DE3687239D1 - 16,17-acetal-substituierte androstane-17-beta-carbonsaeureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten. - Google Patents

16,17-acetal-substituierte androstane-17-beta-carbonsaeureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten.

Info

Publication number
DE3687239D1
DE3687239D1 DE8686850103T DE3687239T DE3687239D1 DE 3687239 D1 DE3687239 D1 DE 3687239D1 DE 8686850103 T DE8686850103 T DE 8686850103T DE 3687239 T DE3687239 T DE 3687239T DE 3687239 D1 DE3687239 D1 DE 3687239D1
Authority
DE
Germany
Prior art keywords
sub
hydrogen
straight
compounds
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686850103T
Other languages
English (en)
Other versions
DE3687239T2 (de
Inventor
Paul Hakan Andersson
Per Ture Andersson
Bengt Ingemar Axelsson
Bror Arne Thalen
Jan William Trofast
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Draco AB
Original Assignee
Draco AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco AB filed Critical Draco AB
Application granted granted Critical
Publication of DE3687239D1 publication Critical patent/DE3687239D1/de
Publication of DE3687239T2 publication Critical patent/DE3687239T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fats And Perfumes (AREA)
  • Threshing Machine Elements (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
DE8686850103T 1985-04-04 1986-03-21 16,17-acetal-substituierte androstane-17-beta-carbonsaeureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten. Expired - Lifetime DE3687239T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8501693A SE8501693D0 (sv) 1985-04-04 1985-04-04 Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters

Publications (2)

Publication Number Publication Date
DE3687239D1 true DE3687239D1 (de) 1993-01-21
DE3687239T2 DE3687239T2 (de) 1993-04-15

Family

ID=20359775

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3689936T Expired - Lifetime DE3689936T2 (de) 1985-04-04 1986-03-21 Verfahren zur Herstellung von Zwischenprodukten für 11-beta,16-alpha,17-alpha,21-Tetrahydroxypregna-3-20-dione 16-alpha,17-alpha-Acetal und deren 21-Ester.
DE8686850103T Expired - Lifetime DE3687239T2 (de) 1985-04-04 1986-03-21 16,17-acetal-substituierte androstane-17-beta-carbonsaeureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE3689936T Expired - Lifetime DE3689936T2 (de) 1985-04-04 1986-03-21 Verfahren zur Herstellung von Zwischenprodukten für 11-beta,16-alpha,17-alpha,21-Tetrahydroxypregna-3-20-dione 16-alpha,17-alpha-Acetal und deren 21-Ester.

Country Status (31)

Country Link
US (1) US4950659A (de)
EP (2) EP0197018B1 (de)
JP (1) JPH0762028B2 (de)
KR (1) KR930009444B1 (de)
CN (1) CN1021444C (de)
AT (2) ATE83241T1 (de)
AU (1) AU590545B2 (de)
CA (1) CA1333597C (de)
CS (1) CS266581B2 (de)
DD (2) DD247681A5 (de)
DE (2) DE3689936T2 (de)
DK (3) DK165638C (de)
ES (2) ES8800264A1 (de)
FI (1) FI85378C (de)
GR (1) GR860902B (de)
HU (2) HU199872B (de)
IE (1) IE61474B1 (de)
IL (1) IL78143A0 (de)
JO (1) JO1479B1 (de)
LT (3) LT3812B (de)
LV (3) LV10281B (de)
MY (1) MY102056A (de)
NO (1) NO165298C (de)
NZ (1) NZ215586A (de)
PH (2) PH23547A (de)
PL (2) PL148272B1 (de)
PT (1) PT82340B (de)
RU (3) RU1795972C (de)
SE (1) SE8501693D0 (de)
UA (2) UA13319A (de)
ZA (1) ZA861884B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8501693D0 (sv) 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
HU203769B (en) * 1989-03-09 1991-09-30 Richter Gedeon Vegyeszet Process for producing new steroide derivatives and pharmaceutical compositions containing them
PL309402A1 (en) * 1992-12-24 1995-10-02 Rhone Poulenc Rorer Ltd Novel steroides
GB9423919D0 (en) * 1994-11-26 1995-01-11 Rhone Poulenc Rorer Ltd Chemical process
GB0110411D0 (en) * 2001-04-27 2001-06-20 Astrazeneca Ab Chemical process

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3828080A (en) * 1972-01-20 1974-08-06 Glaxo Lab Ltd Androstane-17beta-carboxylic acids and processes for the preparation thereof
SE378109B (de) * 1972-05-19 1975-08-18 Bofors Ab
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
GB1517278A (en) * 1974-08-30 1978-07-12 Glaxo Lab Ltd Alkyl and haloalkyl androsta-1,4,15-triene and-4,15-diene-17beta-carboxylates
CH628355A5 (de) * 1976-02-24 1982-02-26 Ciba Geigy Ag Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.
US4198336A (en) 1978-04-05 1980-04-15 Syntex (U.S.A.) Inc. Chemical process for preparing androsta-4-ene 17α-carboxylic acids
ZA814440B (en) * 1980-07-10 1982-10-27 Otsuka Pharma Co Ltd Soft steroids having anti-inflammatory activity
SE449106B (sv) * 1980-07-10 1987-04-06 Otsuka Pharma Co Ltd Steroid med anti-inflammatorisk verkan samt komposition innehallande denna
ZA817929B (en) * 1980-12-22 1982-10-27 Upjohn Co 5alpha-and 5beta-androstane-17beta-carboxylates
SE8306370D0 (sv) * 1983-11-18 1983-11-18 Draco Ab Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters
SE8501693D0 (sv) 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
JP2687768B2 (ja) * 1991-07-30 1997-12-08 トヨタ自動車株式会社 エンジンの制御装置

Also Published As

Publication number Publication date
ES8802392A1 (es) 1988-05-16
RU1779257C (ru) 1992-11-30
LV10281A (lv) 1994-10-20
CS266581B2 (en) 1990-01-12
CS232886A2 (en) 1989-04-14
FI85378C (fi) 1992-04-10
LV10957A (lv) 1995-12-20
LT3811B (en) 1996-03-25
PL150052B1 (en) 1990-04-30
LTIP1677A (en) 1995-07-25
NO165298C (no) 1991-01-23
LV10281B (en) 1995-04-20
DK167150B1 (da) 1993-09-06
LTIP1678A (en) 1995-07-25
DK138386A (da) 1986-10-05
LT3913B (en) 1996-04-25
ES8800264A1 (es) 1987-10-16
LV10957B (en) 1996-04-20
KR930009444B1 (ko) 1993-10-04
UA13319A (uk) 1997-02-28
HU196830B (en) 1989-01-30
ATE107657T1 (de) 1994-07-15
LT3812B (en) 1996-03-25
DK165638C (da) 1993-06-01
FI861275A0 (fi) 1986-03-25
AU5486886A (en) 1986-10-16
LV10960B (en) 1996-08-20
PL265699A1 (en) 1988-03-03
ES557314A0 (es) 1988-05-16
EP0197018A1 (de) 1986-10-08
PL148272B1 (en) 1989-09-30
LTIP1676A (en) 1995-07-25
DD247681A5 (de) 1987-07-15
EP0355859A1 (de) 1990-02-28
DE3689936T2 (de) 1994-09-29
ATE83241T1 (de) 1992-12-15
DK59693A (da) 1993-05-21
CN86102193A (zh) 1987-09-02
UA19288A (uk) 1997-12-25
DE3689936D1 (de) 1994-07-28
EP0355859B1 (de) 1994-06-22
SE8501693D0 (sv) 1985-04-04
DK59392A (da) 1992-05-05
DD261364A5 (de) 1988-10-26
IL78143A0 (en) 1986-07-31
NO861313L (no) 1986-10-06
DK165638B (da) 1992-12-28
FI861275A (fi) 1986-10-05
GR860902B (en) 1986-07-29
PT82340B (pt) 1988-10-14
JO1479B1 (en) 1988-03-10
DE3687239T2 (de) 1993-04-15
DK167574B1 (da) 1993-11-22
IE61474B1 (en) 1994-11-02
PH23547A (en) 1989-08-25
CN1021444C (zh) 1993-06-30
NZ215586A (en) 1990-01-29
KR860008208A (ko) 1986-11-14
LV10960A (lv) 1995-12-20
DK59693D0 (da) 1993-05-21
ES553675A0 (es) 1987-10-16
HU199872B (en) 1990-03-28
JPS61236794A (ja) 1986-10-22
ZA861884B (en) 1987-07-29
JPH0762028B2 (ja) 1995-07-05
RU1795972C (ru) 1993-02-15
CA1333597C (en) 1994-12-20
PH24369A (en) 1990-06-13
MY102056A (en) 1992-03-31
HUT40809A (en) 1987-02-27
PT82340A (en) 1986-05-01
RU2081879C1 (ru) 1997-06-20
US4950659A (en) 1990-08-21
FI85378B (fi) 1991-12-31
EP0197018B1 (de) 1992-12-09
DK138386D0 (da) 1986-03-25
AU590545B2 (en) 1989-11-09
IE860879L (en) 1986-10-04
DK59392D0 (da) 1992-05-05
NO165298B (no) 1990-10-15

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DE3583872D1 (de) Dihydropyridin-derivate, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zusammensetzungen, und verfahren zur herstellung dieser zusammensetzungen.
MY102057A (en) Novel androstane-17b-carboxylic acid esters
DE3687239T2 (de) 16,17-acetal-substituierte androstane-17-beta-carbonsaeureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten.
BE900178A (fr) Urees et thio-urees anti-atherosclerotiques.
JO1478B1 (en) Legacy of the new androstan-17 beta carboxylic acid

Legal Events

Date Code Title Description
8364 No opposition during term of opposition