NO980377L - Vasoaktive cykliske peptider - Google Patents

Vasoaktive cykliske peptider

Info

Publication number
NO980377L
NO980377L NO980377A NO980377A NO980377L NO 980377 L NO980377 L NO 980377L NO 980377 A NO980377 A NO 980377A NO 980377 A NO980377 A NO 980377A NO 980377 L NO980377 L NO 980377L
Authority
NO
Norway
Prior art keywords
vasoactive
amino acid
peptide
peptide chain
cyclic peptides
Prior art date
Application number
NO980377A
Other languages
English (en)
Other versions
NO980377D0 (no
Inventor
David Robert Bolin
Margaret O'donnel
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO980377L publication Critical patent/NO980377L/no
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO980377D0 publication Critical patent/NO980377D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/17—Vasoactive intestinal peptides; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Det er beskrevet vasoaktive peptidanaloger (VIP) hvor sidekjede-karboksylterminalen av en aminosyre i peptid- kj eden er bundet kovalent til sidekjedeaminoterminalen av en annen aminosyre i peptidkjeden via dannelsen av en amidbinding. Den kovalente binding mellom de to amino- syreresiduer i peptidkjeden gir en ringstruktur. Fore- liggende forbindelser gir cykliske vasoaktive peptider og farmasøytiske blandinger omfattende slike cykliske vasoaktive peptider for behandling av bronkotrakiale sammentrekningslidelser.
NO980377A 1991-10-11 1998-01-28 Vasoaktive cykliske peptider NO980377D0 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77374791A 1991-10-11 1991-10-11

Publications (2)

Publication Number Publication Date
NO980377L true NO980377L (no) 1993-04-13
NO980377D0 NO980377D0 (no) 1998-01-28

Family

ID=25099195

Family Applications (3)

Application Number Title Priority Date Filing Date
NO923929A NO304523B1 (no) 1991-10-11 1992-10-09 Vasoaktive cykliske polypeptider
NO975023A NO975023D0 (no) 1991-10-11 1997-10-31 Vasoaktive cykliske polypeptider
NO980377A NO980377D0 (no) 1991-10-11 1998-01-28 Vasoaktive cykliske peptider

Family Applications Before (2)

Application Number Title Priority Date Filing Date
NO923929A NO304523B1 (no) 1991-10-11 1992-10-09 Vasoaktive cykliske polypeptider
NO975023A NO975023D0 (no) 1991-10-11 1997-10-31 Vasoaktive cykliske polypeptider

Country Status (26)

Country Link
US (1) US5677419A (no)
EP (1) EP0536741B1 (no)
JP (1) JP2515473B2 (no)
KR (1) KR970001580B1 (no)
CN (3) CN1034943C (no)
AT (1) ATE132165T1 (no)
AU (1) AU656230B2 (no)
BG (1) BG61125B2 (no)
BR (1) BR9203959A (no)
CA (1) CA2080272C (no)
CZ (1) CZ281818B6 (no)
DE (1) DE69207138T2 (no)
DK (1) DK0536741T3 (no)
ES (1) ES2082317T3 (no)
FI (2) FI111646B (no)
GR (1) GR3019326T3 (no)
HU (2) HUT62606A (no)
IL (3) IL117252A (no)
MX (1) MX9205822A (no)
NO (3) NO304523B1 (no)
NZ (1) NZ244644A (no)
RU (1) RU2095368C1 (no)
SK (1) SK279399B6 (no)
TW (1) TW305846B (no)
UY (2) UY23488A1 (no)
ZA (1) ZA927724B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872803B1 (en) 1993-09-21 2005-03-29 Kyowa Hakko Kogyo Co., Ltd. Peptides
WO1997029126A1 (en) * 1996-02-09 1997-08-14 F. Hoffmann-La Roche Ag Synthesis of vip analog
AU725827B2 (en) * 1996-07-12 2000-10-19 Immunomedics Inc. Radiometal-binding peptide analogues
WO1998002453A2 (en) * 1996-07-15 1998-01-22 Universite Libre De Bruxelles Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor
PE20010612A1 (es) * 1999-09-28 2001-07-12 Bayer Corp Agonistas del receptor 3 (r3) del peptido activador de la adenilato ciclasa de la pituitaria y su uso farmacologico
US6972319B1 (en) 1999-09-28 2005-12-06 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use
AU2000265051A1 (en) * 2000-02-18 2001-08-27 Dabur Research Foundation Vasoactive intestinal peptide analogs
WO2001060863A1 (en) 2000-02-18 2001-08-23 Dabur Research Foundation Radiolabeled vasoactive intestinal peptide analogs for diagnosis and radiotherapy
US6828304B1 (en) 2000-07-31 2004-12-07 Dabur Research Foundation Peptides for treatment of cancer
US7507714B2 (en) * 2000-09-27 2009-03-24 Bayer Corporation Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
JP2004514697A (ja) 2000-11-28 2004-05-20 モンドバイオテック・ソシエテ・アノニム 肺及び細動脈高血圧症治療用の血管作動性腸管ペプチドの生物学的活性をもつ化合物
EP1515745B1 (en) 2002-06-10 2009-03-18 MondoBIOTECH Licensing Out AG Use of compounds having the biological activity of vasoactive intestinal peptide for the treatment of sarcoidosis
CA2554475A1 (en) * 2004-01-27 2005-08-11 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use
US20080085860A1 (en) * 2004-08-18 2008-04-10 Eli Lilly And Company Selective Vpac2 Receptor Peptide Agonists
CA2577010A1 (en) * 2004-08-18 2006-03-02 Eli Lilly And Company Selective vpac2 receptor peptide agonists
MX2008011048A (es) * 2006-02-28 2008-09-08 Lilly Co Eli Agonistas peptidicos del receptor vpac2 selectivo.
JP2009542593A (ja) * 2006-07-06 2009-12-03 エフ．ホフマン−ラ ロシュ アーゲー 血管作動性腸管ペプチドの類似体
CN101906144B (zh) * 2009-06-03 2013-06-19 首都医科大学 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
EP2464370B1 (en) 2009-08-14 2017-03-29 Phasebio Pharmaceuticals, Inc. Modified vasoactive intestinal peptides
CA2797033C (en) 2010-04-22 2021-10-19 Longevity Biotech, Inc. Highly active polypeptides and methods of making and using the same
CA2873553C (en) 2011-06-06 2020-01-28 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
US9789164B2 (en) 2013-03-15 2017-10-17 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
GB201421647D0 (en) 2014-12-05 2015-01-21 Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
US10688156B2 (en) 2015-02-09 2020-06-23 Phasebio Pharmaceuticals, Inc. Methods and compositions for treating muscle disease and disorders
KR102243870B1 (ko) 2016-09-30 2021-04-22 후지필름 가부시키가이샤 환상 펩타이드, 어피니티 크로마토그래피 담체, 표지화 항체, 항체 약물 복합체 및 의약 제제

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
US4835252A (en) * 1987-02-26 1989-05-30 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
GB8729802D0 (en) * 1987-12-22 1988-02-03 Beecham Group Plc Novel compounds
US5084442A (en) * 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5141924A (en) * 1989-06-30 1992-08-25 Hoffmann-La Roche, Inc. Synthetic vasoactive intestinal peptide analogs

Also Published As

Publication number Publication date
CN1152579A (zh) 1997-06-25
CN1034943C (zh) 1997-05-21
AU2622892A (en) 1993-04-22
DK0536741T3 (da) 1996-04-22
KR970001580B1 (ko) 1997-02-11
IL117252A0 (en) 1996-06-18
JPH05213996A (ja) 1993-08-24
NO975023D0 (no) 1997-10-31
UY23488A1 (es) 1993-04-20
AU656230B2 (en) 1995-01-27
FI20002041A (fi) 2000-09-15
MX9205822A (es) 1993-06-01
ATE132165T1 (de) 1996-01-15
CN1072415A (zh) 1993-05-26
NZ244644A (en) 1995-04-27
CN1225473C (zh) 2005-11-02
KR930007972A (ko) 1993-05-20
TW305846B (no) 1997-05-21
EP0536741A3 (no) 1994-04-06
NO975023L (no) 1993-04-13
IL117252A (en) 1999-11-30
DE69207138D1 (de) 1996-02-08
SK279399B6 (sk) 1998-11-04
EP0536741B1 (en) 1995-12-27
DE69207138T2 (de) 1996-06-13
GR3019326T3 (en) 1996-06-30
BR9203959A (pt) 1993-04-27
IL103396A0 (en) 1993-03-15
ES2082317T3 (es) 1996-03-16
ZA927724B (en) 1994-04-07
FI924580A (fi) 1993-04-12
UY25084A1 (es) 1998-12-21
US5677419A (en) 1997-10-14
JP2515473B2 (ja) 1996-07-10
CA2080272A1 (en) 1993-04-12
NO923929D0 (no) 1992-10-09
CA2080272C (en) 2002-09-17
BG61125B2 (bg) 1996-11-29
FI924580A0 (fi) 1992-10-09
HU211534A9 (en) 1995-12-28
IL103396A (en) 1997-11-20
NO980377D0 (no) 1998-01-28
RU2095368C1 (ru) 1997-11-10
CZ281818B6 (cs) 1997-02-12
CN1198841C (zh) 2005-04-27
HU9203194D0 (en) 1992-12-28
FI111646B (fi) 2003-08-29
CZ308692A3 (en) 1993-08-11
SK308692A3 (en) 1995-03-08
CN1153785A (zh) 1997-07-09
NO304523B1 (no) 1999-01-04
EP0536741A2 (en) 1993-04-14
NO923929L (no) 1993-04-13
HUT62606A (en) 1993-05-28

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