SE8501693D0 - Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters - Google Patents

Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters

Info

Publication number
SE8501693D0
SE8501693D0 SE8501693A SE8501693A SE8501693D0 SE 8501693 D0 SE8501693 D0 SE 8501693D0 SE 8501693 A SE8501693 A SE 8501693A SE 8501693 A SE8501693 A SE 8501693A SE 8501693 D0 SE8501693 D0 SE 8501693D0
Authority
SE
Sweden
Prior art keywords
sub
hydrogen
straight
compounds
carbon atoms
Prior art date
Application number
SE8501693A
Other languages
English (en)
Swedish (sv)
Inventor
P H Andersson
P T Andersson
B I Axelsson
B A Thalen
J W Trofast
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Priority to SE8501693A priority Critical patent/SE8501693D0/xx
Publication of SE8501693D0 publication Critical patent/SE8501693D0/xx
Priority to ZA861884A priority patent/ZA861884B/xx
Priority to IL78143A priority patent/IL78143A0/xx
Priority to AU54868/86A priority patent/AU590545B2/en
Priority to DE8686850103T priority patent/DE3687239T2/de
Priority to DE3689936T priority patent/DE3689936T2/de
Priority to AT86850103T priority patent/ATE83241T1/de
Priority to EP89116726A priority patent/EP0355859B1/en
Priority to AT89116726T priority patent/ATE107657T1/de
Priority to EP86850103A priority patent/EP0197018B1/en
Priority to US06/843,771 priority patent/US4950659A/en
Priority to NZ230570A priority patent/NZ230570A/en
Priority to DK138386A priority patent/DK165638C/da
Priority to FI861275A priority patent/FI85378C/fi
Priority to NZ215586A priority patent/NZ215586A/en
Priority to JO19861479A priority patent/JO1479B1/en
Priority to CS862328A priority patent/CS266581B2/cs
Priority to UA4027252A priority patent/UA13319A/uk
Priority to UA4027897A priority patent/UA19288A/ru
Priority to IE87986A priority patent/IE61474B1/en
Priority to SU864027252A priority patent/RU1795972C/ru
Priority to CA000505744A priority patent/CA1333597C/en
Priority to IE930680A priority patent/IE66261B1/en
Priority to JP61075677A priority patent/JPH0762028B2/ja
Priority to ES553675A priority patent/ES8800264A1/es
Priority to HU884925A priority patent/HU199872B/hu
Priority to DD86288744A priority patent/DD247681A5/de
Priority to KR1019860002523A priority patent/KR930009444B1/ko
Priority to HU861423A priority patent/HU196830B/hu
Priority to NO861313A priority patent/NO165298C/no
Priority to PL1986265699A priority patent/PL150052B1/pl
Priority to PL1986258775A priority patent/PL148272B1/pl
Priority to CN86102193A priority patent/CN1021444C/zh
Priority to GR860902A priority patent/GR860902B/el
Priority to PT82340A priority patent/PT82340B/pt
Priority to SU864027897A priority patent/RU1779257C/ru
Priority to NO864917A priority patent/NO165680C/no
Priority to ES557314A priority patent/ES8802392A1/es
Priority to DD87305598A priority patent/DD261364A5/de
Priority to PH35610A priority patent/PH23547A/en
Priority to NO873567A priority patent/NO167294C/no
Priority to MYPI87001991A priority patent/MY102056A/en
Priority to CS883736A priority patent/CS268550B2/cs
Priority to PH37057A priority patent/PH24369A/en
Priority to CA000589467A priority patent/CA1334845C/en
Priority to FI910379A priority patent/FI105404B/sv
Priority to SU915001895A priority patent/RU2081879C1/ru
Priority to CN91110725A priority patent/CN1060471A/zh
Priority to DK059392A priority patent/DK167150B1/da
Priority to DK059693A priority patent/DK167574B1/da
Priority to LVP-93-861A priority patent/LV10281B/xx
Priority to LVP-93-818A priority patent/LV10960B/lv
Priority to LVP-93-1006A priority patent/LV10957B/lv
Priority to LTIP1677A priority patent/LT3812B/lt
Priority to LTIP1678A priority patent/LT3913B/lt
Priority to LTIP1676A priority patent/LT3811B/lt
Priority to HK7197A priority patent/HK7197A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Peptides Or Proteins (AREA)
  • Threshing Machine Elements (AREA)
  • Fats And Perfumes (AREA)
SE8501693A 1985-04-04 1985-04-04 Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters SE8501693D0 (sv)

Priority Applications (57)

Application Number Priority Date Filing Date Title
SE8501693A SE8501693D0 (sv) 1985-04-04 1985-04-04 Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
ZA861884A ZA861884B (en) 1985-04-04 1986-03-13 Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
IL78143A IL78143A0 (en) 1985-04-04 1986-03-14 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters,their preparation and pharmaceutical compositions containing them
AU54868/86A AU590545B2 (en) 1985-04-04 1986-03-19 3-oxo-androsta-1,4-diene-17beta-carboxylic acid esters
DE8686850103T DE3687239T2 (de) 1985-04-04 1986-03-21 16,17-acetal-substituierte androstane-17-beta-carbonsaeureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten.
DE3689936T DE3689936T2 (de) 1985-04-04 1986-03-21 Verfahren zur Herstellung von Zwischenprodukten für 11-beta,16-alpha,17-alpha,21-Tetrahydroxypregna-3-20-dione 16-alpha,17-alpha-Acetal und deren 21-Ester.
AT86850103T ATE83241T1 (de) 1985-04-04 1986-03-21 16,17-acetal-substituierte androstane-17-betacarbons|ureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten.
EP89116726A EP0355859B1 (en) 1985-04-04 1986-03-21 Process for the preparation of intermediates for 11-beta,16-alpha,17-alpha,21-tetrahydroxypregna-3,20-dione 16-alpha,17-alpha-acetals and 21-esters thereof
AT89116726T ATE107657T1 (de) 1985-04-04 1986-03-21 Verfahren zur herstellung von zwischenprodukten für 11-beta,16-alpha,17-alpha,21- tetrahydroxypregna-3-20-dione 16-alpha,17-alpha- acetal und deren 21-ester.
EP86850103A EP0197018B1 (en) 1985-04-04 1986-03-21 16,17-acetal-substituted androstane-17-beta-carboxylic-acid esters, process for their preparation and pharmaceutical compound containing them
US06/843,771 US4950659A (en) 1985-04-04 1986-03-25 16,17-acetalsubstituted androstane-17β-carboxylic acid esters prossessing high binding affinity to the glucocorticosteroid receptor
NZ230570A NZ230570A (en) 1985-04-04 1986-03-25 The preparation of intermediate 16,17-acetal substituted androstang-17#b#-carboxylic acid esters
DK138386A DK165638C (da) 1985-04-04 1986-03-25 16,17-acetalsubstituerede androstan-17beta-carboxylsyreestere, fremgangsmaade til fremstilling heraf samt farmaceutisk praeparat indeholdende samme
FI861275A FI85378C (fi) 1985-04-04 1986-03-25 Foerfarande foer framstaellning av farmakologiskt aktiva 16,17-acetalsubstituerade androstan-17 -karboxylsyraestrar.
NZ215586A NZ215586A (en) 1985-04-04 1986-03-25 16,17-acetal-substituted androstane-17#b#-carboxylic acid esters and pharmaceutical compositions
JO19861479A JO1479B1 (en) 1985-04-04 1986-04-01 New Legacy of 16,17 Acid - Through Androstane Replacement - 17 Beta - Carboxylic
CS862328A CS266581B2 (en) 1985-04-04 1986-04-02 Method of 16,17-acetal- substituted androstane-17 beta-carboxyl acids new esters production
UA4027252A UA13319A (uk) 1985-04-04 1986-04-03 СПОСІБ ОДЕРЖАHHЯ СКЛАДHИХ ЕФІРІВ 16,17-АЦЕТАЛЬЗАМІЩЕHОЇ АHДРОСТАH-17beta-КАРБОHОВОЇ КИСЛОТИ
UA4027897A UA19288A (ru) 1985-04-04 1986-04-03 Способ получения стероидных полупродуктов или их 22r/s стереоизомеров
IE87986A IE61474B1 (en) 1985-04-04 1986-04-03 Novel 16,17-acetalsubstituted androstane-17 B-carboxylic acid esters
SU864027252A RU1795972C (ru) 1985-04-04 1986-04-03 Способ получени сложных эфиров 16,17-ацетальзамещенной андростан-17 @ -карбоновой кислоты
CA000505744A CA1333597C (en) 1985-04-04 1986-04-03 16,17-acetalsubstituted androstane-17.beta.-carboxylic acid esters
IE930680A IE66261B1 (en) 1985-04-04 1986-04-03 Preparation of intermediates for 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
JP61075677A JPH0762028B2 (ja) 1985-04-04 1986-04-03 新規１６，１７−アセタ−ル置換アンドロスタン−１７β−カルボン酸エステル
ES553675A ES8800264A1 (es) 1985-04-04 1986-04-03 Un procedimiento para preparar nuevos esteres de acido androstano-17b-carboxilico
HU884925A HU199872B (en) 1985-04-04 1986-04-03 Process for producing 16alpha,17alpha-alkilidenedioxy-11beta-hydroxypregno-1,4-diene-3,20-dione derivatives
DD86288744A DD247681A5 (de) 1985-04-04 1986-04-03 Verfahren zur herstellung von 16,17-acetalsubstituierten androstan-17 beta- carbonsaeureestern
KR1019860002523A KR930009444B1 (ko) 1985-04-04 1986-04-03 신규 16, 17-아세탈 치환 안드로스탄-17β-카르복실산 에스테르의 제조방법
HU861423A HU196830B (en) 1985-04-04 1986-04-03 Process for producing new androstadiene-17-beta-carboxylic acid esters and pharmaceutical compositions comprising them
NO861313A NO165298C (no) 1985-04-04 1986-04-03 Analogifremgangsmaate for fremstilling av nye terapeutisk virksomme 16,17-acetalsubstituerte androstan-17beta-karboksylsyreestere.
PL1986265699A PL150052B1 (en) 1985-04-04 1986-04-04 Method of obtaining novel derivatives of androstanocarboxylic-17 beta acid
PL1986258775A PL148272B1 (en) 1985-04-04 1986-04-04 Method of obtaining novel derivatives of androstanocarboxylic-17 beta acid
CN86102193A CN1021444C (zh) 1985-04-04 1986-04-04 新的16，17-缩醛取代雄甾烷-17β-羧酸酯类的制备方法
GR860902A GR860902B (en) 1985-04-04 1986-04-04 Novel 16,17-acetalsubstituted androstane -17b- carboxylic acid esters
PT82340A PT82340B (pt) 1985-04-04 1986-04-04 Processo para a preparacao de novos esteres do acido androstano-17 beta-carboxilico com um substituinte acetal em posicao 16,17 e de composicoes farmaceuticas que os contem
SU864027897A RU1779257C (ru) 1985-04-04 1986-07-31 Способ получени стероидных полупродуктов или их 22R/S стереоизомеров
NO864917A NO165680C (no) 1985-04-04 1986-12-08 Androstan-17 beta-karboksylsyreforbindelser.
ES557314A ES8802392A1 (es) 1985-04-04 1987-01-14 Un procedimiento para preparar nuevos esteres de acido androstano-17b-carboxilico
DD87305598A DD261364A5 (de) 1985-04-04 1987-07-31 Verfahren zur herstellung von ausgangsverbindungen fuer glucocorticosteroiden, die in der humanmedizin und veterinaermedizin angewendet werden kann
PH35610A PH23547A (en) 1985-04-04 1987-07-31 Process for the preparation of 16,17-acetal-substituted androstane-17b-barbocylic acid esters
NO873567A NO167294C (no) 1985-04-04 1987-08-24 Fremgangsmaate for fremstilling av 16,17-acetal-substituerte steroider.
MYPI87001991A MY102056A (en) 1985-04-04 1987-09-28 Novel 16, 17-acetalsubstituted androstane-17b- carboxylic acid esters
CS883736A CS268550B2 (en) 1985-04-04 1988-05-31 Method of new steroids production
PH37057A PH24369A (en) 1985-04-04 1988-06-13 Novel 16,17-acetalsubstituted androstane-17b-carboxylic acid esters,pharmaceutical compositions containing said compounds and method of use thereof
CA000589467A CA1334845C (en) 1985-04-04 1989-01-27 16,17-acetalsubstituted androstane-17.beta.-carboxylic acid esters
FI910379A FI105404B (sv) 1985-04-04 1991-01-25 Förfarande för framställning av 16,17-acetalsubstituerade androstanderivat
SU915001895A RU2081879C1 (ru) 1985-04-04 1991-11-05 Сложные эфиры 16 альфа 17 альфа - ацетальзамещенной андростан-17 бета - карбоновой кислоты или их стереоизомеры
CN91110725A CN1060471A (zh) 1985-04-04 1991-11-06 新的16，17-缩醛取代雄甾烷-17β-酮类的制备方法
DK059392A DK167150B1 (da) 1985-04-04 1992-05-05 16,17-acetalsubstituerede androstan-17beta-carboxylsyrer
DK059693A DK167574B1 (da) 1985-04-04 1993-05-21 Fremgangsmaade til fremstilling af en 16,17-acetalsubstitueret androstan-17beta-(2-oxoethylenoxy)-forbindelse
LVP-93-861A LV10281B (en) 1985-04-04 1993-06-30 Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
LVP-93-818A LV10960B (en) 1985-04-04 1993-06-30 Process for preparation of intermediate products
LVP-93-1006A LV10957B (en) 1985-04-04 1993-07-30 16 alpha, 17alpha-acetalsubstituted androstan-17betha-carboxyl acid esters, method of their preparation, intermediates, method of their producing, pharmaceutical compositions
LTIP1677A LT3812B (en) 1985-04-04 1993-12-28 Process for preparing intermediates of 3-okso-androstan-1,4dien-17beta-carboxylic acid
LTIP1678A LT3913B (en) 1985-04-04 1993-12-28 Novel 16,17-acetal-substituted androstan-17beta-carboxylic acid esters
LTIP1676A LT3811B (en) 1985-04-04 1993-12-28 Novel 16,17-acetal-substituted androstan-17beta-carboxylic acid esters, process for preparing thereof, pharmaceutical preparations
HK7197A HK7197A (en) 1985-04-04 1997-01-16 Process for the preparation of intermediates for 11-beta, 16-alpha, 17-alpha, 21-tetra-hydroxypregna-3, 20-dione 16-alpha, 17-alpha-acetals and 21-esters thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8501693A SE8501693D0 (sv) 1985-04-04 1985-04-04 Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters

Publications (1)

Publication Number Publication Date
SE8501693D0 true SE8501693D0 (sv) 1985-04-04

Family

ID=20359775

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8501693A SE8501693D0 (sv) 1985-04-04 1985-04-04 Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters

Country Status (31)

Country Link
US (1) US4950659A (ru)
EP (2) EP0197018B1 (ru)
JP (1) JPH0762028B2 (ru)
KR (1) KR930009444B1 (ru)
CN (1) CN1021444C (ru)
AT (2) ATE107657T1 (ru)
AU (1) AU590545B2 (ru)
CA (1) CA1333597C (ru)
CS (1) CS266581B2 (ru)
DD (2) DD247681A5 (ru)
DE (2) DE3687239T2 (ru)
DK (3) DK165638C (ru)
ES (2) ES8800264A1 (ru)
FI (1) FI85378C (ru)
GR (1) GR860902B (ru)
HU (2) HU196830B (ru)
IE (1) IE61474B1 (ru)
IL (1) IL78143A0 (ru)
JO (1) JO1479B1 (ru)
LT (3) LT3913B (ru)
LV (3) LV10281B (ru)
MY (1) MY102056A (ru)
NO (1) NO165298C (ru)
NZ (1) NZ215586A (ru)
PH (2) PH23547A (ru)
PL (2) PL148272B1 (ru)
PT (1) PT82340B (ru)
RU (3) RU1795972C (ru)
SE (1) SE8501693D0 (ru)
UA (2) UA19288A (ru)
ZA (1) ZA861884B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8501693D0 (sv) 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
HU203769B (en) * 1989-03-09 1991-09-30 Richter Gedeon Vegyeszet Process for producing new steroide derivatives and pharmaceutical compositions containing them
AU672669B2 (en) * 1992-12-24 1996-10-10 Rhone-Poulenc Rorer Limited New steroids
GB9423919D0 (en) * 1994-11-26 1995-01-11 Rhone Poulenc Rorer Ltd Chemical process
GB0110411D0 (en) * 2001-04-27 2001-06-20 Astrazeneca Ab Chemical process

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3828080A (en) * 1972-01-20 1974-08-06 Glaxo Lab Ltd Androstane-17beta-carboxylic acids and processes for the preparation thereof
SE378109B (ru) * 1972-05-19 1975-08-18 Bofors Ab
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
GB1517278A (en) * 1974-08-30 1978-07-12 Glaxo Lab Ltd Alkyl and haloalkyl androsta-1,4,15-triene and-4,15-diene-17beta-carboxylates
CH628355A5 (de) * 1976-02-24 1982-02-26 Ciba Geigy Ag Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.
US4198336A (en) * 1978-04-05 1980-04-15 Syntex (U.S.A.) Inc. Chemical process for preparing androsta-4-ene 17α-carboxylic acids
SE449106B (sv) * 1980-07-10 1987-04-06 Otsuka Pharma Co Ltd Steroid med anti-inflammatorisk verkan samt komposition innehallande denna
ZA814440B (en) * 1980-07-10 1982-10-27 Otsuka Pharma Co Ltd Soft steroids having anti-inflammatory activity
ZA817929B (en) * 1980-12-22 1982-10-27 Upjohn Co 5alpha-and 5beta-androstane-17beta-carboxylates
SE8306370D0 (sv) * 1983-11-18 1983-11-18 Draco Ab Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters
SE8501693D0 (sv) 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
JP2687768B2 (ja) * 1991-07-30 1997-12-08 トヨタ自動車株式会社 エンジンの制御装置

Also Published As

Publication number Publication date
DE3687239D1 (de) 1993-01-21
CN1021444C (zh) 1993-06-30
UA13319A (uk) 1997-02-28
RU2081879C1 (ru) 1997-06-20
JPS61236794A (ja) 1986-10-22
CS266581B2 (en) 1990-01-12
LV10957A (lv) 1995-12-20
LV10281B (en) 1995-04-20
KR930009444B1 (ko) 1993-10-04
DE3689936D1 (de) 1994-07-28
DK59392D0 (da) 1992-05-05
DK59392A (da) 1992-05-05
DK167574B1 (da) 1993-11-22
IE61474B1 (en) 1994-11-02
DK138386D0 (da) 1986-03-25
FI861275A0 (fi) 1986-03-25
CA1333597C (en) 1994-12-20
LTIP1677A (en) 1995-07-25
IL78143A0 (en) 1986-07-31
FI85378B (fi) 1991-12-31
RU1795972C (ru) 1993-02-15
DE3689936T2 (de) 1994-09-29
PL150052B1 (en) 1990-04-30
HUT40809A (en) 1987-02-27
DD247681A5 (de) 1987-07-15
EP0197018A1 (en) 1986-10-08
LTIP1678A (en) 1995-07-25
LT3812B (en) 1996-03-25
LV10957B (en) 1996-04-20
JPH0762028B2 (ja) 1995-07-05
PL148272B1 (en) 1989-09-30
UA19288A (ru) 1997-12-25
LV10960A (lv) 1995-12-20
MY102056A (en) 1992-03-31
DK138386A (da) 1986-10-05
NZ215586A (en) 1990-01-29
PT82340B (pt) 1988-10-14
AU5486886A (en) 1986-10-16
ES557314A0 (es) 1988-05-16
FI861275A (fi) 1986-10-05
GR860902B (en) 1986-07-29
EP0355859A1 (en) 1990-02-28
LV10281A (lv) 1994-10-20
AU590545B2 (en) 1989-11-09
NO165298B (no) 1990-10-15
FI85378C (fi) 1992-04-10
RU1779257C (ru) 1992-11-30
LV10960B (en) 1996-08-20
LTIP1676A (en) 1995-07-25
CS232886A2 (en) 1989-04-14
HU196830B (en) 1989-01-30
ES8800264A1 (es) 1987-10-16
NO861313L (no) 1986-10-06
ATE83241T1 (de) 1992-12-15
EP0355859B1 (en) 1994-06-22
DK59693A (da) 1993-05-21
DK165638C (da) 1993-06-01
PL265699A1 (en) 1988-03-03
DE3687239T2 (de) 1993-04-15
DK167150B1 (da) 1993-09-06
DK165638B (da) 1992-12-28
PT82340A (en) 1986-05-01
JO1479B1 (en) 1988-03-10
KR860008208A (ko) 1986-11-14
PH24369A (en) 1990-06-13
EP0197018B1 (en) 1992-12-09
LT3913B (en) 1996-04-25
NO165298C (no) 1991-01-23
ZA861884B (en) 1987-07-29
ATE107657T1 (de) 1994-07-15
DK59693D0 (da) 1993-05-21
US4950659A (en) 1990-08-21
ES8802392A1 (es) 1988-05-16
ES553675A0 (es) 1987-10-16
IE860879L (en) 1986-10-04
PH23547A (en) 1989-08-25
DD261364A5 (de) 1988-10-26
HU199872B (en) 1990-03-28
CN86102193A (zh) 1987-09-02
LT3811B (en) 1996-03-25

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