RU2095368C1 - Циклические пептиды или их фармацевтически приемлемые соли, способ их получения - Google Patents

Циклические пептиды или их фармацевтически приемлемые соли, способ их получения Download PDF

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Publication number
RU2095368C1
RU2095368C1 SU925053217A SU5053217A RU2095368C1 RU 2095368 C1 RU2095368 C1 RU 2095368C1 SU 925053217 A SU925053217 A SU 925053217A SU 5053217 A SU5053217 A SU 5053217A RU 2095368 C1 RU2095368 C1 RU 2095368C1
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RU
Russia
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lys
ala
asp
boc
mmol
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SU925053217A
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English (en)
Russian (ru)
Inventor
Роберт Болин Девид
О'Доннелл Маргарет
Original Assignee
Ф.Хоффманн-Ла Роше АГ
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/17—Vasoactive intestinal peptides; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SU925053217A 1991-10-11 1992-10-08 Циклические пептиды или их фармацевтически приемлемые соли, способ их получения RU2095368C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77374791A 1991-10-11 1991-10-11
US737747 1991-10-11

Publications (1)

Publication Number Publication Date
RU2095368C1 true RU2095368C1 (ru) 1997-11-10

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
SU925053217A RU2095368C1 (ru) 1991-10-11 1992-10-08 Циклические пептиды или их фармацевтически приемлемые соли, способ их получения

Country Status (26)

Country Link
US (1) US5677419A (enExample)
EP (1) EP0536741B1 (enExample)
JP (1) JP2515473B2 (enExample)
KR (1) KR970001580B1 (enExample)
CN (3) CN1034943C (enExample)
AT (1) ATE132165T1 (enExample)
AU (1) AU656230B2 (enExample)
BG (1) BG61125B2 (enExample)
BR (1) BR9203959A (enExample)
CA (1) CA2080272C (enExample)
CZ (1) CZ281818B6 (enExample)
DE (1) DE69207138T2 (enExample)
DK (1) DK0536741T3 (enExample)
ES (1) ES2082317T3 (enExample)
FI (2) FI111646B (enExample)
GR (1) GR3019326T3 (enExample)
HU (2) HUT62606A (enExample)
IL (3) IL117252A (enExample)
MX (1) MX9205822A (enExample)
NO (3) NO304523B1 (enExample)
NZ (1) NZ244644A (enExample)
RU (1) RU2095368C1 (enExample)
SK (1) SK279399B6 (enExample)
TW (1) TW305846B (enExample)
UY (2) UY23488A1 (enExample)
ZA (1) ZA927724B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2304146C2 (ru) * 2005-10-17 2007-08-10 Закрытое акционерное общество "Эпитек" Способ стабилизации петлеобразной структуры синтетических пептидов с помощью n- и c-концевых модификаций
US11066446B2 (en) 2016-09-30 2021-07-20 Fujifilm Corporation Cyclic peptide, affinity chromatography support, labeled antibody, antibody drug conjugate, and pharmaceutical preparation

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872803B1 (en) 1993-09-21 2005-03-29 Kyowa Hakko Kogyo Co., Ltd. Peptides
WO1997029126A1 (en) * 1996-02-09 1997-08-14 F. Hoffmann-La Roche Ag Synthesis of vip analog
JP3647881B2 (ja) * 1996-07-12 2005-05-18 イムノメディクス，インコーポレイテッド 放射性金属元素結合ペプチドの類似化合物
WO1998002453A2 (en) * 1996-07-15 1998-01-22 Universite Libre De Bruxelles Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor
US6972319B1 (en) 1999-09-28 2005-12-06 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use
RU2269354C2 (ru) * 1999-09-28 2006-02-10 Байер Корпорейшн Агонисты рецептора-3(r3) пептида-активатора гипофизарной аденилатциклазы(расар) и способы их фармакологического применения
EP1257576B1 (en) 2000-02-18 2004-09-15 Dabur Research Foundation Vasoactive intestinal peptide analogs
AU2000263935A1 (en) 2000-02-18 2001-08-27 Dabur Research Foundation Radiolabeled vasoactive intestinal peptide analogs for diagnosis and radiotherapy
US6828304B1 (en) 2000-07-31 2004-12-07 Dabur Research Foundation Peptides for treatment of cancer
US7507714B2 (en) * 2000-09-27 2009-03-24 Bayer Corporation Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
AU2072002A (en) 2000-11-28 2002-06-11 Mondobiotech Sa Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension
CA2488358A1 (en) 2002-06-10 2003-12-18 Mondobiotech Laboratories Anstalt Use of compounds having the biological activity of vasoactive intestinal peptide for the treatment of sarcoidosis
EP1713493A4 (en) * 2004-01-27 2009-06-24 Bayer Pharmaceuticals Corp PEPTIDE-RECEPTOR (VPAC2) AGONISTS THAT ACTIVATE HYPOPHYSIC ADENYLATE CYCLASE (PACAP) AND PHARMACOLOGICAL METHODS OF USING THESE AGONISTS
CA2577326A1 (en) * 2004-08-18 2006-03-02 Eli Lilly & Company Selective vpac2 receptor peptide agonists
US20080085860A1 (en) * 2004-08-18 2008-04-10 Eli Lilly And Company Selective Vpac2 Receptor Peptide Agonists
US20100048460A1 (en) * 2006-02-28 2010-02-25 Lianshan Zhang Selective vpac2 receptor peptide agonists
JP2009542593A (ja) * 2006-07-06 2009-12-03 エフ．ホフマン−ラ ロシュ アーゲー 血管作動性腸管ペプチドの類似体
CN101906144B (zh) * 2009-06-03 2013-06-19 首都医科大学 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
WO2011020091A1 (en) 2009-08-14 2011-02-17 Phasebio Pharmaceuticals, Inc. Modified vasoactive intestinal peptides
US9782454B2 (en) * 2010-04-22 2017-10-10 Longevity Biotech, Inc. Highly active polypeptides and methods of making and using the same
EP2717902B1 (en) 2011-06-06 2018-01-24 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
WO2014145718A2 (en) 2013-03-15 2014-09-18 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
GB201421647D0 (en) * 2014-12-05 2015-01-21 Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
CA2976038A1 (en) 2015-02-09 2016-08-18 Phasebio Pharmaceuticals, Inc. Methods and compositions for treating muscle disease and disorders
TW202140513A (zh) * 2020-02-22 2021-11-01 日商Ｊｃｒ製藥股份有限公司 人類運鐵蛋白受體結合肽

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GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
US4835252A (en) * 1987-02-26 1989-05-30 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
GB8729802D0 (en) * 1987-12-22 1988-02-03 Beecham Group Plc Novel compounds
US5084442A (en) * 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5141924A (en) * 1989-06-30 1992-08-25 Hoffmann-La Roche, Inc. Synthetic vasoactive intestinal peptide analogs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DE, патент, 3915361, кл.C 07K 7/64, 1990. Merrifield R.B. J. Amer.chem. Soc, 1963, 85, 2144 - 2154. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2304146C2 (ru) * 2005-10-17 2007-08-10 Закрытое акционерное общество "Эпитек" Способ стабилизации петлеобразной структуры синтетических пептидов с помощью n- и c-концевых модификаций
US11066446B2 (en) 2016-09-30 2021-07-20 Fujifilm Corporation Cyclic peptide, affinity chromatography support, labeled antibody, antibody drug conjugate, and pharmaceutical preparation

Also Published As

Publication number Publication date
HUT62606A (en) 1993-05-28
FI111646B (fi) 2003-08-29
AU2622892A (en) 1993-04-22
GR3019326T3 (en) 1996-06-30
CZ308692A3 (en) 1993-08-11
IL103396A0 (en) 1993-03-15
NO923929L (no) 1993-04-13
KR970001580B1 (ko) 1997-02-11
DE69207138T2 (de) 1996-06-13
ES2082317T3 (es) 1996-03-16
CN1072415A (zh) 1993-05-26
EP0536741A2 (en) 1993-04-14
ATE132165T1 (de) 1996-01-15
TW305846B (enExample) 1997-05-21
JPH05213996A (ja) 1993-08-24
BG61125B2 (bg) 1996-11-29
NO975023D0 (no) 1997-10-31
KR930007972A (ko) 1993-05-20
CA2080272A1 (en) 1993-04-12
CN1198841C (zh) 2005-04-27
FI924580A0 (fi) 1992-10-09
IL117252A0 (en) 1996-06-18
AU656230B2 (en) 1995-01-27
CN1225473C (zh) 2005-11-02
SK279399B6 (sk) 1998-11-04
UY25084A1 (es) 1998-12-21
CZ281818B6 (cs) 1997-02-12
FI20002041A7 (fi) 2000-09-15
HU9203194D0 (en) 1992-12-28
JP2515473B2 (ja) 1996-07-10
CN1153785A (zh) 1997-07-09
DE69207138D1 (de) 1996-02-08
FI924580L (fi) 1993-04-12
FI20002041L (fi) 2000-09-15
ZA927724B (en) 1994-04-07
NO923929D0 (no) 1992-10-09
HU211534A9 (en) 1995-12-28
DK0536741T3 (da) 1996-04-22
NZ244644A (en) 1995-04-27
EP0536741A3 (enExample) 1994-04-06
IL117252A (en) 1999-11-30
NO980377D0 (no) 1998-01-28
CN1152579A (zh) 1997-06-25
IL103396A (en) 1997-11-20
CA2080272C (en) 2002-09-17
BR9203959A (pt) 1993-04-27
NO980377L (no) 1993-04-13
MX9205822A (es) 1993-06-01
NO975023L (no) 1993-04-13
SK308692A3 (en) 1995-03-08
EP0536741B1 (en) 1995-12-27
US5677419A (en) 1997-10-14
CN1034943C (zh) 1997-05-21
NO304523B1 (no) 1999-01-04
UY23488A1 (es) 1993-04-20

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