UY23488A1 - Procedimiento para la preparacion de peptidos ciclicos vasoactivos - Google Patents
Procedimiento para la preparacion de peptidos ciclicos vasoactivosInfo
- Publication number
- UY23488A1 UY23488A1 UY23488A UY23488A UY23488A1 UY 23488 A1 UY23488 A1 UY 23488A1 UY 23488 A UY23488 A UY 23488A UY 23488 A UY23488 A UY 23488A UY 23488 A1 UY23488 A1 UY 23488A1
- Authority
- UY
- Uruguay
- Prior art keywords
- vasoactive
- cyclic peptides
- amino acid
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/17—Vasoactive intestinal peptides; related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La presente invención se refiere a los análogos del péptido vasoactivo (VIP), en los que el carboxilo terminal de la cadena lateral de un aminoácido se une covalentemente al amino terminal de la cadena lateral de otro aminoácido en la cadena peptídica por la vía de formación de un enlace amida. La unión covalente entre los dos restos de aminoácido de la cadena peptídica conduce a la formación de una estructura anular. La presente invención proporciona péptidos cíclicos vasoactivos de fórmula I y composiciones farmacéuticas que contienen dichos péptidos cíclicos vasoactivos, para el tratamiento de trastornos constrictivos broncotranqueales.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
UY25084A UY25084A1 (es) | 1991-10-11 | 1998-07-06 | Un procedimiento para la preparacion de una composicion farmaceutica |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77374791A | 1991-10-11 | 1991-10-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY23488A1 true UY23488A1 (es) | 1993-04-20 |
Family
ID=25099195
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY23488A UY23488A1 (es) | 1991-10-11 | 1992-10-09 | Procedimiento para la preparacion de peptidos ciclicos vasoactivos |
UY25084A UY25084A1 (es) | 1991-10-11 | 1998-07-06 | Un procedimiento para la preparacion de una composicion farmaceutica |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY25084A UY25084A1 (es) | 1991-10-11 | 1998-07-06 | Un procedimiento para la preparacion de una composicion farmaceutica |
Country Status (26)
Country | Link |
---|---|
US (1) | US5677419A (es) |
EP (1) | EP0536741B1 (es) |
JP (1) | JP2515473B2 (es) |
KR (1) | KR970001580B1 (es) |
CN (3) | CN1034943C (es) |
AT (1) | ATE132165T1 (es) |
AU (1) | AU656230B2 (es) |
BG (1) | BG61125B2 (es) |
BR (1) | BR9203959A (es) |
CA (1) | CA2080272C (es) |
CZ (1) | CZ281818B6 (es) |
DE (1) | DE69207138T2 (es) |
DK (1) | DK0536741T3 (es) |
ES (1) | ES2082317T3 (es) |
FI (2) | FI111646B (es) |
GR (1) | GR3019326T3 (es) |
HU (2) | HUT62606A (es) |
IL (3) | IL117252A (es) |
MX (1) | MX9205822A (es) |
NO (3) | NO304523B1 (es) |
NZ (1) | NZ244644A (es) |
RU (1) | RU2095368C1 (es) |
SK (1) | SK279399B6 (es) |
TW (1) | TW305846B (es) |
UY (2) | UY23488A1 (es) |
ZA (1) | ZA927724B (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6872803B1 (en) | 1993-09-21 | 2005-03-29 | Kyowa Hakko Kogyo Co., Ltd. | Peptides |
ATE328004T1 (de) * | 1996-02-09 | 2006-06-15 | Hoffmann La Roche | Herstellung eines vip-analogen |
JP3647881B2 (ja) | 1996-07-12 | 2005-05-18 | イムノメディクス,インコーポレイテッド | 放射性金属元素結合ペプチドの類似化合物 |
WO1998002453A2 (en) * | 1996-07-15 | 1998-01-22 | Universite Libre De Bruxelles | Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor |
US6972319B1 (en) | 1999-09-28 | 2005-12-06 | Bayer Pharmaceuticals Corporation | Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use |
WO2001023420A2 (en) * | 1999-09-28 | 2001-04-05 | Bayer Corporation | Pituitary adenylate cyclase activating peptide (pacap) receptor 3 (r3) agonists and their pharmacological methods of use |
US6489297B1 (en) | 2000-02-18 | 2002-12-03 | Dabur Research Foundation | Vasoactive intestinal peptide analogs |
CA2405714A1 (en) | 2000-02-18 | 2001-08-23 | Dabur Research Foundation | Radiolabeled vasoactive intestinal peptide analogs for diagnosis and radiotherapy |
US6828304B1 (en) | 2000-07-31 | 2004-12-07 | Dabur Research Foundation | Peptides for treatment of cancer |
US7507714B2 (en) * | 2000-09-27 | 2009-03-24 | Bayer Corporation | Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use |
CN101229363A (zh) | 2000-11-28 | 2008-07-30 | 蒙多生物技术许可股份公司 | 具有血管活性肠肽的生物学活性的用于治疗肺动脉和小动脉高压的化合物 |
CA2488358A1 (en) | 2002-06-10 | 2003-12-18 | Mondobiotech Laboratories Anstalt | Use of compounds having the biological activity of vasoactive intestinal peptide for the treatment of sarcoidosis |
US20090143283A1 (en) * | 2004-01-27 | 2009-06-04 | Bayer Pharmaceuticals Corporation | Pituitary Adenylate Cyclase Activating Peptide (PACAP) Receptor (VPAC2) Agonists and Their Pharmacological Methods of Use |
US20080085860A1 (en) * | 2004-08-18 | 2008-04-10 | Eli Lilly And Company | Selective Vpac2 Receptor Peptide Agonists |
CA2576755A1 (en) * | 2004-08-18 | 2006-03-02 | Eli Lilly And Company | Selective vpac2 receptor peptide agonists |
BRPI0708341A2 (pt) * | 2006-02-28 | 2011-05-24 | Lilly Co Eli | agonistas peptìdicos seletivos do receptor vpac2 |
CN101484468A (zh) * | 2006-07-06 | 2009-07-15 | 霍夫曼-拉罗奇有限公司 | 新型血管活性肠肽类似物 |
CN101906144B (zh) * | 2009-06-03 | 2013-06-19 | 首都医科大学 | 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用 |
PT3311828T (pt) | 2009-08-14 | 2021-05-05 | Phasebio Pharmaceuticals Inc | Péptidos intestinais vasoativos modificados |
US9782454B2 (en) * | 2010-04-22 | 2017-10-10 | Longevity Biotech, Inc. | Highly active polypeptides and methods of making and using the same |
WO2012170524A1 (en) | 2011-06-06 | 2012-12-13 | Phasebio Pharmaceuticals, Inc. | Use of modified vasoactive intestinal peptides in the treatment of hypertension |
EP2968469A4 (en) | 2013-03-15 | 2016-08-31 | Longevity Biotech Inc | PEPTIDES COMPRISING NON-ENDOGENIC AMINO ACIDS AND METHODS OF MAKING AND USING SAME |
GB201421647D0 (en) | 2014-12-05 | 2015-01-21 | Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie | CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases |
CN114652817A (zh) | 2015-02-09 | 2022-06-24 | 费斯生物制药公司 | 用于治疗肌肉疾病和病症的方法和组合物 |
EP4043479A1 (en) | 2016-09-30 | 2022-08-17 | FUJIFILM Corporation | Cyclic peptide, affinity chromatography support, labeled antibody, antibody-drug conjugate, and pharmaceutical preparation |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8427651D0 (en) * | 1984-11-01 | 1984-12-05 | Beecham Group Plc | Compounds |
US4835252A (en) * | 1987-02-26 | 1989-05-30 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Vasoactive intestinal peptide analogs |
GB8729802D0 (en) * | 1987-12-22 | 1988-02-03 | Beecham Group Plc | Novel compounds |
US5084442A (en) * | 1988-09-06 | 1992-01-28 | Hoffmann-La Roche Inc. | Cyclic growth hormone releasing factor analogs and method for the manufacture thereof |
US5141924A (en) * | 1989-06-30 | 1992-08-25 | Hoffmann-La Roche, Inc. | Synthetic vasoactive intestinal peptide analogs |
-
1992
- 1992-10-06 AU AU26228/92A patent/AU656230B2/en not_active Ceased
- 1992-10-07 NZ NZ244644A patent/NZ244644A/en unknown
- 1992-10-07 ZA ZA927724A patent/ZA927724B/xx unknown
- 1992-10-08 DK DK92117185.6T patent/DK0536741T3/da active
- 1992-10-08 RU SU925053217A patent/RU2095368C1/ru active
- 1992-10-08 EP EP92117185A patent/EP0536741B1/en not_active Expired - Lifetime
- 1992-10-08 ES ES92117185T patent/ES2082317T3/es not_active Expired - Lifetime
- 1992-10-08 TW TW081107995A patent/TW305846B/zh active
- 1992-10-08 AT AT92117185T patent/ATE132165T1/de not_active IP Right Cessation
- 1992-10-08 DE DE69207138T patent/DE69207138T2/de not_active Expired - Lifetime
- 1992-10-09 MX MX9205822A patent/MX9205822A/es not_active IP Right Cessation
- 1992-10-09 SK SK3086-92A patent/SK279399B6/sk unknown
- 1992-10-09 NO NO923929A patent/NO304523B1/no not_active IP Right Cessation
- 1992-10-09 UY UY23488A patent/UY23488A1/es not_active IP Right Cessation
- 1992-10-09 FI FI924580A patent/FI111646B/fi active
- 1992-10-09 IL IL11725292A patent/IL117252A/xx not_active IP Right Cessation
- 1992-10-09 IL IL103396A patent/IL103396A/xx not_active IP Right Cessation
- 1992-10-09 CZ CS923086A patent/CZ281818B6/cs not_active IP Right Cessation
- 1992-10-09 HU HU9203194A patent/HUT62606A/hu unknown
- 1992-10-09 CA CA002080272A patent/CA2080272C/en not_active Expired - Fee Related
- 1992-10-09 JP JP4297835A patent/JP2515473B2/ja not_active Expired - Fee Related
- 1992-10-10 KR KR1019920018660A patent/KR970001580B1/ko not_active IP Right Cessation
- 1992-10-10 CN CN92113069A patent/CN1034943C/zh not_active Expired - Fee Related
- 1992-10-13 BR BR929203959A patent/BR9203959A/pt not_active Application Discontinuation
-
1994
- 1994-02-28 BG BG98608A patent/BG61125B2/bg unknown
- 1994-09-19 US US08/308,729 patent/US5677419A/en not_active Expired - Lifetime
-
1995
- 1995-06-21 HU HU95P/P00297P patent/HU211534A9/hu unknown
-
1996
- 1996-02-23 IL IL11725296A patent/IL117252A0/xx unknown
- 1996-03-15 GR GR960400712T patent/GR3019326T3/el unknown
- 1996-08-15 CN CNB961118075A patent/CN1225473C/zh not_active Expired - Fee Related
- 1996-08-15 CN CNB961115238A patent/CN1198841C/zh not_active Expired - Fee Related
-
1997
- 1997-10-31 NO NO975023A patent/NO975023D0/no not_active Application Discontinuation
-
1998
- 1998-01-28 NO NO980377A patent/NO980377D0/no unknown
- 1998-07-06 UY UY25084A patent/UY25084A1/es unknown
-
2000
- 2000-09-15 FI FI20002041A patent/FI20002041A/fi unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
VENC | Patent expired |
Effective date: 20140115 |