HU229997B1
(en)
*
|
2000-07-21 |
2015-04-28 |
Dendreon Corp San Diego |
Peptides as ns3-serine protease inhibitors of hepatitis c virus
|
CA2434386C
(en)
|
2001-01-22 |
2006-12-05 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
|
US6867185B2
(en)
*
|
2001-12-20 |
2005-03-15 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus
|
US7119072B2
(en)
|
2002-01-30 |
2006-10-10 |
Boehringer Ingelheim (Canada) Ltd. |
Macrocyclic peptides active against the hepatitis C virus
|
CA2369711A1
(en)
*
|
2002-01-30 |
2003-07-30 |
Boehringer Ingelheim (Canada) Ltd. |
Macrocyclic peptides active against the hepatitis c virus
|
US7091184B2
(en)
|
2002-02-01 |
2006-08-15 |
Boehringer Ingelheim International Gmbh |
Hepatitis C inhibitor tri-peptides
|
CA2369970A1
(en)
*
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
US6642204B2
(en)
|
2002-02-01 |
2003-11-04 |
Boehringer Ingelheim International Gmbh |
Hepatitis C inhibitor tri-peptides
|
US6828301B2
(en)
|
2002-02-07 |
2004-12-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
AU2003223602B8
(en)
|
2002-04-11 |
2010-05-27 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hepatitis C virus NS3-NS4 protease
|
PL213029B1
(pl)
*
|
2002-05-20 |
2012-12-31 |
Bristol Myers Squibb Co |
Podstawiona pochodna cykloalkilowa, zawierajaca ja kompozycja oraz ich zastosowanie
|
ES2350201T3
(es)
|
2002-05-20 |
2011-01-20 |
Bristol-Myers Squibb Company |
Sulfamidas heterocíclicas como inhibidores del virus de la hepatitis c.
|
ATE503764T1
(de)
|
2002-05-20 |
2011-04-15 |
Bristol Myers Squibb Co |
Inhibitoren des hepatitis-c-virus
|
MY140680A
(en)
|
2002-05-20 |
2010-01-15 |
Bristol Myers Squibb Co |
Hepatitis c virus inhibitors
|
US20040138109A1
(en)
*
|
2002-09-30 |
2004-07-15 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Potent inhibitor of HCV serine protease
|
EP1408031A1
(en)
*
|
2002-10-09 |
2004-04-14 |
3 D Gene Pharma |
Pyrolidine derivatives useful in treatment of hepatitis C virus infection
|
US20050075279A1
(en)
*
|
2002-10-25 |
2005-04-07 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
US20050159345A1
(en)
*
|
2002-10-29 |
2005-07-21 |
Boehringer Ingelheim International Gmbh |
Composition for the treatment of infection by Flaviviridae viruses
|
DE60318954T2
(de)
*
|
2002-10-29 |
2009-01-22 |
Boehringer Ingelheim International Gmbh |
Inhibitor-resistente hcv-ns3-protease
|
US7601709B2
(en)
|
2003-02-07 |
2009-10-13 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic hepatitis C serine protease inhibitors
|
EP1590442A4
(en)
*
|
2003-02-07 |
2007-07-18 |
Enanta Pharm Inc |
MACROCYCLIC HEPATITIS C SERIN PROTEASE INHIBITORS
|
UY28240A1
(es)
*
|
2003-03-27 |
2004-11-08 |
Boehringer Ingelheim Pharma |
Fases cristalinas de un potente inhibidor de la hcv
|
UA81028C2
(en)
*
|
2003-04-02 |
2007-11-26 |
Boehringer Ingelheim Int |
Pharmaceutical compositions for hepatitis c viral protease inhibitors
|
US7148347B2
(en)
|
2003-04-10 |
2006-12-12 |
Boehringer Ingelheim International Gmbh |
Process for preparing macrocyclic compounds
|
CN1771257A
(zh)
*
|
2003-04-10 |
2006-05-10 |
贝林格尔·英格海姆国际有限公司 |
通过钌络合物催化的易位反应制备大环化合物的方法
|
JP4733023B2
(ja)
|
2003-04-16 |
2011-07-27 |
ブリストル−マイヤーズ スクイブ カンパニー |
C型肝炎ウイルスの大環状イソキノリンペプチド阻害剤
|
US7176208B2
(en)
|
2003-04-18 |
2007-02-13 |
Enanta Pharmaceuticals, Inc. |
Quinoxalinyl macrocyclic hepatitis C serine protease inhibitors
|
ES2535147T3
(es)
*
|
2003-04-18 |
2015-05-06 |
Enanta Pharmaceuticals, Inc. |
Compuestos macrocíclicos de quinoxalinilo que inhiben las serina proteasas de la hepatitis C
|
NZ544076A
(en)
|
2003-05-21 |
2009-04-30 |
Boehringer Ingelheim Int |
Hepatitis C inhibitor compounds
|
US7273851B2
(en)
|
2003-06-05 |
2007-09-25 |
Enanta Pharmaceuticals, Inc. |
Tri-peptide hepatitis C serine protease inhibitors
|
US7125845B2
(en)
*
|
2003-07-03 |
2006-10-24 |
Enanta Pharmaceuticals, Inc. |
Aza-peptide macrocyclic hepatitis C serine protease inhibitors
|
UY28500A1
(es)
|
2003-09-05 |
2005-04-29 |
Vertex Pharma |
Inhibidores de proteasas de serina, en particular proteasa ns3-ns4a del vhc.
|
KR20060094083A
(ko)
*
|
2003-09-22 |
2006-08-28 |
베링거 인겔하임 인터내셔날 게엠베하 |
C형 간염 바이러스에 대해 활성인 마크로사이클릭펩타이드
|
BRPI0414814A
(pt)
|
2003-09-26 |
2006-11-14 |
Schering Corp |
inibidores macrocìclicos de protease de serina ns3 de vìrus de hepatite c
|
JP2007532474A
(ja)
|
2003-10-10 |
2007-11-15 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
セリンプロテアーゼ、特にhcvのns3−ns4aプロテアーゼの阻害剤
|
WO2005037214A2
(en)
|
2003-10-14 |
2005-04-28 |
Intermune, Inc. |
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication
|
EP1944042A1
(en)
|
2003-10-27 |
2008-07-16 |
Vertex Pharmceuticals Incorporated |
Combinations for HCV treatment
|
JP4890254B2
(ja)
|
2003-10-27 |
2012-03-07 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Hcvns3−ns4aプロテアーゼ耐性突然変異体
|
US8187874B2
(en)
|
2003-10-27 |
2012-05-29 |
Vertex Pharmaceuticals Incorporated |
Drug discovery method
|
US7132504B2
(en)
|
2003-11-12 |
2006-11-07 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
JP2007516239A
(ja)
|
2003-11-20 |
2007-06-21 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
特に複分解反応生成物からの、遷移金属の除去方法
|
US7135462B2
(en)
|
2003-11-20 |
2006-11-14 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7309708B2
(en)
*
|
2003-11-20 |
2007-12-18 |
Birstol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7253160B2
(en)
|
2003-11-20 |
2007-08-07 |
Schering Corporation |
Depeptidized inhibitors of hepatitis C virus NS3 protease
|
ATE424926T1
(de)
*
|
2003-12-08 |
2009-03-15 |
Boehringer Ingelheim Int |
Abtrennung von ruthenium-nebenprodukten durch behandlung mit überkritischen flüssigkeiten
|
GB0500020D0
(en)
|
2005-01-04 |
2005-02-09 |
Novartis Ag |
Organic compounds
|
DE602005025855D1
(de)
*
|
2004-01-21 |
2011-02-24 |
Boehringer Ingelheim Pharma |
Makrocyclische peptide mit wirkung gegen das hepatitis-c-virus
|
ATE416187T1
(de)
*
|
2004-01-28 |
2008-12-15 |
Boehringer Ingelheim Int |
Verfahren zum entfernen von übergangsmetallen aus übergangsmetallnebenprodukte enthaltenden reaktionslösungen
|
RS51243B
(sr)
*
|
2004-01-30 |
2010-12-31 |
Medivir Ab. |
Inhibitori ns-3 serina hcv proteaze
|
AU2011203349B2
(en)
*
|
2004-01-30 |
2012-05-24 |
Medivir Ab |
HCV NS-3 serine protease inhibitors
|
CA2554999A1
(en)
|
2004-02-04 |
2005-08-25 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
|
US20050182252A1
(en)
|
2004-02-13 |
2005-08-18 |
Reddy K. R. |
Novel 2'-C-methyl nucleoside derivatives
|
KR101320907B1
(ko)
|
2004-02-20 |
2013-10-22 |
베링거 인겔하임 인터내셔날 게엠베하 |
바이러스 폴리머라제 억제제
|
US20070049593A1
(en)
|
2004-02-24 |
2007-03-01 |
Japan Tobacco Inc. |
Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor
|
ATE438622T1
(de)
|
2004-02-27 |
2009-08-15 |
Schering Corp |
3,4-(cyclopentyl)kondensierte prolinverbindungen als inhibitoren der ns3-serinprotease des hepatitis-c-virus
|
ATE478889T1
(de)
|
2004-02-27 |
2010-09-15 |
Schering Corp |
Neuartige verbindungen als hemmer von hepatitis c-virus ns3-serinprotease
|
TW200536528A
(en)
|
2004-02-27 |
2005-11-16 |
Schering Corp |
Novel inhibitors of hepatitis C virus NS3 protease
|
JP2007525521A
(ja)
*
|
2004-02-27 |
2007-09-06 |
シェーリング コーポレイション |
C型肝炎ウイルスns3セリンプロテアーゼのインヒビターとしてのシクロブテンジオン基含有化合物
|
US7635694B2
(en)
|
2004-02-27 |
2009-12-22 |
Schering Corporation |
Cyclobutenedione-containing compounds as inhibitors of hepatitis C virus NS3 serine protease
|
US7192957B2
(en)
|
2004-02-27 |
2007-03-20 |
Schering Corporation |
Compounds as inhibitors of hepatitis C virus NS3 serine protease
|
RU2006136084A
(ru)
*
|
2004-03-15 |
2008-04-27 |
БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) |
Способ получения микроциклических соединений
|
AU2005228894B9
(en)
*
|
2004-03-30 |
2011-10-13 |
Intermune, Inc. |
Macrocyclic compounds as inhibitors of viral replication
|
CA2566610A1
(en)
|
2004-05-20 |
2005-12-01 |
Schering Corporation |
Substituted prolines as inhibitors of hepatitis c virus ns3 serine protease
|
US7534767B2
(en)
|
2004-06-15 |
2009-05-19 |
Merck & Co., Inc. |
C-purine nucleoside analogs as inhibitors of RNA-dependent RNA viral polymerase
|
AU2005267421B2
(en)
|
2004-06-24 |
2010-06-03 |
Merck Sharp & Dohme Corp. |
Nucleoside aryl phosphoramidates for the treatment of RNA-dependent RNA viral infection
|
EP1778702B1
(en)
*
|
2004-07-16 |
2011-07-13 |
Gilead Sciences, Inc. |
Antiviral compounds
|
UY29016A1
(es)
|
2004-07-20 |
2006-02-24 |
Boehringer Ingelheim Int |
Analogos de dipeptidos inhibidores de la hepatitis c
|
CA2573346C
(en)
|
2004-07-20 |
2011-09-20 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibitor peptide analogs
|
WO2006026352A1
(en)
|
2004-08-27 |
2006-03-09 |
Schering Corporation |
Acylsulfonamide compounds as inhibitors of hepatitis c virus ns3 serine protease
|
CA2578428A1
(en)
*
|
2004-09-17 |
2006-03-30 |
Boehringer Ingelheim International Gmbh |
Ring-closing metathesis process in supercritical fluid
|
WO2006033878A1
(en)
*
|
2004-09-17 |
2006-03-30 |
Boehringer Ingelheim International, Gmbh |
Process for preparing macrocyclic hcv protease inhibitors
|
WO2006036614A2
(en)
*
|
2004-09-24 |
2006-04-06 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
A new class of surfactant-like materials comprising vitamin e tpgs and a water soluble polymer
|
CA2583152A1
(en)
*
|
2004-10-21 |
2006-04-27 |
Pfizer Inc. |
Inhibitors of hepatitis c virus protease, and compositions and treatments using the same
|
US7659263B2
(en)
|
2004-11-12 |
2010-02-09 |
Japan Tobacco Inc. |
Thienopyrrole compound and use thereof as HCV polymerase inhibitor
|
DK1835951T3
(da)
|
2004-12-20 |
2011-04-18 |
Codman & Shurtleff |
HCV-inhibitor til anvendelse ved en fremgangsmåde til behandling af hepatitis C
|
DE102005002336A1
(de)
|
2005-01-17 |
2006-07-20 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Durchführung von kontinuierlichen Olefin-Ringschluss-Metathesen in komprimiertem Kohlendioxid
|
US7323447B2
(en)
|
2005-02-08 |
2008-01-29 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
EP2332963A3
(en)
*
|
2005-03-08 |
2011-11-16 |
Boehringer Ingelheim International Gmbh |
Process for preparing macrocyclic compounds
|
US7879797B2
(en)
|
2005-05-02 |
2011-02-01 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
US7592336B2
(en)
|
2005-05-10 |
2009-09-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
NZ563909A
(en)
|
2005-05-13 |
2011-10-28 |
Virochem Pharma Inc |
Thiophene derivatives and their use for the treatment or prevention of flavivirus infections
|
PL1891089T3
(pl)
|
2005-06-02 |
2015-05-29 |
Merck Sharp & Dohme |
Inhibitory proteazy HCV w połączeniu z pokarmem
|
WO2006130666A2
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Medicaments and methods combining a hcv protease inhibitor and an akr competitor
|
CA2611155A1
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Pharmaceutical formulations and methods of treatment using the same
|
US7608592B2
(en)
|
2005-06-30 |
2009-10-27 |
Virobay, Inc. |
HCV inhibitors
|
US7601686B2
(en)
|
2005-07-11 |
2009-10-13 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7470664B2
(en)
*
|
2005-07-20 |
2008-12-30 |
Merck & Co., Inc. |
HCV NS3 protease inhibitors
|
EP1924594A2
(en)
|
2005-07-25 |
2008-05-28 |
Intermune, Inc. |
Novel macrocyclic inhibitors of hepatitis c virus replication
|
JO2768B1
(en)
*
|
2005-07-29 |
2014-03-15 |
تيبوتيك فارماسيوتيكالز ليمتد |
Large cyclic inhibitors of hepatitis C virus
|
BRPI0614620A2
(pt)
*
|
2005-07-29 |
2011-04-12 |
Tibotec Pharm Ltd |
compostos inibidores macrocìclicos do vìrus da hepatite c, uso dos mesmos, processo para preparar os referidos compostos, combinação e composição farmacêutica
|
PE20070211A1
(es)
*
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
PE20070343A1
(es)
*
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Inhibidores macrociclicos del virus de la hepatitis c
|
AR055361A1
(es)
*
|
2005-07-29 |
2007-08-22 |
Medivir Ab |
Inhibidores macrociclicos del virus de la hepatitis c
|
PE20070210A1
(es)
*
|
2005-07-29 |
2007-04-16 |
Tibotec Pharm Ltd |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
UA95239C2
(ru)
*
|
2005-07-29 |
2011-07-25 |
Тиботек Фармасьютикелз Лтд. |
Макроциклические ингибиторы вируса гепатита с
|
EA014293B1
(ru)
*
|
2005-07-29 |
2010-10-29 |
Тиботек Фармасьютикалз Лтд. |
Макроциклические ингибиторы вируса гепатита с
|
SI1913015T1
(sl)
*
|
2005-07-29 |
2014-05-30 |
Janssen R&D Ireland |
Makrociklični inhibitorji virusa Hepatitis C
|
PL1919904T3
(pl)
|
2005-07-29 |
2014-06-30 |
Janssen R&D Ireland |
Makrocykliczne inhibitory wirusa zapalenia wątroby typu C
|
AR055105A1
(es)
*
|
2005-07-29 |
2007-08-08 |
Tibotec Pharm Ltd |
Inhibidores macrociclicos del virus de la hepatitis c
|
JP4705984B2
(ja)
|
2005-08-01 |
2011-06-22 |
メルク・シャープ・エンド・ドーム・コーポレイション |
Hcvns3プロテアーゼ阻害剤としての大環状ペプチド
|
CA2617679A1
(en)
|
2005-08-02 |
2007-02-08 |
Steve Lyons |
Inhibitors of serine proteases
|
JP2009513564A
(ja)
|
2005-08-09 |
2009-04-02 |
メルク エンド カムパニー インコーポレーテッド |
Rna依存性rnaウイルス感染の治療用のリボヌクレオシド環状アセタール誘導体
|
WO2007019674A1
(en)
|
2005-08-12 |
2007-02-22 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
ATE463480T1
(de)
|
2005-08-19 |
2010-04-15 |
Vertex Pharma |
Verfahren und zwischenprodukte
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
WO2007044893A2
(en)
|
2005-10-11 |
2007-04-19 |
Intermune, Inc. |
Compounds and methods for inhibiting hepatitis c viral replication
|
US7772183B2
(en)
|
2005-10-12 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7741281B2
(en)
|
2005-11-03 |
2010-06-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7705138B2
(en)
|
2005-11-11 |
2010-04-27 |
Vertex Pharmaceuticals Incorporated |
Hepatitis C virus variants
|
EP1951748B1
(en)
|
2005-11-11 |
2013-07-24 |
Vertex Pharmaceuticals, Inc. |
Hepatitis c virus variants
|
US7816348B2
(en)
|
2006-02-03 |
2010-10-19 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
GB0609492D0
(en)
|
2006-05-15 |
2006-06-21 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
US8268776B2
(en)
|
2006-06-06 |
2012-09-18 |
Enanta Pharmaceuticals, Inc. |
Macrocylic oximyl hepatitis C protease inhibitors
|
US9526769B2
(en)
|
2006-06-06 |
2016-12-27 |
Enanta Pharmaceuticals, Inc. |
Macrocylic oximyl hepatitis C protease inhibitors
|
GB0612423D0
(en)
|
2006-06-23 |
2006-08-02 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
PE20080992A1
(es)
*
|
2006-06-26 |
2008-08-06 |
Enanta Pharm Inc |
Quinoxalinil macrociclicos inhibidores de serina proteasa del virus de la hepatitis c
|
KR20090024834A
(ko)
|
2006-07-05 |
2009-03-09 |
인터뮨, 인크. |
C형 간염 바이러스 복제의 신규 억제제
|
EP2049474B1
(en)
|
2006-07-11 |
2015-11-04 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
JP5517614B2
(ja)
*
|
2006-07-13 |
2014-06-11 |
アキリオン ファーマシューティカルズ,インコーポレーテッド |
ウイルス複製阻害剤としての4−アミノ−4−オキソブタノイルペプチド類
|
EP1886685A1
(en)
|
2006-08-11 |
2008-02-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods, uses and compositions for modulating replication of hcv through the farnesoid x receptor (fxr) activation or inhibition
|
BRPI0716060A2
(pt)
|
2006-08-17 |
2013-09-17 |
Boehringer Ingelheim Int |
inibidores de polimerase viral.
|
EP2079479B1
(en)
|
2006-10-24 |
2014-11-26 |
Merck Sharp & Dohme Corp. |
Hcv ns3 protease inhibitors
|
CA2667266C
(en)
|
2006-10-24 |
2015-11-24 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
AU2007309546A1
(en)
|
2006-10-24 |
2008-05-02 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
HCV NS3 protease inhibitors
|
US8377874B2
(en)
|
2006-10-27 |
2013-02-19 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
US20100099695A1
(en)
|
2006-10-27 |
2010-04-22 |
Liverton Nigel J |
HCV NS3 Protease Inhibitors
|
US8343477B2
(en)
|
2006-11-01 |
2013-01-01 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus
|
US7772180B2
(en)
|
2006-11-09 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
CN102250074A
(zh)
|
2006-11-15 |
2011-11-23 |
沃泰克斯药物(加拿大)股份有限公司 |
用于治疗或预防黄病毒属感染的噻吩类似物
|
US7763584B2
(en)
|
2006-11-16 |
2010-07-27 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US8003604B2
(en)
|
2006-11-16 |
2011-08-23 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7888464B2
(en)
|
2006-11-16 |
2011-02-15 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
WO2008059046A1
(en)
|
2006-11-17 |
2008-05-22 |
Tibotec Pharmaceuticals Ltd. |
Macrocyclic inhibitors of hepatitis c virus
|
GB0625345D0
(en)
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
GB0625349D0
(en)
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
EP2121707B1
(en)
|
2006-12-20 |
2012-12-05 |
Istituto di Ricerche di Biologia Molecolare P. Angeletti S.R.L. |
Antiviral indoles
|
BRPI0806853B1
(pt)
|
2007-02-01 |
2018-03-20 |
Janssen Sciences Ireland Uc |
Processos e intermediários para preparar um inibidor de protease macrocíclico de hcv
|
CA2677697A1
(en)
*
|
2007-02-08 |
2008-07-14 |
Tibotec Pharmaceuticals Ltd. |
Pyrimidine substituted macrocyclic hcv inhibitors
|
CN101627020B
(zh)
*
|
2007-02-08 |
2015-06-17 |
泰博特克药品有限公司 |
抑制hcv的大环苯基氨基甲酸酯
|
CA2679377A1
(en)
*
|
2007-02-26 |
2008-09-04 |
Achillion Pharmaceuticals, Inc. |
Tertiary amine substituted peptides useful as inhibitors of hcv replication
|
US8258116B2
(en)
|
2007-05-04 |
2012-09-04 |
Vertex Pharmaceuticals Incorporated |
Combination therapy for the treatment of HCV infection
|
MX2009012093A
(es)
|
2007-05-10 |
2010-01-25 |
Intermune Inc |
Nuevos peptidos inhibidores de la replicacion del virus de la hepatitis c.
|
BRPI0813733A2
(pt)
|
2007-06-29 |
2019-11-05 |
Gilead Sciences Inc |
composto com atividade inibidora de hcv, sua composição farmacêutica e seu uso.
|
CA2691442C
(en)
*
|
2007-06-29 |
2014-01-21 |
Gilead Sciences, Inc. |
Antiviral compounds
|
CA2693537C
(en)
|
2007-07-17 |
2013-06-25 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa |
Macrocyclic indole derivatives for the treatment of hepatitis c infections
|
US8927569B2
(en)
|
2007-07-19 |
2015-01-06 |
Merck Sharp & Dohme Corp. |
Macrocyclic compounds as antiviral agents
|
CA2693997C
(en)
|
2007-08-03 |
2013-01-15 |
Pierre L. Beaulieu |
Viral polymerase inhibitors
|
GB0718575D0
(en)
|
2007-09-24 |
2007-10-31 |
Angeletti P Ist Richerche Bio |
Nucleoside derivatives as inhibitors of viral polymerases
|
US8383583B2
(en)
|
2007-10-26 |
2013-02-26 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic, pyridazinone-containing hepatitis C serine protease inhibitors
|
EP2224942A4
(en)
|
2007-12-05 |
2012-01-25 |
Enanta Pharm Inc |
FLUORATED TRIPEPTIDE HCV SERINE PROTEASE INHIBITORS
|
WO2009073780A1
(en)
|
2007-12-06 |
2009-06-11 |
Enanta Pharmaceuticals, Inc. |
Process for making macrocyclic oximyl hepatitis c protease inhibitors
|
MX2010006313A
(es)
|
2007-12-19 |
2010-06-25 |
Boehringer Ingelheim Int |
Inhibidores de la polimerasa virica.
|
US8202996B2
(en)
|
2007-12-21 |
2012-06-19 |
Bristol-Myers Squibb Company |
Crystalline forms of N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-((7-chloro-4-methoxy-1-isoquinolinyl)oxy)-N- ((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-L-prolinamide
|
KR20100118991A
(ko)
|
2008-02-04 |
2010-11-08 |
아이데닉스 파마슈티칼스, 인코포레이티드 |
매크로시클릭 세린 프로테아제 억제제
|
US8372802B2
(en)
|
2008-03-20 |
2013-02-12 |
Enanta Pharmaceuticals, Inc. |
Fluorinated macrocyclic compounds as hepatitis C virus inhibitors
|
CA2720729A1
(en)
|
2008-04-15 |
2009-11-26 |
Intermune, Inc. |
Novel macrocyclic inhibitors of hepatitis c virus replication
|
US8163921B2
(en)
|
2008-04-16 |
2012-04-24 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
WO2009134624A1
(en)
|
2008-04-28 |
2009-11-05 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
US7964560B2
(en)
|
2008-05-29 |
2011-06-21 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
WO2009148923A1
(en)
*
|
2008-05-29 |
2009-12-10 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
DK2310095T3
(da)
|
2008-07-22 |
2012-12-10 |
Merck Sharp & Dohme |
Makrocykliske quinoxalinforbindelser som hcv-ns3-protease-inhibitorer
|
US8207341B2
(en)
|
2008-09-04 |
2012-06-26 |
Bristol-Myers Squibb Company |
Process or synthesizing substituted isoquinolines
|
UY32099A
(es)
|
2008-09-11 |
2010-04-30 |
Enanta Pharm Inc |
Inhibidores macrocíclicos de serina proteasas de hepatitis c
|
SI2331538T1
(sl)
|
2008-09-16 |
2014-06-30 |
Boehringer Ingelheim International Gmbh |
Kristalinične oblike 2-tiazolil-4-kinolinil-oksi derivata, učinkovitega inhibitorja HCV
|
US8044087B2
(en)
|
2008-09-29 |
2011-10-25 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US8563505B2
(en)
|
2008-09-29 |
2013-10-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
EP2341924A4
(en)
|
2008-10-02 |
2013-01-23 |
David Gladstone Inst |
METHOD FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTIONS
|
SI2350071T1
(sl)
|
2008-10-22 |
2014-05-30 |
Array Biopharma, Inc. |
Substituirane pirazolo(1,5-a)pirimidinske spojine kot Trk kinazni inhibitorji
|
AU2009316472B2
(en)
*
|
2008-11-20 |
2015-07-09 |
Achillion Pharmaceuticals, Inc. |
Cyclic carboxamide compounds and analogues thereof as of Hepatitis C virus
|
WO2010068761A2
(en)
*
|
2008-12-10 |
2010-06-17 |
Achillion Pharmaceuticals, Inc. |
4-amino-4-oxobutanoyl peptide cyclic analogues, inhibitors of viral replication
|
DK2364309T3
(en)
|
2008-12-10 |
2015-01-12 |
Achillion Pharmaceuticals Inc |
NEW 4-AMINO-4-OXOBUTANOYLPEPTIDER as inhibitors of viral replication
|
US8283310B2
(en)
|
2008-12-15 |
2012-10-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
JP2012514605A
(ja)
|
2009-01-07 |
2012-06-28 |
サイネクシス,インコーポレーテッド |
Hcvおよびhiv感染の治療への使用におけるシクロスポリン誘導体
|
WO2010082050A1
(en)
|
2009-01-16 |
2010-07-22 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Macrocyclic and 7-aminoalkyl-substituted benzoxazocines for treatment of hepatitis c infections
|
GB0900914D0
(en)
|
2009-01-20 |
2009-03-04 |
Angeletti P Ist Richerche Bio |
Antiviral agents
|
AR075584A1
(es)
|
2009-02-27 |
2011-04-20 |
Intermune Inc |
COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO.
|
JP5690286B2
(ja)
|
2009-03-04 |
2015-03-25 |
イデニク プハルマセウティカルス,インコーポレイテッド |
ホスホチオフェン及びホスホチアゾールhcvポリメラーゼ阻害剤
|
WO2010107739A2
(en)
|
2009-03-18 |
2010-09-23 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions of treating a flaviviridae family viral infection
|
JP2012523419A
(ja)
|
2009-04-08 |
2012-10-04 |
イデニク プハルマセウティカルス,インコーポレイテッド |
大環状セリンプロテアーゼ阻害剤
|
WO2010132163A1
(en)
|
2009-05-13 |
2010-11-18 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic compounds as hepatitis c virus inhibitors
|
US8232246B2
(en)
|
2009-06-30 |
2012-07-31 |
Abbott Laboratories |
Anti-viral compounds
|
AR077468A1
(es)
|
2009-07-09 |
2011-08-31 |
Array Biopharma Inc |
Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa
|
US8828930B2
(en)
|
2009-07-30 |
2014-09-09 |
Merck Sharp & Dohme Corp. |
Hepatitis C virus NS3 protease inhibitors
|
CA2769652A1
(en)
|
2009-08-05 |
2011-02-10 |
Idenix Pharmaceuticals, Inc. |
Macrocyclic serine protease inhibitors useful against viral infections, particularly hcv
|
WO2011063076A1
(en)
|
2009-11-19 |
2011-05-26 |
Itherx Pharmaceuticals, Inc. |
Methods of treating hepatitis c virus with oxoacetamide compounds
|
WO2011063501A1
(en)
*
|
2009-11-24 |
2011-06-03 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibitor compounds
|
EP2504344A4
(en)
*
|
2009-11-24 |
2013-06-05 |
Boehringer Ingelheim Int |
HEPATITIS C INHIBITOR COMPOUNDS
|
EP2504329A1
(en)
|
2009-11-25 |
2012-10-03 |
Vertex Pharmaceuticals Incorporated |
5-alkynyl-thiophene-2-carboxylic acid derivatives and their use for the treatment or prevention of flavivirus infections
|
MX2012006877A
(es)
|
2009-12-18 |
2012-08-31 |
Idenix Pharmaceuticals Inc |
Inhibidores de virus de hepatitis c de arileno o heteroarileno 5, 5 - fusionado.
|
WO2011079327A1
(en)
|
2009-12-24 |
2011-06-30 |
Vertex Pharmaceuticals Incorporated |
Analogues for the treatment or prevention of flavivirus infections
|
EP2550267A1
(en)
|
2010-03-24 |
2013-01-30 |
Vertex Pharmaceuticals Incorporated |
Analogues for the treatment or prevention of flavivirus infections
|
EP2550268A1
(en)
|
2010-03-24 |
2013-01-30 |
Vertex Pharmaceuticals Incorporated |
Analogues for the treatment or prevention of flavivirus infections
|
WO2011119858A1
(en)
|
2010-03-24 |
2011-09-29 |
Vertex Pharmaceuticals Incorporated |
Analogues for the treatment or prevention of flavivirus infections
|
TW201200522A
(en)
|
2010-03-24 |
2012-01-01 |
Vertex Pharma |
Analogues for the treatment or prevention of flavivirus infections
|
ES2628418T3
(es)
*
|
2010-05-20 |
2017-08-02 |
Array Biopharma, Inc. |
Compuestos macrocíclicos como inhibidores de la TRK cinasa
|
WO2011156545A1
(en)
|
2010-06-09 |
2011-12-15 |
Vertex Pharmaceuticals Incorporated |
Viral dynamic model for hcv combination therapy
|
WO2011159826A2
(en)
|
2010-06-15 |
2011-12-22 |
Vertex Pharmaceuticals Incorporated |
Hcv ns5b protease mutants
|
CA2803248A1
(en)
|
2010-06-28 |
2012-01-12 |
Vertex Pharmaceuticals Incorporated |
Compounds and methods for the treatment or prevention of flavivirus infections
|
WO2012006070A1
(en)
|
2010-06-28 |
2012-01-12 |
Vertex Pharmaceuticals Incorporated |
Compounds and methods for the treatment or prevention of flavivirus infections
|
WO2012006060A1
(en)
|
2010-06-28 |
2012-01-12 |
Vertex Pharmaceuticals Incorporated |
Compounds and methods for the treatment or prevention of flavivirus infections
|
MX2013001869A
(es)
|
2010-08-17 |
2013-06-28 |
Vertex Pharma |
Compuestos y metodos para el tratamiento o prevencion de infecciones virales por flaviviridae.
|
PT2618831E
(pt)
|
2010-09-21 |
2016-03-04 |
Enanta Pharm Inc |
Inibidores de serina-protease do vhc derivados de prolina macrocíclica
|
SG191759A1
(en)
*
|
2010-12-30 |
2013-08-30 |
Enanta Pharm Inc |
Phenanthridine macrocyclic hepatitis c serine protease inhibitors
|
CA2822556A1
(en)
|
2010-12-30 |
2012-07-05 |
Enanta Pharmaceuticals, Inc |
Macrocyclic hepatitis c serine protease inhibitors
|
US9353100B2
(en)
|
2011-02-10 |
2016-05-31 |
Idenix Pharmaceuticals Llc |
Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating HCV infections
|
WO2012107589A1
(en)
|
2011-02-11 |
2012-08-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment and prevention of hcv infections
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
US8957203B2
(en)
|
2011-05-05 |
2015-02-17 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US10201584B1
(en)
|
2011-05-17 |
2019-02-12 |
Abbvie Inc. |
Compositions and methods for treating HCV
|
US8691757B2
(en)
|
2011-06-15 |
2014-04-08 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
WO2013016499A1
(en)
|
2011-07-26 |
2013-01-31 |
Vertex Pharmaceuticals Incorporated |
Methods for preparation of thiophene compounds
|
WO2013016490A1
(en)
|
2011-07-26 |
2013-01-31 |
Vertex Pharmaceuticals Incorporated |
Thiophene compounds
|
US9328138B2
(en)
|
2011-11-15 |
2016-05-03 |
Msd Italia S.R.L. |
HCV NS3 protease inhibitors
|
EP2787999B1
(en)
|
2011-12-06 |
2019-01-23 |
The Board of Trustees of The Leland Stanford Junior University |
Methods and compositions for treating viral diseases
|
KR20140114827A
(ko)
*
|
2012-01-11 |
2014-09-29 |
에프. 호프만-라 로슈 아게 |
프로테아제 억제제로서 매크로사이클릭 아미드
|
US20140356325A1
(en)
|
2012-01-12 |
2014-12-04 |
Ligand Pharmaceuticals Incorporated |
Novel 2'-c-methyl nucleoside derivative compounds
|
NZ630805A
(en)
|
2012-03-22 |
2016-01-29 |
Alios Biopharma Inc |
Pharmaceutical combinations comprising a thionucleotide analog
|
BR112015007879A2
(pt)
*
|
2012-10-19 |
2017-07-04 |
Bristol Myers Squibb Co |
inibidores do vírus da hepatite c
|
US9643999B2
(en)
*
|
2012-11-02 |
2017-05-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
WO2014070964A1
(en)
|
2012-11-02 |
2014-05-08 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
US9334279B2
(en)
|
2012-11-02 |
2016-05-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
EP2914614B1
(en)
|
2012-11-05 |
2017-08-16 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
WO2014121417A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
WO2014121418A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
US20150065439A1
(en)
|
2013-02-28 |
2015-03-05 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions
|
US9580463B2
(en)
|
2013-03-07 |
2017-02-28 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
WO2014138374A1
(en)
|
2013-03-08 |
2014-09-12 |
Boehringer Ingelheim International Gmbh |
Oral combination therapy for treating hcv infection in specific patient sub-population
|
WO2014145507A1
(en)
|
2013-03-15 |
2014-09-18 |
Achillion Pharmaceuticals, Inc. |
A process for making a 4-amino-4-oxobutanoyl peptide cyclic analogue, an inhibitor of viral replication, and intermediates thereof
|
WO2014145600A1
(en)
|
2013-03-15 |
2014-09-18 |
Achillion Pharmaceuticals, Inc. |
Ach-0142684 sodium salt polymorphs, composition including the same, and method of manufacture thereof
|
WO2015042375A1
(en)
|
2013-09-20 |
2015-03-26 |
Idenix Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
WO2015103490A1
(en)
|
2014-01-03 |
2015-07-09 |
Abbvie, Inc. |
Solid antiviral dosage forms
|
WO2015134561A1
(en)
|
2014-03-05 |
2015-09-11 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
|
EP3114122A1
(en)
|
2014-03-05 |
2017-01-11 |
Idenix Pharmaceuticals LLC |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
CN113354649A
(zh)
|
2014-11-16 |
2021-09-07 |
阵列生物制药公司 |
一种新的晶型
|
US10724102B2
(en)
|
2015-10-26 |
2020-07-28 |
Loxo Oncology, Inc. |
Point mutations in TRK inhibitor-resistant cancer and methods relating to the same
|
US10045991B2
(en)
|
2016-04-04 |
2018-08-14 |
Loxo Oncology, Inc. |
Methods of treating pediatric cancers
|
CU20180125A7
(es)
|
2016-04-04 |
2019-05-03 |
Loxo Oncology Inc |
Formulaciones líquidas de (s)-n-(5-((r)-2-(2,5-difluorofenil) -pirrolidin-1-il)-pirazolo[1,5-alpirimidin-3-il)-3 hidroxipirrolidina-1-carboxamida
|
AU2017268371B2
(en)
|
2016-05-18 |
2020-11-19 |
Array Biopharma Inc. |
Preparation of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo(1,5-A)pyrimidin-3-y l)-3-hydroxypyrrolidine-1-carboxamide
|
JOP20190092A1
(ar)
|
2016-10-26 |
2019-04-25 |
Array Biopharma Inc |
عملية لتحضير مركبات بيرازولو[1، 5-a]بيريميدين وأملاح منها
|
CN108059625A
(zh)
*
|
2016-11-09 |
2018-05-22 |
广东广康生化科技股份有限公司 |
一种由噻唑酸制备噻呋酰胺的新型工艺
|
JOP20190213A1
(ar)
|
2017-03-16 |
2019-09-16 |
Array Biopharma Inc |
مركبات حلقية ضخمة كمثبطات لكيناز ros1
|
US11091427B2
(en)
|
2017-03-24 |
2021-08-17 |
Agency For Science, Technology And Research |
Building blocks for stapled peptides
|
WO2022240541A1
(en)
*
|
2021-05-11 |
2022-11-17 |
Enanta Pharmaceuticals, Inc. |
Novel macrocyclic spiropyrrolidine derived antiviral agents
|
WO2023086352A1
(en)
|
2021-11-12 |
2023-05-19 |
Enanta Pharmaceuticals, Inc. |
Novel spiropyrrolidine derived antiviral agents
|
US11919910B2
(en)
|
2021-11-12 |
2024-03-05 |
Enanta Pharmaceuticals, Inc. |
Spiropyrrolidine derived antiviral agents
|
WO2023086350A1
(en)
|
2021-11-12 |
2023-05-19 |
Enanta Pharmaceuticals, Inc. |
Alkyne-containing antiviral agents
|