IL103396A - Cyclic derivatives of the vasoactive intestinal peptide, their preparation and pharmaceutical compositions containing them - Google Patents

Cyclic derivatives of the vasoactive intestinal peptide, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL103396A
IL103396A IL103396A IL10339692A IL103396A IL 103396 A IL103396 A IL 103396A IL 103396 A IL103396 A IL 103396A IL 10339692 A IL10339692 A IL 10339692A IL 103396 A IL103396 A IL 103396A
Authority
IL
Israel
Prior art keywords
peptide
pharmaceutical compositions
preparation
amino acid
compositions containing
Prior art date
Application number
IL103396A
Other languages
English (en)
Other versions
IL103396A0 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to IL11725292A priority Critical patent/IL117252A/xx
Publication of IL103396A0 publication Critical patent/IL103396A0/xx
Publication of IL103396A publication Critical patent/IL103396A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/17—Vasoactive intestinal peptides; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL103396A 1991-10-11 1992-10-09 Cyclic derivatives of the vasoactive intestinal peptide, their preparation and pharmaceutical compositions containing them IL103396A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL11725292A IL117252A (en) 1991-10-11 1992-10-09 Cyclic derivatives of the vasoactive intestinal peptide their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77374791A 1991-10-11 1991-10-11

Publications (2)

Publication Number Publication Date
IL103396A0 IL103396A0 (en) 1993-03-15
IL103396A true IL103396A (en) 1997-11-20

Family

ID=25099195

Family Applications (3)

Application Number Title Priority Date Filing Date
IL103396A IL103396A (en) 1991-10-11 1992-10-09 Cyclic derivatives of the vasoactive intestinal peptide, their preparation and pharmaceutical compositions containing them
IL11725292A IL117252A (en) 1991-10-11 1992-10-09 Cyclic derivatives of the vasoactive intestinal peptide their preparation and pharmaceutical compositions containing them
IL11725296A IL117252A0 (en) 1991-10-11 1996-02-23 Cyclic derivatives of the vasoactive intestinal peptide their preparation and pharmaceutical compositions containing them

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL11725292A IL117252A (en) 1991-10-11 1992-10-09 Cyclic derivatives of the vasoactive intestinal peptide their preparation and pharmaceutical compositions containing them
IL11725296A IL117252A0 (en) 1991-10-11 1996-02-23 Cyclic derivatives of the vasoactive intestinal peptide their preparation and pharmaceutical compositions containing them

Country Status (26)

Country Link
US (1) US5677419A (xx)
EP (1) EP0536741B1 (xx)
JP (1) JP2515473B2 (xx)
KR (1) KR970001580B1 (xx)
CN (3) CN1034943C (xx)
AT (1) ATE132165T1 (xx)
AU (1) AU656230B2 (xx)
BG (1) BG61125B2 (xx)
BR (1) BR9203959A (xx)
CA (1) CA2080272C (xx)
CZ (1) CZ281818B6 (xx)
DE (1) DE69207138T2 (xx)
DK (1) DK0536741T3 (xx)
ES (1) ES2082317T3 (xx)
FI (2) FI111646B (xx)
GR (1) GR3019326T3 (xx)
HU (2) HUT62606A (xx)
IL (3) IL103396A (xx)
MX (1) MX9205822A (xx)
NO (3) NO304523B1 (xx)
NZ (1) NZ244644A (xx)
RU (1) RU2095368C1 (xx)
SK (1) SK279399B6 (xx)
TW (1) TW305846B (xx)
UY (2) UY23488A1 (xx)
ZA (1) ZA927724B (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872803B1 (en) 1993-09-21 2005-03-29 Kyowa Hakko Kogyo Co., Ltd. Peptides
AU722895B2 (en) * 1996-02-09 2000-08-10 F. Hoffmann-La Roche Ag Synthesis of VIP analog
DE69738353T2 (de) 1996-07-12 2009-09-24 Immunomedics, Inc. Radiometall-bindende peptide analoge
WO1998002453A2 (en) * 1996-07-15 1998-01-22 Universite Libre De Bruxelles Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor
CA2379604A1 (en) * 1999-09-28 2001-04-05 Bayer Corporation Pituitary adenylate cyclase activating peptide (pacap) receptor 3 (r3) agonists and their pharmacological methods of use
US6972319B1 (en) 1999-09-28 2005-12-06 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use
AU2000263935A1 (en) 2000-02-18 2001-08-27 Dabur Research Foundation Radiolabeled vasoactive intestinal peptide analogs for diagnosis and radiotherapy
WO2001060862A1 (en) 2000-02-18 2001-08-23 Dabur Research Foundation Vasoactive intestinal peptide analogs
US6828304B1 (en) 2000-07-31 2004-12-07 Dabur Research Foundation Peptides for treatment of cancer
US7507714B2 (en) * 2000-09-27 2009-03-24 Bayer Corporation Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
WO2002043746A2 (en) 2000-11-28 2002-06-06 Mondobiotech Sa Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension
CN1313149C (zh) 2002-06-10 2007-05-02 蒙杜生物科技安斯塔特实验室 具有血管活性肠肽的生物学活性的化合物在治疗结节病中的用途
CA2554475A1 (en) * 2004-01-27 2005-08-11 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use
WO2006023358A1 (en) * 2004-08-18 2006-03-02 Eli Lilly And Company Selective vpac2 receptor peptide agonists
US20080085860A1 (en) * 2004-08-18 2008-04-10 Eli Lilly And Company Selective Vpac2 Receptor Peptide Agonists
WO2007101146A2 (en) * 2006-02-28 2007-09-07 Eli Lilly And Company Selective vpac2 receptor peptide agonists
CN101484468A (zh) * 2006-07-06 2009-07-15 霍夫曼-拉罗奇有限公司 新型血管活性肠肽类似物
CN101906144B (zh) * 2009-06-03 2013-06-19 首都医科大学 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
SG10201407329RA (en) 2009-08-14 2015-01-29 Phasebio Pharmaceuticals Inc Modified vasoactive intestinal peptides
US9782454B2 (en) * 2010-04-22 2017-10-10 Longevity Biotech, Inc. Highly active polypeptides and methods of making and using the same
US9561262B2 (en) 2011-06-06 2017-02-07 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
US9789164B2 (en) 2013-03-15 2017-10-17 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
GB201421647D0 (en) * 2014-12-05 2015-01-21 Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
CN114652817A (zh) 2015-02-09 2022-06-24 费斯生物制药公司 用于治疗肌肉疾病和病症的方法和组合物
KR102243870B1 (ko) 2016-09-30 2021-04-22 후지필름 가부시키가이샤 환상 펩타이드, 어피니티 크로마토그래피 담체, 표지화 항체, 항체 약물 복합체 및 의약 제제

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
US4835252A (en) * 1987-02-26 1989-05-30 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
GB8729802D0 (en) * 1987-12-22 1988-02-03 Beecham Group Plc Novel compounds
US5084442A (en) * 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5141924A (en) * 1989-06-30 1992-08-25 Hoffmann-La Roche, Inc. Synthetic vasoactive intestinal peptide analogs

Also Published As

Publication number Publication date
FI20002041A (fi) 2000-09-15
KR970001580B1 (ko) 1997-02-11
CZ281818B6 (cs) 1997-02-12
EP0536741A3 (xx) 1994-04-06
CN1153785A (zh) 1997-07-09
JPH05213996A (ja) 1993-08-24
SK279399B6 (sk) 1998-11-04
ES2082317T3 (es) 1996-03-16
BG61125B2 (bg) 1996-11-29
HU211534A9 (en) 1995-12-28
CA2080272C (en) 2002-09-17
US5677419A (en) 1997-10-14
CN1152579A (zh) 1997-06-25
RU2095368C1 (ru) 1997-11-10
CN1225473C (zh) 2005-11-02
ATE132165T1 (de) 1996-01-15
UY23488A1 (es) 1993-04-20
UY25084A1 (es) 1998-12-21
SK308692A3 (en) 1995-03-08
NZ244644A (en) 1995-04-27
EP0536741A2 (en) 1993-04-14
NO304523B1 (no) 1999-01-04
CA2080272A1 (en) 1993-04-12
HUT62606A (en) 1993-05-28
TW305846B (xx) 1997-05-21
NO923929L (no) 1993-04-13
DE69207138D1 (de) 1996-02-08
CN1198841C (zh) 2005-04-27
FI111646B (fi) 2003-08-29
NO975023D0 (no) 1997-10-31
GR3019326T3 (en) 1996-06-30
CN1034943C (zh) 1997-05-21
KR930007972A (ko) 1993-05-20
IL103396A0 (en) 1993-03-15
AU656230B2 (en) 1995-01-27
FI924580A0 (fi) 1992-10-09
HU9203194D0 (en) 1992-12-28
AU2622892A (en) 1993-04-22
CN1072415A (zh) 1993-05-26
CZ308692A3 (en) 1993-08-11
NO975023L (no) 1993-04-13
NO980377L (no) 1993-04-13
IL117252A0 (en) 1996-06-18
JP2515473B2 (ja) 1996-07-10
DK0536741T3 (da) 1996-04-22
FI924580A (fi) 1993-04-12
DE69207138T2 (de) 1996-06-13
MX9205822A (es) 1993-06-01
EP0536741B1 (en) 1995-12-27
ZA927724B (en) 1994-04-07
NO923929D0 (no) 1992-10-09
IL117252A (en) 1999-11-30
NO980377D0 (no) 1998-01-28
BR9203959A (pt) 1993-04-27

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
RH1 Patent not in force