NO913273L - Nye kroman- og tiokromanderivater. - Google Patents

Nye kroman- og tiokromanderivater.

Info

Publication number
NO913273L
NO913273L NO91913273A NO913273A NO913273L NO 913273 L NO913273 L NO 913273L NO 91913273 A NO91913273 A NO 91913273A NO 913273 A NO913273 A NO 913273A NO 913273 L NO913273 L NO 913273L
Authority
NO
Norway
Prior art keywords
tiochroman
derivatives
new chroman
chroman
new
Prior art date
Application number
NO91913273A
Other languages
English (en)
Other versions
NO180336B (no
NO913273D0 (no
NO180336C (no
Inventor
Lars-Gunnar Larson
Rolf Noreen
Lucy Anna Renyi
Svante Bertil Ross
Daniel Dungan Sohn
Bjoern Eric Svensson
Seth Olov
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO913273D0 publication Critical patent/NO913273D0/no
Publication of NO913273L publication Critical patent/NO913273L/no
Publication of NO180336B publication Critical patent/NO180336B/no
Publication of NO180336C publication Critical patent/NO180336C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Liquid Crystal Substances (AREA)
  • Threshing Machine Elements (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Harvester Elements (AREA)
  • Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Medicinal Preparation (AREA)
NO913273A 1989-12-22 1991-08-21 Analogifremgangsmåte for fremstilling av nye, terapeutisk aktive kroman- og tiokromanderivater samt deres mellomprodukter NO180336C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8904361A SE8904361D0 (sv) 1989-12-22 1989-12-22 New chroman and thiochroman derivatives
PCT/SE1990/000863 WO1991009853A1 (en) 1989-12-22 1990-12-19 New chroman and thiochroman derivatives

Publications (4)

Publication Number Publication Date
NO913273D0 NO913273D0 (no) 1991-08-21
NO913273L true NO913273L (no) 1991-10-08
NO180336B NO180336B (no) 1996-12-23
NO180336C NO180336C (no) 1997-04-02

Family

ID=20377869

Family Applications (1)

Application Number Title Priority Date Filing Date
NO913273A NO180336C (no) 1989-12-22 1991-08-21 Analogifremgangsmåte for fremstilling av nye, terapeutisk aktive kroman- og tiokromanderivater samt deres mellomprodukter

Country Status (42)

Country Link
EP (1) EP0460169B1 (no)
JP (1) JP2879972B2 (no)
KR (1) KR0178991B1 (no)
CN (1) CN1037438C (no)
AT (1) ATE138918T1 (no)
AU (1) AU641204B2 (no)
CA (1) CA2047237C (no)
CY (1) CY1991A (no)
CZ (1) CZ283630B6 (no)
DE (1) DE69027311T2 (no)
DK (1) DK0460169T3 (no)
DZ (1) DZ1469A1 (no)
EG (1) EG19749A (no)
ES (1) ES2087993T3 (no)
FI (1) FI102177B (no)
GR (1) GR3020497T3 (no)
HK (1) HK55897A (no)
HR (1) HRP920851B1 (no)
HU (1) HU211860A9 (no)
ID (1) ID945B (no)
IE (1) IE80753B1 (no)
IL (1) IL96712A (no)
IS (1) IS1665B (no)
LT (1) LT3967B (no)
LV (2) LV10449B (no)
MX (1) MX23889A (no)
NO (1) NO180336C (no)
NZ (1) NZ236407A (no)
PH (1) PH30797A (no)
PL (3) PL164608B1 (no)
PT (1) PT96304B (no)
RU (1) RU2092483C1 (no)
SA (1) SA90110186B1 (no)
SE (1) SE8904361D0 (no)
SG (1) SG48043A1 (no)
SI (1) SI9012429B (no)
SK (1) SK657890A3 (no)
TW (1) TW221056B (no)
UA (1) UA34416C2 (no)
WO (1) WO1991009853A1 (no)
YU (2) YU47936B (no)
ZA (1) ZA909708B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
DE69124868T2 (de) * 1990-08-15 1997-07-10 Lilly Co Eli Ring-substituierte 2-Amino-1,2,3,4-tetra-hydronaphthaline, 3-Aminochromane und 3-Aminothiochromane
ZA92767B (en) * 1991-02-08 1993-08-03 Lilly Co Eli Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes.
HRP920935A2 (en) * 1991-10-08 1995-08-31 Astra Ab New therapeutically active compound
SE9103745D0 (sv) * 1991-12-18 1991-12-18 Wikstroem Haakan Aryl-triflates and related compounds
FR2691149B1 (fr) * 1992-05-18 1994-07-08 Adir Nouveaux composes thiochromaniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5434174A (en) * 1992-07-17 1995-07-18 Eli Lilly And Company Isoxazole derivatives for the treatment of irritable bowel syndrome
SE9301732D0 (sv) * 1993-05-18 1993-05-18 Haakan Wilhelm Wikstroem New centrally acting 5-,6-,7-, and 8-substituted sulphone esters of n-monosubstituted 2-aminotetralins
SE9703377D0 (sv) 1997-09-18 1997-09-18 Astra Ab New compounds
SE9703378D0 (sv) * 1997-09-18 1997-09-18 Astra Ab New compounds
US6184226B1 (en) 1998-08-28 2001-02-06 Scios Inc. Quinazoline derivatives as inhibitors of P-38 α
CN100509794C (zh) 2001-01-16 2009-07-08 阿斯特拉曾尼卡有限公司 治疗性杂环化合物
CN100384833C (zh) * 2001-01-16 2008-04-30 阿斯特拉曾尼卡有限公司 治疗用苯并二氢吡喃化合物
CA2433950A1 (en) 2001-01-16 2002-07-18 Timothy Davenport Therapeutic chromone compounds
DE60231507D1 (de) 2001-07-20 2010-07-01 Psychogenics Inc Behandlung von hyperaktivitätsstörungen und aufmerksamkeitsdefiziten
US7125904B2 (en) 2002-10-11 2006-10-24 Portela & C.A., S.A. Peripherally-selective inhibitors of dopamine-β-hydroxylase and method of their preparation
SE0301795D0 (sv) * 2003-06-19 2003-06-19 Astrazeneca Ab New use I
SE0301796D0 (sv) * 2003-06-19 2003-06-19 Astrazeneca Ab New use II
WO2008080120A2 (en) * 2006-12-22 2008-07-03 Wyeth 3-amino chromane derivatives
SA08290245B1 (ar) * 2007-04-23 2012-02-12 استرازينيكا ايه بي مشتقات كربو كساميد جديدة من -n (8-اريل رباعي هيدرو نفثالين غير متجانس- 2- يل) أو -n (5-اريل كرومان غير متجانس -3-يل) لعلاج الألم
CN101712672B (zh) * 2008-10-06 2013-02-06 中国中医科学院中药研究所 一种治疗心脑血管系统疾病新化合物及其制备方法、用途
DE102010041948A1 (de) 2010-10-04 2012-04-05 Mahle International Gmbh Filtereinrichtung
GB201316410D0 (en) 2013-09-13 2013-10-30 Bial Portela & Ca Sa Processes for preparing peripherally-selective inhibitors of dopamine-?-hydroxylase and intermediates for use therein

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0222996B1 (de) * 1985-09-03 1991-05-22 Ciba-Geigy Ag 3-Amino-dihydro-[1]-benzopyrane und Benzothiopyrane
US4801605A (en) * 1986-08-29 1989-01-31 Ciba-Geigy Corporation 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans
SE8605504D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel chroman derivatives
US5258287A (en) * 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53

Also Published As

Publication number Publication date
KR0178991B1 (ko) 1999-03-20
PL293066A1 (en) 1992-08-10
YU242990A (sh) 1993-10-20
FI102177B1 (fi) 1998-10-30
MX23889A (es) 1993-10-01
EG19749A (en) 1996-01-31
YU72191A (sh) 1995-01-31
LTIP1730A (en) 1995-08-25
SI9012429A (en) 1997-12-31
KR920701193A (ko) 1992-08-11
DZ1469A1 (fr) 2004-09-13
PT96304B (pt) 1998-09-30
CN1037438C (zh) 1998-02-18
SG48043A1 (en) 1998-04-17
FI102177B (fi) 1998-10-30
NO180336B (no) 1996-12-23
DK0460169T3 (da) 1996-09-23
WO1991009853A1 (en) 1991-07-11
HK55897A (en) 1997-05-09
EP0460169A1 (en) 1991-12-11
SK280261B6 (sk) 1999-10-08
NO913273D0 (no) 1991-08-21
DE69027311D1 (en) 1996-07-11
IS1665B (is) 1997-07-04
ATE138918T1 (de) 1996-06-15
LV11894B (en) 1998-05-20
NO180336C (no) 1997-04-02
PL164608B1 (pl) 1994-08-31
CY1991A (en) 1997-09-05
IL96712A (en) 1995-08-31
LV11894A (lv) 1997-12-20
YU47936B (sh) 1996-05-20
CA2047237A1 (en) 1991-06-23
TW221056B (no) 1994-02-11
DE69027311T2 (de) 1996-10-24
ID945B (id) 1996-09-20
IE904535A1 (en) 1991-07-03
LT3967B (en) 1996-05-27
IL96712A0 (en) 1991-09-16
JPH04503682A (ja) 1992-07-02
PL164592B1 (pl) 1994-08-31
SE8904361D0 (sv) 1989-12-22
CN1052669A (zh) 1991-07-03
PT96304A (pt) 1991-09-30
CA2047237C (en) 2003-02-11
HU211860A9 (en) 1995-12-28
PL293065A1 (en) 1992-08-10
YU47923B (sh) 1996-05-20
EP0460169B1 (en) 1996-06-05
CZ657890A3 (cs) 1998-02-18
UA34416C2 (uk) 2001-03-15
AU6977091A (en) 1991-07-24
ZA909708B (en) 1991-08-28
LV10449B (en) 1995-10-20
SK657890A3 (en) 1999-10-08
HRP920851A2 (en) 1995-10-31
ES2087993T3 (es) 1996-08-01
SA90110186B1 (ar) 2001-11-11
AU641204B2 (en) 1993-09-16
CZ283630B6 (cs) 1998-05-13
IE80753B1 (en) 1999-01-13
IS3662A7 (is) 1991-06-23
GR3020497T3 (en) 1996-10-31
FI913943A0 (fi) 1991-08-21
PL164609B1 (en) 1994-08-31
HRP920851B1 (en) 2000-02-29
JP2879972B2 (ja) 1999-04-05
LV10449A (lv) 1995-02-20
SI9012429B (sl) 1998-10-31
PH30797A (en) 1997-10-17
RU2092483C1 (ru) 1997-10-10
NZ236407A (en) 1993-08-26

Similar Documents

Publication Publication Date Title
DK0460169T3 (da) Nye chroman- og thiochromanderivater
IL94278A0 (en) 2-saccharine derivatives,their preparation and pharmaceutical compositions containing them
ATE33638T1 (de) 2-amino-3-ethoxycarbonylamino-6-(p-fluorbenzylamino)-pyridingluconat und pharmazeutische zubereitungen, die diese substanz enthalten.
IL88971A (en) Disubstituted pyridines, process and intermediates, their preparation and pharmaceutical compositions containing them
DE69804766D1 (de) Isoflavonderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DK0486586T3 (da) Kynurensyrederivater, fremstilling deraf og farmaceutiske præparater, der indeholder dem
SE8900685D0 (sv) New compounds
JO1715B1 (en) Kroman derivatives and modern thiocroman