ATE83241T1 - 16,17-acetal-substituierte androstane-17-betacarbons|ureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten. - Google Patents

16,17-acetal-substituierte androstane-17-betacarbons|ureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten.

Info

Publication number
ATE83241T1
ATE83241T1 AT86850103T AT86850103T ATE83241T1 AT E83241 T1 ATE83241 T1 AT E83241T1 AT 86850103 T AT86850103 T AT 86850103T AT 86850103 T AT86850103 T AT 86850103T AT E83241 T1 ATE83241 T1 AT E83241T1
Authority
AT
Austria
Prior art keywords
sub
hydrogen
straight
compounds
carbon atoms
Prior art date
Application number
AT86850103T
Other languages
English (en)
Inventor
Paul Hakan Andersson
Per Ture Andersson
Bengt Ingemar Axelsson
Bror Arne Thalen
Jan William Trofast
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Application granted granted Critical
Publication of ATE83241T1 publication Critical patent/ATE83241T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrrole Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Threshing Machine Elements (AREA)
AT86850103T 1985-04-04 1986-03-21 16,17-acetal-substituierte androstane-17-betacarbons|ureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten. ATE83241T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8501693A SE8501693D0 (sv) 1985-04-04 1985-04-04 Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
EP86850103A EP0197018B1 (de) 1985-04-04 1986-03-21 16,17-Acetal-substituierte Androstane-17-beta-carbonsäureester, Verfahren zu deren Herstellung und pharmazeutische Präparate die diese enthalten

Publications (1)

Publication Number Publication Date
ATE83241T1 true ATE83241T1 (de) 1992-12-15

Family

ID=20359775

Family Applications (2)

Application Number Title Priority Date Filing Date
AT89116726T ATE107657T1 (de) 1985-04-04 1986-03-21 Verfahren zur herstellung von zwischenprodukten für 11-beta,16-alpha,17-alpha,21- tetrahydroxypregna-3-20-dione 16-alpha,17-alpha- acetal und deren 21-ester.
AT86850103T ATE83241T1 (de) 1985-04-04 1986-03-21 16,17-acetal-substituierte androstane-17-betacarbons|ureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT89116726T ATE107657T1 (de) 1985-04-04 1986-03-21 Verfahren zur herstellung von zwischenprodukten für 11-beta,16-alpha,17-alpha,21- tetrahydroxypregna-3-20-dione 16-alpha,17-alpha- acetal und deren 21-ester.

Country Status (31)

Country Link
US (1) US4950659A (de)
EP (2) EP0197018B1 (de)
JP (1) JPH0762028B2 (de)
KR (1) KR930009444B1 (de)
CN (1) CN1021444C (de)
AT (2) ATE107657T1 (de)
AU (1) AU590545B2 (de)
CA (1) CA1333597C (de)
CS (1) CS266581B2 (de)
DD (2) DD247681A5 (de)
DE (2) DE3689936T2 (de)
DK (3) DK165638C (de)
ES (2) ES8800264A1 (de)
FI (1) FI85378C (de)
GR (1) GR860902B (de)
HU (2) HU199872B (de)
IE (1) IE61474B1 (de)
IL (1) IL78143A0 (de)
JO (1) JO1479B1 (de)
LT (3) LT3913B (de)
LV (3) LV10960B (de)
MY (1) MY102056A (de)
NO (1) NO165298C (de)
NZ (1) NZ215586A (de)
PH (2) PH23547A (de)
PL (2) PL148272B1 (de)
PT (1) PT82340B (de)
RU (3) RU1795972C (de)
SE (1) SE8501693D0 (de)
UA (2) UA19288A (de)
ZA (1) ZA861884B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8501693D0 (sv) 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
HU203769B (en) * 1989-03-09 1991-09-30 Richter Gedeon Vegyeszet Process for producing new steroide derivatives and pharmaceutical compositions containing them
CA2149777C (en) * 1992-12-24 2004-05-25 Michael John Ashton New steroids
GB9423919D0 (en) * 1994-11-26 1995-01-11 Rhone Poulenc Rorer Ltd Chemical process
GB0110411D0 (en) * 2001-04-27 2001-06-20 Astrazeneca Ab Chemical process

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3828080A (en) * 1972-01-20 1974-08-06 Glaxo Lab Ltd Androstane-17beta-carboxylic acids and processes for the preparation thereof
SE378109B (de) * 1972-05-19 1975-08-18 Bofors Ab
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
GB1517278A (en) * 1974-08-30 1978-07-12 Glaxo Lab Ltd Alkyl and haloalkyl androsta-1,4,15-triene and-4,15-diene-17beta-carboxylates
CH628355A5 (de) * 1976-02-24 1982-02-26 Ciba Geigy Ag Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.
US4198336A (en) 1978-04-05 1980-04-15 Syntex (U.S.A.) Inc. Chemical process for preparing androsta-4-ene 17α-carboxylic acids
SE449106B (sv) * 1980-07-10 1987-04-06 Otsuka Pharma Co Ltd Steroid med anti-inflammatorisk verkan samt komposition innehallande denna
ZA814440B (en) * 1980-07-10 1982-10-27 Otsuka Pharma Co Ltd Soft steroids having anti-inflammatory activity
ZA817929B (en) * 1980-12-22 1982-10-27 Upjohn Co 5alpha-and 5beta-androstane-17beta-carboxylates
SE8306370D0 (sv) * 1983-11-18 1983-11-18 Draco Ab Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters
SE8501693D0 (sv) 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
JP2687768B2 (ja) * 1991-07-30 1997-12-08 トヨタ自動車株式会社 エンジンの制御装置

Also Published As

Publication number Publication date
DK138386A (da) 1986-10-05
JPH0762028B2 (ja) 1995-07-05
PL265699A1 (en) 1988-03-03
PH23547A (en) 1989-08-25
PL150052B1 (en) 1990-04-30
NO165298B (no) 1990-10-15
IL78143A0 (en) 1986-07-31
DK59693D0 (da) 1993-05-21
LT3812B (en) 1996-03-25
JO1479B1 (en) 1988-03-10
NZ215586A (en) 1990-01-29
RU1795972C (ru) 1993-02-15
LV10960A (lv) 1995-12-20
PT82340B (pt) 1988-10-14
IE860879L (en) 1986-10-04
EP0197018B1 (de) 1992-12-09
DK59693A (da) 1993-05-21
DD247681A5 (de) 1987-07-15
FI85378B (fi) 1991-12-31
ES553675A0 (es) 1987-10-16
NO861313L (no) 1986-10-06
ES557314A0 (es) 1988-05-16
HU199872B (en) 1990-03-28
SE8501693D0 (sv) 1985-04-04
UA19288A (uk) 1997-12-25
DE3687239T2 (de) 1993-04-15
HU196830B (en) 1989-01-30
LT3913B (en) 1996-04-25
DK165638C (da) 1993-06-01
CS266581B2 (en) 1990-01-12
ZA861884B (en) 1987-07-29
JPS61236794A (ja) 1986-10-22
PH24369A (en) 1990-06-13
EP0355859B1 (de) 1994-06-22
KR930009444B1 (ko) 1993-10-04
EP0355859A1 (de) 1990-02-28
US4950659A (en) 1990-08-21
DK165638B (da) 1992-12-28
DK138386D0 (da) 1986-03-25
LV10281B (en) 1995-04-20
RU1779257C (ru) 1992-11-30
DD261364A5 (de) 1988-10-26
DK59392D0 (da) 1992-05-05
LV10960B (en) 1996-08-20
CN1021444C (zh) 1993-06-30
LV10281A (lv) 1994-10-20
ATE107657T1 (de) 1994-07-15
DK167150B1 (da) 1993-09-06
ES8800264A1 (es) 1987-10-16
MY102056A (en) 1992-03-31
CA1333597C (en) 1994-12-20
FI861275A0 (fi) 1986-03-25
PL148272B1 (en) 1989-09-30
KR860008208A (ko) 1986-11-14
AU590545B2 (en) 1989-11-09
DE3687239D1 (de) 1993-01-21
CN86102193A (zh) 1987-09-02
LTIP1676A (en) 1995-07-25
CS232886A2 (en) 1989-04-14
HUT40809A (en) 1987-02-27
EP0197018A1 (de) 1986-10-08
AU5486886A (en) 1986-10-16
DK167574B1 (da) 1993-11-22
UA13319A (uk) 1997-02-28
DE3689936T2 (de) 1994-09-29
LV10957A (lv) 1995-12-20
DK59392A (da) 1992-05-05
LT3811B (en) 1996-03-25
ES8802392A1 (es) 1988-05-16
IE61474B1 (en) 1994-11-02
PT82340A (en) 1986-05-01
LTIP1678A (en) 1995-07-25
LV10957B (en) 1996-04-20
FI861275A (fi) 1986-10-05
GR860902B (en) 1986-07-29
FI85378C (fi) 1992-04-10
NO165298C (no) 1991-01-23
RU2081879C1 (ru) 1997-06-20
LTIP1677A (en) 1995-07-25
DE3689936D1 (de) 1994-07-28

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ATE83241T1 (de) 16,17-acetal-substituierte androstane-17-betacarbons|ureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten.
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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee