KR KR1019910700957A patent/KR0178991B1/ko not_active IP Right Cessation
- 1990-12-19 SG SG1996006565A patent/SG48043A1/en unknown
- 1990-12-19 DE DE69027311T patent/DE69027311T2/de not_active Expired - Fee Related
- 1990-12-19 ES ES91901496T patent/ES2087993T3/es not_active Expired - Lifetime
- 1990-12-19 DK DK91901496.9T patent/DK0460169T3/da active
- 1990-12-20 PT PT96304A patent/PT96304B/pt not_active IP Right Cessation
- 1990-12-20 EG EG75290A patent/EG19749A/xx active
- 1990-12-21 YU YU242990A patent/YU47936B/sh unknown
- 1990-12-21 PL PL90293066A patent/PL164609B1/pl not_active IP Right Cessation
- 1990-12-21 PL PL90288405A patent/PL164592B1/pl not_active IP Right Cessation
- 1990-12-21 SI SI9012429A patent/SI9012429B/sl not_active IP Right Cessation
- 1990-12-21 CZ CS906578A patent/CZ283630B6/cs not_active IP Right Cessation
- 1990-12-21 TW TW079110767A patent/TW221056B/zh active
- 1990-12-21 PL PL90293065A patent/PL164608B1/pl not_active IP Right Cessation
- 1990-12-21 SK SK6578-90A patent/SK657890A3/sk unknown
- 1990-12-21 CN CN90106068A patent/CN1037438C/zh not_active Expired - Fee Related
- 1990-12-21 MX MX2388990A patent/MX23889A/es unknown
- 1990-12-22 SA SA90110186A patent/SA90110186B1/ar unknown
-
1991
- 1991-04-22 YU YU72191A patent/YU47923B/sh unknown
- 1991-08-21 FI FI913943A patent/FI102177B1/fi not_active IP Right Cessation
- 1991-08-21 NO NO913273A patent/NO180336C/no unknown
-
1992
- 1992-01-30 ID IDP185892A patent/ID945B/id unknown
- 1992-10-02 HR HRP-2429/90A patent/HRP920851B1/xx not_active IP Right Cessation
-
1993
- 1993-06-30 LV LVP-93-819A patent/LV10449B/en unknown
- 1993-12-30 LT LTIP1730A patent/LT3967B/lt not_active IP Right Cessation
-
1995
- 1995-06-30 HU HU95P/P00717P patent/HU211860A9/hu unknown
-
1996
- 1996-07-10 GR GR960401865T patent/GR3020497T3/el unknown
-
1997
- 1997-05-01 HK HK55897A patent/HK55897A/xx not_active IP Right Cessation
- 1997-06-05 LV LVP-97-111A patent/LV11894B/lv unknown
- 1997-09-05 CY CY199197A patent/CY1991A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| IF | Valid on the event date | ||
| KO00 | Lapse of patent |
Effective date: 20070821 |