ATE132165T1 - Zyklische vip-analoge - Google Patents

Zyklische vip-analoge

Info

Publication number
ATE132165T1
ATE132165T1 AT92117185T AT92117185T ATE132165T1 AT E132165 T1 ATE132165 T1 AT E132165T1 AT 92117185 T AT92117185 T AT 92117185T AT 92117185 T AT92117185 T AT 92117185T AT E132165 T1 ATE132165 T1 AT E132165T1
Authority
AT
Austria
Prior art keywords
peptide
amino acid
vasoactive
chain
cyclic
Prior art date
Application number
AT92117185T
Other languages
German (de)
English (en)
Inventor
David Robert Bolin
Margaret O'donnell
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE132165T1 publication Critical patent/ATE132165T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/17—Vasoactive intestinal peptides; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT92117185T 1991-10-11 1992-10-08 Zyklische vip-analoge ATE132165T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77374791A 1991-10-11 1991-10-11

Publications (1)

Publication Number Publication Date
ATE132165T1 true ATE132165T1 (de) 1996-01-15

Family

ID=25099195

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92117185T ATE132165T1 (de) 1991-10-11 1992-10-08 Zyklische vip-analoge

Country Status (26)

Country Link
US (1) US5677419A (enExample)
EP (1) EP0536741B1 (enExample)
JP (1) JP2515473B2 (enExample)
KR (1) KR970001580B1 (enExample)
CN (3) CN1034943C (enExample)
AT (1) ATE132165T1 (enExample)
AU (1) AU656230B2 (enExample)
BG (1) BG61125B2 (enExample)
BR (1) BR9203959A (enExample)
CA (1) CA2080272C (enExample)
CZ (1) CZ281818B6 (enExample)
DE (1) DE69207138T2 (enExample)
DK (1) DK0536741T3 (enExample)
ES (1) ES2082317T3 (enExample)
FI (2) FI111646B (enExample)
GR (1) GR3019326T3 (enExample)
HU (2) HUT62606A (enExample)
IL (3) IL103396A (enExample)
MX (1) MX9205822A (enExample)
NO (3) NO304523B1 (enExample)
NZ (1) NZ244644A (enExample)
RU (1) RU2095368C1 (enExample)
SK (1) SK279399B6 (enExample)
TW (1) TW305846B (enExample)
UY (2) UY23488A1 (enExample)
ZA (1) ZA927724B (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872803B1 (en) 1993-09-21 2005-03-29 Kyowa Hakko Kogyo Co., Ltd. Peptides
JP2000504676A (ja) * 1996-02-09 2000-04-18 エフ・ホフマン―ラ ロシュ アーゲー Ｖｉｐアナログの合成
ES2297862T3 (es) * 1996-07-12 2008-05-01 Immunomedics, Inc. Analogos de peptidos que se unen a radiometales.
WO1998002453A2 (en) * 1996-07-15 1998-01-22 Universite Libre De Bruxelles Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor
ES2307534T3 (es) * 1999-09-28 2008-12-01 Bayer Corporation Agonistas de receptores 3 (r3) del peptido activador de la adenilato ciclasa hipofisiaria (pacap) y sus metodos de uso farmacologicos.
US6972319B1 (en) 1999-09-28 2005-12-06 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use
CA2405714A1 (en) 2000-02-18 2001-08-23 Dabur Research Foundation Radiolabeled vasoactive intestinal peptide analogs for diagnosis and radiotherapy
US6489297B1 (en) 2000-02-18 2002-12-03 Dabur Research Foundation Vasoactive intestinal peptide analogs
US6828304B1 (en) 2000-07-31 2004-12-07 Dabur Research Foundation Peptides for treatment of cancer
US7507714B2 (en) * 2000-09-27 2009-03-24 Bayer Corporation Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
WO2002043746A2 (en) 2000-11-28 2002-06-06 Mondobiotech Sa Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension
DE60326723D1 (de) 2002-06-10 2009-04-30 Mondobiotech Licensing Out Ag Verwendung von zusammensetzungen mit der biologischen aktivität der vasoaktiven intestinalen peptide zur behandlung von sarcoidose
KR20070009554A (ko) * 2004-01-27 2007-01-18 바이엘 파마슈티칼스 코포레이션 뇌하수체 아데닐레이트 사이클라제 활성화 펩티드(ｐａｃａｐ) 수용체 (ｖｐａｃ２) 작용제 및 이의약리학적 사용 방법
WO2006023356A2 (en) * 2004-08-18 2006-03-02 Eli Lilly And Company Selective vpac2 receptor peptide agonists
US20080085860A1 (en) * 2004-08-18 2008-04-10 Eli Lilly And Company Selective Vpac2 Receptor Peptide Agonists
RU2304146C2 (ru) * 2005-10-17 2007-08-10 Закрытое акционерное общество "Эпитек" Способ стабилизации петлеобразной структуры синтетических пептидов с помощью n- и c-концевых модификаций
CA2638733A1 (en) * 2006-02-28 2007-09-07 Eli Lilly And Company Selective vpac2 receptor peptide agonists
KR20090027239A (ko) * 2006-07-06 2009-03-16 에프. 호프만-라 로슈 아게 혈관작용성 장 펩티드의 유사체
CN101906144B (zh) * 2009-06-03 2013-06-19 首都医科大学 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
CA2804755C (en) 2009-08-14 2018-06-05 Phasebio Pharmaceuticals, Inc. Modified vasoactive intestinal peptides
WO2011133948A2 (en) 2010-04-22 2011-10-27 Longevity Biotech, Inc. Highly active polypeptides and methods of making and using the same
EP2717902B1 (en) 2011-06-06 2018-01-24 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
US9789164B2 (en) 2013-03-15 2017-10-17 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
GB201421647D0 (en) * 2014-12-05 2015-01-21 Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
AU2016219513B2 (en) 2015-02-09 2021-09-30 Immunoforge Co., Ltd. Methods and compositions for treating muscle disease and disorders
CA3036768A1 (en) 2016-09-30 2018-04-05 Fujifilm Corporation Cyclic peptide, affinity chromatography support, labeled antibody, antibody drug conjugate, and pharmaceutical preparation
CN115151556A (zh) * 2020-02-22 2022-10-04 Jcr制药股份有限公司 人转铁蛋白受体结合肽

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
US4835252A (en) * 1987-02-26 1989-05-30 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
GB8729802D0 (en) * 1987-12-22 1988-02-03 Beecham Group Plc Novel compounds
US5084442A (en) * 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5141924A (en) * 1989-06-30 1992-08-25 Hoffmann-La Roche, Inc. Synthetic vasoactive intestinal peptide analogs

Also Published As

Publication number Publication date
IL103396A (en) 1997-11-20
FI20002041L (fi) 2000-09-15
SK308692A3 (en) 1995-03-08
DE69207138T2 (de) 1996-06-13
SK279399B6 (sk) 1998-11-04
ES2082317T3 (es) 1996-03-16
IL117252A0 (en) 1996-06-18
FI20002041A7 (fi) 2000-09-15
HU9203194D0 (en) 1992-12-28
CN1072415A (zh) 1993-05-26
AU656230B2 (en) 1995-01-27
UY25084A1 (es) 1998-12-21
NO923929L (no) 1993-04-13
NO975023D0 (no) 1997-10-31
MX9205822A (es) 1993-06-01
KR970001580B1 (ko) 1997-02-11
BR9203959A (pt) 1993-04-27
FI924580A0 (fi) 1992-10-09
AU2622892A (en) 1993-04-22
IL103396A0 (en) 1993-03-15
RU2095368C1 (ru) 1997-11-10
US5677419A (en) 1997-10-14
FI924580L (fi) 1993-04-12
CN1198841C (zh) 2005-04-27
IL117252A (en) 1999-11-30
TW305846B (enExample) 1997-05-21
CA2080272C (en) 2002-09-17
EP0536741A3 (enExample) 1994-04-06
CZ281818B6 (cs) 1997-02-12
DE69207138D1 (de) 1996-02-08
NO975023L (no) 1993-04-13
HUT62606A (en) 1993-05-28
GR3019326T3 (en) 1996-06-30
NO923929D0 (no) 1992-10-09
BG61125B2 (bg) 1996-11-29
HU211534A9 (en) 1995-12-28
UY23488A1 (es) 1993-04-20
EP0536741A2 (en) 1993-04-14
EP0536741B1 (en) 1995-12-27
CA2080272A1 (en) 1993-04-12
CN1153785A (zh) 1997-07-09
JPH05213996A (ja) 1993-08-24
NO980377L (no) 1993-04-13
FI111646B (fi) 2003-08-29
NZ244644A (en) 1995-04-27
NO304523B1 (no) 1999-01-04
ZA927724B (en) 1994-04-07
DK0536741T3 (da) 1996-04-22
CN1225473C (zh) 2005-11-02
CN1034943C (zh) 1997-05-21
NO980377D0 (no) 1998-01-28
CN1152579A (zh) 1997-06-25
CZ308692A3 (en) 1993-08-11
KR930007972A (ko) 1993-05-20
JP2515473B2 (ja) 1996-07-10

Similar Documents

Publication Publication Date Title
ATE132165T1 (de) Zyklische vip-analoge
IL142025A0 (en) Novel methods for displaying (poly) peptides/proteins on bacteriophage particles via disulfide bonds
EP0662827A4 (en) THERAPEUTIC AND DIAGNOSTIC METHODS AND COMPOSITIONS BASED ON NOTCH PROTEINS AND NUCLEIC ACIDS.
FR2744134B1 (fr) Proteines de reserve de plantes enrichies en acides amines, notamment alpha-zeine de mais enrichie en lysine plantes exprimant ces proteines
DK601786A (da) Hidtil ukendte prokoagulationsproteiner
NO950668D0 (no) Peptider avledet fra et retrovirus fra HIV-gruppen og anvendelser derav
ATE201696T1 (de) Zyklische peptidanaloga von somatostatin
NZ502993A (en) Treatment of obesity using hGH 177-191analogues
DE69827262D1 (de) Penaeidine: antimikrobielle peptide aus krebstieren
DE69220100D1 (de) Retrovirale Protease-Inhibitoren
FR2575163B1 (fr) Tri- et tetrapeptides reduits inhibiteurs de la secretion gastrique, procede d'obtention et compositions pharmaceutiques les contenant
ATE46173T1 (de) Pharmakologisch aktive peptide.
AU2003260306A1 (en) Bicyclic oligopeptides
MX9707904A (es) Analogos del factor de liberacion de la hormona del crecimiento.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee