NO975023L - Vasoaktive cykliske polypeptider - Google Patents

Vasoaktive cykliske polypeptider

Info

Publication number
NO975023L
NO975023L NO975023A NO975023A NO975023L NO 975023 L NO975023 L NO 975023L NO 975023 A NO975023 A NO 975023A NO 975023 A NO975023 A NO 975023A NO 975023 L NO975023 L NO 975023L
Authority
NO
Norway
Prior art keywords
vasoactive
amino acid
peptide
peptide chain
side chain
Prior art date
Application number
NO975023A
Other languages
English (en)
Other versions
NO975023D0 (no
Inventor
David Robert Bolin
Margaret O'donnell
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO975023L publication Critical patent/NO975023L/no
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO975023D0 publication Critical patent/NO975023D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/17—Vasoactive intestinal peptides; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Det er beskrevet vasoaktive peptidanaloger (VIP) hvor sidekjede-karboksylterminalen av én aminosyre i peptid- kjeden er bundet kovalent til sidekjedeaminoterminalen av en annen aminosyre i peptidkjeden via dannelsen av en amidbinding. Den kovalente binding inellom de to amino- syreresiduer i peptidkjeden gir en ringstruktur. Fore- liggende forbindelser gir cykliske vasoaktive peptider og farmasoytiske blandinger omfattende slike cykliske vasoaktive peptider for behandling av bronkotrakiale sammentrekningslidelser.
NO975023A 1991-10-11 1997-10-31 Vasoaktive cykliske polypeptider NO975023D0 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77374791A 1991-10-11 1991-10-11

Publications (2)

Publication Number Publication Date
NO975023L true NO975023L (no) 1993-04-13
NO975023D0 NO975023D0 (no) 1997-10-31

Family

ID=25099195

Family Applications (3)

Application Number Title Priority Date Filing Date
NO923929A NO304523B1 (no) 1991-10-11 1992-10-09 Vasoaktive cykliske polypeptider
NO975023A NO975023D0 (no) 1991-10-11 1997-10-31 Vasoaktive cykliske polypeptider
NO980377A NO980377D0 (no) 1991-10-11 1998-01-28 Vasoaktive cykliske peptider

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO923929A NO304523B1 (no) 1991-10-11 1992-10-09 Vasoaktive cykliske polypeptider

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO980377A NO980377D0 (no) 1991-10-11 1998-01-28 Vasoaktive cykliske peptider

Country Status (26)

Country Link
US (1) US5677419A (no)
EP (1) EP0536741B1 (no)
JP (1) JP2515473B2 (no)
KR (1) KR970001580B1 (no)
CN (3) CN1034943C (no)
AT (1) ATE132165T1 (no)
AU (1) AU656230B2 (no)
BG (1) BG61125B2 (no)
BR (1) BR9203959A (no)
CA (1) CA2080272C (no)
CZ (1) CZ281818B6 (no)
DE (1) DE69207138T2 (no)
DK (1) DK0536741T3 (no)
ES (1) ES2082317T3 (no)
FI (2) FI111646B (no)
GR (1) GR3019326T3 (no)
HU (2) HUT62606A (no)
IL (3) IL117252A (no)
MX (1) MX9205822A (no)
NO (3) NO304523B1 (no)
NZ (1) NZ244644A (no)
RU (1) RU2095368C1 (no)
SK (1) SK279399B6 (no)
TW (1) TW305846B (no)
UY (2) UY23488A1 (no)
ZA (1) ZA927724B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872803B1 (en) 1993-09-21 2005-03-29 Kyowa Hakko Kogyo Co., Ltd. Peptides
ATE328004T1 (de) * 1996-02-09 2006-06-15 Hoffmann La Roche Herstellung eines vip-analogen
JP3647881B2 (ja) 1996-07-12 2005-05-18 イムノメディクス，インコーポレイテッド 放射性金属元素結合ペプチドの類似化合物
WO1998002453A2 (en) * 1996-07-15 1998-01-22 Universite Libre De Bruxelles Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor
US6972319B1 (en) 1999-09-28 2005-12-06 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use
WO2001023420A2 (en) * 1999-09-28 2001-04-05 Bayer Corporation Pituitary adenylate cyclase activating peptide (pacap) receptor 3 (r3) agonists and their pharmacological methods of use
US6489297B1 (en) 2000-02-18 2002-12-03 Dabur Research Foundation Vasoactive intestinal peptide analogs
CA2405714A1 (en) 2000-02-18 2001-08-23 Dabur Research Foundation Radiolabeled vasoactive intestinal peptide analogs for diagnosis and radiotherapy
US6828304B1 (en) 2000-07-31 2004-12-07 Dabur Research Foundation Peptides for treatment of cancer
US7507714B2 (en) * 2000-09-27 2009-03-24 Bayer Corporation Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
CN101229363A (zh) 2000-11-28 2008-07-30 蒙多生物技术许可股份公司 具有血管活性肠肽的生物学活性的用于治疗肺动脉和小动脉高压的化合物
CA2488358A1 (en) 2002-06-10 2003-12-18 Mondobiotech Laboratories Anstalt Use of compounds having the biological activity of vasoactive intestinal peptide for the treatment of sarcoidosis
US20090143283A1 (en) * 2004-01-27 2009-06-04 Bayer Pharmaceuticals Corporation Pituitary Adenylate Cyclase Activating Peptide (PACAP) Receptor (VPAC2) Agonists and Their Pharmacological Methods of Use
US20080085860A1 (en) * 2004-08-18 2008-04-10 Eli Lilly And Company Selective Vpac2 Receptor Peptide Agonists
CA2576755A1 (en) * 2004-08-18 2006-03-02 Eli Lilly And Company Selective vpac2 receptor peptide agonists
BRPI0708341A2 (pt) * 2006-02-28 2011-05-24 Lilly Co Eli agonistas peptìdicos seletivos do receptor vpac2
CN101484468A (zh) * 2006-07-06 2009-07-15 霍夫曼-拉罗奇有限公司 新型血管活性肠肽类似物
CN101906144B (zh) * 2009-06-03 2013-06-19 首都医科大学 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
PT3311828T (pt) 2009-08-14 2021-05-05 Phasebio Pharmaceuticals Inc Péptidos intestinais vasoativos modificados
US9782454B2 (en) * 2010-04-22 2017-10-10 Longevity Biotech, Inc. Highly active polypeptides and methods of making and using the same
WO2012170524A1 (en) 2011-06-06 2012-12-13 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
EP2968469A4 (en) 2013-03-15 2016-08-31 Longevity Biotech Inc PEPTIDES COMPRISING NON-ENDOGENIC AMINO ACIDS AND METHODS OF MAKING AND USING SAME
GB201421647D0 (en) 2014-12-05 2015-01-21 Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
CN114652817A (zh) 2015-02-09 2022-06-24 费斯生物制药公司 用于治疗肌肉疾病和病症的方法和组合物
EP4043479A1 (en) 2016-09-30 2022-08-17 FUJIFILM Corporation Cyclic peptide, affinity chromatography support, labeled antibody, antibody-drug conjugate, and pharmaceutical preparation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
US4835252A (en) * 1987-02-26 1989-05-30 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
GB8729802D0 (en) * 1987-12-22 1988-02-03 Beecham Group Plc Novel compounds
US5084442A (en) * 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5141924A (en) * 1989-06-30 1992-08-25 Hoffmann-La Roche, Inc. Synthetic vasoactive intestinal peptide analogs

Also Published As

Publication number Publication date
NO304523B1 (no) 1999-01-04
FI924580A0 (fi) 1992-10-09
DK0536741T3 (da) 1996-04-22
IL103396A0 (en) 1993-03-15
KR930007972A (ko) 1993-05-20
JP2515473B2 (ja) 1996-07-10
NO980377L (no) 1993-04-13
DE69207138T2 (de) 1996-06-13
JPH05213996A (ja) 1993-08-24
NO923929L (no) 1993-04-13
SK279399B6 (sk) 1998-11-04
FI20002041A (fi) 2000-09-15
GR3019326T3 (en) 1996-06-30
UY23488A1 (es) 1993-04-20
EP0536741B1 (en) 1995-12-27
US5677419A (en) 1997-10-14
CN1225473C (zh) 2005-11-02
TW305846B (no) 1997-05-21
IL103396A (en) 1997-11-20
NO980377D0 (no) 1998-01-28
ES2082317T3 (es) 1996-03-16
ZA927724B (en) 1994-04-07
HUT62606A (en) 1993-05-28
NZ244644A (en) 1995-04-27
AU2622892A (en) 1993-04-22
BR9203959A (pt) 1993-04-27
CA2080272C (en) 2002-09-17
EP0536741A2 (en) 1993-04-14
BG61125B2 (bg) 1996-11-29
IL117252A (en) 1999-11-30
FI924580A (fi) 1993-04-12
KR970001580B1 (ko) 1997-02-11
DE69207138D1 (de) 1996-02-08
ATE132165T1 (de) 1996-01-15
UY25084A1 (es) 1998-12-21
NO923929D0 (no) 1992-10-09
HU9203194D0 (en) 1992-12-28
AU656230B2 (en) 1995-01-27
CN1153785A (zh) 1997-07-09
SK308692A3 (en) 1995-03-08
CA2080272A1 (en) 1993-04-12
HU211534A9 (en) 1995-12-28
CN1198841C (zh) 2005-04-27
CN1072415A (zh) 1993-05-26
FI111646B (fi) 2003-08-29
CZ281818B6 (cs) 1997-02-12
IL117252A0 (en) 1996-06-18
RU2095368C1 (ru) 1997-11-10
NO975023D0 (no) 1997-10-31
MX9205822A (es) 1993-06-01
CN1034943C (zh) 1997-05-21
CN1152579A (zh) 1997-06-25
CZ308692A3 (en) 1993-08-11
EP0536741A3 (no) 1994-04-06

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application