EG19749A - Process for preparing of new chroman and thiochroman derivatives - Google Patents

Process for preparing of new chroman and thiochroman derivatives

Info

Publication number
EG19749A
EG19749A EG75290A EG75290A EG19749A EG 19749 A EG19749 A EG 19749A EG 75290 A EG75290 A EG 75290A EG 75290 A EG75290 A EG 75290A EG 19749 A EG19749 A EG 19749A
Authority
EG
Egypt
Prior art keywords
preparing
thiochroman derivatives
new chroman
chroman
new
Prior art date
Application number
EG75290A
Other languages
English (en)
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Application granted granted Critical
Publication of EG19749A publication Critical patent/EG19749A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Threshing Machine Elements (AREA)
  • Liquid Crystal Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Medicinal Preparation (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Harvester Elements (AREA)
  • Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
EG75290A 1989-12-22 1990-12-20 Process for preparing of new chroman and thiochroman derivatives EG19749A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8904361A SE8904361D0 (sv) 1989-12-22 1989-12-22 New chroman and thiochroman derivatives

Publications (1)

Publication Number Publication Date
EG19749A true EG19749A (en) 1996-01-31

Family

ID=20377869

Family Applications (1)

Application Number Title Priority Date Filing Date
EG75290A EG19749A (en) 1989-12-22 1990-12-20 Process for preparing of new chroman and thiochroman derivatives

Country Status (42)

Country Link
EP (1) EP0460169B1 (lv)
JP (1) JP2879972B2 (lv)
KR (1) KR0178991B1 (lv)
CN (1) CN1037438C (lv)
AT (1) ATE138918T1 (lv)
AU (1) AU641204B2 (lv)
CA (1) CA2047237C (lv)
CY (1) CY1991A (lv)
CZ (1) CZ283630B6 (lv)
DE (1) DE69027311T2 (lv)
DK (1) DK0460169T3 (lv)
DZ (1) DZ1469A1 (lv)
EG (1) EG19749A (lv)
ES (1) ES2087993T3 (lv)
FI (1) FI102177B1 (lv)
GR (1) GR3020497T3 (lv)
HK (1) HK55897A (lv)
HR (1) HRP920851B1 (lv)
HU (1) HU211860A9 (lv)
ID (1) ID945B (lv)
IE (1) IE80753B1 (lv)
IL (1) IL96712A (lv)
IS (1) IS1665B (lv)
LT (1) LT3967B (lv)
LV (2) LV10449B (lv)
MX (1) MX23889A (lv)
NO (1) NO180336C (lv)
NZ (1) NZ236407A (lv)
PH (1) PH30797A (lv)
PL (3) PL164592B1 (lv)
PT (1) PT96304B (lv)
RU (1) RU2092483C1 (lv)
SA (1) SA90110186B1 (lv)
SE (1) SE8904361D0 (lv)
SG (1) SG48043A1 (lv)
SI (1) SI9012429B (lv)
SK (1) SK280261B6 (lv)
TW (1) TW221056B (lv)
UA (1) UA34416C2 (lv)
WO (1) WO1991009853A1 (lv)
YU (2) YU47936B (lv)
ZA (1) ZA909708B (lv)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
DE69124868T2 (de) * 1990-08-15 1997-07-10 Lilly Co Eli Ring-substituierte 2-Amino-1,2,3,4-tetra-hydronaphthaline, 3-Aminochromane und 3-Aminothiochromane
PT712837E (pt) * 1991-02-08 2001-03-30 Lilly Co Eli 2-amino-1,2,3,4-tetra-hidronaftalenos de 3-aminocromanos de anel substituido
HRP920935A2 (en) * 1991-10-08 1995-08-31 Astra Ab New therapeutically active compound
SE9103745D0 (sv) * 1991-12-18 1991-12-18 Wikstroem Haakan Aryl-triflates and related compounds
FR2691149B1 (fr) * 1992-05-18 1994-07-08 Adir Nouveaux composes thiochromaniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5434174A (en) * 1992-07-17 1995-07-18 Eli Lilly And Company Isoxazole derivatives for the treatment of irritable bowel syndrome
SE9301732D0 (sv) * 1993-05-18 1993-05-18 Haakan Wilhelm Wikstroem New centrally acting 5-,6-,7-, and 8-substituted sulphone esters of n-monosubstituted 2-aminotetralins
SE9703377D0 (sv) 1997-09-18 1997-09-18 Astra Ab New compounds
SE9703378D0 (sv) * 1997-09-18 1997-09-18 Astra Ab New compounds
US6184226B1 (en) 1998-08-28 2001-02-06 Scios Inc. Quinazoline derivatives as inhibitors of P-38 α
JP4280068B2 (ja) * 2001-01-16 2009-06-17 アストラゼネカ・アクチエボラーグ 治療用クロマン化合物
CN1592745A (zh) 2001-01-16 2005-03-09 阿斯特拉曾尼卡有限公司 治疗用苯并－γ－吡喃酮化合物
KR100864356B1 (ko) 2001-01-16 2008-10-17 아스트라제네카 아베 치료용 헤테로시클릭 화합물
US7504395B2 (en) 2001-07-20 2009-03-17 Psychogenics, Inc. Treatment for attention-deficit hyperactivity disorder
US7125904B2 (en) 2002-10-11 2006-10-24 Portela & C.A., S.A. Peripherally-selective inhibitors of dopamine-β-hydroxylase and method of their preparation
SE0301796D0 (sv) * 2003-06-19 2003-06-19 Astrazeneca Ab New use II
SE0301795D0 (sv) * 2003-06-19 2003-06-19 Astrazeneca Ab New use I
US20080221193A1 (en) * 2006-12-22 2008-09-11 Wyeth 3-amino chromane derivatives
SA08290245B1 (ar) * 2007-04-23 2012-02-12 استرازينيكا ايه بي مشتقات كربو كساميد جديدة من -n (8-اريل رباعي هيدرو نفثالين غير متجانس- 2- يل) أو -n (5-اريل كرومان غير متجانس -3-يل) لعلاج الألم
CN101712672B (zh) * 2008-10-06 2013-02-06 中国中医科学院中药研究所 一种治疗心脑血管系统疾病新化合物及其制备方法、用途
DE102010041948A1 (de) 2010-10-04 2012-04-05 Mahle International Gmbh Filtereinrichtung
GB201316410D0 (en) 2013-09-13 2013-10-30 Bial Portela & Ca Sa Processes for preparing peripherally-selective inhibitors of dopamine-?-hydroxylase and intermediates for use therein

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3679378D1 (de) * 1985-09-03 1991-06-27 Ciba Geigy Ag 3-amino-dihydro-(1)-benzopyrane und benzothiopyrane.
US4801605A (en) * 1986-08-29 1989-01-31 Ciba-Geigy Corporation 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans
SE8605504D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel chroman derivatives
US5258287A (en) * 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53

Also Published As

Publication number Publication date
FI913943A0 (fi) 1991-08-21
NZ236407A (en) 1993-08-26
SI9012429A (en) 1997-12-31
CN1052669A (zh) 1991-07-03
NO913273D0 (no) 1991-08-21
NO180336B (no) 1996-12-23
DE69027311T2 (de) 1996-10-24
LV10449A (lv) 1995-02-20
UA34416C2 (uk) 2001-03-15
IL96712A (en) 1995-08-31
ID945B (id) 1996-09-20
KR0178991B1 (ko) 1999-03-20
DZ1469A1 (fr) 2004-09-13
LV11894A (lv) 1997-12-20
ES2087993T3 (es) 1996-08-01
IE80753B1 (en) 1999-01-13
LT3967B (en) 1996-05-27
IL96712A0 (en) 1991-09-16
YU47923B (sh) 1996-05-20
PL293066A1 (en) 1992-08-10
ZA909708B (en) 1991-08-28
CZ657890A3 (cs) 1998-02-18
IS3662A7 (is) 1991-06-23
CY1991A (en) 1997-09-05
IS1665B (is) 1997-07-04
MX23889A (es) 1993-10-01
SA90110186B1 (ar) 2001-11-11
HK55897A (en) 1997-05-09
DK0460169T3 (da) 1996-09-23
SE8904361D0 (sv) 1989-12-22
FI102177B (fi) 1998-10-30
RU2092483C1 (ru) 1997-10-10
SI9012429B (sl) 1998-10-31
PH30797A (en) 1997-10-17
PL293065A1 (en) 1992-08-10
YU242990A (sh) 1993-10-20
CA2047237A1 (en) 1991-06-23
SK657890A3 (en) 1999-10-08
EP0460169B1 (en) 1996-06-05
PL164609B1 (en) 1994-08-31
EP0460169A1 (en) 1991-12-11
SG48043A1 (en) 1998-04-17
SK280261B6 (sk) 1999-10-08
HRP920851B1 (en) 2000-02-29
GR3020497T3 (en) 1996-10-31
PL164608B1 (pl) 1994-08-31
CZ283630B6 (cs) 1998-05-13
JP2879972B2 (ja) 1999-04-05
NO180336C (no) 1997-04-02
JPH04503682A (ja) 1992-07-02
TW221056B (lv) 1994-02-11
WO1991009853A1 (en) 1991-07-11
HRP920851A2 (en) 1995-10-31
YU72191A (sh) 1995-01-31
PT96304B (pt) 1998-09-30
PT96304A (pt) 1991-09-30
AU641204B2 (en) 1993-09-16
NO913273L (no) 1991-10-08
LV11894B (lv) 1998-05-20
LV10449B (en) 1995-10-20
HU211860A9 (en) 1995-12-28
FI102177B1 (fi) 1998-10-30
YU47936B (sh) 1996-05-20
IE904535A1 (en) 1991-07-03
CN1037438C (zh) 1998-02-18
AU6977091A (en) 1991-07-24
ATE138918T1 (de) 1996-06-15
PL164592B1 (pl) 1994-08-31
KR920701193A (ko) 1992-08-11
DE69027311D1 (en) 1996-07-11
LTIP1730A (en) 1995-08-25
CA2047237C (en) 2003-02-11

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